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PubMed2004

HASTE MRI versus chest radiography in the detection of pulmonary nodules: comparison with MDCT.

OBJECTIVE: The purpose of our study was to compare the diagnostic accuracy of an ultrafast ECG-triggered black blood-prepared HASTE sequence with chest radiography for the detection of pulmonary nodules. SUBJECTS AND METHODS. Sixty-four patients with various primary malignancies who had undergone radiography and MDCT of the chest also underwent ECG-triggered black blood-prepared HASTE MRI of the lung. MR images and radiographs were interpreted separately. The number, location, and size of detected lesions were recorded, and each hemithorax was classified as affected or not affected on the basis of a grade reflecting the conspicuity of nodular involvement. Sensitivity, specificity, and positive and negative predictive values for the detection of pulmonary nodules with diameters of 5 mm or larger were determined, using MDCT findings as the standard of reference. Lesions with diameters smaller than 5 mm were not evaluated. Additional lesion-by-lesion comparisons between MDCT and MRI findings were performed. RESULTS: MDCT confirmed pulmonary lesions in 32 patients, whereas HASTE MRI revealed lesions in 30 patients and chest radiography, in 19 patients. MDCT revealed 226 nodules in 32 patients, whereas MRI HASTE revealed 227 lesions in 30 patients. Conspicuity scale-based sensitivity and specificity for chest radiography were 55.8% and 92.4%, respectively, whereas HASTE MRI had a sensitivity of 93.0% and a specificity of 96.2%. Positive and negative predictive values for chest radiography were 80% and 79.3%, respectively, and for HASTE MRI, 93.0% and 96.2%, respectively. The sensitivity of HASTE MRI increased with lesion size, ranging from 94.9% for nodules between 5 and 10 mm in diameter to 100% for lesions exceeding 3 cm in diameter. CONCLUSION: ECG-triggered black blood-prepared HASTE MRI is reliable for detecting pulmonary nodules exceeding 5 mm and has proven significantly more accurate than conventional chest radiography. The technique appears useful as an adjunct to MRI of the heart, great vessels, or chest, potentially increasing the diagnostic yield of MRI examinations.

Electrocardiography↗
PubMed1989

[Digital subtraction radiography for the detection of periodontal bone changes].

This study was performed to evaluate the efficacy of digital subtraction radiography in detecting alveolar bone changes. In order to test the sensitivity of quantitative evaluation by subtraction radiography, a copper equivalent thickness obtained from digitized radiographs was compared with the actual mineral content of bone phantoms with 15 different minerals and 25 bone specimens. Results demonstrated that the copper equivalent thickness correlated well with the actual mineral content (bone phantoms: gamma s = 1.0, bone specimens: gamma s = 0.985). In order to test the ability of digitized subtraction radiography in assessing alveolar bone changes in vivo, subtraction images were compared with histological features. The experimental angular bony defects were treated with conservative periodontal therapy in 3 monkeys. The standardized radiographs were taken longitudinally after therapy, and subtraction images were made from the sequentially obtained radiographs. In addition, for fluorescent histomorphometrical evaluations of new bone formations, the animals were dosed with oxytetracycline, calsein solution and arizarin complex solution. Radiographic and histological evaluations were scheduled to provide healing periods of 2, 3, 4, 5, 6 and 9 weeks after periodontal therapy. Subtraction radiography offered an objective method to follow histological changes of alveolar bone, and the copper equivalent thickness obtained from subtraction radiographs correlated with the histometric bone volume (gamma s = 0.9023, p less than 0.01). The results of these studies indicated that subtraction radiography was useful in monitoring alveolar bone changes associated with periodontal disease and treatment and that the quanitative measurement of periodontal bone changes by subtraction radiography was feasible.

Alveolar Process↗
PubMedDate not supplied

Role of upright chest radiography and ultrasonography in demonstrating free air of perforated peptic ulcers.

BACKGROUND/AIMS: The purpose of this study was to determine the value of upright chest radiography and ultrasonography in demonstrating free air of perforated peptic ulcers. METHOLOGY: Eighty-four patients with perforated peptic ulcers receiving both upright chest radiography and ultrasonography before laparotomy. The sensitivity of each modality in demonstrating free air was correlated. RESULTS: Among the 84 patients receiving both examinations, free air was demonstrated in only 39 (46%) upright chest radiographs and 46 (55%) ultrasonographs, the direct sign could be demonstrated in 57 (68%) patients by combined radiography and ultrasonography. Besides, the indirect sign of ascites could be demonstrated in 26 (31%) ultrasonographs. CONCLUSIONS: Ultrasonography is more sensitive than upright chest radiography to demonstrate free air of perforated peptic ulcers, and it should be considered in those patients of suspected perforated peptic ulcers with negative upright chest radiography. Combined methods of upright chest radiography and ultrasonography can increase the overall sensitivity in demonstrating free air.

