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Risk management in chemical safety: some general observations relating to the state of the art.

Risk management for chemical safety begins with judgement and produces arbitrary regulations. In between, technical risk assessment has value in clarifying the behaviour of particular chemical risk systems. Risk quantification can be useful in some cases and quite misleading in others. In no case can it alone be the decisive factor. In the public's perception, chemicals are feared most for potential insidious exposure in the general environment. Risk management then must deal with high system uncertainty and information heavily influenced by value judgements. The technical contribution to risk assessment is reduced, in real terms, as the decision-making scenario expands with its increasing exposure to system 'noise', interference and misinformation. Improved communication in the system requires the use of simplified language. The suitability of risk estimation methodologies must be assessed in terms of general comprehensibility in the management for chemical safety will remain, perhaps always, more of an art than a science, concerned with an interplay of information that can be 'rationalised' with other information that defies such rationalisation.

Communication↗

[Gadamer: grounding a proposal for the study of stress in the surgical center].

This article makes a reflection on philosophical foundation to support the methodology in order to study the stress of professionals who work in the operating theater. The qualitative research allows a comprehensive access to the world of each subject, revealing the individual perception of whom experiences the phenomenon. Gadamer understands that the language reveals and is suitable to evaluate properly, through hermeneutics, the symbolic dimension of the subject's speech. Hermeneutics is not only just a theory of the comprehension and interpretation art but much more than that, it is close to the practical philosophy, having to respond for the methodological feature of things whose understanding it provides.

General Surgery↗

[Scientific role of German ophthalmology in the European telecommunication project OPHTEL].

BACKGROUND: In Denmark, France, Germany, Great Britain and Italy, the OPHTEL project combines clinical centers of ophthalmology and internal medicine, an institute for medical informatics and health services research, a publishing company and different industrial partners in the EDP market. AIMS: With the aid of visual telecommunication and rapid data transfer, methods and conditions will be developed and proved so that any physician can very easily obtain sufficient information for treating his patient. Thus, the regional differences in the quality of structured health service (e.g., urban/ rural) will be overcome throughout Europe. SCIENTIFIC TASKS: A multilingual diagnostic and therapeutic thesaurus has to be worked out in order to create standards for communication and quality control. Based on literature, images and image analysis in a knowledge-based data bank, a monitoring system (containing watch-dog functions) and the basic aspects of an ophthalmological patient/disease register will be investigated. (In parallel, a technical development of synchronous and asynchronous telecommunication between eye physicians is taking place in close cooperation with the regional Bavarian project Teleopathalmology in Bavaria on-line). RESULTS: State of the art 6 months after starting the project:the knowledge-based image data bank has been founded and also an ophthalmological 8 language thesaurus and definition standard. All data transfer lines are installed. DISCUSSION: The project is taking place amid diverging sections of medicine: ophthalmology and internal medicine, health politics and data protection, individual treatment and common interest (health care), product management and office organization. Thus, the scientific quality of the transferred ophthalmological content must undergo sophisticated controls. FUTURE STEPS: Intense cooperation with the big German associations for ophthalmology (DOG, BVA) and the European ophthalmological societies concerning EDP, classification and quality control.

Computer Communication Networks↗

Temperament profiles in physicians, lawyers, managers, industrialists, architects, journalists, and artists: a study in psychiatric outpatients.

