SEARCH · Search PubMed

Results for “spatial localization”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

SourceResearch connectionFrom yearThrough year

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 307 records · Page 17Linked to original sources

PubMed1996

Frequency offset corrected inversion (FOCI) pulses for use in localized spectroscopy.

Gradient localized spectroscopy techniques suffer from a well documented spatial localization error caused by the difference in chemical shifts between resonances. This results in the acquisition of spectra from partially overlapping spatial regions of the sample, with each resonance representing a different region. The image-selected in vivo spectroscopy technique uses hyperbolic secant inversion pulses, where the main limitation in reducing this error is in the RF power available for application of the selective RF pulse. This spatial localization error may be dramatically reduced by increasing, and temporally shaping, the gradient pulse during slice-selective spin inversion. The performance of these RF pulses have been experimentally verified.

Magnetic Resonance Spectroscopy↗

PubMed1994

Role of multichannel magnetoencephalography in the evaluation of ablative seizure surgery candidates.

Magnetic source imaging (MSI) was performed on 30 ablative epilepsy surgery candidates. The technique involved high resolution multiplanar MRI images with lipid fiducials attached to the patient's head to define a head-based 3D coordinate space. Magnetoencephalography (MEG) was performed after digitizing the same fiducial points. A 37-channel magnetometer obtained data at two to five sites over each hemisphere. MEG epileptiform data were obtained with and without EEG triggering. A single equivalent current dipole model was used to determine orientation and location of a dipole generator whose surface isocontour map most closely fits the measured dipolar data for each event. The MEG data were then transformed to MRI images for source localization. In five of seven cases with ictal anterior temporal lobe foci, MSI data were localized to the same temporal lobe but did not provide additional spatial data. In 10 of 11 cases with convexity foci, MSI provided additional spatial localizing data. MSI did not verify depth electrode localization in one anterior temporal-orbital frontal and three orbitofrontal cases. In seven of eight cases in which depth EEG recordings were nonlocalizing, MSI provided insufficient localizing data. MSI appears to provide additional spatial localizing data in most cases with a convexity epileptic focus.

Analog-Digital Conversion↗

PubMed2026

A study on the differences in recovery effects of different types of nutritional supplements on competitive performance of esports athletes under mental fatigue.

BACKGROUND: To compare the effects of different nutritional supplements on the recovery of core competitive performance abilities in esports athletes following mental fatigue and to observe changes in the autonomic nervous system during recovery after nutritional supplementation by monitoring heart rate variability (HRV). METHODS: A randomized crossover within-subject controlled experimental design was adopted, including nutritional supplement type (caffeine, nitrate, Ginkgo biloba extract, catechins, placebo) × mental fatigue state (initial, fatigued, post-supplementation). Twenty high-level first-person shooter (FPS) esports athletes were recruited. Mental fatigue was induced using a Stroop task. After ingesting the different supplements and resting for 60 minutes, the participants completed assessments of shooting accuracy, shooting stability, spatial localization, and multitasking ability using the KovaaK's simulation trainer. HRV indices were also recorded to evaluate changes in autonomic regulation. RESULTS: For shooting accuracy, compared with the placebo condition, all four supplements significantly improved shooting accuracy scores following mental fatigue (all p < 0.05); however, no significant differences were observed among the effects of the different supplements. For shooting stability, caffeine, nitrate, and catechins produced significant recovery effects on shooting stability (all p  < 0.05); however, no significant differences were observed among the effects of these three supplements. For spatial localization and multitasking ability, the improvements in these two abilities in the post-supplementation state may have resulted from natural recovery, and none of the four nutritional supplements demonstrated a significant recovery effect. The HRV results showed that indices including RMSSD and SDNN changed under some supplement conditions. CONCLUSIONS: Mental fatigue significantly reduced the competitive performance of esports athletes. Four types of nutritional supplements all promoted the recovery of shooting accuracy, while caffeine, nitrate, and catechins promoted the recovery of shooting stability. However, no additional recovery advantages of the nutritional supplements over placebo were identified for spatial localization or multitasking ability. Changes in HRV may reflect changes in autonomic regulation during recovery, but further research is still warranted.

