Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “SENSATION”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 325 records · Page 18Linked to original sources
PubMed1998

[Sensation seeking--critical review of personality psychological concepts and its application].

The term "sensation seeking" is part of a self-contained theory on personality psychology. It is meant to denote a disposition--peculiar to a certain personality, probably genetically founded and correlating with biological, f. e. neuroendocrine measures--to explore one's social environment in order to find new and diversified stimuli. In their work, researchers mainly refer to Zuckerman's Sensation Seeking Scale in its fifth version (SSS-V), which distinguishes between four aspects of sensation seeking based on factor analysis of the 40 SSS-V-items. There is partly an overlapping of the phenomenon with impulsiveness and extraversion. Whereas application studies show inter alia links between sensation seeking and dangerous driving or dangerous sexual practices, data on the expression of this trait in addictive persons do not point to definitely consistent links. In forensic terms, there is on a link between "boredom susceptibility"--the inability to stand uneventful, monotonous situations--and "disinhibition"--a lack of control of impulses--figuring as subscales of the SSS-V, on the one hand, and hyperkinetic attention deficit syndromes and "disactualisation weakness", as described by Janzarik, on the other. At present, there is no German-language SSS-inventory in line with basal testing theory requirements. Because of the apparently different modi of sensation seeking influenced by other cultural traditions, such a scale must be basically adapted to the life-style in Western Europe.

Exploratory Behavior↗
PubMed1992

The female sensation seeker and marital sexuality.

To examine the role of sensation seeking in female sexuality, the Zuckerman's Sensation Seeking Scale was administered to a nonclinical population of married women. Comparative assessments were made between two matched samples of high and low sensation seekers on frequency of sexual intercourse, marital satisfaction, sexual desire, sexual arousal, sexual assertiveness, sexual attitudes, and sexual satisfaction. Although the high sensation seekers demonstrated significantly greater sexual desire, sexual arousability, and a more positive attitude toward sex, there were surprisingly no differences between the groups on frequency of sexual intercourse and sexual assertiveness. Also, the women classed as low sensation seekers reported greater marital and sexual satisfaction.

Exploratory Behavior↗
PubMed2006

The electrophysiology of de qi sensations.

OBJECTIVE: The objective was to investigate the effect of three different modes of stimulation on: (1) the electrical conductance of a known acupuncture point (AP) and a point with no known acupuncture function (NP); and (2) the corresponding characteristics of de qi sensations. DESIGN: The design was prospective. SETTINGS AND LOCATIONS: Healthy subjects were recruited for the study at the University of California, San Diego Medical Center. Subjects and Study Interventions: Fifteen subjects were enrolled. Two locations of the subjects' nondominant hand were marked: (1) AP (Li4); and (2) NP, a control location with no known acupuncture function. The following different stimulation paradigms were applied to the testing sites in a randomized fashion: (1) transcutaneous electrical stimulation via an ECG electrode; (2) manual stimulation via an acupuncture needle; and (3) electrical stimulation via an acupuncture needle. All electrical stimulation was provided at 12 V and 5 Hz for 30 seconds. OUTCOME MEASURES: The conductance before and after each stimulation were measured. The subjects were asked to choose four most predominant descriptors of the de qi sensation after the stimulation and to rate the corresponding intensity on a linear VAS. RESULTS: The conductance values at the AP site are generally a bit higher than conductance values at the NP site for each given stimulation type. The de qi VAS score increased significantly after needle electrical stimulation (EA) in comparison to electrode or manual stimulation at both sites. The most predominant (incidence >30%) de qi sensation with electrical stimulation in either electrode or needle electrical stimulation was tingling, whereas in the manual stimulation, aching was the most predominant sensation of de qi. CONCLUSIONS: The de qi sensation appears to be qualitatively and quantitatively different between manual and electrical stimulation. The observed difference in transcutaneous electrical conductance between.

Acupuncture Points↗
PubMed2002

Breast reconstruction using the sensate latissimus dorsi musculocutaneous flap.

The authors performed immediate breast reconstruction on four patients using a sensate latissimus dorsi musculocutaneous flap accompanied by neurorrhaphy during the past 6 years. In the neurorrhaphy, the lateral cutaneous branch of the dorsal primary divisions of the seventh thoracic nerve, which controls the sensation of the myocutaneous flap, was anastomosed to the lateral cutaneous branch of the fourth intercostal nerve, which controls the sensation of the breast. The subjects consisted of four patients whose postoperative follow-up period was 14 to 29 months, with an average of 19.3 months. The control subjects consisted of 10 cases with a latissimus dorsi musculocutaneous flap whose sensory nerve had not been reconstructed (postoperative follow-up period, 15 to 49 months; average, 26.9 months). The sensory examination included tests of touch, pain, and temperature. The innervated musculocutaneous flap sensation showed gradual recovery at about 6 months after surgery and reached the value of the normal side after about 1 year. In the control subjects, the recovery was gradual after more than 1 year and reached the value of the normal side in only some of the control subjects. On the basis of these findings, the authors consider the present technique to be useful for the recovery of sensation in immediate breast reconstruction.

