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Results for “FASCIOLIASIS”

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At least 307 records · Page 17Linked to original sources
PubMed1993

[Prevalence of fascioliasis in humans, horses, pigs, and wild rabbits in 3 Chilean provinces].

This study sought to estimate for the first time the prevalence of fascioliasis among the rural population in the Chilean provinces of Curico, Talca, and Linares, while also determining the disease's prevalence among horses and wild rabbits in Curico and Talca and among pigs in Talca. From January 1986 to December 1990 a randomly selected sample of 5,861 persons in the three provinces was given intradermal, complement-fixation, double-diffusion, and immunoelectrophoresis tests to detect antibody to Fasciola hepatica. In addition, the ELISA test was used in Talca and Linares. Fecal specimens from horses and pigs were inspected for eggs, and the liver and bile ducts of rabbits were examined histopathologically. The overall prevalence of infection among the human subjects was 0.70%, with rates of 0.6% in Curico, 0.75% in Talca, and 0.71% in Linares. The prevalences of infection in horses, rabbits, and pigs were 13.5%, 6.1%, and 20.6%, respectively. It is estimated that some 2,000 people are infected in the study area. It is recommended that rabbits be taken into account in all control programs for this zoonosis.

Adolescent↗
PubMed1993

Studies on human fascioliasis in Egypt. 1--Seasonality of transmission.

The present study aimed at investigating the seasonality of human fascioliasis. The monthly distribution of acute infection was studied together with the monthly Lymnaea cailliaudi snail density and infection Infection was observed in both snail and human host through out the year. However maximal snail infection was observed during the months of June and July while the number of acute human infections peaked in August. It was concluded that summer was the highest transmission season. The clinical incubation period was considered one or two months.

Animals↗
PubMed1977

Partial purification of fasciola hepatica antigen for the immunodiagnosis of fascioliasis in rats.

When F. hepatica adult worm antigen is fractionated with Sephadex G-200, four major peaks are obtained. The first peak, when used as antigen in counterelectrophoresis, reacts with the serum of normal rats as well as from rats infected with F. hepatica for 5 weeks or longer. The crest and descending portion of peak II and the third peak are nonreactive with normal rat serum, but highly reactive with the serum of rats with F. hepatica. In addition, F. hepatica antigens cross-reacting with S. mansoni adult worm antisera are absent in these fractions. It is suggested, then, that these fractions of F. hepatica adult worm antigen be utilized for the immunodiagnosis of fascioliasis by CEP. Optimum antigen concentration for this test has been determined to be approximately 1.80 mg/ml protein.

Animals↗
PubMed1977

[Fascioliasis in sheep in South-western Jutland (author's transl)].

The frequency of fascioliasis in sheep of south-western Jutland has been determined on the basis of slaughterhouse registration of infected livers over a 5-year period (1969-1973). The average yearly percentage of adult sheep found to be infected ranged from 83.9 to 91.2%, whereas less than 1 % of the slaughtered lambs proved infected. The high infection percentage among adult animals and the strikingly low frequency among slaughter lambs could be explained by the characteristic management system of the marshland: In summer the sheep graze the dike and the foreland on its seaward side, and in winter the animals graze in the marshland. Lymnaea truncatula is not found on or at the seaward side of the dike, whereas it is abundant all over the marshland. Thus the lambs graze exclusively the snail-free area from which they are taken directly to the slaughterhouse. The summer grazing also protects the adult animals as they avoid the massive uptake of metacercariae which normally takes place in fluke infected areas in late summer.

Abattoirs↗
PubMed1997

Prevention of human fascioliasis: a study on the role of acids detergents and potassium permenganate in clearing salads from metacercariae.

Prevention of human fascioliasis could depend on clearing of the leafy salads from the metacercariae. The present work evaluated the role of some chemicals in detaching and killing this infective stage. It was observed that washing in running water for 10 minutes detached only 50% of the metacercariae. Citric acid in the concentration of (10 ml/L) commercial vinegar (120 ml/L), liquid soap (12 ml/L) and KMnO4 (24 mg/L) detached all metacercariae after 10 minutes exposure. The use of vinegar and KMnO4 is recommended: the first is lethal to other parasites in the vegetables, the second destroyed the metacercariae. Vegetable leaves were not softened and remained fresh.

Acetic Acid↗
PubMedDate not supplied

[Hepatic fascioliasis].

Hepatic fascioliasis is a pathology with an increasing incidence, morbidity and mortality all over the world and most particularly in our country, where endemic spots have been found, particularly in rural areas. Based on a clinical case which is supported by a revision of appropriate literature, the authors have made relevant considerations on bio-ecology, diagnosis, prognostic and treatment of this disease.