Humans↗

PubMed2000

Parametric localized modes in quadratic nonlinear photonic structures.

We analyze two-color spatially localized nonlinear modes formed by parametrically coupled fundamental and second-harmonic fields excited at quadratic (or chi(2)) nonlinear interfaces embedded in a linear layered structure--a quadratic nonlinear photonic crystal. For a periodic lattice of nonlinear interfaces, we derive an effective discrete model for the amplitudes of the fundamental and second-harmonic waves at the interfaces (the so-called discrete chi(2) equations) and find, numerically and analytically, the spatially localized solutions--discrete gap solitons. For a single nonlinear interface in a linear superlattice, we study the properties of two-color localized modes, and describe both similarities to and differences from quadratic solitons in homogeneous media.

Journal Article↗

PubMed2006

Nonparaxial fields with maximum joint spatial-directional localization. II. Vectorial case.

The monochromatic nonparaxial vector fields that achieve a minimum spatial spread for a given directional spread are found. The derivation of these fields is analogous to the one presented in part I of this series for the case of scalar fields. This derivation is based on a variational treatment and multipolar expansion. The resulting lower bounds for the spreads of vector fields turn out to be considerably more restrictive than for scalar fields.

Journal Article↗

PubMed1997

In vivo detection of GABA in human brain using a localized double-quantum filter technique.

A proton MR spectral editing technique employing a spatially localized, double-quantum filter (DQF) was used to measure gamma-aminobutyric acid (GABA) in the human brain at 1.5 T. The double-quantum method provided robust, single-shot suppression of uncoupled resonances from choline, creatine, and NAA and allowed detection of the gamma CH2 GABA (3.0 ppm) resonance with 30% efficiency. Spatial localization of the GABA measurement was achieved by incorporating PRESS localization within the double-quantum excitation and detection sequence. A calibration technique was developed to adjust the relative phases of the RF pulses to maximize the in vivo double-quantum detection efficiency for an arbitrary voxel location. The sequence efficiency, degree of suppression of uncoupled reasonances, and characterization of the in vivo DQF technique was examined in phantom experiments and in a study of the occipital lobe of 10 normal subjects. The ratio of the 3.0-ppm GABA resonance to the 3.0-ppm creatine resonance was found to be 0.20 +/- 0.05 (SD).

Brain Chemistry↗

PubMed2003

Threshold vision in amblyopia: orientation and phase.

PURPOSE: The visual deficit in amblyopia involves both elevated contrast thresholds and distorted suprathreshold percepts at high spatial frequencies. It is currently unclear whether these two anomalies are part of the same neural disturbance or whether they reflect different neural dysfunction. METHODS: The quality of the spatial percepts in amblyopia was assessed at detection threshold. The ability of amblyopes to discriminate the orientation and local spatial phase of well-localized spatial stimuli was measured at the detection threshold. Measurements were made as a function of spatial frequency. RESULTS: Performance seemed normal for orientation discrimination, even at high spatial frequencies, but, in some cases, it was disturbed in phase discrimination. CONCLUSIONS: A different explanation and neural basis is needed to encompass both threshold and suprathreshold spatial deficits in amblyopia.

Adult↗

PubMed1999

Spatial sensitization of increments and decrements: a border-contrast process and a net-excitation process.

