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PubMed1999

Treatment of hypertrophy of the inferior turbinate: long-term results in 382 patients randomly assigned to therapy.

A number of surgical techniques are commonly performed to control the symptoms of inferior turbinate hypertrophy unresponsive to medical treatment. We report long-term results in 382 patients randomly assigned to receive electrocautery (62), cryotherapy (58), laser cautery (54), submucosal resection without lateral displacement (69), submucosal resection with lateral displacement (94), and turbinectomy (45). Outcomes of objective test results from rhinomanometry, acoustic rhinometry, mucociliary transport time, and secretory immunoglobulin A levels were compared to the symptom scores before and yearly after surgical treatment. These data indicate that submucosal resection with lateral displacement of the inferior turbinate results in the greatest increases in airflow and nasal respiratory function with the lowest risk of long-term complications.

Adolescent↗
PubMed1991

Cadaver studies of the anatomy of arterial supply to the inferior turbinates.

The anatomy of the arterial supply of the inferior turbinate was studied by dissection and serial histological sections. The arrangement was found to be constant, with a single main descending branch of the sphenopalatine artery entering its substance from above, 1-1.5 cm from its posterior border. This artery branches as it passes forwards within the turbinate, remaining close to the bone. As these pass anteriorly they give rise to arterial arcades which remain close to or within the bone, with the main artery increasing in diameter. The implications of these findings are discussed in a surgical context.

Arteries↗
PubMed2003

Turbinate atrophy evaluation in pigs by computed tomography.

Computed tomography (CT), a non-invasive visualisation technique was applied for imaging the bony structures of the nasal cavity of pigs, and compared to the traditional scoring system of turbinate atrophy in swine. Twenty-three 27-week-old pigs representing various stages of turbinate atrophy were used. Nasal structures were visually scored on CT scans and transversal cuts of the noses at the level of the first upper premolar teeth using the same scoring system in both cases. A tissue/air area ratio was also determined based on density differences. A highly significant correlation was found between visual scoring of CT images and transversal cuts of pig noses (r = 0.98, p < 0.0001) as well as between visual scoring of CT images and tissue/air area ratio determination (r = -0.82, p < 0.0001).

Animals↗
PubMedDate not supplied

Treatment of the obstructive nose by CO2-laser reduction of the inferior turbinates: technique and results.

In our department we treat chronically enlarged inferior turbinates (not responding to adequate medical therapy) with the CO2-laser or by partial inferior turbinoplasty. In this work the technique is described and short- and long-term results are evaluated. We divided our study group into two populations: one group with a follow-up of 18 months for which we could obtain objective measurements of the nasal patency by means of a preoperative and postoperative active anterior rhinomanometry, and another group with a follow-up of more than 15 years, for which (because of the absence of a pre-operative rhinomanometry) we could only obtain a subjective evaluation of the results by means of a questionnaire. Relief of nasal obstruction was reported by 88.5% of the patients until 5 years after laser surgery on the inferior turbinates. There seems to be no functional impairment on the nasal mucosa after this kind of surgery. The advantages and drawbacks of this technique are discussed.

Adolescent↗
PubMedDate not supplied

The inferior turbinate mast cell population of patients with perennial allergic and nonallergic rhinitis.

The number of mast cells in the inferior turbinates of patients with perennial allergic rhinitis and perennial nonallergic rhinitis was compared with normal controls. Mast cell counts expressed as the mean number in 100 high-power fields, assessed after Carnoy's fixation and toluidine blue staining were 1.84 in normal controls (n = 11), 4.39 in patients with perennial allergic rhinitis (n = 13), and 4.00 in those with perennial nonallergic rhinitis (n = 26). Statistical analysis confirmed that the density of mast cells in allergic as well as in nonallergic patients was significantly higher than in normal controls, whereas no significant difference was found between the number of mast cells in allergic and nonallergic patients. It is concluded that the number of mast cells in the inferior turbinate mucosa of patients with perennial rhinitis is increased compared with normal controls, and the increased number is not necessarily allergy-dependent.

