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At least 307 records · Page 17Linked to original sources

Comparison of keratometric readings as obtained by Javal Ophthalmometer and Corneal Analysis System (EyeSys).

We examined 92 normal eyes using Javal Ophthalmometer and Corneal Analysis System (EyeSys) intending to compare the keratometric readings obtained by these two instruments. Dioptric power and location at flatter and steeper meridians, keratometric astigmatism values, and average central keratometric power were measured in the central cornea of all eyes. Statistical analysis showed significant differences in flatter meridians' mean power values (mean difference = 0.13 D, P = .008), mean keratometric astigmatism values (mean difference = -0.20 D, P = .001) and steeper meridians' location (mean difference = 7 degrees, P = .0001). There was no significant difference in steeper meridians' mean power values (mean difference = -0.06 D, P = .38), flatter meridian location (mean difference = 5.9 degrees, P = .07), and mean average central keratometric power (mean difference = 0.03 D, P = .471). Clinically meaningful difference was observed only in keratometric astigmatism readings of eyes with keratometric astigmatism higher than 1.50 D (mean difference = -0.84 D). For all the other parameters measured, the differences between the two instruments readings were clinically acceptable.

Adolescent↗

A longitudinal study of intralimb coordination in the first year of independent walking: a dynamical systems analysis.

Using a dynamical systems approach, we examined the development of intralimb coordination over the first year of independent walking. The segmental motion of the thigh and shank and their intralimb coordinative relationship were modeled dynamically as a system of coupled limit cycles. To test the predictions of such a dynamic model in the development of intralimb coordination, 3 infants were filmed from the onset of their first upright independent walking steps, and weekly for the next month and then every month thereafter until they had been walking for 1 year. 3 adults also were included for comparison. Analysis of the kinematic data derived from the film revealed that at the emergence of walking, the limit cycle system displayed instability in several aspects. With walking experience, however, the limit cycle regime became more attractive, such that by 3 months of walking the infants appeared to have found an adult-like stable coordinative relationship between the 2 segments. This pattern of instability followed by stability is consistent with the transitional behaviors of dynamical systems. Several potential control parameters are discussed that might contribute to the stabilization of the walking behavior. The utility of employing a dynamical systems approach for understanding developing behavioral systems is discussed.

Female↗

[A systems analysis of the value of the psychophysiological characteristics obtained by using the family of Rhythmo-, Mnemo- and Binatest microprocessor apparatus].

The application of methodology of applied systems analysis of the extensive continuum of means and methods for assessing the human nervous and mental sphere may reveal high systems forming properties of psycho-physiological characteristics determined by a family of Rhythmo-, Mnemo-, Binatest microprocessor equipment. There is evidence for high feasibility and efficiency of multiparametric and polymethodological principles laid in the design of microprocessor equipment.

Adult↗

Systems analysis of cerebrovascular pressure transmission: an observational study in head-injured patients.

In an observational study in head-injured patients, cerebrovascular pressure transmission was investigated using a systems analysis approach whereby the blood pressure (BP) waveform was used as a measure of an input stimulus to the cerebrovascular bed (CVB) and the intracranial pressure (ICP) waveform as the response to that stimulus. The transfer function is a measure of how much pressure is transmitted through the CVB at a given frequency and is calculated using Fourier analysis of the pressure waveforms. The transfer function allows quantification of the pressure transmission performance of the CVB, thus providing a basis for comparison between normal and abnormal function. Fifteen hundred samples of ICP and BP waveforms were collected from 30 head-injured patients via microcomputer. Off-line spectral analysis of the waveform database revealed four main classes of transfer function: those with an overall flat transfer function (curve type 1); those with an elevated low-frequency response (curve type 2); those with an elevated high-frequency response (curve type 3); and those exhibiting both an elevated low- and high-frequency response (curve type 4). Curve types 2 and 4 were most often associated with raised ICP (greater than 20 mm Hg), whereas curve types 1 and 3 were most often affiliated with ICP less than 15 mm Hg. Studies of this type may provide insight into the pathophysiology of the CVB and ultimately aid in the prediction and treatment of raised ICP.

