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PubMedDate not supplied

[Clinico-epidemiologic characteristics of superficial multiple basal cell carcinoma at the Dermatovenereology Clinic in Novi Sad 1986-1996].

INTRODUCTION: Multiple superficial basal cell carcinomas of the skin (MSBCC) appear as a rare clinical form of basal cell carcinoma (BCC) on the trunk. The aim of this paper was to display the clinical characteristics and frequency of superficial basal cell carcinomas on the trunk. MATERIAL AND METHODS: The examination was done on a 10-years material of the Department of Dermatological Oncology of the Dermatovenererology Clinic in Novi Sad (in the period 1986-1996). The examination included only MSBCC. RESULTS: In the 10-year period the total number of nonmelanotic malignant epithelial tumors of the skin (NMETS) was 2218 with 22 of MSBCC with total incidence of 0.99%. The average annual number of NMETS was 221.8. The average annual number of MSBCC was 2.2. In regard to the incidence of BCC of the skin in the same period, the total number of BCC of the skin was 1220, with the incidence of MSBCC 1.80%. The total number of changes of the superficial types BCC in the examined group was 110, and the average number of changes 5. The localization of MSBCC in the examined group shows the greatest number of tumors on the skin of the back (42--38.18%), hence thorax (29--26.36%), abdomen (25--22.73%) and the least on the presternum (14--12.73%). The average period from discovery of MSBCC in the examined group until the moment of inspection was about 2.5 years. In one case nevocellular syndrome was established, MSBCC was established in 35 patients, while in 80 cases these were different types of BCC of the face, capillitium, neck, trunk and extremitites. In the examined group 22.73% patients with positive familial anamnesis in regard to malignancy. Most were pensioners (11 cases--50.00%) mainly living in towns, while agriculturers are on the second place (7 cases--31.82%) mostly living in the village. In regard to the age, it appears that increasing number of patients are in the seventh decade of life. DISCUSSION: The recent literature data point to the genetic dispositions for MSBCC on the skin of the trunk, probably due to poorphotoexposition of the skin. CONCLUSION: Authors principally point to the genetic pre-disposition as the main etiological factor for MSBCC of the skin of the trunk. Professional or accidental photoexposition to ultraviolet radiation, also have a secondary role. The disease mostly affects the elderly and mostly males.

Aged↗
PubMed2000

The understanding of sadness, guilt, and shame in 5-, 7-, and 9-year-old children.

Children's understanding of sadness and guilt and of guilt and shame were examined in two separate studies, each involving a total of 60 Italian children aged 5-6, 7-8, and 9-10 years. For each emotion, the children were individually interviewed; they were asked to describe antecedents, thoughts characterizing the emotion that was the subject of the interview, and the action tendencies a person might use in response to the emotion. The children were also asked if, and if so, how, the presence of a parent might affect the emotion, and how they would cope with the situation. Results showed that at all the ages considered in this study, the children knew about the three emotions, although there were some age differences related to the depth of their understanding. Such data show that children's understanding of social emotions occurs earlier than claimed in previous studies that have focused mainly on antecedents.

Adaptation, Psychological↗
PubMedDate not supplied

[Occurrence of the metabolic syndrome in the population of the town of Novi Sad].

INTRODUCTION: Inadequate nutrition and physical inactivity are dominant health problems in general population resulting in high incidence and prevalence of noncommunicable diseases. Obesity (especially with central fat distribution), insulin resistance, hyperinsulinemia, hyperlipoproteinemia, dyslipoproteinemia and cardiovascular diseases are the main components of metabolic syndrome--Syndrome X. MATERIAL AND METHODS: Frequency of metabolic disorders characteristic for syndrome X are determined in a representative sample of Novi Sad town (1600 persons of both sexes, aged 25-64, of all professional levels). The response was 79.37%, so the sample included 1270 persons, in whom the following examinations were performed: history data, anthropometric measurements (height, weight, body mass index, weist to hips ratio), physical examination, blood pressure, biochemical analysis (fasting glycemia, oral glucose tolerance test (OGTT), total serum cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides). THE AIM: The aim of this research was to establish the frequency of obesity, types of obesity, glycemic status, disorders of glucose metabolism, disorders of lipid metabolism, frequency and type of hypertension, measurement of insulinemia and finally frequency of metabolic syndrome. RESULTS: The sample included 1270 persons. Among them 45.41% males and 32.64% females are obese. Extremely obese are 19.70% males and 27.12% females. W/H index > 1.0 was determined in 9.18% males while 48.82% females have W/H index 0.8-1.0. Fasting hyperglycaemia is present in 30.22% males and 20.86% females. Serum cholesterol > 5.20 mmol/l is determined in 74.96% males and 72.24% females. Arterial hypertension is diagnosed in 29.88% males and 23.40% females. In 82.75% persons of both sexes, aged 25-64, pathologic values among some of the followed-up characteristics are detected. In our sample syndrome X was suspected in 13.62% persons of both sexes (probability 50%) while 86.38% persons of both sexes are without risk for syndrome X (probability 70%). The best characteristic for dividing these two groups is W/H index (discriminatory coefficient 0.39). DISCUSSION AND CONCLUSION: In obese persons, especially in central obese persons, an active search for metabolic disorders which are present in syndrome X should be performed, because in that case measures of primary prevention can be applied.

