Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Destination”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 307 records · Page 17Linked to original sources
PubMed2005

Improving first-destination recruitment: nursing students' perceptions of three initiatives in London, England.

BACKGROUND: In the face of recruitment problems, managers are becoming increasingly proactive by introducing novel initiatives designed to encourage newly qualified nurses to apply to their institutions and catchment areas for employment. AIMS AND METHODS: Based on a multimethod survey of students from two British universities, this paper explores their perceptions of three very different initiatives, each at different stages of development and implementation. The 'Home Trust' initiative, provided the majority of clinical placements in one hospital. It was experienced by almost all the students who reported on it in questionnaires (n = 650), focus groups (n = 7) and interviews (n = 30). The 'On Secondment' initiative, seconded Health Care Assistants from their jobs into nurse education. It was experienced by a small number of students who reported on it in questionnaires (n = 32) and focus groups (n = 3). The 'Recruitment Clearing House' initiative planned to provide one interview for a range of hospitals and job vacancies in a large geographical catchment area. At the time of data collection, it was in a conceptual phase and was commented on in a small number of focus groups with students (n = 3). In addition, this initiative was commented on by recruitment managers in interviews (n = 3). RESULTS: Students held strong views on the positive and negative features of both current and prospective initiatives. Unique consumer insights were gained, particularly into their finer details and consequences. CONCLUSION: Student experiences and perceptions are valuable in the planning, implementation and review stages of local recruitment initiatives.

Attitude of Health Personnel↗
PubMed1997

Periplasmic Bar1 protease of Saccharomyces cerevisiae is active before reaching its extracellular destination.

Saccharomyces cerevisiae MATa and MAT alpha cells secrete a-factor and alpha-factor pheromones. These peptides act on cells of the opposite mating type. They induce physiological changes which allow the formation of diploid cells. MATa strains produce an extracellular protease which cleaves, and thus inactivates the MAT alpha cell-specific alpha-factor pheromone. This pepsin-like enzyme is encoded by the BAR1(SST1) gene and is secreted into the periplasmic space of MATa cells. We found that the Bar1p protease is already active in early compartments of the secretory pathway. Our results indicate that Bar1 protease tolerates large N-terminal extensions of its substrate and does not require Golgi-specific modifications such as outer-chain glycosylation for activity.

Amino Acid Sequence↗
PubMed2005

Effects of a shared protocol between urologists and general practitioners on referral patterns and initial diagnostic management of men with lower urinary tract symptoms in Italy: the Prostate Destination study.

OBJECTIVE: To assess whether adopting a shared protocol between urologists and general practitioners (GPs) might change diagnostic procedures and referral patterns in the management of men with lower urinary tract symptoms (LUTS). SUBJECTS AND METHODS: Forty-five urological centres and 263 GPs in Italy participated in this prospective study. Procedures adopted by GPs for evaluating five consecutive patients (aged > or = 50 years) were compared before (phase 1) and after (phase 2) implementation of the shared protocol. An evidence-based diagnostic algorithm was developed and approved by participating urologists and presented to local GPs at a training session. Protocol modifications were allowed after discussion with GPs. Direct costs of diagnostic procedures carried out before and after implementing the protocol were calculated from the perspective of the national health service. RESULTS: In all, 903 patients were evaluable in phase 1 and 856 in phase 2. Implementation of the protocol did not change referral patterns, with about half the patients being managed entirely by GPs. The use of a digital rectal examination by GPs increased from 32% to 41%, use of transrectal and suprapubic ultrasonography decreased from 33% to 23% and 53% to 44%, respectively, (all P < 0.001) and use of the International Prostate Symptom Score increased from 4.5% to 23.1% (P < 0.001). Overall, protocol-recommended tests were used more frequently, while those not recommended decreased after implementing the protocol. However, overuse of the tests not recommended (i.e. urine culture and free/total prostate specific antigen ratio) remained high. The mean cost per patient of diagnostic procedures ordered by GPs decreased from Euros 71.82 to Euros 61.93, with Euros 9.9 saved for each patient. CONCLUSION: Our intervention failed to decrease the percentage of cases of LUTS being referred to specialists, but was moderately effective in inducing changes in the diagnostic management by GPs that were indicative of increased compliance with best-practice principles, and produced cost savings of 13.8%.

Aged↗
PubMedDate not supplied

Mothers' parenting cognitions in cultures of origin, acculturating cultures, and cultures of destination.

Japanese and South American immigrant mothers' parenting cognitions (attributions and self-perceptions) were compared with mothers from their country of origin (Japan and Argentina, respectively) and European American mothers in the United States. Participants were 231 mothers of 20-month-old children. Generally, South American immigrant mothers' parenting cognitions more closely resembled those of mothers in the United States, whereas Japanese immigrant mothers' cognitions tended to be similar to those of Japanese mothers or intermediate between Japanese and U.S. mothers. This study provides insight into the nature of parenting cognitions generally and those of immigrant mothers specifically and therefore the parenting climate in which immigrant children are reared.

Acculturation↗
PubMed1998

Vasodilator component in sympathetic nerve activity destined for the skin of the dorsal foot of mildly heated humans.

1. Skin sympathetic nerve activity (SSNA) was recorded in seven male subjects from the peroneal nerve by microneurography, and the temporal correspondence of spontaneously occurring SSNA bursts with vasodilatation and sweating responses on the dorsal foot was studied during a mild body heating at rest. 2. Some SSNA bursts were followed by a sweat expulsion with a latency of 2.4 +/- 0.4 s, and some bursts by a transient vasodilatation with a latency of 2.2 +/- 0.4 s (means +/- S.D.). SSNA bursts followed both by a sweat expulsion and by a vasodilatation response (Type 1), those followed only by a sweat expulsion (Type 2) and those followed only by a vasodilatation, response (Type 3) were 70%, 10% and 1% of the total bursts examined, respectively. 3. For Type 1 bursts, there was a significant, but weak linear relationship among the burst amplitude, the amplitude of the corresponding vasodilatation and the amplitude of the corresponding sweat expulsion. 4. It was concluded that SSNA contains vasodilatory activity which is synchronous with sudomotor nerve activity. The results suggest that such vasodilatory activity contributes to sustaining the sweat gland function by supplying sufficient blood.

Adult↗