Adolescent↗
PubMed1991

[Digital thoracic radiography--a comparison of digital and analog imaging techniques].

New analog and digital imaging techniques for the chest became available in recent years. In this study conventional film/screen radiography was compared with slit technique ('AMBER'), storage phosphor radiography and digital image intensifier radiography by phantom exposures and patient examinations. Because of its low spatial resolution, quality of digital image intensifier radiography was insufficient for chest imaging. The slit technique demonstrated the highest image quality, especially in the fields of the mediastinum and the thoracic wall. In comparison to conventional film/screen radiography, storage phosphor radiography had advantages in the mediastinal field. Digital techniques are connected to new possibilities of image post-processing, storage and transfer. For difficult conditions of exposure (emergency unit) over- or underexposed images can be avoided by these new digital techniques. The combination of slit- and storage phosphor-technique did not increase image quality.

Analog-Digital Conversion↗
PubMed1987

The current status of panoramic radiography.

The current status of dental panoramic tomography (rotational panoramic radiography) is reviewed. This technique is based on a combination of tomography and slit-beam radiography to provide an image of both jaws on a single film. There is a greater degree of image degradation when compared with conventional radiographic techniques due to tomographic blurring, magnification and distortion, secondary images and burn-out. Meticulous patient position is essential to accommodate their jaws to the image layer determined by the manufacturers. The absorbed doses from panoramic radiography are of a similar order to that from bitewing radiography and lower than those from a full-mouth periapical series. The individual risk of 1.3 X 10(-6) is compared with that from other radiographic examinations and smoking. The collective risk, 1.04 deaths in the UK in 1981, is relatively insignificant as is the genetic dose. The risk to the dentist and his staff is also low compared to other risks. The methods of dose limitation currently available are reviewed. The clinical indications are considered in relation to the guidelines of the American Dental Association and the Dental Estimates Board in the UK. The problems associated with attempts to measure diagnostic yield are considered. In view of the world-wide public concern at the potential dangers of ionising radiation, dentists are urged to maximize the diagnostic yield from their panoramic radiography by taking such radiographs only when clinically necessary, ensuring meticulous positioning and processing, followed by scrupulous assessment of the radiography for any sign of pathological change.

Humans↗
PubMedDate not supplied

[Thoracic radiography in occupational health examination of hospital personnel. Making decisions].

BACKGROUND: The routine chest radiography has been legally suppressed because of its low diagnostic profitability in non selected populations. Health surveillance of occupational populations at respiratory risk is entering a transitional period, where new guidelines are needed. Therefore, we determined to study the percentage of pathological findings in the chest radiographies of health examinations for hospital workers and whether it was possible to obtain explicative models allowing to calculate the probability of radiographies alteration. METHODS: A representative stratified sample of workers belonging to the Hospital La Paz in Madrid is studied, elaborating a transversal study based on the first health examination of their clinical history and two chest radiographies of further examinations. We carried out a multivariant analysis to calculate the probability of their alteration. RESULTS: We obtain alterations percentages of 19% for the first chest radiography; 23.5%, 22% and 21% for the two further ones and for the total, respectively. The explicative models obtained are based on age, family and personal antecedents of the respiratory disease, number of cigarettes smoked, cholesterol levels, the Mantoux test and the previous radiographies alteration. CONCLUSIONS: These equations may be an additional instrument together with labour environment considerations and within a clinical context, to help to the health specific occasional surveillance of the respiratory risk of hospital personnel.

Adult↗
PubMed1993

[The use of thoracic radiography in a third-level-care pediatric hospital].