BACKGROUND: With the possible exception of cyclothymia in artists, there is a paucity of data in the literature on the temperament in different professions. METHODS: For this exploratory study, we sought to generate preliminary data on temperaments among psychiatric outpatients, including physicians (n=41), lawyers (n=30), managers and executives (n=35), industrialists (n=48), architects (n=27), journalists (n=34), and a mixed group of artists (n=48). They were compared with age, sex, social class, and affective disorder matched outpatients outside of these professions, drawn from the same clinical settings to serve as our Comparison Group (CG, n=120). We used an interview version of the Akiskal-Mallya criteria for temperaments. We finally used the DSM-III-R obsessive compulsive personality (OC traits). RESULTS: Compared with the CG, lawyers and physicians had high rates of dysthymic temperament and OC traits. Managers, like lawyers and doctors, had high rates on OC traits but were different in being very low on cyclothymic and twice as hyperthymic than the CG was. Industrialists, who, by definition, were self-made, had even higher rates of hyperthymic traits. Both architects and artists seemed to have benefited from being cyclothymic (3-4 times higher than CG's); interestingly, architects had higher levels of OC traits, and artists were less obsessional than the CG was. Overall, among managers/executives and lawyers, 41% met criteria for affective temperaments, whereas the equivalent rate among the remainder was 77%. LIMITATION: Given that this is a chart review of existing clinical records, it was not possible to be blind to the profession of the patients. A mixed group of artists may have obscured differences among artists from different domains of art (e.g., poets vs. performing artists), and the same can be said of physicians (e.g., internists vs. surgeons). A disclaimer would be appropriate: Ours is not a study on eminence in the different professions but on the temperament and personality profiles that distinguish among them. CONCLUSIONS: Despite the foregoing limitations and overlapping attributes in the different professions, they nonetheless emerged as having distinct temperamental and personality profiles. Dysthymic and obsessional attributes are notable in lawyers and physicians. We confirm the role of cyclothymia in artists and architects. The role of the hyperthymic temperament in managers, self-made industrialists, and journalists, to the best of our knowledge, is being reported for the first time. The role of cyclothymic and hyperthymic temperaments appears to be moderated by obsessional traits across the entire professional realm examined. In particular, artists' creative imagination appears "liberated" by low levels of OC traits, whereas among architects, relatively high levels of OC traits seem to contribute to the execution of their work. More tentatively, judging from the overall levels of affective temperaments in the remaining professions, on average, more of the managers/executives than self-made industrialists could be described as "colder" in temperament, and more of the physicians "warmer" than lawyers are. Journalists, as a group, appeared to possess the broadest representation of affective temperaments. The foregoing conclusions must be regarded as tentative, even hypothetical, in need of verification among professionals without major psychiatric disorders. Nonetheless, temperament profiles among psychiatrically ill professionals in the seven professional realms studies can help predict how they relate to their doctors, family members, colleagues, coworkers, and clients/patients. Such knowledge, in turn, can help the therapeutic process.

Administrative Personnel↗

How is emergent writing based on drawing? Analyses of children's products and their sorting by children and mothers.

Writing and drawing produced by children 28-53 months old were compared. Israeli and Dutch preschoolers were asked to draw and write, to classify their products as drawing and writing, and to decide what they had drawn or written. Israeli and Dutch mothers classified the products. Scores on a scale for writing composed of graphic, "writing-like," and symbolic schemes showed improvement with age. Recognition of drawings as drawings preceded recognition of writings as writings. Scores on writing and drawing were substantially correlated, even with age partialed out, suggesting (a) that when children start drawing objects referentially, they write by drawing "print" and (b) that progress in object drawing involves progress in drawing print, so that their writing becomes more writing-like. Children unable to communicate meaning by writing spontaneously resort to drawing-like devices, indicating the primacy of drawing as a representational-communicative system.

Art↗

[The role of Hunayn, physician and translator].

Hunayn ibn Ishāq is one of the most important translators of scientific and medical texts in the 'abbāsid era. He played a fundamental role in the transmission of Greek medical science to the Arab world, because of his deep knowledge of the Syriac, Arabic and Persian languages. He translated about 300 texts, especially medical ones, and he founded a school in which many disciples were instructed in the art of translation, like his son Ishāq and his nephew Hubays. Hunayn composed a lexicon of scientific terminology, using a new method of translation which represents his great innovation.

Arab World↗

The speech of reality and the speech of the stage: life, science and art.

