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At least 307 records · Page 17Linked to original sources
PubMed1991

Plague and tularemia.

Human plague is a local or systemic flea-transmitted infection caused by Yersinia pestis. It is maintained in well established enzootic foci among wild rodents. This article discusses the clinical findings in plague, diagnosis, treatment, and prevention of plague, and management of contacts of human plague cases and of exposures to epizootic plague. Tularemia shares many features with plague but is widespread in animal and arthropod vector populations and essentially throughout the United States.

Animals↗
PubMed1990

[The meadow-field type of tularemia foci in eastern Siberia].

The article characterizes a meadow-type focus tularemia, discovered in Zalarinski'i District of Irkutsk Province in 1988. This focus and another similar focus discovered in 1985 at the Krasnoyarsk Territory belong to the meadow type, which makes it possible to regard their presence in Eastern Siberia as an established fact. The main reservoirs and sources of infection in these foci are two species of voles (Microtus gregalis and M. subarvalis).

Animals↗
PubMed1989

[Delayed type hypersensitivity reaction in the pathogenesis and formation of immunity in tularemia infections in mice].

As a result of our studies, strain differences in the sensitivity of CBA and BALB/c mice to partially attenuated Francisella tularensis strain have been revealed. Relationship between the increased migration of lymphocytes to the liver and lymphoid organs and the intensive development of cell-mediated immunity reactions has been shown. An important role of local reactions (the skin at the site of the inoculation of F. tularessis + a regional lymph node) in the development of the pathological process and the formation of immunity to tularemia infection has been noted. A high level of resistance to F. tularensis strain used for inoculation in BALB/c mice seems to be greatly due to the fact that in these mice more intensive cell-mediated immunity reactions develop at the early stages of infection, than in CBA mice.

Animals↗
PubMed1985

Adult respiratory distress syndrome secondary to tularemia pneumonia.

Three patients with tularemia pneumonia developed adult respiratory distress syndrome and required positive end-expiratory pressure for adequate oxygenation. Rapid improvement was noted following appropriate antibiotic therapy, and mechanical ventilation was successfully discontinued after six to eight days.

Adult↗
PubMed1980

Fatal-cat trasmitted tularemia: demonstration of the organism in tissue.

The case reported represents an unusual mode of transmission of tularemia from cat to man, with fatal outcome. The use of the modified Dieterle spirochete stain demonstrated F tularensis in tissue when all other routine stains failed. Direct immunofluorescent staining confirmed the presence of the organism in tissue sections. F tularensis and the etiologic agent of Legionnaires' disease are similar only in their ability to stain with the modified Dieterle stain and their inability to stain with conventional histochemical technics.

Aged↗
PubMed1978

An outbreak of tularemia in mink.

An outbreak of tularemia in farm raised mink is reported. Twenty-six of approximately 5000 mink succumbed within a 10 day period. Prodromal signs were minimal. Necropsy revealed necrotic nodules scattered in the parenchyma of the lungs, liver, spleen, and mesenteric lymph nodes. Francisella tularensis was isolated from spleens, livers and lungs.

Animals↗
PubMed1982

[Results of prolonged study of flood plain-swamp endemic foci of tularemia, and its prophylaxis in the Leningrad Region].

The results of a prolonged (more than 18 years), comprehensive study have revealed that stable natural foci of tularemia in backwater swamps are widely spread in the Leningrad region. These foci are located in the narrow swampy flood-plains of small watercourses with adjacent meadow areas among forests. Water from such small watercourses can often serve as the indicator of the epizootic process: during the above-mentioned period 346 Francicella tularensis strain have been isolated from water and 86 strains from small mammals. The water factor plays an important role in the circulation of the infective agent in natural foci.

Animals↗
PubMed1984

[Focal nature of tularemia along the course of the Irtysh-Karaganda Canal].

The results of the epizootological survey of the track of the Irtysh-Karaganda canal for tularemia for the period of 1971-1982 are presented. Out of 928 fecal samples from mouse-hunting birds, 16 contained the specific antigen. From Arctic shrews a strain of Francisella tularensis was isolated.

Animals↗
PubMed1984

[Tularemia on the Kola Peninsula].

In 1982 Francisella tularensis was isolated for the first time on the Kola Peninsula from rodents caught in the environs of Kirovsk and Nickel. This fact confirmed the suggestion concerning the existence of the natural foci of tularemia on the Kola Peninsula.

Animals↗
PubMed1980

[Isolation of the causative agent of tularemia from an inoculum from skin lesions in the ulcerobubonic form of the disease].