Adolescent↗

Computational Proteomics Analysis System (CPAS): an extensible, open-source analytic system for evaluating and publishing proteomic data and high throughput biological experiments.

The open-source Computational Proteomics Analysis System (CPAS) contains an entire data analysis and management pipeline for Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) proteomics, including experiment annotation, protein database searching and sequence management, and mining LC-MS/MS peptide and protein identifications. CPAS architecture and features, such as a general experiment annotation component, installation software, and data security management, make it useful for collaborative projects across geographical locations and for proteomics laboratories without substantial computational support.

Computational Biology↗

Computer modeling for advanced life support system analysis.

This article discusses the equivalent mass approach to advanced life support system analysis, describes a computer model developed to use this approach, and presents early results from modeling the NASA JSC BioPlex. The model is built using an object oriented approach and G2, a commercially available modeling package Cost factor equivalencies are given for the Volosin scenarios. Plant data from NASA KSC and Utah State University (USU) are used, together with configuration data from the BioPlex design effort. Initial results focus on the importance of obtaining high plant productivity with a flight-like configuration.

Atmosphere↗

New bioimpedance analysis system: improved phenotyping with whole-body analysis.

OBJECTIVE: Bioimpedance analysis (BIA) is a potential field and clinical method for evaluating skeletal muscle mass (SM) and %fat. A new BIA system has 8-(two on each hand and foot) rather than 4-contact electrodes allowing for rapid 'whole-body' and regional body composition evaluation. DESIGN: This study evaluated the 50 kHz BC-418 8-contact electrode and TBF-310 4-contact electrode foot-foot BIA systems (Tanita Corp., Tokyo, Japan). SUBJECTS: There were 40 subject evaluations in males (n=20) and females (n=20) ranging in age from 6 to 64 y. BIA was evaluated in each subject and compared to reference lean soft-tissue (LST) and %fat estimates in the appendages and remainder (trunk+head) provided by dual-energy X-ray absorptiometry (DXA). Appendicular LST (ALST) estimates from both BIA and DXA were used to derive total body SM mass. RESULTS: The highest correlation between total body LST by DXA and impedance index (Ht(2)/Z) by BC-418 was for the foot-hand segments (r=0.986; left side only) compared to the arm (r=0.970-0.979) and leg segments (r=0.942-0.957)(all P<0.001). The within- and between-day coefficient of variation for %fat and ALST evaluated in five subjects was <1% and approximately 1-3.7%, respectively. The correlations between 8-electrode predicted and DXA appendicular (arms, legs, total) and trunk+head LST were strong and highly significant (all r> or =0.95, P<0.001) and group means did not differ across methods. Skeletal muscle mass calculated (Kim equation) from total ALST by DXA (X+/-s.d.)(23.7+/-9.7 kg) was not significantly different and highly correlated with BC-418 estimates (25.2+/-9.6 kg; r=0.96, P<0.001). There was a good correlation between total body %fat by 8-electrode BIA vs DXA (r=0.87, P<0.001) that exceeded the corresponding association with 4-electrode BIA (r=0.82, P<0.001). Group mean segmental %fat estimates from BC-418 did not differ significantly from corresponding DXA estimates. No between-method bias was detected in the whole body, ALST, and skeletal muscle analyses. CONCLUSIONS: The new 8-electrode BIA system offers an important new opportunity of evaluating SM in research and clinical settings. The additional electrodes of the new BIA system also improve the association with DXA %fat estimates over those provided by the conventional foot-foot BIA.

Absorptiometry, Photon↗

Eye movement analysis system using computerized image recognition.

A new technique for an eye movement analysis system utilizing infrared video recording and a computerized image recognition method is presented. The system consists of an infrared lighting apparatus, a very small infrared video charge-coupled device camera, a video tape recorder, an analogue-digital converter, and microcomputers. This system makes it possible to simultaneously analyze the slow-phase velocity quantitatively not only of the horizontal and vertical but also of the rotatory components of the energy-induced nystagmus. The maximum slow-phase velocity of the rotatory component of energy-induced nystagmus was found to be 4.1 degrees per second on an average in this study.

Adult↗

Microcomputer acquisition and analysis system for the isolated working heart preparation.

