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Retrospective reporting of childhood adversity: issues in assessing long-term recall.

Much evidence for associations between adverse experiences in childhood and personality disorder in adult life comes from retrospective accounts. This raises important questions over the reliability and validity of long-term recall. The strengths and limitations of different methods for assessing the accuracy and stability of retrospective reports are discussed. Evidence from cognitive psychology on memory and memory processes, and on the phenomenon of infantile amnesia, provides important background for assessing issues more specific to recall in studies of risk for psychopathology. Here, topics of particular concern include: memory for traumatic early experience; the effects of mood state and symptomatology on recall; recovered or false memories; and the implications of mental representations of early experience for understanding psychopathology. Current evidence suggests that while adequately reliable accounts of many early experiences can be gained using appropriate techniques, further methodological studies are needed, and investigations using retrospective methods would be wise to include corroborative evidence whenever feasible.

Adult↗

Session duration and the VI response function: Within-session prospective and retrospective effects.

Two experiments examined the effects of session duration on responding during simple variable-interval schedules. In Experiment 1, rats were exposed to a series of simple variable-interval schedules differing in both session duration (10 min or 30 min) and scheduled reinforcement rate (7.5 s, 15 s, 30 s, and 480 s). The functions relating response rate to reinforcement rate were predominantly monotonic for the short (10-min) sessions but were predominantly bitonic for the long (30-min) sessions, when data from the entire session were considered. Examination of responding within sessions suggested that differences in the whole-session data were produced by a combination of prospective processes (i.e., processes based on events scheduled to occur later in the session) and retrospective processes (i.e., processes based on events that had already occurred in the session). In Experiment 2, rats were exposed to a modified discrimination procedure in which pellet flavor (standard or banana) predicted session duration (10 min or 30 min). All rats came to respond faster during the short (10-min) sessions than during the first 10 min of the long sessions. As in Experiment 1, the results seemed to reflect the simultaneous operation of both prospective and retrospective processes. The results shed light on the recent controversy over the form of the variable-interval response function by identifying one variable (session duration) and two types of processes (prospective and retrospective) that influence responding on these schedules.

Journal Article↗

Prevalence and location of acetabular sublabral sulci at hip arthroscopy with retrospective MRI review.

OBJECTIVE: The objective of this prospective study was to determine the prevalence and location of acetabular sublabral sulci diagnosed as variants at hip arthroscopy and to provide a retrospective MRI review. SUBJECTS AND METHODS: Two experienced hip arthroscopists noted the prevalence and location of acetabular labral sulci in 121 patients. The study population consisted of 57 males and 64 females with an average age of 43 years (range, 16-70 years). Of the 121 hip arthroscopies that showed sulci (22% of patients), correlation with the relevant MR studies (n = 27) was performed. Two radiologists who were aware of the arthroscopic findings reviewed the MR studies retrospectively, and agreement on imaging appearances was reached by consensus. RESULTS: Arthroscopy revealed 30 sulci (25%) in 27 of the 121 patients. In those who had a single sulcus (25 patients), 11 (44%) were located anterosuperiorly, 12 (48%) posteroinferiorly, one (4%) anteroinferiorly, and one (4%) posterosuperiorly. The other two patients had more than one sulcus: one patient had one posterosuperior sulcus and one posteroinferior sulcus; and the other patient had one anterosuperior sulcus, one anteroinferior sulcus, and one posteroinferior sulcus. In total, of the 121 patients, the number and position of the sulci were 12 anterosuperior (10%), 14 posteroinferior (12%), two anteroinferior (2%), and two posterosuperior (2%). Of the 27 MR examinations, 24 were unenhanced and three studies were performed after intraarticular injection of gadolinium. In these 27 patients, a total of 30 sulci were detected at arthroscopy. On retrospective MR review of both the conventional and gadolinium-enhanced studies, nine (75%) of the 12 anterosuperior sulci could be visualized. Ten (71%) of the 14 posteroinferior sulci were also identified. Neither of the two anteroinferior sulci could be seen. Both of the posterosuperior sulci were evident. Of the conventional MR studies, of a potential of 27, 18 (70%) were identified on conventional imaging. CONCLUSION: Sulci of the hip exist (22% of patients) and can be found at all anatomic positions (i.e., anterosuperior, anteroinferior, posterosuperior, and posteroinferior) of the hip. These sulci can be visualized on MRI with an accuracy of 70% using a nongadolinium technique.

