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At least 307 records · Page 17Linked to original sources

A simulation model for the analysis of Space Station gas-phase trace contaminants.

A simulation model for the analysis of gas-phase trace contaminants in the cabin air of the NASA Space Station Reference Configuration was developed at the NASA Langley Research Center. The model predicts changes in trace contaminant concentrations from both physical and chemical sources an sinks as a function of time. Simulations were performed in which values for relative humidity, temperature radiation intensity, pressure, and initial species concentrations were constrained to values for the parameters measured and modeled in the continental tropics at the Earth's surface. Species concentrations simulated using the model compared favorable with concentrations in the continental tropics which demonstrated that the chemical mechanism in the trace contaminant model approximates changes atmospheric species concentrations. The sensitivity of initial species concentrations to producing change in additional species concentrations was also assessed. Results from the model indicated that chemical reactions will be important in determining the composition of cabin air in the Space Station. It is anticipated that the trace contaminant model will be useful in assessing the impact of experiments a commercial operations on the composition of the cabin air in the Space Station.

Air Pollutants↗

Functional magnetic resonance imaging activation detection: fuzzy cluster analysis in wavelet and multiwavelet domains.

PURPOSE: To present novel feature spaces, based on multiscale decompositions obtained by scalar wavelet and multiwavelet transforms, to remedy problems associated with high dimension of functional magnetic resonance imaging (fMRI) time series (when they are used directly in clustering algorithms) and their poor signal-to-noise ratio (SNR) that limits accurate classification of fMRI time series according to their activation contents. MATERIALS AND METHODS: Using randomization, the proposed method finds wavelet/multiwavelet coefficients that represent the activation content of fMRI time series and combines them to define new feature spaces. Using simulated and experimental fMRI data sets, the proposed feature spaces are compared to the cross-correlation (CC) feature space and their performances are evaluated. In these studies, the false positive detection rate is controlled using randomization. To compare different methods, several points of the receiver operating characteristics (ROC) curves, using simulated data, are estimated and compared. RESULTS: The proposed features suppress the effects of confounding signals and improve activation detection sensitivity. Experimental results show improved sensitivity and robustness of the proposed method compared to the conventional CC analysis. CONCLUSION: More accurate and sensitive activation detection can be achieved using the proposed feature spaces compared to CC feature space. Multiwavelet features show superior detection sensitivity compared to the scalar wavelet features.

Algorithms↗

Developmental and cross-linguistic variation in the infant vowel space: the case of Canadian English and Canadian French.

This article describes the results of two experiments. Experiment 1 was a cross-sectional study designed to explore developmental and cross-linguistic variation in the vowel space of 10- to 18-month-old infants, exposed to either Canadian English or Canadian French. Acoustic parameters of the infant vowel space were described (specifically the mean and standard deviation of the first and second formant frequencies) and then used to derive the grave, acute, compact, and diffuse features of the vowel space across age. A decline in mean F1 with age for French-learning infants and a decline in mean F2 with age for English-learning infants was observed. A developmental expansion of the vowel space into the high-front and high-back regions was also evident. In experiment 2, the Variable Linear Articulatory Model was used to model the infant vowel space taking into consideration vocal tract size and morphology. Two simulations were performed, one with full range of movement for all articulatory paramenters, and the other for movement of jaw and lip parameters only. These simulated vowel spaces were used to aid in the interpretation of the developmental changes and cross-linguistic influences on vowel production in experiment 1.

Child Language↗

"Aqua-space", a new headspace method for isolation of natural floral aromas using humidified air as a carrier gas.

A new method called "Aqua-space" was developed for the isolation of the natural fragrances of plants. Living flowers were enclosed in a space under simulated natural conditions, and humidified air was pumped into the space as a fragrance carrier. In a comparison among three isolation methods, i.e., Aqua-space, headspace, and solvent extraction, the Aqua-space method proved to be the most effective in retaining natural fragrances with abundant oxygenated components key to floral fragrances.

Air↗

[Intergral criterion and prediction of cosmonauts professional reliability in flight].

Discussed is the problem of professional reliability of cosmonauts simulating manual docking of transport vehicle SOYUZ-TM to space station MIR during acute adaptation to microgravity. A new concept of cosmonaut's reliability qualification is based on the parameters that characterize the systemic body response to job-related factors: integral efficiency and psychophysiological "cost". Justification is given to the statistic methodology of the change-over from prime job quality indices and the functional state of human to integral. Underlined is the possibility to apply this methodical approach to enhancement of the program of assessment and recovery of the professional reliability of cosmonauts in flight.

Adaptation, Psychological↗

Model of human/liquid cooling garment interaction for space suit automatic thermal control.

The Wissler human thermoregulation model was augmented to incorporate simulation of a space suit thermal control system that includes interaction with a liquid cooled garment (LCG) and ventilation gas flow through the suit. The model was utilized in the design process of an automatic controller intended to maintain thermal neutrality of an exercising subject wearing a liquid cooling garment. An experimental apparatus was designed and built to test the efficacy of specific physiological state measurements to provide feedback data for input to the automatic control algorithm. Control of the coolant inlet temperature to the LCG was based on evaluation of transient physiological parameters that describe the thermal state of the subject, including metabolic rate, skin temperatures, and core temperature. Experimental evaluation of the control algorithm function was accomplished in an environmental chamber under conditions that simulated the thermal environment of a space suit and transient metabolic work loads typical of astronaut extravehicular activity (EVA). The model was also applied to analyze experiments to evaluate performance of the automatic control system in maintaining thermal comfort during extensive transient metabolic profiles for a range of environmental temperatures. Finally, the model was used to predict the efficacy of the LCG thermal controller for providing thermal comfort for a variety of regiments that may be encountered in future space missions. Simulations with the Wissler model accurately predicted the thermal interaction between the subject and LCG for a wide range of metabolic profiles and environmental conditions and matched the function of the automatic temperature controller for inlet cooling water to the LCG.

