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[Reconstruction of chest wall defects with autogenous ribs grafts].

Three methods of chest wall reconstruction using autogenous rib grafts were reported. Fresh non-vascularized autogenous rib graft, vascularized autogenous ribs with muscle-flap, and pasteurized autogenous rib grafts were the materials used in these techniques. They are less convenient than those with artificial materials but afterwards physiologically more natural chest wall will be reconstructed. The third method (pasteurized rib graft) was applied to 22-year-old female with large recurrent desmoid tumor. Six resected ribs were heated in the saline at 60 degrees C for 30 min. and three of them were returned to the former position. Though tumor cells and bacteria are killed under this condition, these heated bone can be revascularized and replaced by normal bone as early as fresh non-vascularized rib graft.

Adult↗

Two quantitative methods for rib seriation in human skeletal remains.

Accurate rib sequencing is of importance to both forensic anthropologists and human osteologists, but until recently there have been few traits used to aid in the seriation of ribs within a human burial. This study examines two measurements (head to tubercle length and superior costotransverse ligament crest height) for the purpose of aiding rib identification and seriation in human skeletal remains. A sample of 344 ribs from 43 individuals from the 19th century Anglican Church cemetery of St. Thomas in Belleville, Ontario were used for the current study. While the head to tubercle length appeared unreliable for rib seriation, the superior costotransverse ligament crest height may provide an alternative technique for assessing rib sequence. More importantly though, the method provides a basis on which the identification of the central ribs can be made.

Adult↗

Analysis of the birefringence of a silicon-on-insulator rib waveguide.

A detailed analysis of the polarization characteristics (birefringence) of a silicon-on-insulator (SOI) rib waveguide is given. The fundamental TE- and TM-polarized modes of the SOI rib waveguide are calculated by a semivectorial finite-difference method. The rib width and the slab height of the SOI rib waveguide are normalized with respect to the total height of the silicon layer. A general relation between the two normalized parameters for a nonbirefringent SOI rib waveguide is obtained. According to this relation a nonbirefringent SOI rib waveguide can easily be designed. The fabrication tolerance for a nonbirefringent SOI rib waveguide is also analyzed, revealing that the tolerance can be increased by use of a larger total height of the silicon layer.

Journal Article↗

Development of Side Impact Thoracic Injury Criteria and Their Application to the Modified ES-2 Dummy with Rib Extensions (ES-2re).

Forty-two side impact cadaver sled tests were conducted at 24 and 32 km/h impact speeds into rigid and padded walls. The post-mortem human subjects were instrumented with accelerometers on the ribs and spine and chest bands around the thorax and abdomen to characterize their mechanical response during the impact. Load cells at the wall measured the impact force at the level of the thorax, abdomen, pelvis, and lower extremities. The resulting injuries were determined through detailed autopsy and radiography. Rib fractures with or without associated hemo/pneumo thorax or flail chest were the most common injury with severity ranging from AIS=0 to 5. Full and half thorax deflections were computed from the chest band data. The cadaver test data was analyzed using ANOVA and logistic regression. The age of the subject at the time of death had influence on injury outcome while gender and mass of the subject had little or no influence on injury outcome. Existing side impact injury criteria were evaluated such as Thoracic Trauma Index (TTI), Average Spinal Acceleration (ASA), full and half thorax deflections, chest velocity and viscous criterion, and contact force. The analysis results indicate that maximum normalized average half thorax deflection was the best predictor of AIS>/=3 and AIS>/=4 thoracic injury. TTI and upper spine accelerations were also good predictors of thoracic injury. Sixteen side impact sled tests were also conducted with the modified ES-2 dummy with rib extensions (ES-2re) under similar impact conditions as the cadaver tests. The rib extensions were added to the original ES-2 dummy ribs to prevent the "seat grabbing" action of the back plate that was noticed in some side impact vehicle crash tests with the ES-2 dummy. A separate analysis was conducted using the injury response and subject characteristics from the cadaver tests and the physical parameters derived from measurements on the ES-2re dummy in sled tests under similar conditions as the cadaver tests. This analysis provided thoracic injury criteria that could be directly applied to the ES-2re dummy. This analysis indicated subject age to have significant influence on injury outcome. Maximum rib deflection and ASA of the ES-2re were the best predictors of thoracic injury. A 50% risk of AIS>/=3 thoracic injury for a 45 year old corresponds to 44 mm (standard error range: 32 to 54 mm) of ES-2re maximum rib deflection and ASA of 46 gs (standard error range: 34 -58 gs).

Journal Article↗

Stress fracture of the eighth rib in a female collegiate rower: a case report.

