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Results for “Yin Deficiency”

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At least 307 records · Page 17Linked to original sources
PubMed2004

[Clinical observation on effect of Yiqi Yangyin Huoxue Tongfu principle in treating diabetes mellitus type 2 of secondary failure to sulfonylurea agents].

OBJECTIVE: To observe the effect of Yiqi Yangyin Huoxue Tongfu (YYHT) principle in treating diabetes mellitus type 2 of secondary failure to sulfonylurea agents. METHODS: Forty patients were randomly divided into two groups, based on the unchanged previous treatment of sulfonylurea agents, Chinese decoction prescribed according to YYHT principle was given to the treated group and rosiglitazone was given to the control group. Changes of insulin sensitivity (SI), insulin response to glucose (IRG), insulin sensitive index (ISI), tumor necrosis factor-alpha (TNF-alpha), endothelin-1 (ET-1), 6-keto-prostaglandin F1alpha(6-keto-PGF1alpha) and thromboxane B2 (TXB2) were observed. RESULTS: The total effective rate in the treated group was 71.4%, that on improving peripheral insulin resistance was 76.2%, the two parameters were similar to those in the control group. In the treated group, SI, ISI were significantly improved, and TNF-alpha, ET-1 and TXB2 significantly lowered, but no change of IRR was found. CONCLUSION: Application of YYHT principle in treating patients with diabetes mellitus type 2 of secondary failure to sulfonylurea agents could alleviate the peripheral resistance to insulin, inhibit TNF-alpha, and protect the vascular endothelial cells.

Adult↗
PubMed2004

[Effect of radix Rehmanniae preparata on the expression of c-fos and NGF in hippocampi and learning and memory in rats with damaged thalamic arcuate nucleus].

OBJECTIVE: To study the effect of Radix Rehmanniae Preparata (RRP) on improving the function of learning and memory. METHOD: With injured thalamic arcuate nucleus rats induced by MSG, the improving function of RRP on learning and memory was observed by step down task and Morris water maze task, and the expression of c-fos and NGF in hippocampi was observed by immunohistochemical means. RESULT: RRP could decrease the times of mistakes and prolong the incubation period in step down task, shorten the incubation period of seeking the platform, and improve the rate through the platform position in Morris water maze task. RRP could also increase the expression of hippocampal NGF, c-fos. CONCLUSION: RRP could improve the function of learning and memory of MSG rats, and its mechanism may by related with the increase of the expression of hippocampal c-fos and NGF.

Animals↗
PubMed2005

Regulative actions of the Chinese drugs for tonifying the kidney on gene expression of the hypothalamic GnRH, pituitary FSH, LH and osteoblastic BGP.

It is found that the drugs for nourishing yin to reduce pathogenic fire can significantly down-regulate, and the drugs for tonifying the kidney to replenish essence can up-regulate mRNA expression of the hypothalamic GnRH, pituitary FSH, LH and osteoblastic BGP, indicating that the Chinese drugs for tonifying the kidney can regulate gene expression of the hypothalamic GnRH, pituitary FSH, LH, and osteoblastic BGP, which is possibly one of the main mechanisms of the Chinese drug for tonifying the kidney, regulating ephebic development process andimproving skeletal development in sexual precocity children.

Animals↗
PubMed1992

[Treatment of IgA nephropathy by integrated traditional and Western medicine].

45 cases of IgA nephropathy were confirmed by renal biopsy and were divided into 2 groups, the integrated traditional and western medicine (TCM-WM) therapeutic group and the western medicine (WM) therapeutic group. The WM group was treated by conventional western medicine (persantin, vitamin B co.), and the TCM-WM group was treated by the same western medicine plus differential symptomatic treatment with decoction of Chinese crude herbs. In this paper, most patients (30 cases) were present as deficiency of Yin of the Liver and Kidney type, and were treated by Qiju Dihuang pill plus Erzhi pill. All types in TCM-WM group were also used herbs of promoting blood circulation and remove blood stasis in almost every case. After 6 months of such treatment, the total effective rate of TCM-WM group and the WM group were 86.4% and 13.0% respectively. There was very significant difference (P less than 0.01) between them. The results showed that the curative effect of the TCM-WM group was much superior than WM alone for the treatment of IgA nephropathy.

Adolescent↗
PubMed2005

[Protective effect of zuogui pill on ovarian autoimmune injury].

