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PubMed1989

[Effect of work in hot shops at the coke-processing plant on the liver and gastrointestinal tract].

253 cooking plant workers employed for 5 years were examined. 207 of them were exposed to very high concentrations of BaP and tar substances, as well as to benzene, its homologues and CO at concentrations not exceeding MAC values. In 20% of the examined workers of the baking ovens department exposed to very high BaP concentrations an abnormal activity of marker enzymes was demonstrated, while in 63% of workers C-14 aminopyrine test was pathologic. These facts indicate that hepatocyte microsomal injury may be affected by toxic effects of BaP. The stool occult blood test was positive in 4% of subjects, which resulted from some non-malignant diseases of the digestive system.

Adult↗
PubMedDate not supplied

[Various non-specific immunity proteins in the blood serum of workers in the coke-processing industry].

The concentrations of certain proteins related to non-specific immunity were determined in the serum of cokery workers and in a matched control group. No changes were found in the concentrations of the main proteins of the properdin system, that is properdin and third fraction of complement. However, the level of transferrin was higher in cokery workers. It seems that the harmful effects of the working environment were not changing the function of the properdin system. Raised transferrin level seems to be only a biochemical trace of exposure without essential importance.

Adult↗