Back↗
PubMed2003

Association between dopamine receptor D1 gene DdeI polymorphism and sensation seeking in alcohol-dependent men.

BACKGROUND: Among genetic and biopsychological factors involved in alcohol-dependence vulnerability, dopamine receptor subtypes genes and temperament's dimensions, such as sensation seeking, have been particularly incriminated. Moreover, it is suggested that higher levels of sensation seeking could be associated with a modification of sensitivity to dopamine in postsynaptic receptors. METHODS: We investigated whether the DRD1 DdeI polymorphism could be associated with the sensation-seeking level among a sample of 72 alcohol-dependent male and female patients. Analyses of variance were performed to test for an effect between the DRD1 DdeI genotypes and sensation-seeking scores according to the 40-item Zuckerman scale. RESULTS: When comparing the DRD1 DdeI genotypes and the Zuckerman scores, we found a significant association only in men (p = 0.01). CONCLUSIONS: That is the first report of a male limited association between the DRD1 gene polymorphism and sensation-seeking score in alcohol-dependent subjects.

Adult↗
PubMed2003

Impact of rectal distention on the results of evaluations of lower urinary tract sensation.

PURPOSE: To our knowledge no systematic studies have been performed in humans to test the interaction of normal bladder and rectal sensory function. However, symptoms affecting the different pelvic viscera often coexist. MATERIALS AND METHODS: In 15 healthy female volunteers sensations of bladder filling were evaluated during 2 consecutive cystometric studies, including 1 with an empty rectum and 1 with a full rectum. Similarly the electrical perception threshold was determined in the bladder when the rectum was empty and again when the rectum was full. RESULTS: Rectal distention did not change bladder compliance during filling. When the rectum was distended, sensations of bladder filling were reported at smaller volumes. On the other hand, electrical perception thresholds in the bladder were higher when the rectum was full. CONCLUSIONS: The state of the rectum significantly influences the sensations of bladder filling and electrical bladder stimulation. These results show that before sensory testing of the bladder rectal fullness should be examined and if necessary the rectum should be emptied. The different effect of rectal distention on filling and electrical sensations represents an additional argument for different innervation of the 2 sensations in the lower urinary tract.

Adolescent↗
PubMed2006

Depression, sensation seeking, and maternal smoking as predictors of adolescent cigarette smoking.

The purpose of this study was to examine maternal and adolescent depression, maternal and teen sensation seeking, and maternal smoking, and their associations with adolescent smoking. Data were collected from a sample of 47 male and 66 female adolescents (ages 11-18 years) and their mothers from three different health clinics. The findings indicated that maternal sensation seeking was linked indirectly with adolescent smoking through teen sensation seeking, both of which were significantly associated with teen smoking (beta = 0.29, p < 0.001 and beta = 0.32, p < 0.001, respectively). Teen depression was associated positively with teen smoking (beta = 0.24, p < 0.01) when controlling for sensation seeking behaviors. Maternal smoking was also directly linked to adolescent smoking (beta = 0.20, p < 0.05). These findings underscore a potentially important role of sensation seeking in the origins of adolescent smoking, and clarify pathways of influence with regard to maternal attitudes and behaviors in subsequent teenage nicotine use.

Adolescent↗
PubMed1995

The effect of nasal mucosal vasoconstriction on nasal airflow sensation.

The correlation between the objective measurement of nasal resistance and nasal airflow sensation is usually regarded as poor. To investigate the relationship between these two parameters 20 healthy volunteers had nasal resistance to airflow measured by rhinomanometry compared with nasal sensation by visual analogue scoring before and after nasal mucosal vasoconstriction using topical 0.1% xylometazoline. The median change in nasal resistance was 0.2 kPal-1s (95% CI 0.08-0.28 kPal-1s) and in nasal sensation 24 mm (95% CI 17 mm-35 mm). A significant relationship between nasal sensation and nasal resistance to airflow was found (Kendall's Rank correlation (P < 0.05). This function can be described by the linear regression equation: dS = 13.2 + 70.dNR where dS = change in nasal sensation and dNR = change in nasal resistance. There may be a much closer relationship between subjective and objective measures of nasal patency than has previously been thought.

