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At least 307 records · Page 17Linked to original sources
PubMed1997

General outbreaks of infectious intestinal disease associated with milk and dairy products in England and Wales: 1992 to 1996.

Twenty general outbreaks of food poisoning in England and Wales associated with the consumption of milk and dairy products were reported to the PHLS Communicable Disease Surveillance Centre between 1992 and 1996. A total of 600 people were ill and at least 45 people were admitted to hospital but no deaths were reported. Salmonella species were responsible for 11 outbreaks, Campylobacter species for five, Vero cytotoxin producing Escherichia coli O157 (VTEC) for three, and Cryptosporidium parvum for one. Outbreaks were associated with hotels (2 outbreaks), a psychogeriatric hospital, schools (3), a Royal Air Force base, a farm visit, an outdoor festival (2), and community outbreaks associated with milk supplied direct from farms (8). Milk was implicated in 16 outbreaks; 10 of which were associated with unpasteurised milk. Two outbreaks were associated with eating contaminated ice cream, and two with eating contaminated cheese. All these outbreaks could have been prevented by pasteurisation and simple hygienic measures.

Adult↗
PubMedDate not supplied

[Immunoproliferative small intestinal disease. Report of a case with immunohistochemical and ultrastructural study].

The clinico-pathological characteristics of a 22 years old mestizo mexican patient with immunoproliferative small intestinal disease (IPSID) are described. The patient coursed with chronic diarrhea, malabsorption, and a 30 kg weight loss. The laboratory tests revealed hypokalemia, hypocalcemia, hypoalbuminemia and decreased levels of immunoglobulins. The histological changes in the endoscopic biopsies included a dense lymphoplasmacytic infiltrate in the lamina propria that produced vellosity blunting and distortion of the crypts. The immunohistochemical analysis disclosed that almost every cell was positive to heavy chains and negative to light chains. The radiological studies showed thickening of the intestinal folds and mesenteric adenomegalies. In the full thickness biopsy of the yeyunum, in addition to the lymphoplasmacytic infiltrate, a high grade malignant lymphoma infiltrating the regional lymph nodes was documented. An ultrastructural study revealed viruses that resembled the morphology described for the Epstein-Barr virus. The main clinico-pathological findings of other eight mexican patients with IPSID previously reported are commented. It is concluded that the IPSID is a rare disease in our country but it can be found sporadically.

Adult↗
PubMed2001

Characterisation of strains of enteroaggregative Escherichia coli isolated during the infectious intestinal disease study in England.

Strains of Escherichia coli, hybridising with a DNA probe for enteroaggregative E. coli (EAggEC), were isolated from patients with infectious intestinal disease (IID) or gastro-enteritis, and healthy controls during the study of IID in England. Of 3506 cases presenting with an IID, 160 (4.6%) had faecal EAggEC as compared with 46 (1.7%) of 2772 healthy controls, 53% of EAggEC isolated from each of the 'case' and the 'control' groups adhered in a 'stacked-brick' formation. Strains from cases and controls belonged to over 39 and 14 different serogroups respectively, and approximately half of the strains isolated did not react with antisera in the current somatic antigen serotyping scheme. Forty-nine cases with EAggEC (31%) had a known history of foreign travel. Over 50% of strains isolated from cases and controls were resistant to one or more of eight antimicrobials, and antimicrobial resistance was not statistically significantly more common among cases with a known history of foreign travel (p = 0.57). These data form part of the largest investigation carried out on these organisms in the UK to date and provide the most comprehensive analysis of strains of EAggEC isolated from the general population of England.

Case-Control Studies↗
PubMed1978

[Properties of E. coli of serological group 06:K13(L) isolated in acute intestinal diseases].