Acetic Acid↗
PubMedDate not supplied

Goblet cell density of the inferior turbinates in patients with perennial allergic and nonallergic rhinitis.

Nasal mucus production is regulated by submucosal glands and epithelial goblet cells. The role and especially the number of the latter are quite debatable. The present study compares the distribution and density of goblet cells in the inferior turbinates of patients with perennial allergic and nonallergic rhinitis to normal controls. The periodic acid Schiff-alcian blue whole-mount method was used to identify and count their number. Goblet cell distribution was found nonhomogeneous, and considerable variations were observed among adjacent localities of the same specimen. The mean number of goblet cells per mm2 was 6499 in normal controls (n = 12), 6818 in patients with perennial allergic rhinitis (n = 13), and 6801 in patients with perennial nonallergic rhinitis (n = 18). Statistical analysis confirmed that the density of goblet cells did not differ significantly between patients with and without allergy, as well as between each group of patients and controls. Therefore, it could be concluded that the number of goblet cells in the inferior turbinate is not influenced by the presence of perennial allergic or nonallergic rhinitis.

Cell Count↗
PubMedDate not supplied

Radiofrequency bipolar submucosal diathermy of the inferior turbinates.

Fifty nonatopic patients with chronic hypertrophic rhinitis and suffering from chronic nasal obstruction due to hypertrophied inferior turbinates were subjected to bipolar submucosal diathermy using a radio frequency unit and a bipolar turbinate probe. One year postoperatively, 76% of patients showed significant improvement of their nasal breathing and another 16% reported partial improvement. The minimal cross sectional has also significantly increased from 0.58 +/- 0.05 cm2 to 0.72 +/- 0.04 cm2 and the decongestive effect was statistically significant. Electron microscopic examination of the nasal mucosa at the end of the follow up period revealed intact healthy epithelium as well as intense fibrosis of the underlying stroma. The results of the work showed that bipolar submucosal diathermy is a safe, effective outpatient procedure that does not require nasal packing or expensive instrumentation. The procedure can be repeated, if necessary, according to the patient's needs.

Biopsy↗
PubMed1983

Restricted energy intake and elevated calcium and phosphorus intake for gilts during growth. IV. Characterization of metacarpal, metatarsal, femur, humerus and turbinate bones of sows during three parities.

The effect of early nutrition on subsequent bone development was studied using gilts that had previously been fed ad libitum or 75% ad libitum intake and 100 or 150% National Research Council-recommended daily Ca and P from weaning to 100 kg. During the three-parity reproductive study, sows were fed a 14% protein diet. Metacarpals and metatarsals were taken from sows culled due to lameness or failure to breed and from sows after completing three parities. Femur and humerus articular cartilage and turbinates were described at necropsy. Metacarpals and metatarsals were heavier and tended to have thicker walls when sows were previously fed ad libitum or fed 150% Ca and P. Energy intake produced the greater response. Metacarpal breaking strength was greatest for sows previously fed ad libitum. Metatarsals were not affected by energy intake. Stiffness, Young's modulus of elasticity (YME) and flexural modulus for metacarpals and metatarsals were not affected by energy intake. Previously fed Ca and P intakes did not affect any of the mechanical bone characteristics. Metacarpals were heavier, had a greater breaking strength, were more elastic and exhibited slightly less resistance to bending than the metatarsals. The ether extract, ash, Ca and P content and the Ca:P ratio of metacarpals and metatarsals were not affected by previously fed energy or Ca and P intakes. The ether extract content tended to decrease and the ash, Ca and P content tended to increase with age. Articular cartilage and turbinate scores were not influenced by previously fed energy or Ca and P intakes. The YME and flexural modulus were the only bone characteristics that were even poorly correlated (average r = .25) with soundness scores, suggesting that high values result in poorer soundness scores. Energy and Ca and P intakes during growth and development had only minimal effects on bone characteristics and no apparent effect on structural soundness and longevity of sows kept for three parities.

