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The clinical value of percutaneous transluminal angioscopy. Angioscopical findings in primary vascular diagnosis and in interventional radiology.

Since the introduction of ultrathin angioendoscopes into clinical application conventional or digital angiography have been controlled by using the same approach like in angiography. In dogs and angiography patients this new angioscopic method for arteries without surgical intervention has been developed. The approach is transfemoral. Endoscopy is combined with angiography, percutaneous transluminal angioplasty (PTA), thrombolysis, thrombus extraction and a new kind of stents and their application. An ultrathin endoscope with an outer diameter of 1.6 mm and working channel of 0.35 mm is used. Guide wires, contrast media and drugs for local thrombolysis can be applied through this channel. The endoscope is placed into the region of interest under fluoroscopic control and view is obtained by using 0.9% NaCl for decreasing blood flow. Endoscopy is documented by video or by a high-speed camera. It was possible to demonstrate the proceedings of dilatation, recanalization, local lysis, stent-application and thrombus-extraction.

Constriction, Pathologic↗

[Percutaneous angioscopy. Report of initial experiences with PTA and local lysis under angioscopic conditions].

In dogs and 11 patients a new endoscopic method for arteries has been developed. The approach is transfemoral, and endoscopy is combined with angiography, percutaneous transluminal angioplasty (PTA), and local lysis. An ultrathin endoscope with a diameter of 2.4 mm is used, which also provides a working channel with a diameter of 0.4 mm. Guide wires, contrast media, and drugs for local lysis can be inserted through this channel. Under fluoroscopic control, the endoscope is placed in the region of interest, followed by a special method for decreasing blood flow. Endoscopy is documented by video or by a high-speed camera. No complications have occurred. In all patients, it was possible to demonstrate the results of dilatation, recanalization, or local lysis before and after the interventional procedure.

Angioplasty, Balloon↗

Clinical application of percutaneous transluminal angioscopy. Comparison of findings in percutaneous transluminal angioplasty, thrombolysis, thrombus-extraction and stent-application.

Since the introduction of ultrathin angioendoscopes into clinical application, it has been possible to subject the findings of conventional or digital angiography to objective verification. In dogs and in patients, this new angioscopic method for visualization of arteries without surgical intervention has been carried out. The approach is transfemoral. Endoscopy is combined with angiography and, when indicated, percutaneous transluminal angioplasty (PTA), thrombolysis, thrombus extraction and insertion of a new type of stent. An ultrathin endoscope with an outer diameter of 1.6 mm and a working channel of 0.35 mm is used. Guidewires, contrast media and drugs for local thrombolysis can be employed through this channel. The endoscope is placed in the region of interest under fluoroscopy and direct visualization is obtained by using 0.9% NaCl for decreasing blood flow. Image recording is achieved by video or high-speed camera. With this method, the intraluminal events of dilatation, recanalization, local lysis, stent application and thrombus extraction can be visualized.

Angioplasty, Balloon↗

Visualization and recording of intravascular details by fiberoptic angioscopy: the Sumida cardioangioscope.

Direct selective observation of the intravascular lumen through a catheter cardioangioscope provides accurate diagnostic information that facilitates the detection and treatment of vascular diseases. The Sumida-cardioangioscope is approximately 0.75 to 2.4 mm in diameter and consists of at least 3,000-6,000 delicate glass fibers, each measuring 4.8-5.5 micron and fused into a long flexible 75 to 130 cm tube. The cardioangioscope has the following components: (1) a scope connected to a camera; (2) a lightguide, consisting of 80-500 fibers, measuring 30-50 micron in diameter, and a 75-watt xenon lamp; (3) a transport channel for saline or drug solution; (4) an inflatable cuff; and (5) a handle to manipulate the catheter tip. The abdominal aorta in living dogs and the coronary arteries, aortic valves, abdominal-iliac, femoral and popliteal arteries, abdomino-iliac bifurcation, and venous system were clearly observed and recorded on videotape, 16-mm movie film and 35-mm photographic film. Angioplasty by balloon and laser ablation are possible applications.

Adolescent↗

[Venous angioscopy].

Vascular endoscopy, especially of the venous system, allows a tri-dimensional evaluation and represents, to date, the best possible per-operative control of the diameter of the vessel. Under these conditions, venous thrombectomy may be performed more accurately; residual adherent parietal thrombi which may represent a possible source of emboli, may be eliminated. Venous endoscopy may be repeated several times; it does not result in any X-Rays exposure for the patient and enables to diagnose finer morphological details. Therapeutic measures under direct vision could even become possible in the future.

Endoscopy↗

Intraoperative angioscopy of saphenous vein and coronary arteries.

During coronary artery bypass graft operations, the saphenous vein graft and native coronary arteries in 17 patients were examined with a 1.7 mm fiberoptic catheter to determine the feasibility of the procedure and its potential for clinical application. Good to excellent visualization in 10 of 11 proximal and 10 of 10 distal coronary anastomoses was obtained promptly and consistently. Good visualization of native coronary arteries was obtained in only six of 11 vessels. Three of three coronary arteries were visualized through the completed distal anastomosis, whereas only three of eight vessels could be visualized directly through the arteriotomy site before completion of the distal anastomosis. The image quality improved with operator experience. Vessel distention by cold crystalloid solution during catheter visualization was also important for obtaining better images. Limitations of the current "state of the art" fiberoptic catheters include the large size relative to the usual dimensions of the native coronary vessels, a lack of perfusion channel, and the absence of an angulation or guiding system. Potentially, angioscopic catheters may be useful as an instructional aid during bypass operations or as a diagnostic tool in monitoring arterial status after thrombolytic intervention, balloon angioplasty, or laser therapy.

Cardiac Catheterization↗