OBJECTIVE: To probe the effect of Zuogui pill (ZGP), a Chinese compound recipe for tonifying Shen, on ovarian function in mice with premature ovarian failure (POF). METHODS: BALB/C female mice model of POF was established by multiple sites subcutaneous injection of ovarian antigen elicited with ovarian tissue of SD female rats, and treated with ZGP at different time points in the modeling, with prednisone as positive control. The levels of follicle-stimulating hormone (FSH) and estradiol (E2) in peripheral blood were measured with radioimmunoassay, and ovarian antibody (AoAb) was determined by enzyme linked immunosorbent assay. The mRNA expression of ovarian growth and differentiation factor-9 was detected with in situ hybridization. RESULTS: POF model mice manifested such abnormalities as increased FSH, decreased E2, and positive AoAb in peripheral blood, with lymphocytes infiltration in ovarian mesanchyma, reduction of GDF-9 mRNA positive oocytes, and decrease of growing and mature follicles. ZGP could reduce the increase of FSH, increase the level of E2, inhibit the production of AoAb, raise the GDF-9 mRNA positive cells of oocytes, increase the number of growing and mature follicles. The clinical efficacy was more significant in early stage than in advanced stage. CONCLUSION: ZGP can improve immune inflammatory injury of ovary, and shows therapeutic effect on POF.

Animals↗
PubMed2006

[Clinical effect of treatment for clearing heat, detoxicating and nourishing Yin on patients with glucocorticosteroid induced facial dermatitis and its effect on skin barrier function].

OBJECTIVE: To observe the clinical efficacy of treatment for clearing heat, detoxicating and nourishing Yin (abbr. as CHM) on glucocorticosteroid (GCS) induced facial dermatitis, and its effect in repairing skin barrier function. METHODS: One hundred and fifteen patients were randomly assigned into two groups, 68 in the treated group treated with CHM and 47 in the control group treated by oral administration of loratadine 10 mg once a day and ketotifen 1 mg once every night. The volume of transepidermal water loss (TEWL) of patients was measured before and after treatment. RESULTS: The effective rate was 77.9% (53/68) and 14.9% (7/47) in the treated group and the control group respectively, showing significant difference between the two groups, and it was better in the treated group than that in the control group (P < 0.01). The decrease of TEWL in the treated group was also superior to that in the control group (P < 0.01). CONCLUSION: Chinese herbal treatment for clearing heat, detoxicating and nourishing Yin has significant clinical efficiency on GCS induced facial dermatitis and in repairing the skin barrier function.

Adolescent↗
PubMed2006

[Effects of Chinese herbal medicine for Yiqi Yangyin Quyu in treating Sjögren's syndrome and on patients' immunologic function].

OBJECTIVE: To investigate the immuno-regulatory and therapeutic effects of Chinese herbal medicine for Yiqi Yangyin Quyu (YYQ, supplementing qi, nourishing yin, removing blood stasis) on Sjögren's syndrome (SS). METHODS: Sixty-two patients were randomly divided into the treated group (37 cases) treated with Chinese medicine and prednisone, and the control group (25 cases) treated with prednisone alone, and another 20 healthy persons were taken as the normal control group. Curative effects was observed, and immunoglobulin (Ig) and T lymphocyte subsets were detected before and after 3 months' treatment. RESULTS: Immunoglobulin (IgG, IgM and IgA) before treatment in SS patients were higher, while the proportion of natural killer (NK) cell and CD4 were lower as compared with those in the normal control group. After treatment, IgG, IgM and IgA lowered to normal levels (P < 0.05), the proportion of NK cell and CD4 rose in both groups (P < 0.05), but CD3 in the control group was still lower than that in the treated group (P < 0.05). The total curative effective rate in the treated group was 91.9%, better than that in the control group (76.0%, chi-squared = 3.92, P < 0.05). CONCLUSION: Chinese herbal medicine for YYQ could improve clinical curative effective rate and regulate immune function in SS patients.

Adult↗
PubMed2006

[Clinical study on effects of tiepi fengdou granule/capsule combined with chemotherapy and/or radiotherapy in treating lung cancer with Qi-Yin asthenia syndrome].

OBJECTIVE: To study the clinical efficaly and safety of Tiepi Fengdou Granule (TFG) and Capsule (TFC) combined with chemotherapy and/or radiotherapy in treating lung cancer patients with Qi-Yin asthenia syndrome (QYAS). METHODS: Eighty patients were randomly assigned into 3 groups: the TFG group (32 cases), the TFC group (32 cases) and the Shengmai Capsule control group (16 cases). Changes of symptoms of QYAS, main symptoms of lung cancer, Karnofsky scoring as well as the blood routine test were observed. RESULTS: The total effective rate of symptom improving in the TFG group and the TFC group was 81.2% and 93.3% respectively, showing insignificant difference between the 2 groups (P > 0.05), but both were higher than that in the Shengmai Capsule control group (50.0%, P < 0.05 and P < 0.01). Additionally, as compared with those before treatment, the neutrophil count increased and the lymphocytes count obviously decreased in the TFC group after treatment (all P < 0.05). CONCLUSION: Both dose-forms of the remedies, TFC and TFG, have significant effects in treating lung cancer with QYAS, but with insignificant difference between them.