Animals↗
PubMed1992

Newcastle disease viral infection in chicken nasal turbinate and maxillary sinus.

Newcastle disease virus (NDV) B strain was inoculated intranasally and intrasinusly into unanesthetized chicken which were maintained on a standard commercial mash chicken diet until the age of 21 days after hatch. The lesions induced by NDV following intranasal inoculation usually produced a selective destruction of significant portions of the inner surface of the turbinate scroll, but sinus lesions, though sometimes present in NDV infection, were not common. The chicken sinus was infected by intrasinus inoculation. These results were supported by the amount of virus and mucociliary transport time in the turbinate and sinus. It is suggested that mucus hypersecretion of ostial gland and/or mucociliary activity in the sinus be one of the most important factors in protecting against chicken sinus infection.

Animals↗
PubMed1991

A straight nasal septum and right unilateral hypertrophied inferior nasal turbinate, a very rare anatomical phenomenon, in skilled language translators: relevance to anomalous dominance, brain hemisphericity and second language acquisition.

Research on second language acquisition has recently focused on the concept of brain hemisphericity. Since the nasal cycle indexes brain hemisphericity and a deviated nasal septum itself affected by structural brain dominance may prevent nasal cycling, we investigated the presence of septal deviation and inferior turbinate hypertrophy in 11 expert translators. We found that 10 of the 11 subjects demonstrated both a straight nasal septum and right unilateral inferior turbinate hypertrophy, an extremely rare anatomical phenomenon. The one-tailed binomial test was extremely significant (p < .0000001). This anatomical phenomenon, which can be noninvasively checked in less than 30 seconds may predict excellence in second language acquisition.

Adult↗
PubMed2000

Rebuilding the inferior turbinate with hydroxyapatite cement.

This article describes a method of reconstructing a totally resected inferior turbinate with hydroxyapatite cement in patients who experience symptoms often associated with an overzealous resection of the turbinate (the "empty nose" syndrome).

Adult↗
PubMed2002

Septal-turbinate-suture in endonasal sinus surgery.

The middle turbinate (MT) is an important landmark in sinus surgery with specific functions in the nasal physiology. Because of postoperative instability and corresponding mucosal defects in the middle nasal meatus scar formations between the MT and the lateral nasal wall are frequent. Lateralization and scarring to the lateral nasal wall can be avoided by means of a resorbable mattress suture (septal-turbinate-suture (STS)) through the head of the MT and the septum.

Humans↗
PubMedDate not supplied

PCR analysis of nasal polyps, chronic sinusitis, and hypertrophied turbinates for DNA encoding bacterial 16S rRNA.

BACKGROUND: Nasal polyps are considered to result from chronic inflammation, but the initial or persisting stimulus for the inflammation is not known. A variety of bacteria and fungi have been cultured from nasal polyps, but approximately 35% have sterile cultures. Previously, Mycoplasma pneumoniae-specific DNA was detected in human nasal polyps using polymerase chain reaction (PCR) techniques, suggesting M. pneumoniae as a causative agent in the etiology of nasal polyps. METHODS: In this study, we tested for the presence of bacterial DNA in nasal polyps resected from 40 patients, in nasal mucosa membrane from 9 patients undergoing turbinectomy for hypertrophy, and in sinus mucosa membrane from 6 patients undergoing endoscopic surgery for chronic sinusitis. Tissue DNA was extracted and analyzed by PCR using M. pneumoniae specific primers for DNA that encode the 16S rRNA gene in 41 specimens (31 polyps, 6 turbinates, and 4 sinus), and by consensus sequence-based PCR using broad range primers for most eubacterial DNA encoding the 16S rRNA gene in 38 specimens (26 polyps, 7 turbinates, and 5 sinuses). RESULTS: Only two samples were positive for bacterial DNA encoding 16S rRNA: Streptococcus sp. DNA was isolatedfrom one polyp specimen and Pseudomonas aeruginosa DNA was isolated in one maxillary sinusitis specimen. No evidence of M. pneumoniae-specific DNA encoding 16S rRNA was found in any of the tissues. CONCLUSIONS: This study suggests that chronic bacterial infection is not a major component of nasal polyp etiology.

