Total hip replacement using the Charnley prosthesis in inflammatory joint disease.
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Arthritis, Juvenile↗
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[Silicon prosthesis of finger joints].
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Finger Joint↗
[Total hip prosthesis using artificial joint cartilage].
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Adult↗
Osteomyelitis: clinical update for practical guidelines.
Bone infections represent a diagnostic or therapeutic challenge for the infectivologist, orthopaedic surgeon, radiologist and nuclear medicine physician. Staphylococcus aureus is the major bacterium responsible for bone infections although Mycobacterium tuberculosis is emerging as an infectious agent in Italy because of immigration from Africa and Asia. Osteomyelitis requires long and expensive antibiotic treatment, including rifampicin administered parenterally for several weeks and the use of antimicrobial-impregnated cement in prosthesis substitution. Sometimes it is necessary to carry out surgical debridement of a necrotic bone or the consolidation of compromised bones and joint prosthesis implants. Radiographs and bone cultures are mainstays for the diagnosis of bone infections but are often useless in the lengthy management of these patients. Diagnosis of skeletal infections still includes conventional radiography but magnetic resonance imaging is essential in haematogenous and spinal infections. Bone scans are still useful in acute osteomyelitis whereas scintigraphy using labelled white blood cells is preferred in infections of peripheral bone segments or joint prosthesis. In the axial skeleton a combination of an agent for detecting inflammation ((67)Ga citrate) and a metabolic agent ((99m)Tc-methylene diphosphonate) enables an infection and an area of increased metabolic activity to be distinguished. [(18)F]Fluorodeoxyglucose positron emission tomography, where available, has a significant impact in the study of infections using radionuclides: high-resolution tomographic images represent an effective alternative to gallium in the assessment of inflammation of spine lesions but a comparison with morphological examinations (computed tomography or magnetic resonance imaging) is essential.
Humans↗
FEA analysis of silicone MCP implant.
This paper discusses finite element study of silicone rubber prosthesis for the metacarpophalangeal joint of the hand. Based on the experimental data, a material model which incorporates test data available for different stress states was chosen and calibrated. Finite element models for three commercially available silicone joint prosthesis were developed. All models incorporated the same material model and allowed for large deformations. These models were validated against the experimental data and analyzed under demanding loading conditions. Results such as highly non-linear material behavior, dependence on the loading history and large deformations near wrinkle formation in the hinge area of the joint clearly show the necessity and importance of using multi-stress- state non-linear material models and accounting for large deformations.
Computer Simulation↗
[Two-stage reimplantation using spacers--the method of choice in treatment of hip joint prosthesis-related infections. Comparison with methods used from 1979 to 1998].
PURPOSE OF THE STUDY: Several therapies are available for the treatment of deep infection in total hip arthroplasty but none is completely successful; there is no consensus on an optimal method. The aim of this study was to evaluate the treatment used in our institution and its outcomes over the last 20 years. In each method, the success of treatment was evaluated in terms of both infection control and restoration of function in the treated joint. MATERIAL: A total of 172 patients with infected total hip replacements were treated at the First Orthopedic Clinic of the First Faculty of Medicine, Charles University, Prague, between 1979 and 1998. Our sample consisted of 132 patients, 92 men and 40 women. Resection arthroplasty was performed in 62 patients. Two-stage reimplantation was used in 64 patients. Two-stage reimplantation involving skeletal traction was applied in 35 and a block spacer was used in 29 patients. The remaining patients were treated by other techniques. METHODS: The type of infection was classified according to the Coventry system. The outcome of surgery was assessed on the basis of the Tsukayma rating system, radiographic findings and the Harris hip score. RESULTS: The average follow-up time from the definitive operation was 70.8 months. In the patients who had resection arthroplasty only, the cure rate of infection was 91.9%. However, an increase in the Harris hip score, as compared with the condition before surgery, was low (9.7 points). In the patients treated by the two-stage reimplantation without a spacer but with skeletal traction, the cure rate of infection was 94.3% and the Harris score increased by 20 points. The patients who were treated by two-stage reimplantation with a spacer showed an infection cure rate of 96.5% and an increase in the Harris score by 29 points. This increase was higher by 9 points in comparison with the patients who had reimplantation without the use of a spacer. An even greater difference (28.2 points) was found when the outcomes of this technique were compared with those of resection arthroplasty. The incidence of spacer dislocation in 21% of the cases was an unexpected finding. DISCUSSION: No great differences in outcome in terms of infection cure rate were found among the methods used, i.e., two-stage reimplantation facilitated a better function for the hip joint than Girdlestone's operation. The use of a spacer in two-stage reimplantation ensured a greater comfort for the patient during treatment and gave better results in terms of joint function than treatment without a spacer. The use of a cemented spacer is an optimal method that not only ensures the stability of a limb during the period necessary for infection control but also provides conditions for the prospective implantation of a new prosthesis. The spacer also permits delivery of high-dose local antibiotics released from the cement as well as makes space for a long-term application of antibiotic-containing lavage. CONCLUSIONS: The rate of success in the treatment of an infected hip arthroplasty and the possibility of preserving the implant and thus enabling the patient to move comfortably are currently high. The prerequisite is early diagnosis and a radical surgical approach that involves the use of a method leading to the most effective eradication of infection and the maintenance of a good function for the joint. The reimplantation of a new prosthesis, after removal of the previous one and debridement of all infected tissue and material, combined with a targeted antibiotic therapy, is the method of choice for both the patient and the surgeon.
