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At least 325 records · Page 18Linked to original sources
PubMed1983

[Treatment of tuberculosis before the introduction of chemotherapy].

20 years before the detection of the tubercle bacillus by Robert Koch Brehmer and Dettweiler have created the fundamentals of tuberculosis therapy. The rest-cure in the open air initiated by them and the system of sanatorium treatment resulting from it have formed the management of tuberculosis all over the world for nearly 100 years. Even collapse therapy in the heroic phase of tuberculosis treatment has remained only a supplement to conservative therapy. In the centre of the scientific discussions, substantially influenced also by the "Wiener Schule", there were the problems of the first manifestations of tuberculous disease its early detection, giving the best chances of cure at those times; there was the knowledge that the cavity was of crucial significance for the fate of the tuberculous patient; in consequence thoracic collapse surgery was developed.

Collapse Therapy↗
PubMed1998

[Surgery of late complications of previous active treatment of lung tuberculosis with extrapleural plombage].

Between January 1984 and February 1997 10 patients with late complications of a former active collapse therapy were operated. In case of our patients between 1943 and 1960 the collaps therapy was carried out with the extrapleural instillation of plombs for therapy of pulmonary tuberculosis. At present main complications were infections of plombs with pleurobronchial and pleurocutaneus fistulas and perforation of plombs. By all patients both extirpation and pleurectomy were necessary. In case of 5 patients additionally lung resection was required, in case of 3 patients a thoracoplasty and by 1 patient a myoplasty. Although there are considerable destructions of lung parenchym in a part the results of long-term follow up are satisfactory: 6 patients are so far without complaints; only 1 patient died 10 years postoperative. Prerequisite for a successful therapy are the knowledge of the surgical methods of the collaps area, the used materials, the pathomorphological pulmonary changes and the good cooperation between pneumologists and thoracic surgeons.

Adult↗
PubMed1998

[Current indications for resection of tuberculoid lung changes--relics of the pre-chemotherapy era?].

The spectrum of indications for elective resection of pulmonary tuberculosis was considerably reduced by clinical evaluation of the effective antituberculous chemotherapy and is limited only to a few pathomorphological processes and clinical situations today. The same estimation is valid in case of nontuberculous mycobacteriosis with clinical importance. The combined therapy with new macrolid antibiotics, quinoloses and Rifampicin-derivatives current enlarged the options of conservative therapy. Thus the surgery of pulmonary tuberculosis are rare operations and are essentially limited to the therapy of late complications of a former collapse therapy, of destroyed lungs and bronchiectasis with recurrent infect exacerbations and life threatening or massive recurrent haemoptysis.

Anti-Bacterial Agents↗
PubMed1986

Pulmonary tuberculosis: contributions of radiology in diagnosis and treatment.

This review records the important place that radiologic examinations have had in the diagnosis and treatment of pulmonary tuberculosis in the past nine decades. Very soon after the discovery of x-rays it became apparent that chest roentgenograms would be a help in identifying pulmonary lesions. As the quality of the examinations improved, the benefits became significantly better. Earlier lesions were diagnosed. Follow-up studies after medical or surgical treatment were increasingly helpful. Newly developed techniques allowed demonstration of extrapulmonary complications. Radiologic monitoring of collapse therapy played a critical role in the successes achieved. Even after the medical conquest of active tuberculous lesions by drug therapy, identification of new lesions and follow-up of treated patients remains a significant role for radiology. Control of this once fatal and widely feared disease depends on continued early recognition and appropriate treatment.

Collapse Therapy↗
PubMed1992

Fatal mediastinal compression as a late complication of surgical plombage.

Surgical plombage was used as a form of collapse therapy for pulmonary tuberculosis before the advent of reliable chemotherapy. A patient developed stridor, recurrent laryngeal nerve paralysis, and obstruction of the superior vena cava and eventually died as a result of haemorrhage into a large intrathoracic cyst, secondary to a polystan pack inserted 38 years previously.

Aged↗
PubMed1997

[Surgery of thoracic and pulmonary tuberculosis and the sequelae of its treatment in adults].

Surgery for tuberculosis was the starting point for thoracic and cardiovascular surgery in the modern day, but its place was more and more restricted to the treatment of the disease. Excisions (lobectomies, pneumonectomies, segmentestomies) currently represent the majority of operations, after this come operations on the pleura (decortication) and rarely those on the thoracic wall (thoracoplasty, parietectomy). The indications for excision are principally encountered with disease of the parenchyma itself: progressive disease under treatment or with resistant tubercle bacilli, sequelae of parenchymal complications (infections, aspergilloma or haemoptysis) and certain forms of atypical mycobacteria, and also a small but significant group in which excisions are aimed at diagnosis. Sometimes excisions are associated by necessity with decortication for pleural disease which may or may not have originally been intended for the underlying parenchyma or the lesions may be the sequelae of previous complications of treatment such as collapse therapy. Occasionally surgery is indicated in the treatment of lymph node masses in the mediastinum which have not responded to antituberculous therapy and during the treatment bronchial complications have evolved or there have been other sequelae. As for the indications for surgery of the thoracic wall such as thoracoplasty, they appear more than ever obsolete and even if they are still used in certain complications of surgery, they have apart from a few exceptions, lost their original therapeutic role in tuberculosis. However, currently there is a recrudescence of tuberculosis favoured by certain socio-economic situations and strengthened by the appearance of TB cultures which are more and more resistant. The surgery of tuberculosis in its oldest forms (thoracoplasty and removal of cavities) can no longer be said to be the surgery of the past. They proved in the old days that they could cure. Surgery has once more its place in the therapeutic arsenal of new forms of the disease and indirectly in limiting the risk of spread it has a role to play in prevention.

Adult↗
PubMed1956

Basal plombage.

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Collapse Therapy↗