Adult↗
PubMedDate not supplied

[Specificity of lipid and lipoprotein status in healthy students at the University of Novi Sad].

INTRODUCTION: The aim of this study was to determine the frequency of hyperlipoproteinemias and normolipidemic dyslipoproteinemias, and distribution of desirable, borderline and high-risk values of certain lipid status parameters in healthy young individuals. MATERIAL AND METHODS: In this investigation we examined 213 students of the University of Novi Sad of both genders, 20-30 years of age. Standard biochemical methods were used to determine values of total serum cholesterol, triglycerides, HDL cholesterol, and lipoproteins by cellulose acetate electrophoresis. The level of LDL cholesterol and LDL/HDL cholesterol and total/HDL cholesterol ratios were calculated. RESULTS: In this group hyperlipoproteinemia was established in 42.3% of cases and normolipidemic dyslipoproteinemia in 65.3%. Total serum cholesterol was minimally elevated in 39.0% of tested students, elevated with high risk in 3.3% and triglycerides were minimally elevated in 1.0%. Presence of elevated LDL cholesterol (24.4% minimally and 13.2% with high risk) is remarkably significant. HDL cholesterol is minimally decreased in 54.0% of tested students, and severely in 3.3%. DISCUSSION: The tested parameters deviate from desirable levels with an alarmingly high frequency, given the fact that this is a group of healthy young individuals with no previous history of lipid and lipoprotein metabolism disorders. It can be hypothesized that a joint hyper Lp(a)-lipoproteinemia can exist with a significant occurrence. These results could be associated with similar disorders in families of tested students, unhealthy food habits and lifestyle, use of oral contraceptives and smoking. CONCLUSION: Our results point to the need for performing gradual laboratory diagnostic procedures for routine check-ups in students.

Adult↗
PubMedDate not supplied

[Clinico-epidemiologic characteristics of Lyme disease treated at the Infectious Disease in Novy Sad 1993-1998].

INTRODUCTION: Borrelia burgdorferi, the etiological agent of Lyme disease, is transmitted by the bite of Ixodes ricinus, registered in all parts of Yugoslavia. Vectors are very active in spring and early summer and the disease has a seasonal distribution. Generally speaking, there are three defined stages of the disease, but some of them can be misdiagnosed or really absent. Serological analysis of Lyme disease is very difficult to interpret, especially in later stages, so confirmation by immunoblot assays is recommended. The aim of this study was to present some epidemiologic and clinical characteristics of Lyme disease in Vojvodina in the period from 1993-1998. Throughout this period, 1.659 persons with tick bite were registered, whereas 560 with diagnosed Lyme disease have been treated at the Clinic for Infectious Diseases in Novi Sad. RESULTS: In 511 patients (91.25%) we registered the first stage of the disease, in 42 (7.50%) the second stage and in 7 (1.25%) the third stage of the disease. The mean age of patients with erythema migranes was 38.67 years, mean incubation period was 9.37 days, and tick was removed from the skin after 2.29 days on average. Most of the identified tick bites originated from suburban areas (50.29%), they predominantly occurred in May and June (63.01%), and most of the ticks were removed improperly (57.67%). Dominant clinical manifestations of the second stage were acute meningitis (9.52%), Bannwarth's syndrome (9.52%), arthralgia and arthritis (50%), skin lesions (14.28%), cardiac disorders (11.90%) and mild liver lesions (2.38%) and generalized lymphadenopathy (2.38%). Chronic neuroborreliosis (42.85%), acrodermatitis chronica atrophicans (28.57%) and chronic arthritis were dominant clinical manifestations of the third stage. Up to 81.63% of patients with late stage of disease had a history of previous tick bite. One third of patients were asymptomatic in the first stage of the disease. Improper treatment of the first stage resulted in development of late stage disease in 57.14% of patients. CONCLUSIONS: Morbidity of Lyme disease in Vojvodina is about 1.98-9.8 cases on 100.000 inhabitants, and it belongs to regions with low incidence. Majority of bites are registered during summer months arround cities. Longer persistence of vector on the skin is a risk factor for manifested diseases. Inappropriately treated or completely untreated persons have higher risk for disseminated infection. In our country, most common manifestations of the second stage are neurological and articular manifestations as in the third stage. Leading symptoms and epidemiology aren't enough for diagnosis of Lyme disease, and more specific and sensitive serologic assays are necessary.

