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PubMedDate not supplied

[Syndrome of enlarged thymus gland in children with congenital heart defects].

Material of the study represents samples of the enlarged thymus of 40 children aged from 1 month to 3.5 years obtained during surgery on the open heart. A thymus enlargement in the majority of children with heart malformations was due to its reactive hyperplasia similar to the first stage of acute (accidental) involution or changes observed in the thymus in the "rebound" phenomenon. In some cases B-lymphocytic hyperplasia was observed which is considered as a sign of the autoimmune disturbances.

Child, Preschool↗
PubMed1979

[Histoenzymological characteristics of changes in the thymus gland in xenogenous form of graft vs host reaction].

The structural and functional lesions in the thymus of newborn animals in which xenogeneic graft versus host reaction was produced. Against the background of thymus hypoplasia, a decrease in mitogenesis and a reduction in the number of metabolically active lymphocyte forms were found. At the same time, activation of reticuloepithelial cells, macrophages, and giant cells was observed. It is assumed that such changes in the thymus may reflect an adaptative reaction of the host directed at making up the deficiency of peripheral T-lymphocytes developing in GVHR.

Animals↗
PubMed1984

[Functional activity of the thymus gland and pituitary-adrenal system in patients with malignant skin melanoma].

Essential changes in the thymus functional condition and hypophyseal-adrenal system were revealed in patients with skin melanoma. The secretory activity of the thymus loosens, and there is a reduction of thymic hormone titer in blood. The increased levels of ACTH and hydrocortisone in blood indicate an enhanced activity of the hypophyseal-adrenal system under this pathology.

Adrenocorticotropic Hormone↗
PubMed1983

[Recovery of hematopoiesis in mice following a continuous irradiation with a dose rate of 0.957 Gy/d and a total accumulated dose of 19.14 Gy. I. Bone marrow, spleen and thymus gland].

This paper deals with the evaluation of histological changes in the bone marrow, spleen and thymus of mice after continuous irradiation with a dose rate of 0.957 Gy/day and a total accumulated dose of 19.14 Gy. Erythropoiesis in the spleen could be recovered quickly, significantly exceeding the spleen erythropoiesis of the controls on the seventh post-irradiation day. Myelopoiesis in the bone marrow could be recovered until the 21st day and erythropoiesis until the 28th day after the end of irradiation. Lymphopoiesis in the thymus could be recovered on the 28th day approximately and in the spleen roughly on the 60th day after the end of irradiation.

Animals↗
PubMed1979

[Effects of ionizing radiations on the ultrastructure of the thymus gland].

Different doses of gamma rays induce ultrastructural alterations in limphoid and epithelial cells of the chick thymus which exhibit a different temporal evolution after the treatment. The main changes which occur in lymphoid cells treated with 50 rads disappear 48 hours after the irradiation, while with 100 rads the radiation damage is still evident in epithelial cells.

Animals↗
PubMedDate not supplied

Cervical thymus gland.

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Congenital Abnormalities↗