OBJECTIVES: 1. To describe the frequency in which the thorax radiography is requested in a third-level pediatric hospital, 2. To identify the frequency of detected abnormalities in such a study by the radiology service, 3. To describe the frequency and the characteristics form the information considered as useful in a clinical way, not only in the radiography application but in the radiologic report and the clinical file as well, 4. To identify the frequency in which the thorax radiography result is associated with diagnosis changes and/or therapeutic ones. DESIGN OF THE INVESTIGATION: Descriptive survey. STUDY UNITS: 371 thorax X-rays completed during December 1990 and January 1991. PRIMARY RESULTS: The thorax radiographies were 32% of the entire radiological study during the survey; 335 of the latter ones (90%) were requested for inpatients. The hospital services which had the highest request for such a study were the Intensive Care Unit (n = 149, 40%) and Medical Pediatrics (n = 116, 31%). The most frequent diagnosis leading to the application was pneumonia (n = 55, 15%) and solid neoplasia (n = 51, 14%). Three-hundred forty eight of the applications had diagnostic impression given by the physician in charge(94%); whereas only 127 (34%) mentioned clinical data. The radiology report was attached to the file in 162 (44%) of the cases. It was found that form the patients who had a radiology report and the thorax radiography as an initial study (n = 95), 48 (50%) suffered from abnormalities. The results of the study were transcribed in the file in 58 cases (16%); the physician's interpretation was written down in 229 cases (62%) and in 84 studies (23%) there was no reference to the results of the study (P < 0.0001). Changes in the therapeutic plan of 93 cases (50%) were identified from the studies with official report by the radiologist, other radiology studies were requested in 65 of the patients (35%), after the interpretation of such study. CONCLUSIONS: Abnormalities in 50% were identified from the total thorax radiographies requested as the patient entered. The study application mentioned as a whole (94%) the diagnostic impression which led to the application, but only in 127 cases (34%) were supporting clinical data written down. The radiology report was attached to the file in less than half the cases (44%). In 63% of the cases the supporting reason of the study was written down whereas in 23% there was no reference to the result at all.

Adolescent↗
PubMed2005

Accuracy of radiography in grading and tissue-specific diagnosis--a study of 200 consecutive bone tumors of the hand.

OBJECTIVE: To determine the usefulness of radiography and magnetic resonance imaging in differentiating benign from malignant bony tumors of the hand and in making a tissue-specific diagnosis. DESIGN: Two hundred consecutive bony tumors of the hand, the details of which originated from a national databank, were studied in a prospective way by radiography (100%) and by MRI (25%). All tumors were graded on a five-point scale, from certainly benign to certainly malignant, using location and morphology as diagnostic parameters. For all tumors a tissue-specific diagnosis was made, by the proposal of three possibilities in decreasing order of probability. Histological diagnosis was made by peer review, according to the WHO classification. RESULTS: By the combining of "certainly" and "probably" benign (grades I and II) and "certainly" and "probably" malignant (grades IV and V), a correct grading was obtained in 165 (82.5%) of the cases (154 of the 173 benign and 11 of the 27 malignant tumors). A correct tissue-specific diagnosis was included in the three proposed differentials in 87.5%. MRI confirmed a correct diagnosis made on radiography in 72% and improved the grading capability by correctly upgrading malignant tumors and downgrading benign tumors in, respectively, 8% and 12%. The capability to obtain a tissue-specific diagnosis improved with change of an incorrect diagnosis on radiography to a correct one on MRI in 12 cases (24%). CONCLUSION: Subjective (semiquantitative) grading on radiography by an expert group proved to be excellent when compared with the results of a quantitative analysis of individual grading parameters. Multiple logistic regression analysis of these parameters resulted in a grading formula containing only six variables. The additional value of MRI in grading was amply demonstrated. Already high accuracy of radiography, in making a tissue-specific diagnosis, improved substantially after the performance of MRI.

Adult↗
PubMedDate not supplied

Current status of small bowel radiography.