Adult↗
Preliminary results of a survey of the use of antimicrobial agents as prophylaxis in orthopedic surgery.
An epidemiological survey of the use of antimicrobial prophylaxis in Italian hospitals was carried out under the auspices of the Journal of Chemotherapy. Out of 500 Italian orthopedic centers queried, 225 agreed to participate in this study. A total of 136,321 surgical procedures were reported in the 166 centers reporting complete answers on type of surgery. They comprised hip and knee prosthesis (13.9%), spine surgery (4%), hip endoprosthesis (5.2%), osteosynthesis (26.9%), arthroscopy (24.4%), and others (25.5%). Perioperative antimicrobial prophylaxis was used in 75% of operations (ranging from 57.1% to 99.4% in arthroscopy and joint prosthesis, respectively). Short term (<24 h) antimicrobial prophylaxis was performed in 38.4% of the 206 centers answering this question correctly. 61.1% of centers employed single agent prophylaxis and 70.8% of these prescriptions were betalactam antibiotics. Bacteriological analysis revealed gram-positive isolates in 73.3% of cases. Methicillin resistance was present in 45% of 915 tested strains. Out of 4221 patients with high risk of infectious complications (joint prosthesis surgery) given antimicrobial prophylaxis in 46 centers, the percentage of surgical wound infections was overall 2.1%, while that of non-surgical wound infections was 3.6%. The total infection rate was decreased by about half in association with long-term (>24 h) as compared to short-term (<24 h) antibiotic treatment (3.7% vs 7.6%, respectively), and with use of antibiotic drug combinations vs single antibiotic drugs (3.9 vs 6.6%, respectively). The incidence of surgical-site infection was not decreased by extending the chemoprophylaxis for more than the first 24 h after surgery, while it was reduced from 2.5 to 1.4% by use of combination antibiotic therapy.
Aged↗
[Antibiotic prophylaxis of postoperative infection in orthopedics. Results of an epidemiologic survey in Italy conducted by the Journal of Chemotherapy].
An epidemiological survey of the use of antimicrobial prophylaxis in Italian hospitals was carried out under the auspices of the Journal of Chemotherapy. Out of 500 Italian orthopedic centers requested, 225 have participated in this study. A total of 136,321 surgical procedures were reported in the 166 centers reporting complete answers on type of surgery. They comprised hip and knee prosthesis (13.9%), spine surgery (4%), hip endoprosthesis (5.2%), osteosynthesis (26.9%), arthroscopy (24.4%), and others (25.5%). Perioperative antimicrobial prophylaxis was used in 75% of operations (ranging from 57.1% to 99.4% in arthroscopy and joint prosthesis, respectively). Short term (< 24 h) antimicrobial prophylaxis was performed in 38.4% of the 206 Centers answering this question correctly. 61.1% of Centers employed single agent prophylaxis. 70.8% of these prescriptions were betalactam antibiotics. Bacteriological analysis of the wound in 86 Centers (total number of isolates 2013) revealed the presence of Gram-positive isolates in 73.7% of cases. Methicillin resistance was expressed in 45% of 915 tested strains. Out of 4221 patients with high risk of infectious complications (joint prosthesis surgery) given antimicrobial prophylaxis in 46 Centers, the percentage of surgical wound infections was overall 2.1%, while that of non-surgical wound infections was 3.6%. A decrease in the total infection rate by about half was associated with long-term (> 24 h) as compared to short-term (< 24 h) antibiotic treatment (3.7 vs 7.6%, respectively), and with the use of antibiotic drug combinations vs single antibiotic drugs (3.9 vs 6.6%, respectively). The incidence of surgical-site infection is not decreased by extending the chemoprophylaxis for more than the first 24 h after surgery, while it is reduced from 2.5 to 1.4% by use of combination antibiotic therapy.