Word is the most frequent way of communication in the human experience. As a mean of communication it influences the sentence formulation, which ought to be the autochthonous expression of thoughts. The experience teaches us that it is necessary to be a sovereign master of our own thoughts and of sentiments of others. This is one of the fundamental postulates of the communication in the word category. To speak correctly means to think correctly and that, on the other hand, means in the grammatical, lexical and stylistic aspect to be able to create a sentence as a way of getting across the thoughts, ideas and contents of the spirit. The community mentality, the person's characteristics (the temper, the type and the intensity), the education level, the range of the knowledge and the volume of their potentially creative synthesis determine the lexical richness and the amplitude of the use and the application of the language with the aim of establishing a high quality communication with words as a basic mean of that process. Within this context a word has its impressive and expressive dimensions. Its impressive dimension is created by the common reliance on the frequency of the use of some lexical possibilities and their variations. It is an individual characteristic of the spoken and the written output of every person and it also determines the singularities of a person's style, to that extent that it helps to detect the author of a text with a high percentage of accuracy even in the cases where the author is unknown. The expressive value of a word denotes the author's level of thinking depending on the situation in which he uses the words to express his thoughts. In this sense the word is chosen with a different approach for the communication on a friendly or intimate level from an approach used in a communication on the official level or in a relation between the individual and the public. All this affirms the word as a mean that is individually chosen and used for the expression of the speaker's ideas, attitudes and points of view in the communication process, which reveals the characteristics and the speaker's level in all the named aspects of the word value assessment. In the case of evaluation., of the word through the experience of the on-stage speech, that is, the words in the experience of the theatre art, the approach to the value assessment is contrary to the assessment carried out in an everyday, real experience. In the artistic language the words are already given, the sentences are formulated and all this is determined by the author's will and the act of creation. The actor is the interpreter of the author, his ideas along with the characters of the protagonists and the spirit of the action and, therefore, he must gradually master the word to the extent where it seems spontaneous from the point of view of the impressive and expressive categories. It also has to sound similar to the natural speech and its suggestive influence. With this counter-natural direction of the treatment of the given word it is important to reach the level of spontaneity of the expression to an almost documentary form in the overall verbal-scenic-mimic articulation. In this process the life and the art mesh and the art illustrates and defends the life.

Activities of Daily Living↗

Dwarfs in ancient Egypt.

Ancient Egypt was one of the most advanced and productive civilizations in antiquity, spanning 3000 years before the "Christian" era. Ancient Egyptians built colossal temples and magnificent tombs to honor their gods and religious leaders. Their hieroglyphic language, system of organization, and recording of events give contemporary researchers insights into their daily activities. Based on the record left by their art, the ancient Egyptians documented the presence of dwarfs in almost every facet of life. Due to the hot dry climate and natural and artificial mummification, Egypt is a major source of information on achondroplasia in the old world. The remains of dwarfs are abundant and include complete and partial skeletons. Dwarfs were employed as personal attendants, animal tenders, jewelers, and entertainers. Several high-ranking dwarfs especially from the Old Kingdom (2700-2190 BCE) achieved important status and had lavish burial places close to the pyramids. Their costly tombs in the royal cemeteries and the inscriptions on their statutes indicate their high-ranking position in Egyptian society and their close relation to the king. Some of them were Seneb, Pereniankh, Khnumhotpe, and Djeder. There were at least two dwarf gods, Ptah and Bes. The god Ptah was associated with regeneration and rejuvenation. The god Bes was a protector of sexuality, childbirth, women, and children. He was a favored deity particularly during the Greco-Roman period. His temple was recently excavated in the Baharia oasis in the middle of Egypt. The burial sites and artistic sources provide glimpses of the positions of dwarfs in daily life in ancient Egypt. Dwarfs were accepted in ancient Egypt; their recorded daily activities suggest assimilation into daily life, and their disorder was not shown as a physical handicap. Wisdom writings and moral teachings in ancient Egypt commanded respect for dwarfs and other individuals with disabilities.

Dwarfism↗

Tracking speech comprehension in space and time.

A fundamental challenge for the cognitive neuroscience of language is to capture the spatio-temporal patterns of brain activity that underlie critical functional components of the language comprehension process. We combine here psycholinguistic analysis, whole-head magnetoencephalography (MEG), the Mismatch Negativity (MMN) paradigm, and state-of-the-art source localization techniques (Equivalent Current Dipole and L1 Minimum-Norm Current Estimates) to locate the process of spoken word recognition at a specific moment in space and time. The magnetic MMN to words presented as rare "deviant stimuli" in an oddball paradigm among repetitive "standard" speech stimuli, peaked 100-150 ms after the information in the acoustic input, was sufficient for word recognition. The latency with which words were recognized corresponded to that of an MMN source in the left superior temporal cortex. There was a significant correlation (r = 0.7) of latency measures of word recognition in individual study participants with the latency of the activity peak of the superior temporal source. These results demonstrate a correspondence between the behaviorally determined recognition point for spoken words and the cortical activation in left posterior superior temporal areas. Both the MMN calculated in the classic manner, obtained by subtracting standard from deviant stimulus response recorded in the same experiment, and the identity MMN (iMMN), defined as the difference between the neuromagnetic responses to the same stimulus presented as standard and deviant stimulus, showed the same significant correlation with word recognition processes.

