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DISI Deformity and Post-Operative Symptoms of Scaphoid Non-Union.

The correlation between the residual dorsal intercalated segmental instability (DISI) deformity and symptoms of the wrist was investigated in 20 patients with healed scaphoid non-union who had open reduction and bone grafting. In seven patients, inlay corticocancellous bone grafting (modified Russe procedure) was performed. In four of the seven patients, an additional Herbert bone screw was used for internal fixation. The remaining 13 patients were treated with open reduction, anterior bone grafting, and internal fixation with Herbert bone screw. Average duration of follow-up period after operation was 20 months (range, 6 to 57 months). The average extension-flexion arc of the injured wrists was 129 degrees, which was 31 degrees less than that of the uninjured wrists. The average grip strength of the injured wrists was 89% of that of the uninjured wrist. Before the operation, all 20 patients were symptomatic and complained of wrist pains. Post-operatively, three patients experienced mild pains and only one complained of moderate wrist pains. Post-operative radiolunate angle ranged from 0 degrees to 34 degrees (average 10 degrees ). DISI deformity remained uncorrected in eight patients. Post-operative symptoms were compared amongst the eight patients who had DISI deformity and 12 patients who had no deformity. There was no significant difference in range of motion, grip strength, and incidence of pain between these two groups of patients. The presence of DISI deformity after bone grafting for a symptomatic scaphoid non-union was not predictive of post-operative symptoms of the wrist.

Journal Article↗

Analysis of cementless implants using interface nonlinear friction--experimental and finite element studies.

Measured interface nonlinear friction properties are used to develop models to study the short-term fixation response of smooth- and porous-surfaced posts, bone screws, and plates fixed with and without posts/screws. Experimental studies are carried out to validate the model predictions and identify the relative role of posts and screws in fixation of a plate on a polyurethane block under symmetric/eccentric axial compression loads. The idealized Coulomb's friction is also used for the sake of comparison. The incorporation of measured nonlinear, rather than the idealized Coulomb, friction is essential to compute realistic results. For plate fixation, the experimental and finite element results show that the screw fixation yields the stiffest response followed by the smooth- and then porous-coated post fixation. For example, under 1000 N eccentric axial compression, the edge of the plate opposite the loaded edge is measured to lift by 1147 +/- 72, 244 +/- 38, or 112 +/- 28 microns, respectively, for the cases with no fixation, with smooth-surfaced posts, or with screws. The corresponding models predict, respectively, values of 1538, 347, or 259 microns and also 556 microns for the plate fixed with porous coated posts. The satisfactory agreement between numerical and experimental results confirms the importance of proper interface modelling for the analysis of posts, screws, and complex fixation systems. This becomes further evident when considering cementless implants in which the bone-implant interface exhibits relatively large displacements as the maximum resistance force is reached. The developed models can be used to investigate the post-operative short-term stability of various cementless implant designs.

Bone Cements↗

Plating of metacarpal fractures: unicortical or bicortical screws?

Mid-shaft transverse osteotomies were performed in 18 cadaveric metacarpals and randomly divided into two groups. Using dorsally applied plates for repair, one group was secured using 6mm unicortical screws, while bicortical screws were used in the second group. The metacarpals were tested to failure with a four-point bending protocol using a servo-hydraulic testing machine and a 1kN load cell. The mean load to failure was 596N (SD=142) for the unicortical and 541N (SD=171) for the bicortical group. The stiffness was 333N/mm (SD=116) for the unicortical and 458N/mm (SD=158) for the bicortical group. Both load to failure and stiffness were not statistically significant between the two groups. Failure occurred by fracture at the screw-bone interface in all specimens: no screw pull-out was observed. No biomechanical advantage was found when using bicortical screws in metacarpal fracture plating.

Aged↗

A citric acid-based hydroxyapatite composite for orthopedic implants.

