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The effect of heavy orthopedic forces on the sutures of the facial bones.

The effect of heavy continuous orthopedic forces was studied in three Saimiri Sciureus (squirrel) monkeys. Two additional monkeys served as controls. The maxillary sutures were investigated microscopically. In addition, the bone markers (tetracycline, Procion Red H-8 BS) served for quantitative evaluation under ultraviolet light. After two weeks slight remodeling activity could be observed. After one month a tremendous activity was found in the sutures. The width of the sutures was two to three times enlarged. The regular tissue pattern of the sutures had changed to a mixture of precollagen and collagen fibers running in all directions with plenty of active cells. In the ultraviolet light there is a take up of markers at the sutural margins. After three months of treatment though, the sutures showed a similar pattern. The three zones of the sutures began to form again; osteoblasts were attached to the sutural margins and reorganization was relatively complete.

Animals↗

Absent iris stroma, narrow body build and small facial bones: a new association or variant of SHORT syndrome?

We report four patients from two unrelated families with strikingly similar facial appearance, short stature, narrow body build and, in two of the patients, abnormalities of the iris stroma. The birth of an affected offspring suggests that this syndrome is likely to have autosomal dominant inheritance. The facial appearance and some of the features resemble the SHORT syndrome, the name being an acronym for Short stature, Hyperextensible joints, Ocular depression, Rieger anomaly and abnormalities of the Teeth. The relationship of the syndrome to the SHORT syndrome is discussed.

Abnormalities, Multiple↗