Antibiotic Prophylaxis↗
Relationship between body mass index and activity in hip or knee arthroplasty patients.
The weight of patients has not been demonstrated to have a consistent effect on the rate of polyethylene wear in clinical studies of total joint replacement. For this reason, we analyzed the relationship between quantitative activity, measured with a pedometer, and body mass index, a measure of obesity. Data were acquired for 209 individuals, 22-82 years of age; all were independent community walkers. One hundred and fifty-one had a well functioning total hip or knee replacement. Analysis of variance was used to evaluate the relationship between activity and body mass index, with adjustments for confounding variables. The 58 individuals with no total joint prosthesis averaged 7,781 steps per day, which was higher (p < 0.01) than those with a total hip (5,869 steps per day) or knee (4,597 steps per day) replacement. The subjects with no total joint prosthesis were, however, younger than the patients with a prosthesis (p < 0.01), and the body mass index of the patients with a total knee replacement was higher than that of the patients with a hip replacement and that of the subjects with no prosthesis (p < 0.01). After adjustment for differences in age, gender, and Charnley class, a higher body mass index (greater obesity) was associated with lower activity (p = 0.05). With regard to the rate of polyethylene wear, decreased ambulatory activity may counterbalance increased weight, which could, at least in part, explain why weight has not had a consistent effect on polyethylene wear in clinical studies. Wear is a function of use, not time. The effect of obesity on activity should be considered in radiographic studies of wear and other outcome assessments of total joint replacements.
Adult↗
[A contribution to the differential indication of endoprosthetic knee-joint substitution (author's transl)].
The article describes a few guiding points for indicating the need for a knee-joint endoprosthesis, basing on experience with 253 cases, followed up for 2--48 months. Following the application of prostheses according to Walldius-Debeyre and Guepar, several complications were seen which we tried to reduce by introducing four prostheses of different sizes, since the choice of the implantates could be adapted to the prevailing anatomical conditions. A hinged-joint prosthesis of the St. George type is indicated in cases of most severe axial deviation, severe flexion contraction, extensive loss of bone substance, and instability of the ligaments. Sheeban's prosthesis is indicated in severe damage involving both compartments, limited frontal axial deviation, and flexion contraction of not more than 25 degrees with intact lateral ligaments. In younger patients with rheumatoid arthritis we implant the Geomedic prosthesis. If only one knee-joint compartment is involved, and after the possibility of readjustment osteotomy has been excluded, we consider a sliding prosthesis to be the prosthesis of choice.
Age Factors↗
Risk factors for septic arthritis in patients with joint disease. A prospective study.
OBJECTIVE: To quantify potential risk factors for septic arthritis, in order to identify a basis for prevention. METHODS: The occurrence of potential risk factors for septic arthritis in patients with joint diseases attending a rheumatic disease clinic was prospectively monitored at 3-month intervals over a period of 3 years. Potential risk factors investigated were type of joint disease, comorbidity, medication, joint prosthesis, infections, and invasive procedures. The frequencies of risk factors in patients with and those without septic arthritis were compared using multiple logistic regression analysis. RESULTS: There were 37 patients with and 4,870 without septic arthritis. Risk factors for developing septic arthritis were age > or = 80 years (odds ratio [OR] = 3.5, 95% confidence interval [95% CI] 1.4-8.6), diabetes mellitus (OR = 3.3, 95% CI 1.1-10.1), rheumatoid arthritis (OR = 4.0, 95% CI 1.9-8.3), hip and/or knee prosthesis (OR = 15, 95% CI 4.1-54.3), joint surgery (OR = 5.1, 95% CI 2.2-11.9), and skin infection (OR = 27.2, 95% CI 7.6-97.1). CONCLUSION: These findings indicate that preventive measures against septic arthritis in patients with joint diseases should mainly be directed at those with joint prostheses and/or skin infection.
Age Factors↗
[Long-term results of proximal interphalangeal resection-arthroplasty using the Swanson silastic implant].
238 PIP joint arthroplasties with "Silastic" implant were performed between 1969 and 1990. Their results were evaluated after 12 to 24 months. We reviewed 25 patients operated between 1971 and 1988 with a follow-up of 4 to 23 years. The results are evaluated in terms of joint mobility, pain, stability, strength, radiological appearance and patient satisfaction. These results are identical to those observed at short follow-up indicating the absence of any significant deterioration. The result obtained at 12 months postoperatively will therefore be maintained at 12 years. Our conclusion is that unless an ideal arthroplasty with joint prosthesis can be shown to be effective, joint resection-arthroplasty remains a valuable and durable solution for the treatment of PIP joint stiffness.
