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At least 307 records · Page 17Linked to original sources
PubMed1977

Diarrhea, red diapers, and child abuse: clinical alertness needed for recognition; clinical skill needed for success in management.

Three children were chronically given phenolphthalein in the form of laxatives by emotionally disturbed mothers. All children had repeated hospitalizations and extensive diagnostic testing because of recurrent intractable unexplained diarrhea. One child died. Pink-red urine and stool were passed at some time during their illnesses. The presence of phenolphthalein was tested for by application of dilute acid of dilute alkali to the diapers causing respectively disappearance of deepening of the pink-red color. Cases went undiagnosed for prolonged intervals because mothers seemed exemplary. Evidence of their psychiatric illnesses was found once the possibility was considered. Phenolphthalein poisoning should be tested for in any case of intractable diarrhea when objective evidence of intestinal mucosal damage cannot be found. The condition represents a heretofore unrecognized variant of child abuse of battering.

Cathartics↗
PubMed1989

Examining the needs of youth in secure custody: why we need to "recreate the wheel" in Canadian juvenile justice.

The current study reviews the personal characteristics of 32 consecutive admissions to a secure custody centre in one southwest Ontario jurisdiction under the Young Offenders Act. Results indicated that there was considerable variability amongst the group regarding court history and the seriousness of the charge on which committal was made. Background history data suggested that the problems of youths committed to secure custody reflect considerable difficulties within families and school. The discussion questions whether the youths in this group are better served through the dispositions emphasizing custody-deterrence or rehabilitation-treatment. Implications for young offender policy are also presented.

Adolescent↗
PubMed2002

Gills are needed for ionoregulation before they are needed for O(2) uptake in developing zebrafish, Danio rerio.

A variation on the classic ablation method was used to determine whether O(2) uptake or ionoregulation is the first to shift from the skin to the gills in developing zebrafish, Danio rerio. Zebrafish larvae, ranging in age from 3 to 21 days postfertilization, were prevented from ventilating their gills and forced to rely on cutaneous processes by exposing them to one of two anaesthetics (tricaine methanesulphonate or phenoxyethanol) or by embedding their gills in agar. They were then placed in solutions designed to compensate selectively for impaired O(2) uptake (42% O(2)), impaired ionoregulatory capacity (50% physiological saline) or impairment of both functions (42% O(2)+50% physiological saline). Survival under these conditions was compared with that in normoxic (21% O(2)) fresh water. Neither hyperoxia nor 50% physiological saline had any significant effect on the survival of newly hatched larvae (3 days postfertilization), suggesting that at this stage cutaneous exchange was sufficient to satisfy both ionoregulatory and respiratory requirements. At 7 days postfertilization, the skin still appeared capable of satisfying the O(2) requirements of larvae but not their ionoregulatory requirements. Physiological saline significantly improved survival at 7 days postfertilization; hyperoxia did not. At 14 days postfertilization, both hyperoxia and 50% saline significantly improved survival, indicating that at this stage gills were required for O(2) uptake as well as for ionoregulation. At 21 days postfertilization, only hyperoxia significantly improved survival. By this stage, larvae apparently are so dependent on gills for O(2) uptake that they suffocate before the effects of ionoregulatory impairment become apparent. Thus, it would appear that in zebrafish it is the ionoregulatory capacity of the skin not its ability to take up O(2) that first becomes limiting. This raises the possibility that ionoregulatory pressures may play a more important role in gill development than is generally appreciated.

Animals↗