We describe a novel approach to process bioceramic microparticles and poly(diol citrates) into bioceramic-elastomer composites for potential use in orthopedic surgery. The composite consists of the biodegradable elastomer poly(1,8-octanediol-citrate) (POC) and the bioceramic hydroxyapatite (HA). The objective of this work was to characterize POC-HA composites and assess the feasibility of fabricating tissue fixation devices using machining and molding techniques. The mechanical properties of POC-HA composites with HA (40, 50, 60, 65wt.%) were within the range of values reported for tissue fixation devices (for POC-HA 65wt.%, S(b)=41.4+/-3.1, E(b)=501.7+/-40.3, S(c)=74.6+/-9.0, E(c)=448.8+/-27.0, S(t)=9.7+/-2.3, E(t)=334.8+/-73.5, S(s)=27.7+/-2.4, T(s)=27.3+/-4.9, all values in MPa). At 20 weeks, the weight loss of POC-HA composites ranged between 8 and 12wt.%, with 65wt.% HA composites degrading the slowest. Exposure of POC-HA to simulated body fluid resulted in extensive mineralization in the form of calcium phosphate with Ca/P of 1.5-1.7 similar to bone. POC-HA supported osteoblast adhesion in vitro and histology results from POC-HA samples that were implanted in rabbit knees for 6 weeks suggest that the composite is biocompatible. Synthesis of POC-HA is easy and inexpensive, does not involve harsh solvents or initiators, and the mechanical properties of POC-HA with 65wt.% HA are suitable for the fabrication of potentially osteoconductive bone screws.

Animals↗

Revision total knee arthroplasty.

Revision total knee arthroplasty can be very successful if careful preoperative planning has been carried out and the surgeon is equipped to handle potential problems encountered with restoration of static alignment, stability, and deficient bone stock. Special femoral and tibial component extractors are indispensable tools. A high-speed burr is helpful. Posterior cruciate ligament-preserving prostheses often can be used, but prostheses with extra degrees of constraint must be available. Long-stemmed components for both the femoral and tibial sides should be available. Access to a bone bank to obtain allogeneic bone for grafting is essential. The surgeon must be familiar with techniques other than bone grafting for restoration of deficient stock, such as the use of bone screws and cement, custom-augmented components, and metal wedge spacers.

Arthroplasty↗

Restoration of pedicle screw fixation with an in situ setting calcium phosphate cement.

STUDY DESIGN: Pedicle screws were pulled out of human cadaveric vertebrae before and after augmentation with polymethylmethacrylate or in situ-setting calcium phosphate cement. The fixation strength of screws augmented with calcium phosphate cement was compared with that of screws augmented with polymethylmethacrylate. OBJECTIVES: To determine whether a new in situ-setting calcium phosphate cement might be suitable for augmenting the fixation of pedicle screws. The principle objective was to compare the pull-out resistance of screws augmented with calcium phosphate cement with the pull-out behavior of screws augmented with polymethylmethacrylate. Polymethylmethacrylate augmentation was chosen as the standard because of its current clinical use. Five types of screws were tested to determine whether screw design had an effect on the efficacy of augmentation. SUMMARY OF BACKGROUND DATA: Although many factors affect the pull-out resistance of pedicle screws, a key determinant of their performance is the strength of their attachment to the spine. In elderly, osteopenic patients, the screw-bone interface is especially at risk for stripping during insertion or pull-out after surgery. In these patients, polymethylmethacrylate has been used to augment pedicle screw fixation, although its use is not without risk. In situ-setting calcium phosphate cements may provide an alternative to polymethylmethacrylate in this application. Like polymethylmethacrylate, calcium phosphate cements can be injected into the prepared screw hole. They have the added advantage of being resorbed and replaced during healing and normal bone remodeling. METHODS: Thirty human lower lumbar vertebrae (L3-L5) were implanted bilaterally with one of five types of pedicle screws (n = 6 for each screw type). The screws were pulled out 3.0 mm at 0.25 mm/sec with a servohydraulic materials testing machine. The 3.0-mm pull-out distance, which was slightly longer than one thread pitch, was designed to strip the screw-bone interface but to leave the pedicle otherwise intact. After the initial testing, the screws in each vertebrae were removed, and the screw tracks were filled with 2.0 cc of polymethylmethacrylate (one side) or calcium phosphate cement (contralateral side). After augmentation, the screws were reinserted, and the cements were allowed to harden for 24 hours. Postaugmentation testing followed the protocols for preaugmentation testing, and the pull-out resistance of screws augmented with calcium phosphate cement was compared with the pull-out resistance of screws augmented with polymethylmethacrylate. RESULTS: Mechanically, calcium phosphate cement compared favorably with polymethylmethacrylate for augmenting pedicle screws. Both restored the strength of the screw-bone interface: across all screw types, the average increase in pull-out strength was 147% with polymethylmethacrylate augmentation and 102% with calcium phosphate cement. There were no significant differences because of screw type with either type of augmentation. CONCLUSIONS: The in situ-setting calcium phosphate cement investigated in this study compared favorably with polymethylmethacrylate in a single-cycle, pull-out test of augmented pedicle screws in senile trabecular bone. With further evaluation, this cement may offer an alternative to polymethylmethacrylate for the enhancement of pedicle screw fixation clinically.