A case of tularemia in a human patient infected through the sting of a gadfly (Tabanus) is described. The causative agent of the disease was isolated from the patient with the ulcerobubonic form of the disease by the method of the direct inoculation of the contents of the patient's cutaneous effect. The properties of the isolated culture were established; the strain thus obtained was classified as a representative of the geographical race Francisella tularensis holarctica 01s. The causative agent circulating in the human patients was found to be fully virulent.

Agglutination Tests↗
PubMed1984

[2 cases of tularemia observed at Monte Amiata].

Two cases of tularemia caused by direct contact with an infected hare are described. Recent epidemiological discoveries about the disease are reported with reference to other known foci in Tuscany and the measures taken to control and isolate the infected areas.

Adult↗
PubMed1983

Tularemia pneumonia mimicking legionnaires' disease: isolation of organism on CYE agar and successful treatment with erythromycin.

A 46-year-old man showed a clinical response when treated with parenteral erythromycin for what was initially thought to be legionnaires' disease, but an organism isolated from his pleural fluid on CYE agar was subsequently identified as Francisella tularensis. Tularemia should be suspected in all cases of atypical pneumonia in the appropriate setting. Erythromycin may be effective empiric therapy in such cases. Because of the possibility of inadvertent isolation of Francisella tularensis on CYE agar, all cultures for suspected Legionella should be handled with extreme caution, preferably in a biological hood.

Charcoal↗
PubMed1982

[Cytochemical changes in the peripheral blood leukocytes of guinea pigs inoculated against plague, tularemia and anthrax].

The immunization of guinea pigs with trivaccine and monovaccines against plaque, tularemia and anthrax induces a decrease in the activity of acidic phosphatase in lymphocytes, as well as a decrease in the number of lymphocytes containing this enzyme. A decrease in the activity of alkaline phosphatase and peroxidase had been found to occur in neutrophil leukocytes. Besides, neutrophil leukocytes have shown an increase in the activity of acidic phosphatase and nonspecific esterases. The study based on the evaluation of the activity of the above-mentioned enzymes in lymphocytes and neutrophils has not revealed the predominant influence exercised by any of the antigens, different in their nature and used separately or in the form of a combined preparation, on immunogenesis.

Animals↗
PubMed1978

[Present-day status of tularemia prevention in the USSR and further tasks].

Despite the presence of natural foci of infection at the territory of all the Union republics (excluding the Kirghiz SSR) and intensive epizootics among rodents, tularemia in the USSR is under full control from 1965. Further differentiation of antitularemia measures, depending on local conditions of economy management and the presence of natural foci of infection is necessary.

Animals↗
PubMed1995

[The effect of tularemia vaccine on some parameters of immune and non-specific anti-tumor resistance in patients with endometrial tumors].

On days 15-20 after immunization of patients suffering from endometrial tumors with tularemia live vaccine, a significant increase was registered in T-cell population of the immune system, macrophagal transformation of mononuclears and phagocyticity of blood neutrophiles which are generally reduced in stages III-IV. The study group included cases of all tumor stages. Said indices reached normal levels in stage I-II only.

Bacterial Vaccines↗
PubMed1994

Tularemia.

Clinical and histologic characteristics of tularemia are reviewed in this report of a 65-year-old man who presented with fever, cutaneous ulceration, and regional lymphadenopathy. Examination of a biopsy specimen failed to demonstrate the granulomatous inflammation one would expect according to the current dermatologic literature. We review the diagnostic implications of this finding.

Aged↗
PubMed1977

[Dynamics of immunoglobulins M and G formation in experimental tularemia].

There were revealed certain differences in the structure and the level of immunoglobulins, the time of their persistence in the blood of the infected and vaccinated experimental animals in tularemia. IgG were characteristic chiefly of the infectious process and served as an index of the immunological response intensity. Vaccination conditioned the production of IgM. IgG were revealed in low titres and at earlier periods of study. The results coincided in using cystein hidrochloride and 2-mercaptoethanol (reducing agents).

Agglutination Tests↗
PubMed1997

[Cervicofacial manifestations of tularemia. Apropos of a familial case].

Tularemia is a rare infectious disease, due to Francisella tularensis, a virulent bacterium transmitted by a carrier insect (essentially ticks) or by the meat of an infected animal (generally hares). We report 3 cases that occurred in the same family, showing the various symptoms of this disease. Revealing head and neck manifestations may mislead diagnosis.

Adolescent↗