Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Retinal Telangiectasis”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 307 records · Page 17Linked to original sources
PubMed1983

Familial exudative vitreoretinopathy.

Two sisters and a brother with the syndrome of familial exudative vitreoretinopathy are described (FEV). Findings associated with this condition include temporal neovascularization, vitreous hemorrhage, and retinal detachment. Familial exudative vitreoretinopathy is a genetic syndrome with nearly complete penetrance but widely variable expressivity. The differential diagnosis is fairly extensive. This condition is sometimes confused with retrolental fibroplasia, and FEV is probably a more frequently occurring disease than previously thought, because of confusion with RLF. The pathophysiologic mechanism, natural history, and optimal treatment of this disease are matters of debate. With active surgical management, three of the four eyes which presented to us for treatment have visual acuity of 20/30 or better.

Child↗
PubMed1977

Coats' disease.

Explore the source record for details and available documents.

Adolescent↗
PubMed1997

Proton MR spectroscopy in Coats disease.

We describe a case of acute left-sided visual loss in a 4-year-old boy. CT showed hyperdense retinal detachment with a tiny calcification, and MR imaging showed subretinal hyperintensity on both T1- and T2-weighted images. Proton MR spectroscopy showed a large peak between 1 and 1.6 ppm that we believe corresponds mainly to lipids, which are characteristic of the exudate present in Coats disease.

Blood-Retinal Barrier↗
PubMed1999

Histopathologic study of presumed parafoveal telangiectasis.

PURPOSE: To report the postmortem histopathologic features that closely resemble the clinical features of parafoveal telangiectasis. METHODS: Light and electron microscopy. RESULTS: Histopathologic features included macular edema; telangiectatic vessels; retinal, subretinal, and superficial retinal neovascularization; retinal pigment epithelial hyperplasia around neovascular aggregates; retinal-choroidal vascular anastomosis; and superficial pigmented cells with lipofuscin. CONCLUSION: The postmortem histopathologic findings in a 36-year-old woman with Down syndrome and other systemic conditions correlate with features noted in previous reports of presumed parafoveal telangiectasis.

Adult↗
PubMed1996

Macula toxicity after intravitreal amikacin.

BACKGROUND: Although intravitreal aminoglycosides have substantially improved visual prognosis in endophthalmitis, macular infarction may impair full visual recovery. METHODS: We present a case of presumed amikacin retinal toxicity following treatment with amikacin and vancomycin for alpha-haemolytic streptococcal endophthalmitis. RESULTS: Endophthalmitis resolved with improvement in visual acuity to 6/24 at three months. Fundus fluorescein angiography confirmed macular capillary closure and telangiectasis. CONCLUSIONS: Currently accepted intravitreal antibiotic regimens may cause retinal toxicity and macular ischaemia. Treatment strategies aimed at avoiding retinal toxicity are discussed.

Adolescent↗
PubMed1997

Ocular findings in cutis marmorata telangiectatica congenita. Bilateral exudative vitreoretinopathy.

BACKGROUND: Cutis marmorata telangiectatica congenita is a rare, cutaneous, reticulated, vascular anomaly characterized by congenital persistent cutis marmorata, telangiectasis, and phlebectasis. While systemic abnormalities frequently are associated with cutis marmorata telangiectatica congenita, ophthalmic abnormalities are quite rare and include congenital glaucoma and congenital, bilateral, total retinal detachments with secondary glaucoma. METHODS: The authors report a case of bilateral, tractional retinal detachments associated with peripheral fibrovascular proliferation simulating familial exudative vitreoretinopathy in a female child with cutis marmorata telangiectatica congenita. Molecular genetic analysis of the Norrie's disease gene was performed. RESULTS: After vitrectomy, the posterior poles of both eyes were reattached successfully. No abnormalities of the Norrie's disease gene were identified. CONCLUSIONS: Bilateral exudative vitreoretinopathy is a rare ophthalmic manifestation associated with cutis marmorata telangiectatica congenita.