Adolescent↗
PubMed2002

Genetic diversity of the Novi Sad Wheat Core Collection revealed by microsatellites.

In recent years, considerable emphasis has been placed on the development of microsatellites to be used for a variety of objectives. Parental genetic diversity is a crucial requisition to derive desirable and superior progenies from crossing and selection. In order to determine desirable genotypes for hybridization, 710 wheat genotypes from the Novi Sad Core Collection, originating from 38 countries, have been evaluated during the 1993-2000 period. During those seven growth seasons, 54 agronomical, morphological, physiological and other traits have been evaluated in field and controlled conditions. In each year, the field experiment comprised 3-7 replications, while for each field replication the plot size was 1.2 m(2). Based on the results from this evaluation, 96 genotypes with the highest phenotypic variation for 26 of the very important traits for wheat breeding programmes in Yugoslavia and the UK, were identified for screening with microsatellites. A set of 36 microsatellite markers was used, covering all three wheat genomes and all 42 chromosomes. For the 36 microsatellites, a total of 46 loci and 366 alleles were detected, with the average number of 7.96 alleles per locus. For 35 loci, null alleles were detected. The association of microsatellite data with phenotypic data, for 6 important traits for wheat breeding (stem height, earliness, resistance to leaf rust and powdery mildew, sedimentation value and protein content), as well as the potential for their implementation in marker assisted selection (MAS) in wheat breeding programmes for both Yugoslavia and UK are discussed.

Alleles↗
PubMedDate not supplied

Are you often sad and depressed? Brief measures to identify women at risk for depression in pregnancy.

PURPOSE: The purpose of this study was to test brief depression screening measures as an initial step to identify women at risk for depression in pregnancy. STUDY DESIGN AND METHODS: Psychometric theory and a prospective correlational research design with a convenience sample of 130 low-income women guided this study. Measurements included (a) single-item depression-screening measures, (b) a two-item depression screening measure, (c) the Brief Depression Screen (BDS), and (d) the Beck Depression Inventory-II (BDI-II), a standardized measure of self-reported depression that has been used widely in pregnancy. RESULTS: Depressive symptoms in pregnancy among these low-income women were 27% (35/128) as determined by a score of 16 or greater on the BDI-II. The two-item depression screening measure, "Are you often sad and depressed?" and "Have you had a loss of pleasurable activities?" had a sensitivity of 91% and a specificity of 52%, whereas the BDS measure had sensitivity of 53% and specificity of 80%. CLINICAL IMPLICATIONS: Asking the two-item screening questions could be an essential first step in determining which women should receive further evaluation and interventions aimed at treating depression during pregnancy.

Adult↗
PubMed1992

[Epidemiological characteristic of basocellular skin epitheliomas treated at the Department of Dermatovenereal Diseases in Novi Sad].

The authors review some of the epidemiological characteristics of epithelioma basocellulare (EB) of the skin, showing the incidence of 2.39% of the cases treated for EB of the skin from 1984 to 1990, derived from the total of 61,384 initial examinations carried out in this period at the Department of Dermatovenereal Diseases in Novi Sad. The mean age of the patients was 64.42, the male-female ratio was slightly in favor of the females, 1:1.25. As for localization, EB of the skin were most frequently found on the face, head and neck (87.16%). Regarding occupation of the patients on the top were retired people (47.17%) and agricultural workers (33.02%) and regarding the place of living, most were found in the rural population (68.07). The mean time the treated patients came for a check-up was 1.26 year after the onset of the tumor. Relapses were found in 18 cases (1.23%). The mean time of their occurrence after the rtg therapy was 1.9 year. Familial predisposition for skin tumors was detected in 232 cases (15.79%).

