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Cancellous-marrow bone grafts in irradiated tissue.

Discontinuity defects of the mandible have been successfully treated by means of cancellous-marrow grafting techniques. This method of reconstruction has not been widely reported in the repair of defects in mandibles that have been exposed to radiation therapy. In the two cases presented in this article, the patients were previously treated for oral squamous-cell carcinoma by irradiation and partial mandibulectomy. Later, cancellous-marrow grafts were implanted. One patient received 3,000 rads of Cobalt-60 and had the body of the right mandible resected. The subsequent grafting procedure was successful in this patient. The second patient received 6,000 rads of Cobalt-60 and underwent resection of the mandible anterior to the molar region. The subsequent graft failed in this case.

Bone Marrow Cells↗

Cancellous bone marrow grafts in irradiated dog and monkey mandibles.

A pilot study was conducted to investigate the osteogenic potential of autogenous cancellous marrow grafts placed in irradiated tissue. Five dogs and three monkeys received either 4,100 or 6,520 rads of cobalt-60 irradiation during a 5- or 8-week period. Postirradiation discontinuity mandibular defects were created surgically and restored with autogenous cancellous bone marrow grafts held in position by a titanium mesh basket. Bony union occurred in all the mandibles. Intraoral ulceration was common in the dogs, and extraoral wound dehiscence was found in the monkeys. Hematopoietic marrow was present in the graft sites of both species 6 months to 1 year after surgery.

Animals↗

The use of stabilization plates in the immediate repair of defects following mandibular resection.

The results of immediate stabilization for surgical defects of the mandible in 18 patients are presented. Fourteen patients with malignant lesions underwent immediate stabilization without bone grafting, but with associated myocutaneous flap soft tissue reconstruction. Four patients with benign lesions were treated with immediate stabilization and bone graft reconstruction, but without myocutaneous flap soft tissue reconstruction. Results at from 4 to 34 months reveal two bone plates lost to massive intraoral exposure. The remaining plates remain in place with excellent functional and cosmetic results.

Bone Plates↗

Follow-up report of immediate stabilization of mandibular surgical defects after tumor resection.

This study constitutes a follow-up of a study completed in March 1988, involving 18 patients receiving bone plate stabilization for the repair of surgical defects after mandibular resection. An additional 11 cases are presented with follow-up periods of 3 to 23 months. Of the original study of 18 patients, follow-up was available for 13. Of these 13, five patients died, three as a result of their tumors. One patient was previously reported to have had recurrent disease and loss of the stabilization plate. One patient lost the plate in an area of recurrent tumor just before succumbing to his malignancy. The remaining three died with their stabilization plates in place and functioning. The eight remaining patients with long-term follow-up and 11 additional patients with shorter-term results are now described.

Bone Plates↗

Cerebrospinal fluid leak associated with proplast implant removal from the temporomandibular joint.

Severe bone erosion within the temporomandibular joint reconstructed with polytetrafluoroethylene implants is a well-recognized phenomenon. Although erosion into the middle cranial fossa has been reported, we know of no report of dural disruption with cerebrospinal fluid leakage. We report a case of cerebrospinal fluid leak noted at the time of PTFE implant removal and its subsequent management. Perforation of the contralateral glenoid fossa and its reconstruction is also reported.

Aged↗

Measurement of the heat of reaction transmitted intracranially during polymerization of methylmethacrylate cranial bone cement used in stabilization of the fossa component of an alloplastic temporomandibular joint prosthesis.

Temporomandibular joint alloplastic fossa replacements have always been difficult to stabilize because of the variability of the anatomy in the area both in normal and especially in pathologic states. Total joint reconstruction and stabilization in orthopedic surgery have been aided by the use of methylmethacrylate, which is used both as a cementing substance and as a filler material when there are voids between the implant and the basilar bone. The concept of the use of a filler material to aid in the stabilization of the alloplastic temporomandibular joint fossa is attractive, but of concern because of the exothermic reaction this material undergoes as it sets in proximity to the middle cranial fossa. This study was designed to measure the temperature gradient that exists in such a procedure when used with cadaver specimens. The results indicate that the heat of reaction was not significantly transmitted intracranially in the cadavers studied. However, I recommend care in the use of this material for this purpose with patients.

Bone Cements↗

Titanium lymph node pigmentation in the reconstruction plate system of a mandibular bone defect.

A case of titanium pigmentation that involved a submandibular lymph node is reported. A 41-year old man had been treated for ameloblastoma by partial resection of the mandible followed by reconstruction with the use of a titanium plate to bridge the mandibular defect. Titanium pigmentation occurred in the surrounding soft tissue adjacent to the plate and within a submandibular lymph node 2 years after reconstruction.

Adult↗

Preliminary report on use of a p(HEMA)-collagen composite in maxillo-facial surgery.

After being thoroughly tested on animals, a composite polymer material based on poly(2-hydroxyethyl methacrylate) and calf skin collagen has been allowed in a limited clinical trial in the Czech Republic. Up to now, the medical use of the biomaterial comprises implants for maxillo-facial surgery, i.e. augmentation of soft tissues (seven cases); reparation of fractured eye sockets (12 cases) and in special indications (two cases). The clinical results obtained so far are presented here as case reports. These preliminary results are very encouraging for a broader utilization of this type of biomaterial in the surgical fields of human medicine.

Adult↗

Augmentation genioplasty: when bone is not enough.

PURPOSE: Augmentation genioplasty is indicated to correct microgenia. When a large defect must be corrected, the additional use of a soft alloplastic implant may be indicated. METHODS: A 22-year-old patient is presented who required correction of microgenia. A 15-mm advancement of the chin was required to obtain an acceptable cosmetic result. RESULTS: An augmentation genioplasty achieved an 8-mm correction. This was supplemented by a silicone gel-filled implant inserted subperiosteally. This resulted in an outstanding cosmetic result. CONCLUSIONS: Chin contour is an important aspect of facial aesthetics. The sliding genioplasty is ideally suited for correcting most chin deformities; however, the insertion of an alloplast may augment patients with severe microgenia. Avoidance of the donor-site morbidity associated with the use of autogenous bone is a major benefit of this procedure.

Adult↗

Titanium mesh (TiMesh) osteosynthesis: a fast and adaptable method of semi-rigid fixation.

Titanium mesh has been used in the USA for the fixation of fractures of the facial skeleton since the Vietnam war. Despite the increasing use of titanium mesh osteosynthesis for trauma, orthognathic and reconstructive surgery in the USA, it is only in recent years that it has gained acceptance in Europe. This paper appraises the original titanium mesh osteosynthesis system (TiMesh) in a wide range of surgical contexts in the maxillofacial region. It has been found to be quick and reliable in placement, highly adaptable and to have considerably reduced the operating time. Its further potential advantages in reducing stress-shielding and improving functional bone healing due to its semi-rigid nature are discussed.

Bone Screws↗

Comparison of Silastic and Proplast implants in the temporomandibular joint after condylectomy for osteoarthritis.

This study was undertaken to compare the long-term stability of Silastic and proplast when used as alloplastic implants following high condylectomy. Twelve patients with osteoarthritis of the temporomandibular joint (TMJ) were treated either unilaterally or bilaterally. The follow-up period ranged from one to four years. In all ten TMJs that received Silastic implants and in ten that received Proplast implants, there were no discernible differences relative to comfort, masticatory function, or TMJ mobility. Although Silastic and Proplast had similar functional characteristics, Proplast implants had better long-term stability than the Silastic implants.

Adult↗