We investigated the spatially local factors that adjust the sensitivity of the human visual system within a small patch of visual space. A very small adapting field was varied in diameter to map out the strength and extent of the spatially local processes that adjust sensitivity for both increments and decrements. The results demonstrated antagonistic center/surround adaptation regions with a decremental test probe comparable to those demonstrated previously for incremental probes (Westheimer, G., 1965. Spatial interaction in the human retina during scotopic vision, Journal of Physiology 81, 812-894; Westheimer, G., 1967. Spatial interaction in human cone vision, Journal of Physiology 190, 139-154) implying comparable antagonistic regions in the ON and OFF channels. In addition to spatial interactions based on light adaptation, we report a weaker effect that is based on the location of a border (luminance edge) and is governed by the contrast of this edge. Finally, we show that these effects are elicited by both highly localized edges (1' ring pairs) and radial lines (Ehrenstein figure) as well. We conclude that both a border-contrast mechanism and a net-excitation mechanism govern the spatially local adaptation of the visual system and that this view fits well with the behavior of single units reported previously.

Adaptation, Ocular↗

PubMed2003

Composite band-gap solitons in nonlinear optically induced lattices.

We introduce novel optical solitons that consist of a periodic and a spatially localized component coupled nonlinearly via cross-phase modulation. The spatially localized optical field can be treated as a gap soliton supported by the optically induced nonlinear grating. We find different types of these band-gap composite solitons and demonstrate their dynamical stability.

Journal Article↗

PubMed1993

Quantitative assessment of the microstructure of rat behavior: II. Distinctive effects of dopamine releasers and uptake inhibitors.

The effects of four indirect dopamine agonists, d-amphetamine (0.25-4.0 mg/kg), cocaine (2.5-40.0 mg/kg), GBR 12909 (10.0-30.0 mg/kg), and nomifensine (5.0-20.0 mg/kg), on the behavioral organization of movements in an unconditioned motor paradigm were investigated in rats. The extended scaling hypothesis using the fluctuation spectrum of local spatial scaling exponents was used to quantify the geometrical characteristics of movements. The results reveal a qualitatively similar disruption of behavioral organization by lower doses of these drugs. Specifically, rats treated with d-amphetamine (< 2.0 mg/kg), cocaine (< 20.0 mg/kg), GBR 12909 (< 20.0 mg/kg), or nomifensine (< 10.0 mg/kg) exhibited a reduced range in the fluctuation spectrum, reflecting a predominance of meandering movements with local spatial scaling exponents between 1.3 and 1.7. This reduction was accompanied dynamically by a reduced predictability of movement sequences as measured by the dynamical entropy, h. By contrast, higher doses of these drugs produced distinctly different changes in behavioral organization. In particular, 4.0 mg/kg d-amphetamine and 40.0 mg/kg cocaine increased the fluctuation range, reflecting relative increases in both straight and circumscribed movements that are interpreted as a combination of spatially extended and local perseveration. In contrast, high doses of 30.0 mg/kg GBR 12909 and 20.0 mg/kg nomifensine induced only local perseveration. High doses of d-amphetamine, cocaine, GBR 12909 and nomifensine reduced the dynamical entropy, h, indicating an increased predictability of the movement sequences. These results suggest that the generic behavioral change induced by low doses of dopamine agonists is characterized by a reduced variety of path patterns coupled with an increased variability in sequential movement sequences. The differential effects of higher doses of these drugs may be due to their influences on other neurotransmitter systems or differential affinities for different dopamine subsystems.

Animals↗

PubMed2006

Receptive field properties of neurons in the early visual cortex revealed by local spectral reverse correlation.

We introduce a novel class of white-noise analyses, named local spectral reverse correlation (LSRC), which is capable of revealing various aspects of visual receptive field profiles that were undetectable previously in a single simple measurement. The method is based on spectral analyses in a two-dimensional spatial frequency domain for spatially localized areas within and around their receptive fields. Extracellular single-unit recordings were performed for area 17 and 18 neurons in anesthetized cats. A dynamic dense noise pattern was presented in which the pattern covered an area two to three times larger than the classical receptive field. Spike trains were then cross-correlated with frequency spectra of localized noise pattern to obtain spatially localized selectivity maps in the two-dimensional frequency domain. Our findings are as follows. (1) The new LSRC method allows measurements of two-dimensional frequency tunings and their spatial extent even for cells with substantial nonlinearity. (2) A small subset of neurons shows spatial inhomogeneity in the two-dimensional frequency tunings. (3) In addition to facilitatory response profiles, we can also visualize suppressive profiles localized both in space and spatial frequency domains. Our results suggest that the new analysis technique can be a powerful tool for measuring visual response profiles that contain inhomogeneity in space, as well as for studying neurons with substantial nonlinearities. These features make the method particularly suitable for studying response profiles of neurons in early as well as intermediate extrastriate visual areas.