Algorithms↗

Simulation study for cloud detection with space lidars by use of analog detection photomultiplier tubes.

Output signal electrons from photomultiplier tubes (PMTs) have neither a Gaussian nor a Poisson distribution because of changes induced by multiplication when the number of input signal photons and dark electrons is fewer than approximately 100. Therefore the assumption of a Gaussian distribution of signal electrons cannot be used in simulations for space lidar observations with PMTs, for which the number of return signal photons is normally small. A theory is introduced for analog detection with PMTs that have Poisson-distributed secondary-electron emission at each dynode stage. The theory is validated by straightforward numerical simulations. It is shown that the multiplication in PMTs is a multiply stochastic Poisson process and that the distribution of output signal electrons can be interpreted basically as Neyman type A. Analysis by the threshold method of cloud detection with a space lidar shows considerable difference between a Gaussian approximation and the exact distribution. The result indicates that the threshold level must be optimized for the exact distribution. Return signals were simulated for a proposed space lidar, and cloud detection with the threshold method was demonstrated.

Journal Article↗

Leadership issues with multicultural crews on the international space station: lessons learned from Shuttle/Mir.

In isolated and confined environments, two important leadership roles have been identified: the task/instrumental role (which focuses on work goals and operational needs), and the supportive/expressive role (which focuses on morale goals and emotional needs). On the International Space Station, the mission commander should be familiar with both of these aspects of leadership. In previous research involving a 135-day Mir space station simulation in Moscow and a series of on-orbit Mir space station missions during the Shuttle/Mir program, both these leadership roles were studied. In new analyses of the Shuttle/Mir data, we found that for crewmembers, the supportive role of the commander (but not the task role) related positively with crew cohesion. For mission control personnel on the ground, both the task and supportive roles of their leader were related positively to mission control cohesion. The implications of these findings are discussed in terms of leadership on board the International Space Station.

Adult↗

Thermodynamic and kinetic characterization of a beta-hairpin peptide in solution: an extended phase space sampling by molecular dynamics simulations in explicit water.

The folding of the amyloidogenic H1 peptide MKHMAGAAAAGAVV taken from the syrian hamster prion protein is explored in explicit aqueous solution at 300 K using long time scale all-atom molecular dynamics simulations for a total simulation time of 1.1 mus. The system, initially modeled as an alpha-helix, preferentially adopts a beta-hairpin structure and several unfolding/refolding events are observed, yielding a very short average beta-hairpin folding time of approximately 200 ns. The long time scale accessed by our simulations and the reversibility of the folding allow to properly explore the configurational space of the peptide in solution. The free energy profile, as a function of the principal components (essential eigenvectors) of motion, describing the main conformational transitions, shows the characteristic features of a funneled landscape, with a downhill surface toward the beta-hairpin folded basin. However, the analysis of the peptide thermodynamic stability, reveals that the beta-hairpin in solution is rather unstable. These results are in good agreement with several experimental evidences, according to which the isolated H1 peptide adopts very rapidly in water beta-sheet structure, leading to amyloid fibril precipitates [Nguyen et al., Biochemistry 1995;34:4186-4192; Inouye et al., J Struct Biol 1998;122:247-255]. Moreover, in this article we also characterize the diffusion behavior in conformational space, investigating its relations with folding/unfolding conditions.

Computer Simulation↗

Telescience testbed: operational support functions for biomedical experiments.

A telescience testbed was conducted to study the methodology of space biomedicine with simulated constraints imposed on space experiments. An experimental subject selected for this testbedding was an elaborate surgery of animals and electrophysiological measurements conducted by an operator onboard. The standing potential in the ampulla of the pigeon's semicircular canal was measured during gravitational and caloric stimulation. A principal investigator, isolated from the operation site, participated in the experiment interactively by telecommunication links. Reliability analysis was applied to the whole layers of experimentation, including design of experimental objectives and operational procedures. Engineering and technological aspects of telescience are discussed in terms of reliability to assure quality of science. Feasibility of robotics was examined for supportive functions to reduce the workload of the onboard operator.

Aerospace Medicine↗

Organization, selection, and training of crews for extended spaceflight: findings from analogs and implications.

Ample research evidence from space analogs points to the crucial role that teamwork plays in the performance of small groups in isolation and confinement. This paper surveys findings about the impacts of group behavior and social interaction on crew morale, coordination, and productivity. Implications for the organization, selection, and training of crews for extended spaceflight are discussed.

Astronauts↗

Overview of NASA's space radiation research program.

NASA is developing the knowledge required to accurately predict and to efficiently manage radiation risk in space. The strategy employed has three research components: (1) ground-based simulation of space radiation components to develop a science-based understanding of radiation risk; (2) space-based measurements of the radiation environment on planetary surfaces and interplanetary space, as well as use of space platforms to validate predictions; and, (3) implementation of countermeasures to mitigate risk. NASA intends to significantly expand its support of ground-based radiation research in line with completion of the Booster Applications Facility at Brookhaven National Laboratory, expected in summer of 2003. A joint research solicitation with the Department of Energy is under way and other interagency collaborations are being considered. In addition, a Space Radiation Initiative has been submitted by the Administration to Congress that would provide answers to most questions related to the International Space Station within the next 10 years.

Cosmic Radiation↗