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Calcium hydroxylapatite for facial rejuvenation.

Porous calcium hydroxylapatite has been used in otolaryngology, dentistry and radiology for many years. Currently, calcium hydroxylapatite is gaining popularity for facial esthetics in the form of the product Radiesse (San Mateo, CA). Although Radiesse is not yet approved in the United States for cosmetic use, it is being used off-label by an increasing number of dermatologists and plastic surgeons for facial soft-tissue augmentation. Preliminary clinical and histologic studies have shown safety, efficacy and durability in various esthetic applications including the nasolabial folds and HIV lipoatrophy.

Biocompatible Materials↗

The use of injectable collagens for aesthetic rejuvenation.

Bovine collagen was approved by the Food and Drug Administration in 1982 and since that time has remained a primary filler of choice for soft-tissue augmentation of dermal defects. During the past decade, however, perhaps mirroring the growth and overwhelming acceptance of botulinum toxin for wrinkle reduction, there has been an increase in demand and availability of new injectable filler products. A partial list includes the ever-expanding class of hyaluronans (hyaluronic acids), calcium hydroxylapatite, polymethylmethacrylate, poly-L-lactic acid, and silicone oil. There are many more on the immediate horizon that are under investigation both abroad and in the United States. Nevertheless, the collagen family of agents, regardless of their source of derivation, remain a reliable and useful alternative. They have an unparalleled record of safety and efficacy; they have different formulations, which makes them amenable to many indications and user friendly for the physician. And, for patient, the admixture of local anesthesia reduces the discomfort of the injection procedure.

Biocompatible Materials↗

'Dr Steinach coming to make old young!': sex glands, vasectomy and the quest for rejuvenation in the roaring twenties.

In the 1920s, research on the endocrine glands--especially the sex glands--was widely expected to lead to revolutionary new ways of improving human life. The medical marketplace was crowded with glandular techniques to revitalize the aged. 'Monkey glands' apart, the Austrian physiologist Eugen Steinach's simple, vasectomy-like operation was perhaps the most popular of these. Steinach was one of the leading endocrine researchers of the early 20th century and the Steinach Operation was based on rigorous laboratory research. It was much more than a simple scientific error, and its history shows us how early endocrine research was shaped by broader social and cultural forces.

Aging↗

Relevant anatomy for botulinum toxin facial rejuvenation.

Over the last several years, Botox has become an integral treatment modality in the management of facial aging. Through selective chemical denervation, rhytids that are associated with hyperfunctioning muscles can be considerably softened or eliminated. Most practitioners rely on surface anatomy and landmarks to guide accurate needle insertion and Botox therapy. Therefore, a detailed appreciation of the underlying muscular anatomy is paramount in improving the practitioner's cosmetic results and the patients' overall satisfaction.

Botulinum Toxins, Type A↗

[Facial surgery for rejuvenation].

Aging brings about anatomical changes that are undesirable. Senescence is consequently one of the most powerful stimuli for aesthetic surgery. The face, responsible for the myriad expressions of human experience, is constantly subject to exposure and also suffers from the perennial action of environmental factors and gravity. Frequently, the face is the main focus of anxiety in individuals who have attained a certain age, presenting skin flaccidity and loss of tone, marked lines of expression and fat deposits. Expectations of both the patient and the surgeon, regarding facial aesthetic surgery, have increased considerably over the last two decades with the advent of newer procedures and equipment. While experience allows the surgeon a better selection of techniques, at the same time he must be knowledgeable in details of different surgical approaches and variations to attain the best result for each individual case. The anatomy of the aging face should be examined carefully for a personalized treatment plan. Currently, a satisfactory result of an aesthetic facial procedure is obtained when signs of an operation are undetectable and no anatomical landmarks have been altered. The bond created between the patient and surgeon will be frustrated if there remain signs that reveal the "secret" that surgery was performed.

Adipose Tissue↗

Long-term results of facial rejuvenation by carbon dioxide laser resurfacing using a quantitative method of assessment.