BACKGROUND: In the past, small bowel examinations were usually ordered for the sake of "completeness." As a result, small bowel radiography was performed casually and without attention to detail. This review examines pertinent clinical issues and the recent contribution of small bowel radiography to the evaluation and management of the patient with suspected small bowel disease. Recommendations for the clinical utilization of small bowel radiography are discussed. METHODS: Analysis of pertinent citations addressing valid indications for, and technique of, small bowel radiography from 1980 to July 1995 through a computerized bibliographic search (Medline and Current Contents). RESULTS: Accepted clinical indications for small bowel radiography include (1) unexplained gastrointestinal bleeding, (2) possible small bowel tumor, (3) small bowel obstruction, (4) Crohn disease, and (5) malabsorption. The current literature reflects the limitations of the conventional small bowel follow-through, various modifications to improve its clinical yield, the important contribution of enteroclysis in the workup, and subsequent management of patients with possible small bowel disease. A controversy in the radiology literature exists as to whether to use the small bowel follow-through or enteroclysis as the primary method of examining the small bowel. CONCLUSION: The thoughtful selection of patients by clinicians for small bowel radiography is essential to make radiologic evaluation cost effective. The incidence of disease of the small intestine is low and is associated with nonspecific symptoms. Because of the inherent difficulty of visualizing numerous loops of an actively peristalsing bowel, a reliable imaging method is needed that not only detects small or early structural abnormality but also accurately documents normalcy. The yield of information provided by enteroclysis and its high negative predictive value suggests that it should be the primary method for small bowel examination. The "overhead"-based conventional small bowel follow-through should be abandoned. The "fluoroscopy"-based small bowel follow-through augmented when necessary by the peroral pneumocolon or the gas-enhanced double-contrast follow-through method is an acceptable alternative when enteroclysis is not possible.

Crohn Disease↗
PubMed1999

[The demonstration of microcalcification in breast core biopsies: DIMA specimen radiography (7x) compared to the histopathological findings].

PURPOSE: Comparing the sensitivity in detecting microcalcifications in stereotactically guided core biopsy specimen of the breast of direct magnification (DIMA) specimen radiography (x7) with the histological examination. MATERIALS AND METHODS: In 52 patients 509 stereotactically obtained core biopsy (14-gauge) specimens of the breast were radiographed by direct magnification (DIMA) specimen radiography (x7) and examined histologically. RESULTS: In 188 specimen microcalcifications were detected by magnification radiography compared to 98 by histological examination. Only 3% of the specimen microcalcifications were seen exclusively in the histological examination. In core biopsies with malignancy the relative proportion of biopsies with radiologically detected microcalcifications was increased (59% versus 32%). CONCLUSION: Concerning the detection of microcalcifications in core biopsy specimen of the breast, the direct magnification (DIMA) radiography (x7) was superior compared to the histological examination. Due to the high relative proportion of biopsies with radiologically detected microcalcification and malignancy, we recommend a comprehensive histological examination of these specimen. Confirmation of microcalcifications in core biopsies should be achieved by magnification radiography to prove that the suspicious area in the breast was truly sampled. Specimen radiography simultaneously with the biopsy procedure can reduce the number of punctures in the process of documenting the presence of calcifications early in the biopsy procedure.

Biopsy↗
PubMed1989

[Digital image intensifier radiography--one year's experience with a Polytron system].

Since January 1988, digital image intensifier radiography has been used in the Clinic in Mannheim for DSA examinations and also in place of conventional screen/film examinations. Measurements have shown that compared with 100 mm and film/screen formats, digital radiography has poorer spatial resolution, but improved contrast resolution. The most common use of digital radiography was for examinations of the gastrointestinal tract. Using the demonstration of the mucosal fine relief pattern as a criterion of image quality, digital image intensifier radiography was able to achieve this satisfactorily. Comparison with film/screen examinations showed no loss of diagnostic information. Advantages of image intensifier radiography are reduced radiation dose, the possibility of postprocessing and economy. On the basis of 399 examinations, digital image intensifier radiography is now firmly established as part of the daily routine of the Mannheim Clinic.

Evaluation Studies as Topic↗
PubMed1988

Quantitative digital radiography versus dual photon absorptiometry of the lumbar spine.

Lumbar spine bone mineral density (BMD) was measured by quantitative digital radiography, a new dual energy x-ray technique, and by 153Gd dual photon absorptiometry (DPA) in 85 patients. Each patient was measured twice by the new method and once by DPA on the same day, with repositioning between measurements. Serial measurements were made on an hydroxyapatite spine phantom embedded in tissue-equivalent plastic to evaluate the long term reproducibility of each instrument. The spinal BMD measurements with the 2 techniques were linearly related and highly correlated (r = 0.98) over a range from severely osteopenic to high normal. This correlation was not affected by the age, weight, or BMD of the patient measured. Quantitative digital radiography's long-term reproducibility using the spine phantom was stable for 180 days (coefficient of variation, 0.23%); DPA values were 3 times as variable for 170 days (coefficient of variation 0.73%) and increased 1.0% (P less than 0.0001) after a software change. The short term reproducibility of quantitative digital radiography, estimated from paired patient measurements, was 2-fold better than reported values for DPA and was independent of the patient's age, weight, or BMD. Measurement time by quantitative digital radiography was 5-8 min, with a maximum radiation exposure of 3 mrem, significantly lower than the corresponding DPA values. Quantitative digital radiography's image resolution was superior to that of DPA, enabling it to measure more bones. These advantages along with the elimination of 153Gd source changes and Nuclear Regulatory Commission licensing requirements indicate that quantitative digital radiography is the superior method for spinal BMD measurements.