OBJECTIVE: To present the case of a stress fracture of the eighth rib in a female collegiate rower. BACKGROUND: A female collegiate rower experienced severe pain in her chest, increasing with movement, deep breathing, and erect posture. No acute mechanism of injury was apparent. The team physician diagnosed a rib stress reaction based on clinical examination. The athlete rested for 2 days and then was able to resume rowing workouts. Five months later, she experienced the same sharp pain, with the diagnosis and treatment being the same. The athlete was able to compete in the championships 3 weeks later. At the end of the season, a bone scan revealed a stress fracture of the eighth rib. The athlete rested for 3 weeks and then returned to activity. DIFFERENTIAL DIAGNOSIS: Intercostal muscle strain, serratus anterior muscle strain. TREATMENT: Active rest, involving pain-free cardiovascular workouts and weight training, cessation of rowing until the athlete was asymptomatic, strengthening of dynamic support structures, and analgesic modalities. UNIQUENESS: Most stress fractures occur in the lower extremity. Those that do occur in the rib cage most often involve the first rib. A limited number of published works have addressed stress fractures to the remaining ribs; of these, posterior and posterolateral fracture sites are most often reported. This case is unique in that the fracture site was on the anterolateral aspect of the eighth rib. CONCLUSIONS: Stress fractures are thought to result from a variety of causes, including muscular fatigue, sudden changes in training intensity or duration, and microtrauma to bone at the muscular origin and insertion sites ("wear-and- tear" theory). In addition, hormonal factors in women can predispose an athlete with amenorrhea to a decrease in bone mineral content. Athletic trainers should be aware of these potential causes and focus on the prevention of stress fractures.

Journal Article↗

Application of fracture mechanics to failure in manatee rib bone.

BACKGROUND: The Florida manatee (Trichechus manatus latirostris) is listed as endangered by the U.S. Department of the Interior. Manatee ribs have different microstructure from the compact bone of other mammals. Biomechanical properties of the manatee ribs need to be better understood. Fracture toughness (K(C)) has been shown to be a good index to assess the mechanical performance of bone. Quantitative fractography can be used in concert with fracture mechanics equations to identify fracture initiating defects/cracks and to calculate the fracture toughness of bone materials. METHOD OF APPROACH: Fractography is a standard technique for analyzing fracture behavior of brittle and quasi-brittle materials. Manatee ribs are highly mineralized and fracture in a manner similar to quasi-brittle materials. Therefore, quantitative fractography was applied to determine the fracture toughness of manatee ribs. RESULTS: Average fracture toughness values of small flexure specimens from six different sizes of manatees ranged from 1.3 to 2.6 MPa(m)(12). Scanning electron microscope (SEM) images show most of the fracture origins were at openings for blood vessels and interlayer spaces. CONCLUSIONS: Quantitative fractography and fracture mechanics can be combined to estimate the fracture toughness of the material in manatee rib bone. Fracture toughness of subadult and calf manatees appears to increase as the size of the manatee increases. Average fracture toughness of the manatee rib bone materials is less than the transverse fracture toughness of human and bovine tibia and femur.

Animals↗

Rib fractures in 31 abused infants: postmortem radiologic-histopathologic study.

PURPOSE: To examine the morphologic alterations of fractures of the lateral and anterior rib arcs and costochondral junction (CCJ) to better understand the factors that influence radiographic visualization and to gain insight into the mechanism of injury in rib fractures of abused infants. MATERIALS AND METHODS: Thirty-one infants (average age, 3 months) who died with inflicted skeletal injuries were studied with high-detail, pre- or postmortem skeletal surveys, or both, and radiography of specimens, with histologic analysis. The distribution and number of fractures were determined for each technique, and dating was performed on the basis of radiographic and histologic criteria. The radiologic features were correlated with the pathologic findings in comparable histologic sections. RESULTS: Of 165 fractures, 84 (51%) involved the ribs. Only 30 rib fractures (36%) were visible with skeletal survey examination. Lateral and anterior arc fractures tended to impact along the inner cortex of the rib. CCJ fractures tended to involve the inner aspect of the osteochondral interface with an associated osseous fragment. CONCLUSION: Acute and healing rib fractures are common in infants who died with inflicted injury; detection is technique-dependent. Use of high-detail skeletal radiography to identify these injuries in live and deceased infants appears justified.

Autopsy↗

The first rib of hominoids.

Homo sapiens is unique among extant hominoids in displaying a univertebral articular pattern for the first rib; that is, the head of the first rib articulates only with the body of the first thoracic vertebra. All other hominoids, indeed virtually all other mammals, display a bivertebral pattern; that is, the head of the first rib articulates with the bodies of both the seventh cervical and the first thoracic vertebrae, as well as the intervening disk. Two fossil hominid partial first ribs, A.L. 288-lax and A.L. 333-118, show that the univertebral pattern was fully established in the hominid lineage by the appearance of Australopithecus afarensis. Four hypotheses, based in functional anatomy, can be postulated for the evolution of the univertebral pattern: (1), it increases the volume (via increased length) of the neck, which could, in turn, compensate for the functional loss of the laryngeal sac systems in hominid vocalization; (2), it is a consequence of the more barrel-shaped thorax in hominids; (3), it is a consequence of functional modifications in the hominid shoulder girdle; and/or (4), it is a consequence of modifications in hominid first rib motion while breathing in an upright stance. Fossil evidence supports all but the first hypothesis, and most strongly supports the third. However, evidence for the first hypothesis does suggest that the evolution of descent of the upper respiratory system in the hominid lineage may have been permitted by the presence of the univertebral pattern, while the reverse is probably not true. Furthermore, fossil evidence for the third hypothesis shows that, by the appearance of A. afarensis, the hominid upper limb had been freed from locomotor constraints, which concomitantly confirms full adaptation to upright posture. Thus, because of their potential relationship with upright posture, the two remaining hypotheses (i.e., "thoracic shape" and "first rib movement during breathing") also have support from the fossil evidence.