Acetabulum↗

Comparison of flow cytometry and retrospectively applied static cytometry on lymphoid tissue.

Twenty cases of non-Hodgkin's malignant lymphoma were examined using both flow cytometry (FCM) and static cytometry (SCM) DNA analysis to detect aneuploidic cell populations. FCM was performed on fresh cell suspensions whilst SCM was performed retrospectively on formalin-fixed, paraffin-embedded samples of the same tissue. A total of 34 aneuploidic cell lines were detected by FCM compared to a total of 41 detected by SCM. Of the 20 cases 14 showed DNA indexes within 10% of each other for each method, indicating a reasonable degree of comparability between the two methods. Of the 6 cases which did not show comparable DNA indexes, 2 displayed similar cell lines for both methods, but the major abnormal cell populations were of different ploidy by SCM as compared to FCM. A qualitative comparison is thus possible between these two cases. The results suggest that retrospectively applied SCM ploidy analysis of lymphoid tissue is comparable to FCM on fresh tissue samples and can thus be used in retrospective studies of both prognostic and diagnostic significance.

Cytological Techniques↗

Simulations of a modified SOP model applied to retrospective revaluation of human causal learning.

Dickinson and Burke (1996) proposed a modified version of Wagner's (1981) SOP associative theory to explain retrospective revaluation of human causal judgments. In this modified SOP (MSOP), excitatory learning occurs when cue and outcome representations are either both directly activated or both associatively activated. By contrast, inhibitory learning occurs when one representation is directly activated while the other is associatively activated. Finite node simulations of MSOP yielded simple acquisition, overshadowing, blocking, and inhibitory learning under forward contingencies. Importantly, retrospective revaluation was predicted in the form of unovershadowing and backward inhibitory learning. However, MSOP did not yield backward blocking. These predictions are evaluated against the relevant empirical evidence and contrasted with the predictions of other associative theories that have been applied to retrospective revaluation of human causal and predictive learning.

Forecasting↗

Scale invariance in the retrieval of retrospective and prospective memories.

How does memory retrieval depend on time scale? One strong hypothesis is that such retrieval is scale-invariant (i.e., invariant across different time scales). To test this hypothesis, three groups of participants were given 4 min to recall what they did yesterday, last week, or last year (retrospective memories), and 4 min to recall what they intended to do tomorrow, next week, or next year (prospective memories). In line with scale invariance, retrieval performance was indistinguishable across time scales, for both retrospective and prospective memory. An additional finding was that significantly more prospective memories were recalled than retrospective memories, confirming previous observations of the "intention-superiority effect" (Goschke & Kuhl, 1993).

Adult↗

The role of segmentation in prospective and retrospective time estimation processes.

In five experiments, we investigated the effects of the segmentation level of an interval on its perceived duration. A prospective paradigm and an absolute time estimation method were used in two experiments, and in two others we used a retrospective paradigm and a comparative estimation method. A positive relationship was obtained between segmentation level of the estimated interval and its perceived duration under retrospective-comparative conditions for both auditory and tactual stimuli, but no relationship was found under prospective-absolute conditions. The paradigm, estimation method, and segmentation level were jointly manipulated in the fifth experiment. The impact of segmentation was significant under retrospective (both absolute and comparative) and close to significant under prospective-comparative conditions. These findings suggest that high-priority events are perceived and coded as contextual changes and that the impact of segmentation on time estimation is mediated by memory processes.

Adult↗

Age differences in memory for prospective compared with retrospective subject-performed tasks.

