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At least 325 records · Page 18Linked to original sources

Leiomyosarcoma of the urinary bladder: a case report.

A case of leiomyosarcoma of the urinary bladder occurring in a middle aged lady with immunohistochemical confirmation is presented for its rarity with emphasis on grading of smooth muscle neoplasms of the urinary bladder.

Diagnosis, Differential↗

[Metastases from hepatocellular carcinoma in a percutaneous access site for radiofrequency treatment: a case report].

Percutaneous radiofrequency ablation for hepatic tumours is a minimally invasive procedure associated with a risk of iatrogenic dissemination. Tumour seeding along the needle tract may generate neoplastic nodules and masses in the liver, peritoneum and abdominal wall. In this report we describe a case of a large metastatic lesion of the thoraco-abdominal wall after a radiofrequency ablation procedure for hepatocellular carcinoma.

Abdominal Wall↗

Schwannomatosis presenting as a painful gluteal swelling--a case report.

A 58 years old male came with a painful swelling in right gluteal region. On examination a small mass was found which was subsequently excised. Histopathological study reported presence of presumptive schwannomatosis, as there were 4 tumours composed of Antoni A and Antoni B areas along with Verocay bodies. As post-operative MRI scan of base of brain and ophthalmological examination of patient failed to reveal vestibular schwannomas and ocular stigmata of neurofibromatosis type 2 (NF-2) respectively, a final diagnosis of definite schwannomatosis was made.

Humans↗

[Two cases of primary skeletal muscle lymphoma, and a review of the literature].

Here we report two cases of primary skeletal muscle lymphoma. The first patient was an 82-year-old man. On April 2004, he was referred to our hospital because of swelling of the right upper arm. Magnetic resonance imaging (MRI) showed an area which was isointense on T1 and hyperintense on T2-weighted imaging compared with normal skeletal muscle. The size of the tumor was 5 x 7 x 13 cm. Following pathological, flow cytometric and genetic analyses of the specimen, we diagnosed the tumor as a non-Hodgkin lymphoma of the T-cell rich diffuse large B-cell type. The second patient was an 87-year-old man. He was admitted to our hospital on July 2004, under the chief complaint of swelling of the right thigh. MRI revealed a giant tumor mass of the right thigh which was isointense on T1 and hyperintense on T2 imaging. The patient was diagnosed by open biopsy as having diffuse large B-cell lymphoma. We could find only 62 cases of primary skeletal muscle lymphoma through a MEDLINE search. We report on our two cases with a review of the literature.

Aged, 80 and over↗

Proliferative myositis--a case report.

Proliferative myositis is a recently recognized and unusual reactive fibroproliferative lesion of striated muscle. It shows a bizarre cytological and histological appearance that can mimic a soft tissue sarcoma. It is important to recognize this pseudosarcomatous lesion so as to spare the patient anxiety and unnecessary surgery.

Child↗

[Mucinous tubular and spindle-cell carcinoma of the kidney].

4 cases (2 males and 2 females) of mucinous tubular and spindle-cell carcinoma of the kidney were studied. The patients' age was 43 to 87 years. Microscopically, this tumor comprised two major cell populations. One of them involved spindle cells with a sparse cytoplasm, which were arranged in the fascicular pattern, often resembling low-grade smooth muscle tumors. The other population was small cuboidal cells with round nuclei and an eosinophilic cytoplasm. The mitotic activity was low. Only one tumor had both cell components. The other three tumors were represented by the second type cells. Immunohistochemical staining with avidin-biotin was performed by using cytokeratin, vimentin, SMA, p53, Bcl 2, EMA, and CD10. All cases were stained positively with antibodies to the cytokeratins AE1-AE2 and vimentin. The expression of EMA, Bcl 2, and CK7 was varying in different tumors. Responses to smooth muscle actin, p53, CK20, and CD10 were negative in all cases. Mucinous tubular and spindle-cell carcinoma of the kidney should be differentiated from angiomyolipoma with the preponderance of a leiomyomatous component, renal smooth muscle neoplasms, metanephrotic adenoma, and renal cell carcinoma with sarcomatoid differentiation.

