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At least 325 records · Page 18Linked to original sources
PubMed1976

UV laser scanning and fluorescence monitoring of analytical ultracentrifugation with an on-line computer system.

A new optical system for the analytical ultracentrifuge is described, which permits sedimentation to be monitored by fluorescence. The optical system is based on a laser light source, which is focused to a narrow (50 micron) beam. The radical scanning of the beam provides information on the distribution of fluorescing material with distance in the centrifuge cell. Data collection and processing are performed in conjunction with an on-line computer system which sorts incoming fluorescence pulses according to rotor hole and cell sector, averages families of pulses to improve signal to noise ratios and fits the data (in the experiments reported here) to equations to determine sedimentation coefficients. Initial experiments with the system have been performed with bovine serum albumin and indicate that sedimentation can be readily monitored by fluorescence with solutions at concentrations as low as 20 micrograms per ml, with excitation at 257 nm. At these concentrations, the optical density is only in the 0.01 range, too low for experiments with absorption-scanner optical system. Even lower concentrations can be used when fluorescent labels are used with excitation in the visible region of the spectrum. The preliminary studies indicate that fluorescence monitoring of sedimentation will substantially enhance the range of experimental possibilities in ultracentrifugation by improving both the sensitivity of measurements and the discrimination between sedimenting species on the basis of their fluorescence characteristics.

Computers↗
PubMed1996

Computer system failure: planning disaster recovery.

A disaster recovery plan (DRP) defines the scope of restoration, establishes responsibilities and lists specific actions to be taken after the disaster. Although not actually involved in a DRP or computer systems, nurse managers must understand the steps involved and identify and communicate nursing's requirements.

Disaster Planning↗
PubMed1990

[Computer systems at a Center for sexually transmitted diseases. Considerations after 1 year's activities].

In January 1989, the Center for Sexually Transmitted Diseases (STD) of Galliera Hospital-Genoa was equipped with a network of 5 Personal Computers connected by a Token Ring to another Personal Computer which is the "server" unit. The Authors report their experiences in the use of the computer system and examine the advantages of networking in the management of a Center for Sexually Transmitted Disease.

Hospitals, Special↗
PubMed1982

An on-line computer system for monitoring respiratory and cardiac functions of patients.

A computer-based noninvasive and continuous patient monitoring system for breath-by-breath assessment of cardiorespiratory functions was developed. Transthoracic impedance changes caused by respiratory and cardiac activities were measured with separate impedance plethysmographs of different frequencies. A mini-computer system calculated on-line eight respiratory parameters (VT, f, VE, PETO2, PETCO2, VO2, VCO2, and R) in cooperation with expired gas analysis data from a mass-spectrometer, and three cardiac parameters (SV, HR and Q). These parameters were displayed simultaneously at the end of each breath. In order to improve the signal-to-noise ratio of the impedance cardiogram to a level allowing computer determination, an ensemble averaging technique was utilized. The computer-derived cardiorespiratory parameters obtained during voluntary hyperventilation and a passive tilt demonstrated reasonable changes.

Carbon Dioxide↗
PubMed1998

Black Sea TeleDiab: diabetes computer system with communication technology for Black Sea region.

BlackSea TeleDiab (BSTD) is a multidisciplinary research project whose aim is to promote the exchange of healthcare information between clinicians and scientists in countries of the Black Sea area to provide a means by which the care of patients with diabetes may be enhanced. The project is built on an existing organizational framework provided by the WHO Diabcare Quality Network (Q-Net) and the Black Sea Diab Action Project. The aim is to develop a standardized software package (in the national languages of the CCE/NIS Black Sea partners) for the storage and transfer of medical information and healthcare data between participating institutions. It will utilize a standard format for medical records based on the Good European Health Record (GEHR), a project within the Advanced Informatics in Medicine (AIM) program, which aims to develop and propagate a common architecture for computerized health records across Europe that can be used across clinical domains, countries, and computer systems.

Computer Communication Networks↗
PubMed1977

Camera-computer systems for rapid dynamic imaging studies.

The extraction of valuable diagnostic information from rapid, dynamic studies performed on a gamma camera requires that the data be recorded for latter analysis. If these data are to be available rapidly and if quantitative analysis is to be performed, it is imperative that a computer be used in conjuction with the gamma camera. This review describes the more important features of a nuclear medicine computer system both from the point of view of hardware and software. The various aspects that cause some limitations to be imposed on the capability of the system in order to carry out fast, dynamic studies are described and some possible solutions are suggested.

Analog-Digital Conversion↗
PubMed1989

[Analysis of the retinal blood flow by means of the blue field entoptic phenomenon and simulation of entoptic leucocytes with a personal-computer system].

A method was developed for determining the velocity of macular blood flow. Leukocytes flowing in the macular capillaries can be recognized when the retina is illuminated with blue light (blue field entoptic phenomenon). The motion of the leukocytes was simulated by a personal-computer system. The velocity of the macular blood flow was determined by adjusting the motion of the simulated corpuscles to that of the entoptically recognized leukocytes. The velocity of the maximum, minimum and mean macular blood flow were measured as 1.25 +/- 0.25, 0.42 +/- 0.11 and 0.80 +/- 0.14 mm/sec respectively. The mean coefficients of variation were 6.7%, 13.4% and 5.7% for each velocity. This method may be useful for the analysis of the retinal circulation and the diagnosis of retinal diseases.

Adult↗
PubMed1983

Morphometric synaptology of a whole neuron profile using a semiautomatic interactive computer system.

We propose a new method of dealing with morphometric synaptology that processes all synapses and boutons around the HRP marked neuron on a large composite electron micrograph, rather than a qualitative or a piecemeal quantitative study of a particular synapse and/or bouton that is not positioned on the surface of the neuron. This approach requires the development of both neuroanatomical procedures, by which a specific whole neuronal profile is identified, and valuable specialized tools, which support the collection and analysis of a great volume of morphometric data from composite electron micrographs, in order to reduce the burden of the morphologist. The present report is also concerned with the total and reliable semi-automatic interactive computer system for gathering and analyzing morphometric data that has been under development in our laboratory. A morphologist performs the pattern recognition portion by using a large-sized tablet digitizer and a menu-sheet command, and the system registers the various morphometric values of many different neurons and performs statistical analysis. Some examples of morphometric measurements and analysis show the usefulness and efficiency of the proposed system and method.

Animals↗
PubMed2002

[Assessment of operating theatre procedures and quality of perioperative anaesthesia using a computer system for collecting anaesthesiological data].

BACKGROUND: In order to manage the operating theatre and guarantee constant improvement in the quality of procedures, it is indispensable to be able to have available a computerised workstation to enable the team to collect data and analyse them. METHODS: We used our anaesthesia department's computer workstation to retrospectively analyse operating sessions over a 16 month period during which organisational adjustments were made to optimise patient turnover and maximise the utilisation of operating theatres. Meantime we studied and compared the trend in anaesthesiological quality through the use of certain structural, process and outcome indicators. RESULTS: During the period under study an improvement was noted in the efficiency of operating theatre procedures (reduction in entry time of the first patient into the theatre, time between one case and the next and subutilisation of the operating theatre, p<0.05). As regards data on the quality of anaesthesiological assistance to the patient, no significant differences were noted when comparing the four periods examined. CONCLUSIONS: To make the operating complex work more efficiently, it is necessary to have available a computer system that makes it possible to continuously monitor theatre operation. The improvement initiatives undertaken led to a more effective utilisation of the operating theatre but did not produce a significant increase in productivity. In spite of the increased work load, analysis of the trend in quality indicators as regards anaesthesiological procedures did not reveal any modification.

Anesthesia↗