Child, Preschool↗
PubMed2004

Lack of apparent short-term benefit of photodynamic therapy in bilateral, acquired, parafoveal telangiectasis without subretinal neovascularization.

PURPOSE: To analyze the results of photodynamic therapy (PDT) in bilateral acquired parafoveal telangiectasis. DESIGN: Interventional cases report. METHOD: Retrospective analysis of visual acuity measured with ETDRS charts and of fluorescein angiography findings for two women in whom the eye with lesser visual acuity was treated by PDT for bilateral acquired parafoveal telangiectasis without subretinal neovascularization. RESULTS: Initial visual acuity of the treated eye was 20/63 in both patients and did not change significantly for 3 to 6 months after one session of PDT. Fluorescein angiography in both cases and optical coherence tomography in one case also appeared unchanged. No adverse effect has been observed. CONCLUSIONS: Photodynamic therapy was not beneficial for the outcome of these patients with bilateral acquired telangiectasis, because it improved neither their visual acuity nor their macular edema.

Adult↗
PubMed1995

[Idiopathic juxtafoveolar telangiectasis. Long-term follow-up of visual acuity].

The beneficial effect of laser therapy on idiopathic juxtafoveolar telangiectasis is questionable. We therefore studied retrospectively the spontaneous course of the disease and tried to show a correlation between the initial angiographic findings and visual outcome. In addition, the results after laser therapy were compared with untreated patients. Thirteen patients (24 eyes) with idiopathic juxtafoveolar telangiectasis diagnosed by fluorescein angiography were reexamined after a mean time interval of 38 months. Argon laser coagulation had been performed in 6 patients. The initial extension of fluorescein leakage was divided angiographically into three different stages. The existence of secondary macular changes and peripheral involvement was noted. The mean visual acuity decreased from 0.71 to 0.62 over the follow-up period. No correlation could be found between the final visual outcome and initial extension of telangiectasis or existence of secondary changes. After laser coagulation the patients did not show a better visual outcome. Due to the relatively benign spontaneous course of idiopathic juxtafoveolar telangiectasis laser coagulation cannot be recommended in general. Only in exceptional cases (e.g., development of subretinal neovascularization) can laser coagulation be of benefit.

Aged↗
PubMed2002

Neovascular membranes associated with idiopathic juxtafoveolar telangiectasis.

OBJECTIVE: To report the visual outcome in patients with a neovascular membrane (NVM) associated with idiopathic juxtafoveolar telangiectasis (IJFT). METHODS: We performed a retrospective, noncomparative analysis of 26 eyes of 16 patients with an NVM associated with bilateral IJFT (Gass classification group 2A). Eyes were divided into 2 groups: group WO (n = 11) included eyes with IJFT without evidence of an NVM on initial examination; eyes in group W (n = 15) had an NVM at the initial diagnosis of IJFT. In group WO, the initial visual acuity and the time between the initial examination to the diagnosis of an NVM were evaluated. Characteristic fundus findings, including the presence or absence of a chorioretinal anastomosis, intraretinal pigmentary plaques, and crystalline deposits, as well as the final visual acuity were reviewed for both groups. RESULTS: The initial visual acuity for eyes in group WO ranged from 20/20 to 20/70 (median, 20/30); in group W, from 20/20 to 4/200 (median, 20/70). The average time from initial diagnosis of IJFT to the development of an NVM was 73 months (range, 5-142 months). In group WO, chorioretinal anastomosis and concurrent perivascular retinal pigment epithelial hyperplasia were observed before the development of an NVM. The final visual acuity for all eyes ranged from 20/40 to 2/200 (median, 20/200). Eighty-one percent of eyes (21/26) had a final visual acuity of 20/200 or worse. CONCLUSIONS: The stable final visual acuity in patients with an NVM associated with IJFT is generally poor, with 80% of eyes in this series having a final visual acuity of l20/200 or worse. In patients with IJFT, the presence of a chorioretinal anastomosis and retinal pigment epithelial hyperplastic plaques always preceded the development of an NVM.

Adult↗