Bone Cements↗

Clinical and radiographic results of ACL reconstruction: a 5- to 7-year follow-up study of outside-in versus inside-out reconstruction techniques.

This study compared the clinical outcome of anterior cruciate ligament (ACL) reconstruction between the inside-out and the outside-in techniques and assessed radiographically whether surgical technique affects the position and direction of the bone tunnels. A patellar tendon ACL reconstruction was performed in 141 patients with inside-out (group I, n = 78) and outside-in technique (group II, n = 63). Clinical results were evaluated using the International Knee Documentation Committee (IKDC) form; radiographic study was performed in anteroposterior, lateral, and notch views. Overall results in group I were normal in 23% of cases, nearly normal in 55%, and abnormal in 22%; in group II there were normal results in 19% of cases, nearly normal in 57%, abnormal in 19%, and severely abnormal in 5%. Radiographic examination identified important differences between the two groups. The main differences between the two surgical techniques were related to the positioning of the femoral tunnel. With the inside-out technique the femoral tunnel was significantly more vertical, both in the frontal and the sagittal planes. Moreover, the femoral tunnel was higher when drilled from the inside, but the difference between the two techniques was not statistically significant. The differences found between the two techniques regarding the tibial tunnel were not significant, although in the inside-out group the tibial tunnel seemed slightly more lateral, vertical, and posterior. Moreover, we observed a greater risk of bone-screw divergence on the femur in the inside-out group. This divergence was greatest in the sagittal plane. However, we observed no effect of this bone-screw divergence on the stability of the knee at follow-up.

Adolescent↗

Wu's bunionectomy: a clinical analysis of 150 personal cases.

The author discusses his modification of the Mitchell distal metatarsal osteotomy/bunionectomy, in a study of 150 cases. He advocates a distal transverse first metatarsal osteotomy, with fixation using Herbert bone screws. Stepwise description of the surgical technique with evaluation of cases including complications is provided.

Bone Screws↗

Treatment of intraarticular fractures with modified herbert screws (analysis of 69 cases).

Sixty-nine patients with intraarticular fractures were treated with modified Herbert screws between August 1988 and December 1994. They were followed for an average of 20 months (range, 6 months to 4 years). The final results were assessed in terms of patient satisfaction, clinical examination, and radiographic findings. The success rate was 89.8% (62/69). There were no serious complications. The authors believe the advantages of the modified Herbert screw over the Arbeitsgemeinschaft für osteosynthesefrogen cancellous bone screw are many. The modified Herbert screw provides rigid internal fixation with strong purchase on the bone, so that additional immobilization in plaster is seldom required. It can be inserted through articular cartilage and appropriately buried beneath the articular surface. It is not necessary to remove the screw after bone union. This type of fixation can be widely used in the clinical setting.

Adolescent↗

Polyacetal rod fixation of fractures in osteoporotic bone. A preliminary report.

Intramedullary rods manufactured from polyacetal were used to fix diaphyseal fractures in osteoporotic bone. They are pliable and can be introduced without further damage to such bone. Their low elastic modulus induces abundant callus. They can be locked with cortical bone screws without the need of jigs or radiographic control. Nine femoral and five tibial fractures were fixed in 10 patients, all with osteoporosis; 13 united primarily; one required bone grafting. No implant broke; however, no ambulant patient weighed more than 75 kg. The rods offer a promising treatment for diaphyseal fractures in osteoporotic bone.

Acetals↗

Dorsal tarsal instability in three racing greyhounds.

Rupture of the dorsal ligaments of the tarsus in the greyhound is a rare racing injury. This case report describes dorsal tarsal instability in three greyhounds. A stumble and somersault were observed in two cases and were thought to have caused the injury. Previous reports advocate partial intertarsal arthrodesis as the preferred treatment for dorsal instability of the proximal intertarsal joint, but not all dogs returned to successful racing. In these three cases, stability was restored by the insertion of a wire tension band anchored to two bone screws, allowing the development of periarticular fibrosis. The dogs raced again with no loss of form.

Animals↗

Complications with intermaxillary fixation screws in the management of fractured mandibles.