Action Potentials↗

PubMed1990

Proton spectral editing in the inhomogeneous radiofrequency field of a surface coil using modified stimulated echoes.

It is shown that the modified stimulated echo sequence, [theta](+/- x +/- y)-t1-[theta](+ x)-t2/2-[2 theta](+ x)-t2/2- [theta](+ x)-t1-Acq(+/- x +/- y), denoted as MSTE[2 theta]x according to the exciter phase of the 2 theta pulse, is able to perform proton spectral editing without difference spectra. On the other hand, this sequence appears to be suitable for spatial localization. Sensitivity and spatial selectivity of MSTE and conventional stimulated echo sequence (STE) are briefly compared. MSTE is applied to editing lactate in the rat brain using the locally restricted excitation of a surface coil.

Animals↗

PubMedDate not supplied

Conscious neurosensory mapping of the internal structures of the human knee without intraarticular anesthesia.

The conscious neurosensory characteristics of the internal components of the human knee were documented by instrumented arthroscopic palpation without intraarticular anesthesia. With only local anesthesia injected at the portal sites, the first author (SFD) had both knees inspected arthroscopically. Subjectively, he graded the sensation from no sensation (0) to severe pain (4), with a modifier of either accurate spatial localization (A) or poor spatial localization (B). The nature of the intraarticular sensation was variable, ranging from 0 on the patellar articular cartilage to 4A on the anterior synovium, fat pad, and joint capsule. The sensation arising from the cruciate ligaments ranged from 1 to 2B in the midportion, and from 3 to 4B at the insertion sites. The sensation from the meniscal cartilages ranged from 1B on the inner rim to 3B near the capsular margin. Innervation of most intraarticular components of the knee is probably crucial for tissue homeostasis. Failure of current intraarticular soft tissue reconstructions of the knee may be due, in part, to the lack of neurosensory restoration. Research studies of the knee designed to delineate factors that restore neurosensory characteristics of the musculoskeletal system may lead to techniques that result in true restoration of joint homeostasis and function.

Anesthesia, Local↗

PubMed1998

[Temperature stress for patients in routine magnetic resonance examinations].

PURPOSE: To determine energy exposure and temperature changes in routine magnetic resonance imaging practice. MATERIALS AND METHODS: Body core and skin temperatures were compared in 155 persons (143 patients, 12 volunteers) undergoing routine magnetic resonance examinations with a 1.5 T field-strength magnetic resonance tomography unit using a fluoroptic temperature measurement system. RESULTS: Average applied energy was 0.3 W/kg for whole body and 1.92 W/kg for spatially localized SAR. The maximum whole-body SAR was 1.43 W/kg spatially localized. Body core temperatures differed from those of the control group by a median 0.1 degree C and only a few patients (16.8%) exceeded the limit (+/- 0.5%) at which regulatory mechanisms set in. All patients remained within the normal physiological circadian temperature range (+/- 1 degree C). Skin temperature rose a median 0.49 degree C, with a maximal increase of 5.31 degrees C, which may be considered to be within the limits of physiological temperature change. CONCLUSIONS: Clinically relevant warming of the body is unlikely in routine magnetic resonance imaging practice.

Adolescent↗

PubMed1996

The role of inferior parietal cortex and fornix in route following and topographic orientation in cynomolgus monkeys.