Adenocarcinoma, Mucinous↗

Chondroid lipoma--a case report.

Chondroid lipoma is a rare fatty tumor of soft tissues, especially in limbs and limb girdles. Though it is clinically benign, the main importance lies in its histological similarity with myxoid liposarcoma and chondrosarcoma, which have poorer prognosis. In our study, classical histological pattern of chondroid lipoma was confirmed on H&E and PAS stains with low mitotic count.

Adult↗

[Dermatomyositis as a paraneoplastic syndrome. A case report].

A female patient with dermatomyositis with the typical clinical findings of this disease, corresponding histological muscular changes and neurological findings is described. Since in the further course of the disease, recurrent gastric carcinoma was diagnosed, this case again emphasizes the significance of dermatomyositis as a paraneoplastic syndrome, and the need for tumor screening when dermatomyositis is diagnosed in advanced adulthood.

Aged↗

Smooth muscle tumors of the gastrointestinal tract. Flow cytometric quantitation of DNA and nuclear antigen content and correlation with histologic grade.

Simultaneous flow cytometric quantitation of DNA content and the proliferation-associated nuclear antigen p105 was performed on 41 gastrointestinal smooth muscle neoplasms and the results were correlated with histologic features. Aneuploid DNA stemlines were found in 17 cases (41%), including four of 15 (21%) tumors of unknown malignant potential, eight of 17 (47%) low-grade leiomyosarcomas, and five of seven (71%) high-grade leiomyosarcomas. In 10 of the 17 aneuploid tumors, an aneuploid peak was clearly identified on the single parameter DNA histogram, with a mean DNA index of 1.36. In the other seven aneuploid cases, a near-diploid, aneuploid population (mean DNA index, 1.08) was identified only by simultaneous immunofluorescence for p105. Clinical follow-up information was available for 14 patients. Mean survival of 10 patients with aneuploid tumors was 32 months, whereas mean survival of four patients with diploid tumors was 51 months. Of the seven patients who died within 1 year of diagnosis, six had aneuploid leiomyosarcomas. These findings demonstrate that DNA aneuploidy is common in high-grade gastrointestinal leiomyosarcomas and may be associated with shortened survival.

Antigens, Neoplasm↗

A malignant gastric leiomyoblastoma presenting as an infected pseudocyst of the pancreas.

Malignant gastric leiomyoblastoma (epithelioid leiomyosarcoma) is an uncommon smooth muscle neoplasm which is generally slow growing but capable of attaining large size. When these tumors project extrinsically from their site of origin in the gastric wall, they present diagnostic difficulty to the clinician and radiologist. This case report documents a highly unusual example of such a tumor which presented as an infected pancreatic pseudocyst and produced symptoms related to inferior vena caval compression.

Abscess↗

[Peripheral vascular leiomyosarcomas. Apropos of 2 cases].

The authors report here two observations of leiomyosarcomas arising from peripheral blood vessels. The first case occurred in the pedious vein and infiltrated into tarsal bones. The second case was localized into leg muscles' tendons, near the knee. The topographical and histological characteristics of peripheral vascular leiomyosarcomas are noted, and compared, according to the review of literature, with those of the great central blood vessels, and of other classical leiomyosarcomas.

Foot↗

Epithelioid leiomyosarcoma of the small intestine with oncocytic change.

We describe a 53-year-old woman who was found to have a large, ulcerated duodenal mass that on histologic examination was determined to be an epithelioid leiomyosarcoma and on ultrastructural studies contained a prominent component of cells with oncocytic change. To our knowledge, the findings in this case are unique, and on review of the literature, no similar cases of oncocytic change in smooth-muscle neoplasms of the gastrointestinal tract were found.

Adenoma↗