A dedicated bicortical bone screw for temporary intraoperative intermaxillary fixation (IMF) during open reduction and fixation of mandibular fractures offers many benefits to surgeons and patients. We have used this system for 2 years and confirm the benefits over traditional methods of intermaxillary fixation. However, complications can arise. One hundred and twenty-two patients with mandibular fractures had IMF screws of which five (4%) developed complications intraoperatively and postoperatively. Complications included fracture of the screws on insertion, iatrogenic damage to teeth causing loss and bony sequestra around the area of screw placement.

Adult↗

Comparison of "inside-out" and "outside-in" interference screw fixation for anterior cruciate ligament surgery in a bovine knee.

Despite numerous advances in graft fixation with anterior cruciate ligament (ACL) reconstruction, few studies have compared the fixation strength of interference screws placed "outside-in" and from "inside-out" techniques. To compare techniques, a bovine model was designed to fail at the femoral tunnel bone-screw interface. Twenty-four fresh bovine knees were stripped of all soft tissues except the ACL. The native ACL was loaded the failure at a strain rate of 50 cm/min with the knee flexed 45 degrees. One standardized femoral tunnel was created on all specimens. A 3/32-inch guide pin was drilled into the center of the ACL femoral origin and overreamed with an 11-mm reamer from inside-out until the lateral cortex was reamed. Consistently sized patellar bone blocks were created (8 x 5 x 25 mm) with an 8-mm tendon width. The bone blocks were randomized to an "inside-out" (group 1) and "outside-in" (group 2) technique. Bone blocks were secured with a 7 x 25 interference screw. Specimens were mounted with the femoral tunnel and bone block aligned parallel to the tensile force and strained to failure at 50 cm/min. Failure of the native bovine ACL occurred at a mean of 2,304 N (SD +/- 472 N; n = 24). The mode of failure for group 1 was 9 of 13 at the bone-screw interface and 4 of 13 interligamentous failures. The mode of failure for group 2 was 7 of 11 at the bone-screw interface, 3 of 11 interligamentous, and 1 bone block failure. The mean load to failure for group 1 was 1,151 N (SD +/- 320 N, n = 13) including the four ligamentous failures and 1,143 N (SD +/- 306 N, n = 9) excluding the ligamentous failures. The mean load to failure for group 2 was 1,017 N (SD +/- 262 N, n = 11), including all specimens and 843 N (SD +/- 262 N, n = 7) excluding the interligamentous and bone block failure specimens. The "inside-out" technique averaged 100 N greater fixation strength than the "outside-in" technique. Statistical analysis using two-sample Student's t-test showed no statistically significant differences between group 1 and group 2. Both techniques demonstrate comparable maximum load to failure in a bovine model tested at 50 cm/min.

Animals↗

Peri-implant tissue reaction in bone irradiated the fifth day after implantation in rabbits: histologic and histomorphometric measurements.

To evaluate tissue reaction to cobalt 60 irradiation around implant materials used in maxillofacial surgery, 2.0-mm titanium alloy bone screws and 2.0-mm cylindrical solid hydroxyapatite implants were placed in mandibular bone of rabbits and irradiated with a single 15-Gy dose on the fifth postoperative day. Tissue reaction around the implants was examined histologically and histomorphometrically at 7, 14, 28 and 56 days after irradiation. Mature bone was relatively radioresistant, but newly formed bone around both implants was damaged by irradiation in several places. After irradiation, the beginning of bone formation was delayed and the amount of new bone formed was less. Bone-implant contact measured histomorphometrically was less in the irradiated group than in the nonirradiated group. All titanium alloy screws showed bone contact, but two of eight hydroxyapatite implants failed after irradiation, probably the result of loss of primary stability of the cylindrical implants caused by radiation damage to newly formed bone.

Alloys↗

Groningen temporomandibular joint prosthesis. Development and first clinical application.

