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Corneal transplantation in Alaska Natives (excerpts). 1975.

Since the time of the first corneal transplant in Alaska by Dr. Milo Fritz in 1958, great strides have been made in the field of corneal transplantation surgery. The introduction of fine 10-0 nylon sutures, the operating microscope, microsurgical instrumentation, and recently developed corneal preservation techniques has improved the prognosis in transplantation for all types of corneal disease, including PKC scarring. Our own experience at ANMC suggests that we should expect 80-90% of transplants performed for PKC to remain clear.

Alaska↗
PubMed2002

Population studies on three Native Alaska population groups using STR loci.

Allele distributions for 13 short tandem repeat (STR) loci D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, TH01, TPOX, CSF1PO and D16S539 were determined for three Native Alaskan population groups-Athabaskans, Inupiats, and Yupiks. Although genetic diversity is lower in the Native Alaskan populations compared with Caucasians and Africans, almost all loci are highly polymorphic in all three Native Alaskan groups. There was little evidence for departures from Hardy-Weinberg expectations (HWE) in any of the populations. Only two examples of detectable departures from HWE out of 39 locus-population tests performed were observed based on the exact test (Yupik, D8S1179, P=0.030; Yupik, D5S818, P=0.016). The F(ST) estimate overall 13 STR loci is 0.0309 for the Native Alaskan populations. Based on a genetic distance measure, Athabaskans are more closely related to Apaches and Navajos (all of the same linguistic group) than the other Native Alaskan groups. The F(ST) estimate for Athabaskans, Apaches and Navajos is 0.0180 and for Inupiats and Yupiks is 0.0167. The allele frequency data can be used for estimating DNA profile frequencies for Native Americans residing in Alaska.

Alaska↗