Adult↗
PubMed1990

[Clinical study on xintongkang capsule in treating angina pectoris of coronary heart disease].

Two hundred and sixty seven cases of angina pectoris of coronary heart disease (male 152, female 115, age 41--79) were studied. Among these, 195 cases were patients with effort angina, 72 cases with non-effort angina. Double blind stratified randomized grouping, differentiation- syndromes treatment of TCM and self-control observation methods were applied. The results showed that total effective rate was 93.3% for angina pectoris in the treatment group. While control group which were treated by persantin and aspirin was 54.7% (P less than 0.001). For resting ECG evaluation total effective rates were 52.78% and 13.51% respectively. The ECG exercise testing (protocol Bruce) and dynamic ECG also showed the results similar to that of resting ECG. According to differentiation-syndromes treatment of TCM. The effect of Xintongkang capsule on simple stagnation of Qi and stasis of blood, or combined with deficiency of Qi, or combined with deficiency of Yin was better than other symptoms. The effect of Xintongkang capsule initiated in the second week after oral medicine, peak response occurring in the fourth week, and it trend to the stability in the eighth week. There was no harmful effect to heart, liver, kidney and blood. No allergic reactions were found in this observation.

Adult↗
PubMed1995

[Clinical and experimental study on codonopsis pilosula oral liquor in treating coronary heart disease with blood stasis].

The effects of Codonopsis pilosula oral liquor (CPOL) on tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor (PAI) in the plasma of 25 patients of coronary heart disease with blood stasis were studied. It has been shown that those patients had a significant decrease in t-PA activity (P < 0.01) compared to healthy subjects. After 4 weeks of CPOL therapy, platelet aggregation significantly decreased (P < 0.05), there was no significant difference in t-PA and PAI. From the results shown above, it suggested that one of the effects of CPOL in influencing blood coagulation was its inhibition on platelet aggregation, but not through the elevating of fibrinolytic activity.

Adult↗
PubMed1994

[Immunological observation on chyluric patients with heat-clearing and hemostatic drugs].

In order to investigate the pathogenesis and therapeutic mechanism of chyluria, an experiment with a basic Heat-clearing and hemostatic prescription was conducted in treating 30 patients of chyluria. The result, 26 cases were cured completely. The cell-mediated and humoral immunity observation showed that OKT3 and OKT4 levels were commonly low in chyluric cases, and OKT8 as higher than normal value, the OKT4/OKT8 ratio was inverted before treatment. While OKT3 and OKT4 increased commonly, and OKT8 decreased with the OKT4/OKT8 ratio adjusted after treatment. Meanwhile, humoral immunity level was also commonly low before treatment, it increased after treatment.

Adult↗
PubMed1993

[Herbal decoction of qingwen baidu yin in treating endotoxic fever in rabbits].

Qingwen Baidu Yin (QBY) has good curative effects on the endotoxic fever of rabbits induced by injecting endotoxin of E. Coli. The test group was given QBY orally, while the control group was given NS orally instead. Result showed QBY could: (1) Markedly inhibit the fever, it was effective in reducing febrile curve. delta T and TRI5 of the test group were smaller (P < 0.001). (2) Ameliorate the leukocytopenia and leukocytosis, and improve thrombocytopenia. (3) Antagonize hyperviscosity syndrome and had the actions of depolymerization and dilution. (4) In test group, the increased cAMP content in plasma was reduced, and the decreased cGMP content raised, the ratio of cAMP and cGMP was nearly normal. All these provided the clue in elucidating the essence of "Excessive Yang causes Heat" and "Predominance of Yang leads to disorder of Yin". (5) Pathomorphological examination showed that QBY had the functions of protecting the internal organs and reducing the organic damage induced by endotoxing in rabbits.

Animals↗
PubMed1993

Treatment of diabetes in the elderly--an analysis of 885 cases.

Besides treating elderly diabetics basically for the disease, the author treated the patients by traditional Chinese medicine based on an overall analysis of their symptoms and signs, dividing the course of the disease into 5 stages comprising 16 syndromes types. He evaluated the quality of their survival according to an the health rating of Karnofsky, and advised them on the amount of work or other activity appropriate in each case in order to relieve the symptoms, retard the disease process, and improve the quality of survival.

Aged↗