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Inflammation, pain, and chronic disease: an integrative approach to treatment and prevention.

Inflammation is now recognized as an overwhelming burden to the healthcare status of our population and the underlying basis of a significant number of diseases. The elderly generally bear the burden of morbidity and mortality, which may be reflective of elevated markers of inflammation resulting from decades of lifestyle choices. Lower cancer rates are associated with diets high in fiber, fruits, vegetables, and tea. AD and PD may be prevented or treated with aggressive vitamin E, curcumin, acetylcarnitine, and catechin supplementation. Cardiovascular disease, metabolic syndrome, hypertension, diabetes, and hyperlipidemia may be ameliorated by treating the underlying cause: inflammation caused by visceral adipose tissue. It is no longer appropriate to allow our dietary habits to contribute to the morbidity and mortality of the majority of humans. Although there is much more to understand, we have enough information presently to make the necessary changes in our lifestyles to significantly affect the inflammatory process and potentially live longer, healthier lives, with fewer burdens to an overburdened and failing medical system.

Antioxidants↗

[Chronic disease of the two sesamoid bones of the lower foot of the horse].

The aetiology and pathogenesis of navicular bone disease and sesamoidosis are discussed on the basis of findings reported in the literature and research. A marked similarity is found to be present between the clinical presentation, aetiology and pathogenesis of these two diseases. In addition, the intra and juxta-articular signs of degeneration as seen in these diseases are similar to those seen in various forms of arthrosis. Circulatory disturbances resulting from partial or complete arterial occlusion, caused by arteriosclerosis, are likely to play an important role in the cause of degeneration of various anatomical structures occurring in navicular bone disease and sesamoidosis. In contrast, it is unlikely that overloading is a major factor in the aetiology of navicular bone disease and sesamoidosis, although it may be of importance in its pathogenesis. For a full understanding of the cause of arteriosclerosis, far more fundamental research is required.

Animals↗