Base Sequence↗
PubMed2001

[The effect of submucosal diathermy to the inferior turbinates on nasal airway resistance].

OBJECTIVE: The main purpose of the study is to observe the effect of submucosal diathermy to the inferior turbinates on nasal airway resistance (NAR). METHOD: Using active anterior rhinomanometry, NAR were measured in seventeen patients who suffered from chronic rhinitis before and post operation. The subjective impression of their nasal patency was assessed using a 10-point scale. RESULT: The NAR is(0.662 +/- 0.22) kPa.s/L before operation and (0.302 +/- 0.17) kPa.s/L three months after operation. The NAR is 0.397 +/- 0.25 ten months after operation. The differences are statistically significant (P < 0.01) between the NAR before and post operation. There are significant differences in the subjective impression of patients' nasal patency as well (P < 0.01). CONCLUSION: Submucosal diathermy to the inferior turbinates is effective in decreasing NAR and improving the subjective impression of their nasal patency.

Adolescent↗
PubMed2002

[The effect of managements of middle turbinate on nasal airway resistance in endoscopic sinus surgery].

OBJECTIVE: To study the influence of different managements of middle turbinate on nasal airway resistance(NAR) and nasal airflow sensation. METHOD: Patients were divided into three groups: total resection group (32 patients/sides), partial resection group (37 patients/sides) and total reservation group (34 patients/sides). The NAR and nasal airflow sensation were measured with anterior rhinomanometer and visual analogue scale test (VAS) respectively. RESULT: The NAR and VAS scores decreased significantly after operation (P < 0.01). But there was no significant difference between these three groups(P > 0.05). CONCLUSION: The different managements of middle turbinate have no significant influence on NAR and nasal airflow sensation.

Adult↗
PubMedDate not supplied

[Positional rhinomanometry in hypertrophic vasomotor chronic rhinitis: considerations before and after functional surgery of turbinates].

The Authors report their experience regarding Positional Active Rhinomanometry performed before and after surgery in hypertrophic-vasomotor chronic rhinitis. Twenty-five patients suffering of hypertrophy of the turbinates and/or nasal vasomotor disorders were examined pre-operatively and 3, 6 and 12 months after inferior submucosal turbinoplasty. Tests were performed in the seated, supina, homolateral and contralateral positions with regard to the fossa in question. Values were compared with those of forty normal subjects. Pre-operative examinations showed a large number of paradoxical responses and very high increase in nasal resistance. Postoperative values were quite similar to those of normal subjects, a demonstration of the efficacy of surgical treatment of turbinates hyper-reactivity.

Adult↗
PubMed2003

Concha bullosa of an inferior turbinate.

Pneumatization of the inferior turbinate is a rare intranasal anatomic variant. In the English-language world literature, only 10 cases of inferior turbinate concha bullosa have been reported. We present the 11th such case, which we discovered during an evaluation of a patient who had chronic rhinosinusitis with allergic manifestations.

Adult↗
PubMed2003

Localization of the atrial natriuretic factor in the human inferior turbinates. An immunohistochemical study.

In man, the architecture of the turbinates is able to modify some of the physiochemical characteristics of the air inhaled. These modifications depend on the nervous system and on the action of neurotransmitters such as vasoactive intestinal peptide. Substance P, calcitonin gene-related peptide and other neuropeptides. As atrial natriuretic factor has been detected in the trachea and lung, the present immunohistochemical study was carried out to establish the presence and localisation of the atrial natriuretic factor on the inferior turbinates of the human being. The findings show atrial natriuretic factor to be present in the serous epithelial cells and in some cells of the tonaca propria near the sinusoids and the arteriovenous shunts and the acinar cells of the glands. Atrial natriuretic factor, therefore, could play a part in the stratification of mucus on the luminal surface and also regulate the blood flow of the capillaries, modifying, in this way, the physiochemical features of the air inhaled.

Atrial Natriuretic Factor↗