Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Sulfur Compounds”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 289 records · Page 16Linked to original sources
PubMed1985

New methods for the release of volatile sulfur compounds from human serum: its determination by Tenax trapping and gas chromatography and its application in liver diseases.

New methods are described for the release of sulfur volatiles from human serum or whole blood and for its determination by Tenax trapping and gas chromatography by use of a specific sulfur detector. Methanethiol (MT) is covalently bound in serum in at least two different ways. One fraction of MT is released by addition of acid and is covalently bound to a compound with a mol wt less than 500, probably as methyl-beta-D-thioglucuronide. Another fraction of MT is released by reaction with dithiothreitol and is covalently bound to proteins in a disulfide linkage. No significant differences were observed in the protein-bound MT fraction between normal individuals and patients with cirrhosis. In contrast, the acid-hydrolyzable MT fraction was significantly elevated (P less than 0.0001) in the group with cirrhosis (0.41 +/- 0.19 mumol/L, mean +/- SD, n = 39) compared with the normal group (0.22 +/- 0.04 mumol/L, n = 21). The acid-hydrolyzable MT fraction is excreted in the urine. The concentration in normal persons amounted to 9 to 37 mumol/L. Dimethylsulfide (DMS) was measured in whole blood. There was a close correlation between venous blood DMS concentration and its concentration in breath. Dimethyldisulfide was not present in detectable amounts in the blood of normal individuals. Ethanethiol was absent in the serum and blood of all studied subjects.

Breath Tests↗
PubMed1981

Use of reduced sulfur compounds by Beggiatoa sp.

A strain of Beggiatoa cf. leptomitiformis (OH-75-B, clone 2a) was isolated which is unique among reported strains in its ability to deposit internal sulfur granules from thiosulfate. It also deposited these characteristic granules (as all BEggiatoa species do) from sulfide. In cultures where growth was limited by exhaustion of organic substrates, these granules generally comprised about 20% of the total cell weight. With medium containing acetate and thiosulfate, no measurable utilization of thiosulfate or deposition of elemental sulfur (S0) took place until after the exponential growth phase. Neither sulfide nor thiosulfate added an increment to heterotrophic growth yield except for the weight of the deposited S0. The deposition of S0 from thiosulfate was probably a disproportionation in which S0 and sulfate were produced in a 1:1 ratio. Some of the S0 was further oxidized to sulfate. No autotrophic or mixotrophic growth was demonstrated for this strain. When inoculated in small, well-dispersed quantities into yeast extract medium, this strain grew only after long lags. Addition of the enzyme catalase eliminated initial lags and increased growth rates slightly. In contrast, catalase had no influence on growth rate when added to mineral medium containing acetate. In yeast extract medium, the inhibition of growth rate was presumably because of peroxides. Addition of thiosulfate was almost as effective as catalase in eliminating this inhibition. The S0 granules which, in this case, were deposited during the exponential growth phase, appeared to be partly responsible for this relief. This strain of Beggiatoa sp. remained active for at least 5 days under strictly anaerobic conditions, and under those conditions, it increased its dry weight by about 2.5-fold. Anaerobic "growth" and maintenance required the presence of an energy source, such as acetate. When cells containing much internal S0 were transferred to an organic anaerobic medium, a substantial portion of the internal S0 was eventually converted to sulfide.

Acetates↗