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Results for “ANOSMIA”

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At least 325 records · Page 18Linked to original sources
PubMed1987

[Specific anosmia to isovaleric acid in the peripheral portion of the olfactory analyzer of the laboratory mouse].

The olfactory mucosa of laboratory male mice of lines C57BL/6 and AKR was stimulated by vapours of isovaleric acid and isoamylacetate of various concentrations. Study of electro-olfactography has demonstrated that mice of line C57BL/6 were insensitive to isovaleric acid of concentrations from 10(-5) to 10(-3) mol/l and remained normally sensitive to isoamylacetate. The mice of line AKR were sensitive to isovaleric acid of the same concentrations. The authors suggest using mice of these line as a model for investigations of the olfactory reception mechanisms.

Animals↗
PubMed1979

Evaluation of the hypothalamic-pituitary function in a female with hypogonadotropic hypogonadism and anosmia.

A case of Kallmann's syndrome in a woman is presented to evaluate the hypothalamic-pituitary function and status of the genital organs. The diagnosis of Kallmann's syndrome was performed under the determination of low circulating level of estradiol-17 beta and gonadotropins and low sensitivity to an olfactometer. Pituitary response to LRH was observed. Plasma LH response to LRH was observed in a lesser degree compared with the less impaired response of FSH. Daily injection of LRH for 13 days increased pituitary response of gonadotropin secretion. Diminished prolactin secretion and the dissociation of response to TRH and chlorpromazine were shown. Laparoscopic findings revealed a hypoplastic uterus and nearly normal sized ovaries. Ovarian response to exogenous gonadotropins was affirmed by increased estradiol-17 beta level. These results indicated disturbed hypothalamic control of gonadotropins and prolactin, and a reserved pituitary function in this case. Low circulating level of estradiol-17 beta might affect the heterogenous response of the hypothalamic-pituitary axis.

Adrenocorticotropic Hormone↗