Adult↗
PubMed1991

Sensation of effort and duration of mentally executed actions.

The aim of this study was to examine whether a sensation of effort would arise in subjects requested, by verbal instructions, to mentally perform motor tasks with an internal imagery strategy. Sixteen subjects had to imagine themselves, from a first person perspective, writing a sentence and drawing a Necker's cube either with their right dominant hand or with their left hand, as well as hopping around a square either on their right or left foot. The time needed to mentally execute these actions was measured. The sensation of effort following the mental performance and the difficulty of imaging the tasks were assessed by means of two analog rating scales. The results indicate that the sensation of effort increased across the trials. Furthermore, a negative correlation coefficient (mean r = -0.99) was found between the difficulty to imagining a given motor task and the subjective sensation of effort across the trials. Moreover, the sensation of effort was more pronounced when the tasks involved the non-dominant limb.

Adult↗
PubMed1992

The temporal locations of heartbeat sensations.

This experiment examined individual differences in the temporal location of heartbeat sensations and the reliability of their detection. Following practice on a familiarization task in judging light-tone simultaneity, 50 subjects were studied for two sessions on a heartbeat detection task, which required judging the simultaneity of heartbeat sensations and tones presented at six intervals following the onset of ventricular contraction. Subjects inspected the heartbeat-tone intervals as frequently and for as long as desired before choosing the one in which heartbeat sensations and tones were most simultaneous. The temporal locations of heartbeat sensations in subjects classified as "good heartbeat perceivers" (n = 16) ranged from 131 and 363 ms following ventricular contraction (mean = 228 ms). Correlations between the familiarization and heartbeat detection tasks in the accuracy of simultaneity judgments and in the frequency and duration of interval inspections suggest that general perceptual abilities and strategies may underlie success in detecting heartbeat sensations.

Adult↗
PubMed1989

Patterns of drug use and sensation-seeking among adolescents in Norway.

The relationship between personality and drug use was investigated by studying patterns of sensation-seeking behaviour and drug use among adolescents. A questionnaire was distributed to a sample of 1027 Norwegian senior high school students aged 16 to 19 in the greater Oslo area. The response rate was 97%. The sensation-seeking subscores showed moderate to strong association with the use of the different drugs. A canonical correlation analysis yielded 3 significant variates: in the drug use domain the first dimension correlated with the use of legal drugs and inhalants, the second with cannabis and tranquillizers and the third with tobacco. In the sensation-seeking domain the first dimension was almost synonymous with the disinhibition scale, the second with experience-seeking, and the third correlated highly negatively with thrill-, adventure- and experience-seeking. The results support the assumption that a strong link exists between sensation seeking and drug use. They further show the importance of taking different subdimensions of the sensation-seeking trait into account for prevention and treatment of drug use and abuse.

Adolescent↗
PubMed1990

The effects of oral administration of (-)-menthol on nasal resistance to airflow and nasal sensation of airflow in subjects suffering from nasal congestion associated with the common cold.

The effects of oral administration of a lozenge containing 11 mg (-)-menthol on nasal resistance to airflow (NAR) and nasal sensation of airflow in 62 subjects suffering from nasal congestion associated with naturally acquired common cold infection have been studied. NAR was measured by posterior rhinomanometry and nasal sensation of airflow by means of a visual analogue scale (VAS). The effects of the lozenge were compared with a candy placebo lozenge in a double blind randomized trial. NAR showed a significant increase (P less than 0.05) in both the menthol and placebo groups over the 2 h experiment with no difference between the groups at any time. The VAS scores showed significant changes of subjective improvement in nasal sensation of airflow (P less than 0.001) in the menthol-treated group 10 min after dosing whereas the placebo group showed no change. It is concluded that dosing with 11 mg menthol in subjects with common cold has no effect on NAR as measured by posterior rhinomanometry but causes a marked change in nasal sensation of airflow with a subjective sensation of nasal decongestion.

Administration, Oral↗
PubMed2006

Comparison of effects of vitamin E and wen-jing-tang (unkei-to), an herbal medicine, on peripheral blood flow in post-menopausal women with chilly sensation in the lower extremities: a randomized prospective study.