A study of 88 E. coli strains belonging to serological group 06: K13 (L) isolated from 50 children and 5 adults suffering from acute intestinal disturbances permitted to refer them to the serological types 06: K13 (L):H1 (82 strains) and 06: K13 (L): H--(6 strains), and to 5 biochemical types. Repeated isolation of E. coli belonging to serlogical group 06: K13 (L) in patients with acute intestinal diseases, and their absence in healthy children and adults indicated these microbes to be a possible etiological factor of the disease and to refer to the group group of enteropathogenic ones. Wide introduction of agglutinating sera 06: K13(L) into the work of practical laboratories is of expedience in connection with this.

Acute Disease↗
PubMed1991

[Epidemiologic analysis of the report "Non-specific intestinal diseases" (Slovakia 1975-1989)].

The authors submit an analysis of the notified morbidity, the number of deaths and work incapacity on account of "non-specified intestinal diseases" ("009") in Slovakia in 1975-1989. They focus attention on the age distribution and seasonal incidence of these diseases. During the investigation period 27,075 cases were reported and the morbidity has a rising trend. The most severely affected age group are infants where the death rate is highest. The authors found a marked disproportion between the number of notified diseases and the work incapacity on account of "009", which accounts for 2/3 of all work incapacities on account of intestinal infections.

Adolescent↗
PubMed1995

Intestinal permeability testing in dogs with diet-responsive intestinal disease.

Fifteen dogs with signs of small and, or, large bowel disease that responded clinically to an exclusion diet were studied, using differential sugar absorption as an objective parameter of the mucosal response to the diet. Intestinal permeability and function were assessed by determining the urinary excretion ratios of lactulose/rhamnose and xylose/3-O-methylglucose, respectively, following oral administration of a mixture of these four sugars. Five dogs, all retrievers, were tentatively diagnosed as having dietary hypersensitivity, based upon resolution of clinical signs and normalisation of high intestinal permeability following an exclusion diet and recurrence of signs (in four of five dogs) upon challenge with the original diet. The fifth dog did not become symptomatic when challenged, but intestinal permeability increased. The remaining 10 dogs were diagnosed as having food intolerance, based upon clinical improvement on an exclusion diet, relapse on challenge with their original diet, but lack of improvement in intestinal permeability. These findings suggest that a differential sugar absorption test may be useful to determine the reasons for clinical response to exclusion diets. Demonstration of increased intestinal permeability with subsequent normalisation following an exclusion diet may be useful in the diagnosis of dietary hypersensitivity, while persistent abnormalities in intestinal permeability are suggestive of underlying intestinal disease and food intolerance.

Analysis of Variance↗
PubMed1980

[Psychosomatic aspects of expert judgement in gastro-intestinal disease (author's transl)].

Psychosomatic aspects in expert judgement about gastro-intestinal disease are important in regard to 3 particular problems: (1) establishing physical fitness for prison confinement, (2) establishing causal relationships between disease and military service, (3) judging the fitness for work, when annuities are demanded from the state insurance agencies. The point last mentioned is most important nowadays and is discussed therefore in more detail.

Disability Evaluation↗
PubMed1977

[Role of several conditionally-pathogenic enterobacteria in group acute intestinal diseases and food poisonings of unestablished etiology].

Results of studying group acute intestinal diseases of obscure (from the point of view of isolation of commonly known pathogenic bacteria of enteric family) etiology coursing by the type of food poisoning, in which conditioned pathogenic enterobacteria (Enterobacter cloacae, Klebsiella) demonstrated that the occurrence of these diseases was connected with ingestion of the same food product infected with the mentioned bacteria due to disturbance of the sanitary-epidemic regimen and rules of food storage. Carrier stage of conditioned pathogenic bacteria identical to those isolated from the patients was noted in contacts by the factor of infection transmission. Accumulation of factual material is necessary to solve the role played by conditioned pathogenic enterobacteria in such diseases.

Acute Disease↗
PubMed2005

Detection of viral, bacterial, and parasitological RNA or DNA of nine intestinal pathogens in fecal samples archived as part of the english infectious intestinal disease study: assessment of the stability of target nucleic acid.