An automated data acquisition and analysis system based on a microcomputer (Apple II Plus) is described. The system was developed and used to collect and analyze data from rat working heart preparations. The system eases both data acquisition and calculation of derived parameters. Certain sources of error in these calculations are eliminated. The methods and formulae used to obtain various parameters of cardiac function are detailed. In addition, sample data are shown for the effect of thyroid hormone pretreatment on rate of left ventricular pressure development in the rat working heart.

Animals↗

The effect of thigh and goniometer restraints on the reproducibility of the genucom knee analysis system.

We compared the reproducibility of measurements made with the Genucom knee analysis system using two methods of restraint. The first method was that suggested by the manufacturer and consisted of clamping the thigh to the examination chair with 70 N of vertical force and 110 N of mediolateral force and used a single elastic strap to secure the electrogoniometer cuff to the leg. In the second, or enhanced, method, the vertical and mediolateral clamping forces were each increased to 156 N, and an additional strap was used to secure the cuff to the leg. Tests performed were the anteroposterior stress tests at 20 degrees and 90 degrees of knee flexion, and the varus-valgus stress test, the internal-external rotation stress test, and the medial and lateral pivot shift tests at 20 degrees. Five normal subjects were installed and tested on 6 different days with the manufacturer's suggested securing method and on 12 different days with the enhanced securing method. The enhanced method of restraint resulted in significantly reduced day-to-day variance for all tests performed except the varus-valgus stress test.

Adult↗

Profile matching and profile subtraction: application of computer-based image analysis system for two-dimensional electrophoresis gels.

The microcomputer-based image analysis system IB-1000 (developed by Indiana Biotech, Highland, IN) for two-dimensional electrophoresis gels has been described previously (9). It allows the user to compare protein spots between two profiles and identify those spots that are commonly shared in both profiles. This report describes two applications of the system's global comparison routine-profile matching and profile subtraction. This application is able to subtract commonly shared spots from one profile, creating a new profile made up by the unmatched spots in the other profile. These applications can be employed in a large variety of research projects.

Animals↗

[High-performance dynamic ECG review & analysis system].

This paper describes the design of a high-performance dynamic ECG Review & Analysis system used for not only clinical diagnosis but also medical research. A new ECG pattern classifier with Variable Area Template is applied to improve the quantity of ECG analysis results, while the optimized software design ensures the other performances. The results show that this system has higher performance than the old ones and is valuable for medical research.

Computer Systems↗

Application of an anterior eye segment analysis system in clinical cataract research.

Clinical application of a newly developed ANTERIOR EYE SEGMENT ANALYSIS SYSTEM was introduced. By this system, a Scheimpflug and a retroillumination image of the anterior eye segment are obtained through a CCD camera, separately. To overcome difficult problems experienced with previous types of lens documentation systems, several kinds of new mechanisms were built into this system. Slit and retroillumination images of some cases with cataracts and some examples of anterior eye segment analysis were described.

Aged↗

A computer-aided movement analysis system.

Interaction with biomechanical data concerning human movement analysis implies the adoption of various experimental equipments and the choice of suitable models, data processing, and graphical data restitution techniques. The integration of measurement setups with the associated experimental protocols and the relative software procedures constitutes a computer-aided movement analysis (CAMA) system. In the present paper such integration is mapped onto the causes that limit the clinical acceptance of movement analysis methods. The structure of the system is presented. A specific CAMA system devoted to posture analysis is described in order to show the attainable features. Scientific results obtained with the support of the described system are also reported.

Biomechanical Phenomena↗

[Design and implementation of a landscape analysis system based on remote sensing data].

Because of the functions of Geographic Information System(GIS) being not satisfied to the requirements of landscape analysis, a landscape analysis system was designed with Visual C++ and demonstrated with remote sensing data. This system adopted the method f picking-up patch boundary pixel set, improved the patch searching speed, and supplied some landscape analysis functions, such as the calculation of the distance between patches, and the boundary length of neighboring patch, which are not provided by current GIS. It was used to analyzed the landscape of suburbs in northwest Beijing, and the shortcomings of current GIS applied in landscape analysis were overcome.

Algorithms↗