We examined the association between blood flow and chilly sensation in the lower extremities, comparing the changes in blood flow induced by the vitamin E and herbal therapy (Wen-jing-tang) in perimenopausal women with chilly sensation. One hundred sixty-one perimenopausal women aged 42-61 years (mean: 50.4 +/- 3.8 years) with chilly sensation in the lower extremities participated in the study. The participants were randomized for treatment with Wen-jing-tang or a vitamin E preparation containing 600 mg tocopherol nictinate per day for 8 weeks. Blood flow measurement was performed by laser Doppler fluxmetry to determine tissue under the jaw, in the middle finger, and in the third toe. Wen-jing-tang significantly increased the peripheral blood flow in the skin surface in the tiptoe (12.8 +/- 8.8, p = 0.0068) from basal levels (6.0 +/- 5.1), although no significant change was observed in the blood flow in fingertip or under the jaw during treatment. The rate of increase of blood flow in the skin surface of in the lower extremities was significantly higher in the Wen-jing-tang treating group (116.4 +/- 46.5%) than in the vitamin E group (39.8 +/- 21.3%) (p < 0.0001). When the effects of herbal treatment and vitamin E treatment were compared in the subjects with baseline upper extremity blood flow above the mean + 1.5 SD, mean blood flow through the upper extremities was found to have been significantly decreased after Wen-jing-tang treatment (from 57.7 +/- 4.8 to 43.1 +/- 4.2, p = 0.0277), whereas it remained unchanged after treatment with vitamin E. Classical monographs described Wen-jing-tang as being particularly useful in curing chilly sensation in lower extremities. The present study using a laser Doppler fluxmeter demonstrated that treatment with this herbal medicine significantly increased blood flow through the periphery of lower extremities in patients with chilly sensation. It also showed that this herbal medicine suppresses excessive blood flow through the upper half of the body and thus stimulates restoration of physiological distribution of blood flow throughout the entire body.

Adult↗
PubMed2001

Modulation of gastric distension-induced sensations by small intestinal receptors.

Duodenal lipid exacerbates gastrointestinal sensations during gastric distension. Using luminal application of the local anesthetic benzocaine, we investigated the role of intestinal receptors in the induction of these sensations. Nine healthy subjects were studied on five occasions, during which isotonic saline or 20% lipid (2 kcal/min), combined with (duodenal or jejunal) 0.75% benzocaine or vehicle at 2.5 ml/min, was infused intraduodenally before and during gastric distension. Intragastric pressures and volumes, gastrointestinal sensations, and plasma CCK levels were determined. Duodenal lipid combined with vehicle increased gastric volume (in ml: saline, -10 +/- 18; lipid/vehicle, 237 +/- 30) and plasma CCK [mean levels (pmol/l): saline, 2.0 +/- 0. 2; lipid/vehicle, 8.0 +/- 1.6] and, during distensions, induced nausea (scores: saline, 3 +/- 2: lipid/vehicle, 58 +/- 19) and decreased pressures at which fullness and discomfort occurred. Duodenal but not jejunal benzocaine attenuated the effect of lipid on gastric volume, plasma CCK, and nausea during distension (135 +/- 38 and 216 +/- 40 ml, 4.6 +/- 0.6 pmol/l and not assessed, and 37 +/- 12 and 64 +/- 21 for lipid + duodenal benzocaine and lipid + jejunal benzocaine, respectively) and on pressures for sensations. In conclusion, intestinal receptors modulate gastrointestinal sensations associated with duodenal lipid and gastric distension. There is also the potential for local neural mechanisms to regulate CCK release and thereby reduce afferent activation indirectly.

Adult↗
PubMed1997

Respiratory effort sensation during exercise with induced expiratory-flow limitation in healthy humans.

Nine healthy subjects (age 31 +/- 4 yr) exercised with and without expiratory-flow limitation (maximal flow approximately 1 l/s). We monitored flow, end-tidal PCO2, esophageal (Pes) and gastric pressures, changes in end-expiratory lung volume, and perception (sensation) of difficulty in breathing. Subjects cycled at increasing intensity (+25 W/30 s) until symptom limitation. During the flow-limited run, exercise performance was limited in all subjects by maximum sensation. Sensation was equally determined by inspiratory and expiratory pressure changes. In both runs, 90% of the variance in sensation could be explained by the Pes swings (difference between peak inspiratory and peak expiratory Pes). End-tidal PCO2 did not explain any variance in sensation in the control run and added only 3% to the explained variance in the flow-limited run. We conclude that in healthy subjects, during normal as well as expiratory flow-limited exercise, the pleural pressure generation of the expiratory muscles is equally related to the perception of difficulty in breathing as that of the inspiratory muscles.

Adult↗
PubMed2003

Microstimulation in the region of the human thalamic principal somatic sensory nucleus evokes sensations like those of mechanical stimulation and movement.