Adolescent↗
Implants designed for finger joints. A roentgenorgraphic study and a study of implant wear and tear.
Two types of flexible finger implants (one intramedullary movable, the Silastic Finger Joint Implant, Swanson design, and the other presumable intramedullary fixed, the Niebauer T-M Cutter Metacarpophalangeal Joint Prosthesis) were subjected to animal trials. Forty-four Swanson implants and 33 Niebauer implants were implanted in the knee joint of rabbits. Roentgenographic examinations were carried out immediately after surgery and then at monthly intervals. The joint was examined in the lateral projection in a flexed and in an extended position to obtain better information about the behaviour of the implant. The Swanson implant was assessed as being intramedullary movable. The Niebauer implant was found to bend within other parts than just the thin central part of the midsection as it is supposed to do. Intramedullary bone formation was seen along the distal stem of the Swanson implant. It developed in a very typical manner considered to be related to the motion of the stem. A similar phenomenon was seen along the distal stem of some of the Niebauer implants and was considered a sign of insufficient fixation of the stem. Cortical erosion and periosteal callus formation were found in the femur at the site at which the proximal stem of the Swanson implant was in direct contact with the bone. The implants were examined at autopsy both in situ and after removal. The Swanson implants showed consistently a wearing of the surface and a permanent deformation. Isolated cracks were seen in 8/44 implants, while fractures, either isolated or in combination with cracks and/or fragmentation, were seen in 22/44 implants. It was not possible to evaluate deformation of the Niebauer implants. Slight wearing was seen in 4/32 implants. Cracks, fragmentations and fractures were seen either isolated (except for the fragmentations) or in different combinations with no specific pattern in 25/32 implants. The combination of inelastic dacron fibres and elastic silicone rubber in one functional unit as in the Niebauer implant was considered the main cause of the damage.
Animals↗
Infectious disease consultations and antibiotic usage in a Turkish university hospital.
OBJECTIVES: The aim of this study was to investigate the various features of infectious disease (ID) consultations and the usage of antibiotics in a Turkish university hospital. METHODS: A total of 395 consultation requests were recorded during a three-year period. RESULTS: The departments most frequently requesting the consultation services of the ID department were Orthopedics (29.6%), Neurology (18.5%), Cardiology (11.8%) and Internal Medicine (10.4%). The main reasons were for diagnosis of unexplained fever (42.3%) and for antibiotic modification according to culture results (18%). Diagnoses made by the ID consultant were pneumonia (16.7%), urinary tract infections (9.3%), bone and joint prosthesis infections (9.1%) and in 15.7% of the investigated patients, no infectious focus was determined. It was recognized that the use of antibiotics had already been initiated in the great majority of patients (67.1%) before the consultation request. While the current therapy was changed in 57.4% of these patients, antibiotics were not necessary for 9.8%. CONCLUSIONS: Since the most common diagnoses were respiratory and urinary tract or bone and joint prosthesis infections, the ID specialists should have detailed knowledge of these problems. Usage of antibiotics without ID consultation was prevalent, therefore a continuous educational program is a necessity for healthcare workers in the hospital.
Anti-Bacterial Agents↗
Prosthesis position in shoulder arthroplasty. A cadaver study of the humeral component.
In six cadaver shoulder joints, the external rotation was measured applying a constant external torque to the humerus before and after insertion of a non-constrained shoulder joint prosthesis at different degrees of retroversion. At 35-45 degrees of retroversion there was no difference between the external rotation of the inserted prosthesis and the external rotation of the joint before arthroplasty.
Biomechanical Phenomena↗
[Basis-free frontal section in joint bridge prosthesis].
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Aged↗
Total replacement of the knee joint by prosthesis. I.
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Animals↗
Freiberg's infraction of the second metatarsal head with formation of multiple loose bodies.
Freiberg's infraction is an osteonecrotic disease process that most often involves the head of the second metatarsal. Establishing a diagnosis can be difficult early in the disease course, mimicking such pathologic processes as stress fracture, septic joint infection, tumors, metatarsalgia, various arthritic diseases, etc. A review of the literature reveals many treatment options and many theories of its etiology. The clinical signs and symptoms, review of the etiologies, radiographic presentation, and conservative and surgical treatments of this disease are presented. A case history and treatment summary of a patient afflicted with Freiberg's infarction involving the second metatarsophalangeal joint of the right foot is presented. Treatment consisted of evacuation of multiple loose bodies from the joint, resection arthroplasty of the diseased joint, and insertion of a total joint prosthesis.
Adult↗