Antiplatyhelmintic Agents↗
PubMed1997

Detection of circulating antigens in blood to evaluate treatment of fascioliasis.

This work was designed to assess cure of human fascioliasis after triclabendazole treatment by detection of Fasciola antigen by a modified double antibody sandwich ELISA technique. The results showed that the test detected the antigen in the sera of all studied cases before treatment, while no antigen was detected after treatment. The results may suggest that antigen detection provides an accurate tool for diagnosis as well as the assessment of cure.

Animals↗
PubMed1997

SSU rDNA characterization of lymnaeid snails transmitting human fascioliasis in South and Central America.

The small subunit (18S) rRNA gene sequences of the lymnaeid morphs I and II (Mollusca: Gastropoda: Basommatophora: Lymnaeidae) transmitting human fascioliasis in the high endemic zone of the northern Bolivian Altiplano and of Lymnaea cubensis from Mexico and Guadeloupe island (Caribbean) have been obtained by direct polymerase chain reaction PCR cycle sequencing and silver staining methods and compared to that of the 6 most common European Lymnaeidae species. Results allow us to establish definitively the distinction between the lymnaeids from the northern Bolivian Altiplano and L. cubensis. Lymnaea cubensis is a valid species distributed in North and Central America but absent in the northern Bolivian Altiplano. Lymnaeid morphs I and II from the northern Bolivian Altiplano both present the same 18S rDNA sequence, which is moreover identical to that of the European species Lymnaea truncatula. Significant nucleotide substitutions in helix E10-1 of the variable region V2 of the secondary structure suggest the need for distinguishing L. cubensis in the subgenus Lymnaea (Bakerilymnaea) with L. (B.) cubensis as type species. The subgenus Lymnaea (Fossaria) is retained, with L. (F.) truncatula as type species. The larger number of nucleotides in the 18S rDNA sequence of L. cubensis (1,860 bp) with regard to the other Lymnaea species (1,843-1,852 bp) is tentatively related to the more ancient paleogeographic origin of L. cubensis. The grouping of L. cubensis with L. truncatula and the relationship of Lymnaea auricularia with Lymnaea peregra in the phylogenetic trees obtained show an evolutionary parallelism with the digenean parasite species they transmit, namely Fasciola hepatica and Fasciola gigantica, respectively.

Animals↗
PubMed1997

[Indirect ultra-micro-ELISA for detecting IgG antibodies in patients with fascioliasis].

The standardization of an ultramicroELISA for the detection of IgG antibodies anti excretory-secretory antigens of Fasciola hepatica (UME-Fasciola) is described. It was studied a considerable group of sera of which 56 were from patients with fascioliasis, 168 from patients with other parasitic diseases, and 300 from sound persons that were used as negative controls. As regards the parasitology test considered as "Gold Standard", the UME-Fasciola showed a sensitivity of 100%, an specificity of 98%, and predictive values for positives and negatives of 90.3% and 100%, respectively. Cross-reaction was only observed with the sera from patients infected with Opistorchis felineus. On comparing the UME-Fasciola with the conventional ELISA, it was obtained a concordance index of 95.5%.

Animals↗
PubMed1982

A Human Case Of Ectopic Fascioliasis In Korea.

A case of ectopic fascioliasis involving cecum and ascending colon was reported. This case was a 19-year old Korean female who had a history of postprandial aggravation of intermittent abdominal pain of 3 weeks duration. She was presented with an abdominal mass in the right upper quadrant, for which an operation(right hemicolectomy) was performed. Whole cecum and ascending colon showed multifocal tunnel-like necrotizing granulmas with central cavitations. Numerous Charcot-Leyden crystals were seen along tracts of the worm. The lesion was distributed throughout the entire thickness of the wall. Parasitological examination confirmed the worm found in the intestinal wall to be juvenile form of Fasciola species. Possibilities were discussed on the localization of the fluke and the mode of infection of present case.

Journal Article↗
PubMed1986

A human case of gallbladder fascioliasis in Korea.

The authors would record the fifth case of human fascioliasis in Korea, occurring in a 48 year old Korean man who lived in Munkyong, Kyongsangbuk-do. The diagnosis was based on the morphology and measurements of the eggs which were collected in necrotic debris from the tunnel-like ulcerations of the gallbladder wall which was surgically removed for a gall stone. Although we failed to find out the fluke in the specimen, there found an evidence of once presence of Fasciola in the inflamed wall of the gallbladder in this patient.

Journal Article↗