We explored the region of human thalamic somatic sensory nucleus (ventral caudal, Vc), corresponding to monkey ventral posterior (VP), with threshold microstimulation (TMIS) during stereotactic procedures for the treatment of tremor. Of 122 sites in 116 patients (124 thalami) where mechanical (touch, pressure, and sharp) or movement [movement through the body (movement) and vibration] sensations were evoked, 72 sites were found in the core or in adjacent regions, posterior-inferior (33), inferior (4), and posterior to the core (13). Sites where TMIS evoked touch were less frequently found in the core than those where movement or pressure sensations were evoked. Pressure was more commonly (P < 0.05) evoked than vibration at sites where cells had intraoral receptive fields (RFs). Touch and vibration were more commonly (P < 0.05) evoked than pressure at sites where cells had facial RFs, consistent with the relative density of rapidly adapting (RA) receptors in the mouth and face. Sites described as deep and movement were found superior and anterior in the core, consistent with the location of cells responding to stimulation of muscle afferents. At 72 of 122 sites, TMIS evoked the same sensation at two or more sites in the same plane. Of these sites, 58 are adjacent to each other, in a cluster, consistent with studies of the localization of cells responding to different modalities. These results demonstrate that mechanical and movement sensations can be evoked by stimulation in the region of Vc. The characteristics of these sites suggest that the sensations are evoked by stimulation of pathways specific to cutaneous and deep mechanoreceptors.

Analysis of Variance↗
PubMed1990

Responses of nociceptive SI neurons in monkeys and pain sensation in humans elicited by noxious thermal stimulation: effect of interstimulus interval.

1. Twenty-six nociceptive neurons in the primary somatosensory cortex (SI) of anesthetized monkeys were responsive to noxious thermal stimulation applied to the face. Thermode temperature increased from a base line of 38 degrees C to temperatures ranging from 44 to 49 degrees C (T1). After a period of 5 s, the temperature increased an additional 1 degree C (T2). The neuronal responses to noxious thermal stimuli were compared when the interstimulus interval (ISI) was 30 or 180 s. 2. A linear regression analysis was applied to the stimulus-response functions of neuronal responses to T1 stimuli obtained at ISIs of 180 s. Based on the slopes and linear regression coefficients of these stimulus-response functions, two populations of nociceptive neurons were identified. The neuronal responses of one population of nociceptive SI neurons (WDR1) to T1 stimuli were characterized by steep slopes and high regression coefficients, whereas the other population (WDR2) had flatter slopes and lower regression coefficients. WDR1 neurons responded with monotonic increases in neuronal activity as the stimulus intensity increased. However, the peak frequency of WDR2 neurons often reached a plateau below 47 degrees C. Both WDR1 and WDR2 neurons had receptive fields that encompassed one or two divisions of the trigeminal nerve. 3. The T1 neuronal responses of WDR1 neurons were significantly suppressed when thermal stimuli were delivered with ISIs of 30 s. The T1 neuronal responses of WDR2 and the T2 responses of both WDR1 and WDR2 neurons were not significantly different when ISIs of 30 and 180 s were used. The T1 thresholds of WDR1 and WDR2 neurons were significantly higher when stimuli were delivered with ISIs of 30 s compared with ISIs of 180 s. 4. Most nociceptive SI neurons were located in layers III and IV of area 1-2. In a number of instances, multiple nociceptive neurons were found in the same microelectrode penetration. 5. The humans' intensity of pain sensation paralleled the neuronal responses of nociceptive SI neurons. With the use of a similar paradigm as in the monkey experiments, increases in T1 and T2 temperatures resulted in monotonic increases in pain ratings and change in pain sensation, respectively. However, the intensity of pain sensation to T1 temperatures was suppressed by ISIs of 30 s. Neither ISI produced statistically significant changes in the intensity of pain sensation to T2 stimuli. 6. These data demonstrate that manipulations that alter the intensity of pain sensation also produce concomitant changes in the responsiveness of nociceptive SI neurons.(ABSTRACT TRUNCATED AT 400 WORDS)

Adult↗
PubMed1997

Human thalamic nucleus mediating taste and multiple other sensations related to ingestive behavior.

Until now, taste was the only primary sensory modality for which the human central nervous system pathways were unknown. We report sensations evoked by stimulation at microampere current levels in the region of the human thalamic nucleus (ventralis caudalis parvocellularis internis) corresponding to the monkey taste relay nucleus. Stimulation in this region during awake neurosurgical procedures evoked special visceral/somatic (taste/pungent smell), general visceral (fullness of a hollow viscus), as well as painful and nonpainful general somatic sensations. General somatic or visceral sensation was evoked by stimulation at 80% of sites where special visceral/somatic sensation was evoked. These results suggest that primate taste relay mediates multiple sensations in addition to taste.

Brain Mapping↗