Fecal samples were collected from cases and controls as part of the Infectious Intestinal Disease (IID) study in England and were stored as frozen suspensions for 8 to 12 years. The purpose of this study was to apply PCR-based procedures to assess the stability of pathogen-specific nucleic acid sequences present in this archive. Samples from which Cryptosporidium, Giardia, Salmonella, Campylobacter, enteroaggregative Escherichia coli (EAggEC), enterotoxigenic Clostridium perfringens, rotaviruses, noroviruses, or sapoviruses had been previously detected during the IID study using conventional methods were selected from the archive. A generic nucleic acid extraction method to recover RNA or DNA was used. Complementary DNA was generated from RNA by reverse transcription with random priming. Block-based and real-time PCR assays were used to amplify and detect gene fragments from each of these pathogens. The percentage reconfirmation of target was as follows: Giardia duodenalis 68%, Cryptosporidium 96%, Campylobacter 98%, Salmonella 98%, enterotoxigenic C perfringens 34%, EAggEC 93.3%, rotavirus 95%, norovirus 73%, and sapovirus 85%. This study has shown that nucleic acid can be extracted and specific sequences amplified and detected from archived fecal samples. The IID archive therefore represents a valuable resource for further studies, especially the investigation of the samples from which no pathogens had previously been detected.

Cryopreservation↗
PubMed1999

Ovarian endometriosis: a marker for more extensive pelvic and intestinal disease.

OBJECTIVE: To describe a computerized pelvic mapping system for pelvic and intestinal endometriosis and preliminary insights gained from it with respect to the effects of ovarian disease. DESIGN: Contemporaneous computerized tabulation of pelvic and intestinal sites of biopsy-proved endometriosis. SETTING: Tertiary referral center for the surgical treatment of endometriosis. PATIENT(S): One thousand nine hundred seventy-nine patients with endometriosis, 547 of whom had intestinal endometriosis. Patients with endometriosis with previous hysterectomy (n = 194) with or without castration were excluded from this total, leaving 1,785 patients for this study. INTERVENTION(S): Computer tabulation of sites of biopsy-proved pelvic and intestinal endometriosis. MAIN OUTCOME MEASURE(S): Extent of pelvic and intestinal endometriosis as reflected by number of pelvic or intestinal areas involved. Results were stratified by the presence or absence of ovarian endometriosis and by status of previous therapy. RESULT(S): Compared with patients without ovarian endometriosis, patients with ovarian endometriosis have more pelvic and intestinal areas involved by endometriosis. Patients with ovarian endometriosis and intestinal endometriosis are more likely to require full-thickness or segmental bowel resections for complete removal of intestinal disease. These findings persisted when adjusted for previous therapies or presence of superficial versus deep ovarian disease. Only 1.06% of patients had ovarian disease exclusively. CONCLUSION(S): Superficial or deep ovarian endometriosis is a marker for the presence of more extensive pelvic and intestinal disease. Surgeons diagnosing and treating only ovarian endometriosis may be underdiagnosing and undertreating their patients.

Biopsy↗
PubMed1983

[Enterotoxigenicity of opportunistic enterobacteria in acute intestinal diseases in children].

The enterotoxigenicity of 244 cultures of opportunistic enterobacteria isolated from 129 infants (up to 1 year old) with acute intestinal diseases and of 120 cultures of opportunistic enterobacteria isolated from 60 practically healthy children of the same age, having no record of intestinal disorders in their medical history, was studied. The study revealed that enterotoxigenic opportunistic enterobacteria were isolated from 68.99% of sick children, while from healthy children enterotoxigenic cultures were isolated in 3.33% of cases. Besides E. coli, enterotoxigenicity was also detected in other representatives of the family Enterobacteriaceae: C. freundii, Arizona, K. pneumoniae, H. alvei, Pr. vulgaris, Pr. morganii, Pr. rettgeri, Y. enterocolitica.

Acute Disease↗