In two experiments, younger and older adults studied three lists of verbal phrases, each of the latter describing a simple action. One list was studied and recalled verbally; one was recalled verbally, but the actions were performed at study [retrospective SPTs (subject-performed tasks)]; and one was studied verbally and the actions were performed at test (prospective SPTs). With long lists, but not with short ones, retrospective-SPT recall exceeded verbal recall and older adults recalled fewer SPTs than did younger adults. Prospective-SPT recall did not exceed verbal recall at either list length, and in each of these prospective-SPT tests, older adults recalled fewer action phrases than did younger adults. Thus, it appears that when retrospective and prospective tasks are equated there are marked age differences that are generally consistent with the view that memory impairment in the elderly is more likely to occur in tasks that make higher attentional processing demands.

Adolescent↗

Conditioned inhibition produced by extinction-mediated recovery from the relative stimulus validity effect: a test of acquisition and performance models of empirical retrospective revaluation.

Empirical retrospective revaluation is a phenomenon of Pavlovian conditioning and human causal judgment in which posttraining changes in the conditioned response (Pavlovian task) or causal rating (causal judgment task) of a cue occurs in the absence of further training with that cue. Two experiments tested the contrasting predictions made by 2 families of models concerning retrospective revaluation effects. In a conditioned lick-suppression task, rats were given relative stimulus validity training, consisting of reinforcing a compound of conditioned stimuli (CSs) A and X and nonreinforcement of a compound of CSs B and X, which resulted in low conditioned responding to CS X. Massive posttraining extinction of CS A not only enhanced excitatory responding to CS X, but caused CS B to pass both summation (Experiment 1) and retardation (Experiment 2) tests for conditioned inhibition. The inhibitory status of CS B is predicted by the performance-focused extended comparator hypothesis (J. C. Denniston, H. I. Savastano, & R. R. Miller, 2001), but not by acquisition-focused models of empirical retrospective revaluation (e.g., A. Dickinson & J. Burke, 1996; L. J. Van Hamme & E. A. Wasserman, 1994).

Animals↗

Estimating mean time to reach a milestone, using retrospective data.

In surveys to estimate the mean age at menarche (or another milestone reached by the whole population), interviewed girls in the age range can respond that menarche (a) has not occurred or (b) has occurred or (c) occurred at a certain age t. Answers of type (a) and (b) are called status quo data. Answers of type (a) and (c) are called retrospective data.One kind of data is assumed. The distribution of age at menarche may also be assumed to be normal or not necessarily normal. This gives four possible sets of assumptions. Estimators, with their asymptotic distributions and optimal sampling allocations, are found for the case of retrospective data and non-normal distribution. These estimators are compared in examples with previously proposed estimators based on the other sets of assumptions. In these examples, retrospective data should certainly be used if available and reliable.

Adolescent↗

Thoracic cardiovascular imaging with 16-row multislice Computed Tomography and retrospective ECG-gating. Technical note.

PURPOSE: To apply the retrospective ECG-gating to the 16-row MSCT scan of intrathoracic vessels. MATERIALS AND METHODS: Fourty-eight patients underwent MSCT with a new 16-row scanner (Sensation 16-Siemens) for the study of the great intrathoracic vessels. In group 1 (33 patients) a retrospectively ECG-gated protocol was applied; in the control-group 2 (15 patients) a conventional MSCT protocol for thoracic imaging was applied. Images were scored regarding 1) the presence or absence of artefacts determined by breath-hold, beam hardening and mis-triggering; 2) the visualisation (optimal, mild and poor) of great intrathoracic vessels (aorta, pulmonary arteries and veins); 3) the visualisation (presence or absence) of proximal, mid and distal coronary arteries (left main, left anterior descending, circumflex, and right coronary artery). RESULTS: Ascending aorta showed motion artefacts in 3 (20%) cases in group 2 and none in group 1. In group 1, proximal LAD, CX, and RCA were assessable in 94%, 91%, and 91%, respectively. Left main coronary artery was assessable in 32 (97%) and 10 (67%) cases for group 1 and 2, respectively. In group 2, proximal segments of left anterior descending (LAD), circumflex (CX), and right coronary artery (RCA), were almost not assessable. CONCLUSIONS: The retrospectively ECG-gated 16-row MSCT provides more information regarding ascending aorta and coronary arteries.

Adult↗

Lymphomatoid papulosis in children: a retrospective cohort study of 35 cases.