The effects of inferior parietal cortex lesions (Area 7a/PG) and bilateral transection of the fornix were compared within a single species (cynomolgus monkeys) and using a single paradigm of route running in a traditional (fixed entry and exit) whole-body maze. Experiment 1 showed that Area 7a/PG but not fornix lesions impaired post-operative retention of route running. Experiment 2 assessed the contribution of visual cues and proprioceptive/kinaesthetic guidance to route running and showed that in non-lesioned monkeys route running was influenced to varying degrees by proprioceptive guidance, visual extra-maze room cues and visual maze stimuli. Post-operative assessment of maze performance, including error patterns, retraining and misreaching (Experiment 1), suggested that monkeys in the Parietal Group were not topographically disoriented and did not have a spatial long-term memory deficit, but it was their difficulty responding to local spatial cues which initially impaired route running. Investigation of cue use (Experiment 2) also showed the sensitivity of the Parietal Group to local spatial cues; they were significantly impaired on entry through a new start position when the relationship between maze stimuli and extra-maze cues was changed. The Fornix Group showed no retrograde long-term memory deficit for route-running (Experiment 1). However, in Experiment 2, where a new goal position was learnt, the Fornix Group did show an anterograde memory deficit.

Animals↗

PubMed1998

Constructive incremental learning from only local information

We introduce a constructive, incremental learning system for regression problems that models data by means of spatially localized linear models. In contrast to other approaches, the size and shape of the receptive field of each locally linear model, as well as the parameters of the locally linear model itself, are learned independently, that is, without the need for competition or any other kind of communication. Independent learning is accomplished by incrementally minimizing a weighted local cross-validation error. As a result, we obtain a learning system that can allocate resources as needed while dealing with the bias-variance dilemma in a principled way. The spatial localization of the linear models increases robustness toward negative interference. Our learning system can be interpreted as a nonparametric adaptive bandwidth smoother, as a mixture of experts where the experts are trained in isolation, and as a learning system that profits from combining independent expert knowledge on the same problem. This article illustrates the potential learning capabilities of purely local learning and offers an interesting and powerful approach to learning with receptive fields.

Journal Article↗

PubMed1989

Double dissociation of egocentric and allocentric space following medial prefrontal and parietal cortex lesions in the rat.

Animals with medial prefrontal cortex or parietal cortex lesions and sham-operated and non-operated controls were tested for the acquisition of an adjacent arm task that accentuated the importance of egocentric spatial localization and a cheese board task that accentuated the importance of allocentric spatial localization. Results indicated that relative to controls, animals with medial-prefrontal cortex lesions are impaired on the adjacent arm task but displayed facilitation on the cheese board task. In contrast, relative to controls, rats with parietal cortex lesions are impaired on the cheese board task but show no impairment on the adjacent arm task. The data suggest a double dissociation of function between medial prefrontal cortex and parietal cortex in terms of coding of egocentric versus allocentric spatial information.

Animals↗

PubMed1993

Contrast sensitivity and vernier acuity in amblyopic monkeys.

Human psychophysical studies suggest that strabismic and anisometropic amblyopes may have characteristically different patterns of visual loss. In particular, anisometropic amblyopes often show deficits on spatial localization tasks that scale with their spatial resolution losses, whereas strabismic amblyopes can show localization deficits that are large relative to their losses in spatial resolution. We have compared the performance of non-human primates with experimentally-induced anisometropic and strabismic amblyopia on contrast detection and vernier acuity tasks. The performance of both groups of animals was fundamentally similar: both strabismic and anisometropic monkeys showed deficits in spatial localization that were large relative to their resolution losses, although the animals with the most disproportionate losses were strabismic. We investigated the extent to which contrast sensitivity losses accounted for the vernier acuity deficits. The results showed that, in most cases of either strabismic or anisometropic amblyopia, when the vernier stimuli for each eye were equated in terms of effective contrast, the extent of the vernier acuity deficit was reduced to approximately the extent of the spatial resolution deficit. In two cases, both of strabismic amblyopia, we found that equating the stimuli in this way was not sufficient to make the deficits equal, a pattern that has been described for human strabismic amblyopes.

Amblyopia↗