Patients with a severely degenerated temporomandibular joint (TMJ) may benefit from an alloplastic TMJ replacement. The aim of the study was to develop a safe and properly functioning TMJ prosthesis. The design was based on imitation of anterior condylar translation by an inferiorly located centre of rotation, unrestricted mandibular movements by a double articulation, correct fit to the skull by a self-adjusting skull part consisting of two connected parts, and stable fixation by bone screws that are rigidly connected to the prosthesis parts. The prosthesis consists of a titanium skull part with ceramic inlay, a titanium mandibular part with a ceramic spherical head, and an intervening polyethylene disc. Titanium-alloy bone screws are used for fixation. All parts are available in a number of different shapes. In vitro laboratory and in vivo animal tests showed a low wear rate, the possibility of a close fit to the skull, a stable fixation, sufficient mechanical strength, appropriate choice of materials and proper functioning. Thereafter the step to first patient application was made. First patient application was carried out without adverse events. In conclusion, the presented TMJ prosthesis passed the pre-clinical tests and has progressed to clinical application. The fit to the skull, the expected lifetime of the device and the reliability of the implantation procedure require further evaluation in well-designed clinical trials.

Adult↗

Stripping torque as a predictor of successful internal fracture fixation.

BACKGROUND: Internal fixation of fractures using plates and screws is a common method of treatment. Occasionally the internal fixation fails prior to fracture healing. This often requires revision surgery. Determining the force that internal fixation needs to withstand postoperatively would enable this force to be applied intraoperatively as a test to predict successful fixation. The purpose of the present paper was to determine the minimum stripping torque needed to predict successful internal fixation strength. METHODS: The pull-out strength and stripping torque relationships of 4.5-mm cortical bone screws in Sawbones polyurethane foam were determined. Screw forces were directly measured using an LCM load cell washer on a model intertrochanteric neck of femur fracture fixed with 135 degrees 4-hole pin and plate loaded to single leg stance conditions. Additionally a 135 degrees 4-hole pin and plate was mounted on foam blocks and loaded until failure of the shaft screws from the foam occurred. Predicted stripping torque/yield load was determined. RESULTS: Pull-out strength and stripping torque of 4.5-mm cortical bone screws in polyurethane foam have a high degree of linear correlation R(2) = 0.95. Direct measurement of shaft screw forces at single leg stance conditions were 585-686 N. This correlated with a stripping torque of 0.9 Nm. Load to yield testing at single leg stance conditions corresponded to a stripping torque of 1.8 Nm. CONCLUSION: Withstanding 0.9-1.8 Nm of torque during insertion of the femoral shaft screws of a 135 degrees 4-hole pin and plate predicts that the construct will successfully withstand single leg stance.

Bone Nails↗

Comparison of the holding power of 3.5-mm cortical versus 4.0-mm cancellous orthopedic screws in the pelvis of immature dogs (cadavers).

A 3.5-mm cortical orthopedic screw was compared with a 4.0-mm cancellous screw for maximal load to failure in the pelvis of immature dogs. The pelvis from young cadavers (7 to 13 months old) was divided into hemipelves and used for testing of the 2 screw types. Two sites in each hemipelvis were used, mid-shaft of the ilium and mid-sacrum, including the wing of the ilium. The screws were extracted, and maximal load to failure and mode of failure were recorded. Maximal load to failure per millimeter of engaged thread was calculated. In either pelvic site, the 4.0-mm cancellous screw required a significantly (P < 0.05) higher pullout force per millimeter of engaged screw threads than did the 3.5-mm cortical bone screw.

Animals↗

Simple invasive fixation device for fractionated stereotactic LINAC based radiotherapy.

BACKGROUND: The aim of this study was to develop a relocatable fixation device for linear accelerator (LINAC) based fractionated stereotactic radiotherapy. METHOD: The device consists of a CT- and MRI-compatible stereotactic frame, monocortical titan bone screws, four frame-posts with a lock for the fixation pins and a modified head clamp with additional arms that allows the exact and rigid placement of the frame in the desired final position prior to the final placement of the bone screws. By simply disconnecting the lock from the posts, the frame can be dismounted after treatment planning and after each treatment session. The accuracy of reposition was assessed prospectively, using phantom studies and also by comparison of isocenter movements during fractionated radiotherapy in 10 patients with an intracranial lesion. FINDINGS: No adverse events were seen after the surgical procedure and the screws were well tolerated throughout the course of treatment. The mean isocenter shifts observed during phantom reposition studies were x=0.05 mm, y=-0.32 mm, z=0.18 mm and the mean isocenter shifts during fractionated treatment were x=0.67 mm, y=0.65 mm, z=0.44 mm. INTERPRETATION: This new fixation device provides excellent accuracy of reposition during stereotactic radiotherapy. It appears superior to non-invasive, mask fixation techniques. Safety margins as small as 1-1.5 mm may therefore be sufficient for this method of stereotactic radiotherapy.

Adult↗