BACKGROUND: Lymphomatoid papulosis (LyP) is a rare entity, considered to be part of the spectrum of the CD30(+) cutaneous lymphoproliferative disorders. About 10% to 20% of the adult LyP patients will develop an associated lymphoid malignancy. Only a few cases of LyP have been described in children, and the risk of associated lymphoid malignancies in these patients is not known. OBJECTIVES: To study the association between childhood onset of LyP and other malignancies and to determine the clinical characteristics in this subgroup of patients. DESIGN: Retrospective cohort study. SETTING: Referral center at a university hospital. Retrospective registry for patients with LyP of childhood onset (< or =18 years). Patients Thirty-five patients with childhood-onset LyP (19 boys and 16 girls) were interviewed by telephone using a standardized questionnaire. The median duration of follow-up was 9.0 years. All included patients were confirmed by histologic examination. RESULTS: The age distribution was significantly different, with boys having an earlier onset of LyP (P =.03). Of the 35 LyP patients, 3 (9%) developed a malignant lymphoma; all were diagnosed as having non-Hodgkin lymphoma. Compared with the general population, patients with childhood-onset LyP have a significantly increased risk of developing non-Hodgkin lymphoma (relative risk, 226.2; 95% confidence interval, 73.4-697.0). More than two thirds of the patients reported being atopic, which is significantly more than the expected prevalence of atopy (relative risk, 3.1; 95% confidence interval, 2.2-4.3). CONCLUSIONS: Lymphomatoid papulosis presents similarly in children and adults, including the risk of lymphoid malignancies. Therefore, all LyP patients should be closely monitored throughout their lives.

Adolescent↗

Cerebral outcome after extracorporeal circulation. Comparison between prospective and retrospective evaluations.

The cerebral outcome of 100 consecutive patients who had cardiac valvular replacement was evaluated by comparing the results of prospective neurological examination with retrospective data. The latter showed that the overall prevalence of cerebral abnormalities was 6% (4% among survivors) up to ten days postoperatively and 9% thereafter. This contrasts with the 35% (37% among survivors) obtained by careful neurological investigations that showed five patients with residual signs one year after operation. Electroencephalographic and neuropsychological studies disclosed additional patients who had subclinical involvement. The results question the reportedly ever-falling cerebral complication values claimed particularly in retrospective studies and reflect what is missed when using rough clinical criteria. There is no justification in overlooking slight clinical or even subclinical dysfunction, since the elimination of them is the only acceptable criterion of cerebral safety in cardiac operations.

Adolescent↗

Retrospective postmortem dementia assessment. Validation of a new clinical interview to assist neuropathologic study.

Neuropathologic studies of dementia and normal aging suffer from a lack of individuals examined for the presence and severity of dementia before death. To increase clinical information in such cases, a retrospective collateral interview was developed. Thirty-nine individuals were studied; 27 had autopsies. In all cases, the autopsy confirmed the Retrospective Collateral Dementia Interview (RCDI) diagnosis of the presence or absence of dementia; the RCDI had a sensitivity of 88% and a specificity of 80% for specifically detecting probable Alzheimer's disease. Agreement between the RCDI and premortem diagnosis was 96%; between RCDI and medical records, 100%. Agreement between RCDI staging of dementia severity and the last assessment of the living subject was 70%; between the RCDI and a brief staging at death, 86%. This validation confirms the value of postmortem interviews with close informants to assess dementia presence and severity.

Aged↗

512 rhytidectomies. A retrospective study.

A retrospective study of 512 rhytidectomy surgeries performed by one of us (F.M.K.) showed that the sequential technique and two-stage concept was used in most cases, with improvement in results noted when platysmal-superficial musculoaponeurotic system flaps were incorporated into the surgical routine. The majority of the patients were treated as outpatients; drains were rarely used. Statistical analysis of results and complications are discussed, as well as the aesthetic philosophy involved in this area of surgery. A comparison with other retrospective studies of this procedure is also given.

Adult↗

Retrospective analysis of the effect of interferon therapy on the clinical outcome of patients with viral cirrhosis.

