Neonatal behavior and nutrition-related mortality in domestic swine.
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A number of developmental changes occur in eating patterns from infancy through childhood. Initially a primitive reflexive process, deglutition develops into a complex, integrated voluntary/reflexive process. The movements of the tongue, lips and mandible are easily observed to undergo a transformation from synergistic, undifferentiated movements in the infant, to differentiated and refined movements required for biting, chewing, bolus formation and propulsion in the toddler and young child. This transformation is also crucial for the development of higher levels of articulatory precision and coordination required for verbal communication. This developmental process does not always occur in individuals exhibiting orofacial myofunctional disorders. This article will review current research in this area as well as describe how to evaluate for normal tongue, lip and jaw differentiation, and present exercises to develop these skills, which are necessary for successful outcomes in orofacial myofunctional treatment.
Several options are outlined for caring for the slow-gaining breastfed infant when the goal is to continue breastfeeding. A review of pertinent causative factors and simple management solutions are included. Infants with organic causes of slow weight gain can safely be breastfed by using a feeding tube device at the breast. Other feeding options can be explored with the parents, but safety, comfort of the infant, energy conservation, the parents' emotional and time capabilities, and long-term ability to maintain lactation must be considered. A careful follow-up plan is outlined, mostly for encouragement until the problem is corrected and the infant weans himself from the feeding tube if supplementation was required.
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The ability of a preterm infant to make the transition from gavage to oral nipple feeding depends on the infant's neurodevelopment in relation to behavioral organization, to a rhythmic suck-swallow-breathe pattern, and to cardiorespiratory regulation. Research-based knowledge about infant neurodevelopment in these three areas has led to the creation of a semidemand feeding method to aid in this transition. The method combines the use of nonnutritive sucking to promote awake behavior for feeding, use of behavioral assessment to identify readiness for feeding, and systematic observation of and response to infant behavior cues to regulate frequency, length, and volume of oral feedings. Semidemand feeding may be individualized for healthy preterm infants. This article discusses both the relevant knowledge about neurodevelopment and the semidemand feeding method itself.
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We tested the capacity of 2 week postpartum Wistar rat litters and their dams to adapt to experimental shortening and lengthening of the time available for nursing while maintaining the frequency of bouts constant, using manual transfer between cage compartments. In 8-hr and 24-hr experiments, the short bout group (10 min/hr) gradually came to show normal litter weight gain, short latency milk ejections, and increased high arched nursing position, while the 40-min/hr group showed increased latency to attachment and longer latency to ME compared to the 20 min/hr control group. Pup body temperature did not vary between groups. Although pups in the 10-min group showed increased dam-directed behaviors in the first 8h, this difference vanished thereafter. In a twenty-fifth cycle, after dams and litters were exchanged, the prior experiences of the dams and not of the litters were found to determine the dynamics of milk exchange.
Clonidine (0.1 mg/kg), an alpha 2-adrenoceptor agonist, stimulated ultrasonic callings in 10-day-old rats. Unlike normal isolated rat pups, the vocalizations of clonidine-treated rats appeared resilient to maternal cues. Thus, clonidine-induced vocalizations did not decrease during intraoral infusions with 10% sucrose, exposure to home cage bedding or tactile stimulation of the skin. Clonidine (0.05; 0.1; 0.2 mg/kg) also disrupted the attraction normally shown by infant rats to home cage odours in an olfactory place preference test. This effect by clonidine was not shared by raclopride (1-4 mg/kg), naltrexone (0.5-2.0 mg/kg) or propranolol (2.5-10.0 mg/kg). Clonidine-treated infants (0.05; 0.1; 0.2 mg/kg) also failed to apprehend and attach to the anaesthetized mother's nipple. The results raise the possibility that alpha 2-adrenoceptor activation blunts the infant's receptivity to maternal olfactory incentives and intensifies separation-induced responses.
These studies measured changes in blood pressure and heart rates of 15-day-old SHR and WKY rat pups immediately following milk ingestion using three different methods of milk delivery. In the first experiment milk ejections were induced, using IV oxytocin, from the pups' natural mothers, while in the second experiment ejections were elicited from Marland Farms Wistar foster mothers. In the last experiment cow's milk was delivered using tongue cannulas and no mother was present. In each case we found that the dramatic increases in blood pressure associated with milk ingestion were larger in the SHR pups, while heart rate changes tended to be larger in the WKY. We also found that the dynamics of these cardiovascular responses to feeding were significantly altered by the presence of the mother.
These studies provide an animal model for the lithium-induced decrease in suckling reported in the clinical literature that allows for more precise determination of causal mechanisms. Nine-day-old rat pups were administered lithium carbonate via either intraperitoneal (IP) injections or intragastric (IG) gavage in doses approximating that which human infants might receive via breast milk. The pups were tested for their ability to locate and attach to the nipples of an anesthetized dam. Lithium significantly increased the pups' latency to attach to a nipple. Further tests of milk extraction using oxytocin-induced milk-letdowns indicate that lithium also interferes with milk withdrawal. Tests of motor and sensory deficits using an open-field and an olfactory choice test indicated that lithium did not similarly impair these behavioral facets of suckling. Alternative mechanisms for lithium-produced suppression of suckling are discussed.
In 100 bottle-fed preterm infants feeding efficiency was studied by quantifying the volume of milk intake per minute and the number of teat insertions per 10 ml of milk intake. These variables were related to gestational age and to number of weeks of feeding experience. Feeding efficiency was greater in infants above 34 weeks gestational age than in those below this age. There was a significant correlation between feeding efficiency and the duration of feeding experience at most gestational ages between 32 and 37 weeks. A characteristic adducted and flexed arm posture was observed during feeding: it changed along with feeding experience. A neonatal feeding score was devised that allowed the quantification of the early oral feeding behavior. The feeding score correlated well with some aspects of perinatal assessment, with some aspects of the neonatal neurological evaluation and with developmental assessment at 7 months of age. These findings are a stimulus to continue our study into the relationships between feeding behaviour and other aspects of early development, especially of neurological development.
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