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[Experience with Alpine's salicylamide].
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Quantitative structure-activity relationships of salicylamide neuroleptic agents.
The in vitro antidopamine activity of substituted N-[(1-alkyl-2-pyrrolidinyl)methyl]-6-methoxysalicylamides was found to be well correlated with the hydrophobic and electronic nature of substituents at the 3-position, and with the steric nature of groups replacing the hydrogen atom of the salicyl hydroxy group. In contrast, only the hydrophobic and steric characteristics were found to be important in the in vivo activity of these neuroleptics. This difference suggests that different mechanisms are probably involved in their in vitro and in vivo actions, and that the relevant receptors are slightly different in structure. The in vitro results suggest that electron donation by the 3-substituent strengthens the formation of a hydrogen bond between the carbonyl group of the amide moiety and a hydrogen of the receptor.
Proceedings: Bacterial degradation of salicylamide.
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QSAR on substituted salicylamides.
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[Studies on the synthesis of salicylamides and alkamine salts of niclosamide and their activities against Schistosoma japonicum and oncomelania].
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Proceedings: Bioavailability of salicylamide from tablets.
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Salicylamide glucuronide formation in newborns with severe jaundice of unknown etiology and due to glucose-6-phosphate dehydrogenase deficiency in Greece.
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[Biological-chemical mechanism of action of an anti-cestode drug N-(2'-chloro-4'-nitrophenyl)-5-chloro-salicylamide. 1. Modification of enzyme systems].
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[Contribution to the demonstration of some therapeutically applied salicylamide derivatives on silica gel layers].
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Dissolution rates of caffeine and salicylamide from tablets.
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Partition chromatography of barbiturates in combinations with salicylamide and other drugs.
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Differentiating nonaqueous titration of mixtures containing acetaminophen and salicylamide.
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Studies of the thermodynamics of dissolution, solubilization and micellar binding of salicylamide by a nonionic surfactant.
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[Development of glycuronoconjugation in twins treated with barbiturates. Studies in vivo with the salicylamide test].
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An investigation into the sedative properties of salicylamide.
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[Identification of drugs through their metabolic products such as phenacetin, salicylamides, carbamazepine].
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Gas-liquid chromatographic assay for salicylamide, acetaminophen, and caffeine mixtures, using on-line, computerized real-time data acquisition.
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