BACKGROUND: Recent data suggest that interferon therapy (IFN) can reduce the risk of progression to hepatocellular carcinoma (HCC) in patients with hepatitis C virus (HCV)-related cirrhosis. METHODS: A cohort of 189 patients with Child's Stage A cirrhosis of viral etiology followed prospectively were analyzed retrospectively to assess the effects of IFN on the clinical course and development of HCC. RESULTS: During a mean follow-up of 71.5+/-23.6 months, 7.9% of 88 treated and 21.8% of 101 untreated patients showed worsening of the Child's disease stage (P < 0.01); 5.6% of treated and 26.7% of untreated patients developed HCC (P < 0.001); and 3.4% of treated and 19.8% of untreated patients died of liver disease or underwent orthotopic liver transplantation (OLT) (P < 0.005). Using Cox's regression analysis, no treatment with IFN, high bilirubin and alkaline phosphatase (ALP) levels, and low leukocyte counts and prothrombin activity (PT) were associated significantly with worsening of Child's disease stage; no treatment with IFN, long term disease, low albumin and PT, and high gamma-glutamyl transpeptidase (GGT) were related significantly to HCC development; and no treatment with IFN, low albumin and PT, and high GGT and ALP were associated significantly with reduced survival. After adjustment for independent risk factors identified by multivariate analysis, the estimated cumulative probability of worsening of cirrhosis (P < 0.05), development of HCC (P < 0.001), and death or OLT (P < 0.005) was significantly lower in IFN-treated patients compared with untreated patients. This beneficial effect of therapy was statistically evident only in HCV positive patients. CONCLUSIONS: These results support the hypothesis that IFN improves clinical outcomes and reduces progression to HCC in patients with HCV-related cirrhosis. These conclusions, based on retrospective data, should be confirmed prospective.

Adult↗

Reliability of an expert rating procedure for retrospective assessment of occupational exposures in community-based case-control studies.

The most daunting problem in community-based studies of occupational cancer is retrospective exposure assessment. To avoid the error involved in using job title as the exposure variable or self-report of exposure, our team developed an approach based on expert judgment applied to job descriptions obtained by interviewers. A population-based case-control study of cancer and occupation was carried out in Montreal between 1979 and 1986, and over 4,000 job histories were assessed by our team of experts. The job histories of these subjects were evaluated, by consensus, by a team of chemist/hygienists for evidence of exposure to a list of 294 workplace chemicals. In order to evaluate the reliability of this exposure assessment procedure, four years after the rating was completed, we selected 50 job histories at random and had two members of the expert team carry out the same type of coding, blind to the original ratings for these jobs. For 25 job histories, comprising 94 distinct jobs, the pair worked as a consensus panel; for the other 25, comprising 92 distinct jobs, they worked independently. Statistical comparisons were made between the new ratings and the old. Among those rated by consensus, the marginal distribution of exposure prevalence was almost identical between old and new. The weighted kappa for agreement was 0.80. Among items for which both ratings agreed that there had been exposure, there was good agreement on the frequency, concentration, and route of contact. When the two raters worked independently, the levels of agreement between them and between each of them and the original rating was good (kappas around 0.70), though not as high as when they worked together. It is concluded that high levels of reliability are attainable for retrospective exposure assessment by experts.

Adult↗

Impact of aorto-coronary graft markers on subsequent graft patency: a retrospective review.

The use of aorto-coronary graft markers has not been standard, presumably due to concern about possible adverse effects on subsequent graft patency. Our goal was to determine if there was any increased risk of graft occlusion in patients who received circumferential graft markers at the time of their coronary artery bypass (CAB) surgery. A retrospective review of angiograms was performed for patients with prior CAB. Cohorts with and without graft markers were compared. A total of 405 "unmarked" and 311 "marked" grafts were identified in 335 patients meeting inclusion criteria. Patency is reported in divisions of elapsed time since CAB. Overall patency in the "marked" group (71.1%) was significantly higher than in the "unmarked" group (58.0%, P < 0.001). In this retrospective population, there was no increased risk of graft occlusion in patients who received circumferential graft markers at the time of CAB surgery as compared to those patients who did not.

Anastomosis, Surgical↗