Adult↗
PubMed2002

Mycobacterium avium complex lung disease in immunocompetent patients: radiography-CT correlation.

This study aimed to describe and correlate the chest radiography and CT findings of Mycobacterium avium complex (MAC) lung disease in immunocompetent patients. 26 patients fulfilled The American Thoracic Society criteria for MAC lung disease and underwent chest radiography and CT within 6 weeks of positive cultures. All abnormalities and predominant lobar involvement were recorded and abnormalities on chest radiography were correlated with those on CT. The images were evaluated by two chest radiologists and decisions were reached by consensus. 21 females and 5 males, with an overall mean age of 69 years, were included in the study. All chest radiographs and CT scans were abnormal. On chest radiography, overinflation was demonstrated in 18 patients. CT scan abnormalities included atelectasis (n=17), bronchiectasis (n=24), cavities (n=13), consolidation (n=3), emphysema (n=11), ground-glass opacity (n=8), linear opacities (n=26), mediastinal lymphadenopathy (n=3), nodules (n=25) and pleural disease (n=15). CT findings were at variance with chest radiography findings in 15 lobes. A new feature from this study is that the majority of patients with MAC lung disease demonstrate overinflation on chest radiography. 19% of cases had predominant upper lobe disease, indistinguishable from post-primary Mycobacterium tuberculosis infection. 77% of cases demonstrated the major imaging criteria of MAC lung disease. These are ill defined nodules, bronchiectasis, predominant middle lobe and/or lingular abnormalities, with or without overinflation. We believe that these characteristic radiological signs will assist the physician in the diagnostic work-up of patients with MAC lung disease.

Aged↗
PubMed1998

Predictive value of specimen radiography for core needle biopsy of noncalcified breast masses.

OBJECTIVE: Our objective was to determine the predictive value of specimen radiography for large core (14-gauge) needle biopsy of noncalcified breast masses. SUBJECTS AND METHODS: Eighty-four biopsies of 83 breast masses yielded 403 specimens. Specimens showing dense material on specimen radiography were predicted to be diagnostic; specimens showing intermediate- or low-density material were predicted to be nondiagnostic. Specimen radiographic and histopathologic findings were correlated for each specimen using vital dyes to mark individual specimens. RESULTS: Of the 403 specimens, 307 (76%) contained diagnostic material representative of the lesion, with a specific diagnosis achieved for 82 (99%) of 83 lesions (62 benign, 20 malignant). Of the 293 passes containing dense material, 268 (91%) proved to be diagnostic; 11 (18%) of 62 specimens containing only low-density material proved to be diagnostic. Of the 25 (9%) of 293 specimens containing radiographically dense but nondiagnostic material, 18 (72%) showed focal fibrosis and had missed the lesion; 15 (83%) of 18 such specimens were obtained in dense parenchyma. The positive predictive value of specimen radiography was 13 (100%) of 13 in fatty breasts; 77 (96%) of 80 in breasts with minimal scattered fibroglandular elements; 91 (94%) of 97 in heterogeneously dense breasts; and 35 (70%) of 50 in breasts with extremely dense parenchyma. Of the 16 lesions sampled stereotactically, specimen radiography helped assess the inadequacy of initial sampling in three (19%). In six (9%) of 68 sonographically guided biopsies, only one or two specimens could be obtained; specimen radiography helped us predict whether material was adequate for diagnosis. CONCLUSION: Radiography of core specimens obtained from noncalcified breast masses accurately reveals the adequacy of sampling unless the breast parenchyma is extremely dense. Such immediate assessment can help ensure adequate material from lesions that are difficult to biopsy and can thereby improve the diagnostic yield of large core needle breast biopsy.

Adolescent↗
PubMed2002

Multidetector CT of the spine in multiple myeloma: comparison with MR imaging and radiography.