Adult↗

The Marc Dax (1770-1837)/Paul Broca (1824-1880) controversy over priority in science: left hemisphere specificity for seat of articulate language and for lesions that cause aphemia.

One of the most fascinating and frustrating issues in the priority of discovery in science is over just who, for the first time, went on record in the public forum, either orally at a conference or through a published communication, proclaiming that the faculty of articulate human speech was located in the left, not the right, cortical hemisphere. The disputed paper was purportedly written in 1836 by Marc Dax, who died subsequently in 1837. He was a physician in southern France in the city of Montpellier--far from the medical center of Paris. Little note was made of the presumed paper until the early and mid-1860s, when the issue of language localization in the human brain took on increased activity, as the clinico-pathological method of explanation continued to flourish in the "Art of Physick." Marc Dax's son, Gustave, happened to be studying medicine in Paris in the 1860s, and, as most of the neuroscientific and anthropological researchers, came to know of Broca's published work, which in 1861, agreed with phrenological theory that this faculty was, indeed, in the anterior lobes, but further claimed, de novo, that the region in the anterior lobe was more precisely focused at the foot of the 3rd frontal convolution in that lobe, still assuming with phrenological theory and the "Law of Symmetry" that the faculty was bilaterally located. It was not until 1865 that Broca clearly, non-hesitatingly, and unambiguously claimed that the faculty was in the left hemisphere. As it turned out, Gustave, six weeks before Broca's paper appeared, had published the paper he said his father had written in 1836. In 1863, in fact, Gustave had submitted his (Gustave's) long monograph on aphemia, integrating what he claimed to be his father's 1836 pronouncement along with his own data. He sent this communication to the French Academy of Sciences and to the French Academy of Medicine; he heard nothing back from either academy. After waiting two years, he managed to publish his material. Gustave's valiant move to promote his father's priority for one of the most significant conclusions in the history of the neurosciences is a lesson in frustration. Broca's attitude towards Gustave's case was disarmingly nonchalant; the issue deserves further historical inquiry.

Aphasia, Broca↗

What is conceptual research in psychoanalysis?

The development of psychoanalysis as a science and clinical practice has always relied heavily on various forms of conceptual research. Thus, conceptual research has clarified, formulated and reformulated psychoanalytic concepts permitting to better shape the findings emerging in the clinical setting. By enhancing clarity and explicitness in concept usage it has facilitated the integration of existing psychoanalytic thinking as well as the development of new ways of looking at clinical and extraclinical data. Moreover, it has offered conceptual bridges to neighbouring disciplines particularly interested in psychoanalysis, e.g. philosophy, sociology, aesthetics, history of art and literature, and more recently cognitive science/neuroscience. In the present phase of psychoanalytic pluralism, of worldwide scientific communication among psychoanalysts irrespective of language differences and furthermore of an intensifying dialogue with other disciplines, the relevance of conceptual research is steadily increasing. Yet, it still often seems insufficiently clear how conceptual research can be differentiated from clinical and empirical research in psychoanalysis. Therefore, the Subcommittee for Conceptual Research of the IPA presents some of its considerations on the similarities and the differences between various forms of clinical and extraclinical research, their specific aims, quality criteria and thus their specific chances as well as their specific limitations in this paper. Examples taken from six issues of the International Journal of Psychoanalysis in 2002-3 serve as illustrations for seven different subtypes of conceptual research.

Empiricism↗

[Bodies scorned: when medicine and caricature meet].

With the advent of the illustrated press, in 1840, the art of caricature initiated an interesting dialogue with historical painting and portraiture. The article shows dr. Oswaldo Cruz as target of this humorous language in the early twentieth century. Caricature -- a line that cries out -- recognizes the pain of its injured subject and, under an unwritten intersubjective pact, uses humor to release the violence of suffered aggression.

Brazil↗

[Rules for the writing of scientific papers with remarks on the art of composition and nomenclature].

Students and young scientists are often helpless when writing their first paper. The author has observed over a period of time that poor style, misuse of the German language and inappropriate dermatological terminology have crept in that should be eradicated. In this paper, an attempt is made to provide constructive advice on how to organize a manuscript and how to give it better form.

Dermatology↗