Adult↗
PubMed1988

[" When I'm sad " Activities for adolescents living with different losses.].

In this article, the author relates an activity carried out with 209 adolescents. They were invited to write about circumstances surrounding sorrowful events. The adolescents mentioned events concerning mainly family and friends that made them very sad. Those who identified several sorrowful events at a time, namely family arguments, tend to be still affected when the author's survey tookplace. The author discusses in which way these events are related to loss, and how reactions are related to sorrow. Finally, the author suggests preventive assistance to young girls and boys in sorrow, with the help of peers, parents and the adolescent's own strengths.

English Abstract↗
PubMedDate not supplied

[Malignant ovarian tumors in childhood and adolescence in Novi Sad (1946-1989)].

In the period from 1946-1989, at the Department of Gynecology and Obstetrics University of Novi Sad, 79 ovarian tumors in children and adolescents were registered. There were 10 (12.6%) malignant tumours. The most common were dysgerminoma and carcinoma (total 6-7.6%). The treatment depended on the extent of the disease at the time of diagnosis (surgery, irradiation, chemotherapy or combination).

Adolescent↗
PubMed1991

[Growth, body weight and the yearly increase in height in children and adolescents in Novi Sad].

The paper presents a graphical account of the growth and nutritional status out of anthropometric values which were attained by means of a longitudinal study on Novi Sad children. The paper states the advantages which these graphical accounts provide through a quick, simple and exact evaluation of the growth and the nutritional status of children and young people from the second to the 18th year of age. The paper also gives nomograms of the annual height increase separately according to sexes. The average height of the eighteen-year old population (boys 179.8 and girls 166.5 cm) in our surroundings is among the highest in Europe. By comparing the named average height values with those of fifteen years ago we observe a positive difference in favor of today's young generation, this being 2.3 cm in boys and 2.0 cm in girls. The value of the T coefficient is 3.66 in boys and 3.7 in girls which means that the differences are very significant at the level of 1%.

Adolescent↗
PubMed1991

Stroke epidemiology in Novi Sad.

Since the organization of CINDI (Countrywide Integrated Non-Communicable Disease Intervention Programme) and MONICA (Monitoring of Trends and Determinants of Cardiovascular Disease) in 1983 over the whole territory of Novi Sad community it has been found that the incidence of stroke has decreased from 2.68 to 2.36%, the mortality from 67.1 to 42.2% and the number of registered stroke survivors (morbidity prevalence) has increased almost three times. The subjects, material and methods as well as the results obtained so far are presented in this paper.

Cerebrovascular Disorders↗
PubMed1990

[Allogenic transplantation of bone marrow in hematologic diseases. Preparation and completion of transplantation at the Hematology Clinic in Novi Sad].

The paper deals with the results of clinical preparations for the application of allogenic bone marrow transplantation at the Clinic of Hematology in Novi Sad. The obligation of the definite treatment of patients below 45 years by allogenic and autologous bone marrow transplantation results from the acceptance of the Yugoslav protocols for acute leukaemia treatment. Thus immunogenotypical analyses, so far performed in patients with severe aplastic anaemia have been extended to patients with acute leukaemia as well and then to patients with chronic myelogenous leukaemia, high risk lymphocYtic lymphoma and myeloma multiplex with resistance to standard chemotherapy and their potential sibling donors. The bone marrow transplantation Unit has been set up, the team of specialists has been formed and educated and the protocol for allogenic transplantation with Busulfan and cyclophosphamide combination for pretransplant conditioning has been adopted. In research work concerning the field of bone marrow transplantation a particular emphasis has been put on the working out of a mathematical model for optimal timing of bone marrow transplantation in patients with acute myelogenous leukaemia.

Adult↗
PubMed1989

[Menarche in schoolgirls in Novi Sad].

Out of 947 examined schoolgirls aged 8.5-15 from the two schools in Novi Sad, 327 of them had menarche. Arithmetic mean value of the appearance of menarche was 12.25 years, the standard deviation being 0.91 years. Median was 12.59 years. The normal appearance of menarche (X +/- 2 SD) ranged from 10.4-14.1 years in our environment. According to X2 (Chi-square) test and asymmetry coefficient (beta 1) it was pointed out that the distribution of menarche in examined schoolgirls was normal and symmetric.

Adolescent↗