Carbon dioxide laser resurfacing has been widely reported as an effective method for treating facial rhytides. Few published series, however, have assessed the long-term results of this procedure. We prospectively reviewed our long-term results of perioral CO(2) laser resurfacing using an accurate, reproducible and quantitative method of evaluation. Wrinkle depth was measured using a silicone elastomer to provide an exact negative-replica mask of the perioral region. Simple light microscopy was then used to measure the depth of rhytides. This was carried out preoperatively, 6 weeks postoperatively and 2 years postoperatively, and the results were compared for 31 patients. CO(2) laser resurfacing achieved a highly significant mean reduction in wrinkle depth at 6 weeks of 91% (paired t -test:P <0.00001), and this was well maintained at 2 years, when the mean reduction in wrinkle depth was 87% (paired t-test: P<0.00001). During the long follow-up, complications were few, with transient erythema being the most common; there were no cases of scarring. As in other series that have reported longer follow-up, we encountered three cases of minor hypopigmentation. We have used light microscopy on silicone moulds as an accurate method of assessing outcome after laser resurfacing of perioral rhytides. The early highly significant reduction in wrinkle depth was maintained at 2 years with minimal associated short-term or long-term morbidity.

Aged↗

Botulinum A exotoxin for rejuvenation of the upper third of the face.

Botulinum A exotoxin, derived from the gram-positive anaerobe Clostridium botulinum, has proven to be safe and effective in the temporary treatment of facial rhytides. In order to obtain reproducible results and avoid complications, it is necessary to understand the relevant physiology and anatomic relationships. Technical considerations including injection technique, dilution, storage, and potential complications will be discussed.

Blepharoptosis↗

Importance of chin evaluation and treatment to optimizing neck rejuvenation surgery.

The chin is the keystone linking the aesthetics of the face and neck but is often neglected in the analysis. Procedures related to the chin play an important role in defining neck anatomy. Alloplastic implants can provide the illusion of a longer jaw line in a patient with retrogenia. Even greater anatomic changes to the neck result when a sliding genioplasty is performed. This effect is primarily due to the digastric attachments from the mentum and mastoid. Advancing the mentum may have a more direct effect of elevating the position of the hyoid, which sharpens the angle between the jaw and neck. Finally, the diagnosis of a witch's chin is also discussed for the patients who present for aging neck surgery.

Chin↗

Pitfalls of photography for facial resurfacing and rejuvenation procedures.

Photography's role in documenting changes after aesthetic surgical procedures is well established. Facial resurfacing procedures usually cause subtle changes in skin topography. Capturing these objective photographic differences necessitates an understanding of basic photographic principles pertinent to accurately documenting photographic changes. Variables examined include lighting, exposure, aperture, camera type, white balance, lens focal length, and patient positioning. A set of suggested guidelines for accomplishing these goals is given for the facial plastic surgeon.

Cosmetic Techniques↗

Anatomic and aesthetic considerations in midfacial rejuvenation.

An early sign of the aging process involves changes to the midface. The loss of the lid-cheek continuum begins with underlying laxity in the orbitomalar ligament. As the face continues to age, the malar pad drops inferomedially in position. The approach to the midface has evolved over the past 15 years with the advent of endoscopically assisted techniques of midfacial elevation. Further technology, such as thread-lifting procedures and the Endotine Midfacetrade mark, have supplemented the choices for surgical correction of this facial segment. Descriptions of the different approaches to the aging midface are reviewed.

Adipose Tissue↗

Skin rejuvenation in facial surgery.

The treatment of the aging face has evolved to increasingly incorporate minimally office-based procedures. The importance of recognizing and treating facial rhytids has always been recognized as important, but an increasing number of modalities have been developed for this purpose. Similarly, there has been an increase of emphasis in the recognition of dyschromias, solar keratoses, and other skin abnormalities. In this article, an overview of many of the minimally invasive office-based procedures that we favor in our practice will be briefly reviewed.

Botulinum Toxins, Type A↗

Surgical rejuvenation of the brow and forehead.

The position and orientation of eyebrows plays an important part in the overall appearance of the face. Many incisions and approaches have been described to elevate a ptotic eyebrow. It is essential to understand the periorbital anatomy and the biomechanics of elevation and fixation of the brow and forehead soft tissues. If properly planned and executed, surgical brow lifts can restore a youthful appearance to eyelids and the orbit.

Biomechanical Phenomena↗

Combination therapies in oculofacial rejuvenation.

The oculo-facial surgeon's quest for non-invasive procedures is a response to increasing patient demands for enhanced results without any downtime. Technology has obliged us with multiple injectable and light therapeutic modalities that tighten skin, relax and fill in wrinkles, and improve skin dyspigmentation and texture. When these techniques are combined, the results are superior to the use of individual therapies alone. The foundation for combination therapies are: botulinum toxin, filling agents, chemical peels, intense pulsed light, non-ablative and ablative lasers.

Blepharoplasty↗