OBJECTIVE: The purpose of this study was to compare multidetector CT (MDCT) of the thoracic and lumbar segments of the spine with MR imaging and conventional radiography for bone lesion detection and for evaluating the risk of vertebral fracture in multiple myeloma. SUBJECTS AND METHODS: Eighteen patients with multiple myeloma stage III (according to the criteria of Durie and Salmon) underwent MDCT, conventional radiography, and MR imaging of the lumbar and thoracic spine. MDCT was performed using a standard protocol with no contrast material. Source images were reconstructed using an effective slice thickness of 3 mm with an overlapping reconstruction increment (0.8 mm). Secondary coronal and sagittal multiplanar reformations were exclusively used for establishing the diagnosis. Findings were compared with those of MR imaging and conventional radiography. RESULTS: In all patients, coronal and sagittal multiplanar reformations depicted the extent of osseous destruction and provided detailed information about osseous infiltration and potential bone instability. Compared with conventional radiography, an additional 24 affected vertebrae, 15 additional vertebral fractures, and six vertebrae at further risk of fracture were detected on MDCT. Compared with MR imaging, three additional endangered vertebrae were detected on MDCT. MR imaging alone would have lead to an understaging of five (27.8%) of 18 patients. Using combined radiography and MR imaging, disease in three (16.7%) of 18 patients would have been understaged. CONCLUSION: MDCT seems to be preferable to conventional radiography in evaluating bone destruction in multiple myeloma. In combination with MR imaging, detailed information for staging these tumors is obtained. For the initial staging in patients with multiple myeloma, MDCT in combination with MR imaging seems to be the method of choice.

Aged↗
PubMed2002

[Lateral radiography of the knee with single-leg standing].

The purpose of this investigation was to accomplish reproducible radiography of single-leg standing lateral radiography of the knee by adjusting lateral rotation using a ruler to measure foot position. After preliminary assessment of three-dimensional CT of the knees of normal volunteers, the best adjustment of external rotation was estimated. A ruler was made for use in adjusting the angle of knee rotation by measuring foot rotation. Based on the foot rotation measured by this ruler, the positioning of radiography was adjusted to correct rotation. Rotation was estimated by the distance between the posterior edges of the lateral and medial femoral condyles. Fifteen-degree and 17.5-degree rotations were used for correction. Correction of rotation was 17 degrees on average. This helped not only to correct external rotation in the initial radiography but also to correct rotation for repeat radiography. Our method is quantitative and highly reproducible, and it increases the success rate of lateral knee radiography.

Adolescent↗
PubMed2003

[Sinus radiography and low-dose CT in the diagnosis of acute sinusitis. ].

Background. Although CT is considered the method of choice in the evaluation of inflammatory sinus disease, plain film radiography is still used, as repetitive CT examinations may impart a considerable radiation dose to the lens. We designed a new low-dose CT examination and compared this and plain film radiography to standard-dose CT. Methods and materials. The new CT low-dose protocol consisted of ten coronal scans at 40 mAs and 1 mm collimation. 47 patients referred for acute sinusitis were examined with plain film radiography, low-dose and standard-dose CT on the same day. The latter was used as "the gold standard". Results. The sensitivity of plain film radiography was low (< 50 %) except for the maxillary sinus (80 %). The overall sensitivity of low-dose CT was 95 % and the specificity 97 %. Effective dose and lens dose of low-dose CT were 3 % and 2 % respectively compared to standard-dose CT. Corresponding values for conventional radiography were 13 % and 2 %. Interpretation. Low-dose CT had image quality comparable to standard-dose CT and a dose to the eye lens equal to plain film radiography. Low-dose CT should be the method of choice in patients referred for acute sinusitis.

Acute Disease↗
PubMed2003

Optimization of analysis of skeletal ossification of laboratory animals by means of digital radiography software options.

Digital radiography software enables image manipulation and reformatting, thus allowing precise diagnosis and measurements even in cases when exposure parameters are suboptimum and visualized structures are faintly radiopaque. The aim of the paper is evaluation of digital radiography software options in optimization of analysis of skeletal ossification in rats. Wistar at pups at the age 0 to 22 days of postnatal life were radiographed by means of a storage phosphor digital radiography system. In order to optimize viewing conditions as well as density nd linear measurements all available image reformatting options and filters of digital radiography software Digora 2.0 were used and evaluated. Application of digital radiography image enhancement options was found advantageous in optimization and improvement of viewing conditions and it allowed higher accuracy and reproducibility of the measurements. Digital radiography is a novel and precise tool in determination of skeleton ossification and could be used as a supplement to routine staining methods.

Animals↗