Animals↗

Brief communication: histological age estimation using rib and clavicle.

Histological methods for estimating age at death using osteon population densities for the rib, clavicle, and rib and clavicle combined are presented. Predicting formulas were generated from a sample of 40 individuals of known age, sex, and race. Independent samples of 12 ribs and 7 clavicles were used to test the formulas. Mean differences between known and predicted ages were 1.1 years, 2.6 years, and 3.4 years for the clavicle, rib and clavicle combined, and rib formulas respectively. An analysis of variance found no significant differences among the means for predicted and known ages. Since the formula based upon rib and clavicle combined has the higher standard error and r2, and includes data from different bones, it should provide better overall accuracy and reliability, and is recommended whenever both bones are available.

Adolescent↗

Independent test of the fourth rib aging technique.

The sternal surface of the 4th rib has been suggested as a useful predictor of adult age-at-death (Iscan et al.: Journal of Forensic Sciences 29:1094-1104, 1984; American Journal of Physical Anthropology 65:147-156, 1984). We tested its ability to do so in two tests. In the first, we developed a method of seriation and target age assignment for the 4th rib so that inaccuracy and bias of the method could be assessed by decade. We found that the 4th rib shows characteristic changes in morphology with age and can be included in multifactorial age estimates. In the second test, we applied the phase method developed by Iscan et al. (Journal of Forensic Sciences 29:1094-1104, 1984). The results of our three judges were generally similar to those reported by Iscan and Loth (Journal of Forensic Sciences 31:122-132, 1986). Measures of race differences in 4th rib morphology were included in both tests. Americans of African descent (black) showed a non-significant trend for the rib changes to be delayed compared to Americans of European descent (white). This is in contrast to the work of Iscan et al., which predicted that blacks would show a tendency toward accelerated rib changes compared to whites, especially after the early 30s (phases 5-7) (Iscan et al.: Journal of Forensic Sciences 32(2):452-466, 1987).

Adolescent↗

Inflammatory lesions of ribs: an analysis of the Terry Collection.

The aim of this paper is to consider the diagnostic criteria for tuberculosis in ancient populations. It investigates the frequency of periosteal new bone formation on the visceral surfaces of ribs from 1718 individuals from the Terry Collection, Smithsonian Institution, Washington D.C. and attempts to determine the aetiological factors producing these lesions. Numbers of individuals with lesions according to cause of death were recorded and the patterning of lesions compared between people who had died from tuberculosis and those whose cause of death was unrelated to a pulmonary disease. Rib lesions were more common in individuals dying from tuberculosis (61.6% or 157 of 255) than in individuals dying from other causes (15.2% or 165 of 1086). It is suggested that tuberculosis at a peripheral lung focus may disseminate directly through the pleura to the visceral surfaces of the ribs, or that pulmonary tuberculosis may be the cause of empyema of the pleural cavity and that this, per se, may initiate inflammatory change on the visceral surfaces of ribs. The nonrecognition or description of these often very subtle proliferative lesions on ribs by radiological examination of tuberculous victims is significant in the discussion of bone changes in tuberculosis. The possibility that individuals with no recorded history of tuberculosis at death actually suffered from the disease was considered in light of the frequency of rib lesions and noncorrelation with a tuberculous cause of death. Differential diagnoses are discussed including the possibility that the lesions represent a general non-specific indicator of stress.

Adolescent↗

The post-natal fate of supernumerary ribs in rat teratogenicity studies.

A common occurrence in rat teratology studies, supernumerary ribs, have been considered to be indicative of teratogenicity by some authors but not to be so indicative by others. As a teratogenic event is, by definition a permanent change, a study to follow the fate of supernumerary ribs in the development of adulthood of the rat was undertaken. An established teratogen in the rat, aspirin, was used to increase the frequency of supernumerary ribs. Even though aspirin treatment of the dams doubled the initial frequency of supernumerary ribs the results show that over the first 60 days post-partum their frequency in both control and treated groups decline to essentially zero. This decline in frequency of supernumerary ribs is complemented by an increase in the proportion of foetuses with a fully developed transverse process on the first lumbar vertebra. The proposal that supernumerary ribs in the rat are a result of developmental delays in a labile region of the axial skeleton and not a manifestation of a teratogenic event is presented.

Aging↗

Effects of intercostal nerve resection on the longitudinal rib growth in the growing rabbit.

Two, three, or four intercostal nerves with their vasoconstrictive sympathetic fibers were resected on the right side of 15 growing rabbits. Animals submitted to sham operations and intact animals formed two control groups. A scintigraphic study with 99mTc-methylene diphosphonate, performed on the test group 2 months after the resection, showed a significantly greater uptake of the isotope on the right than on the left costochondral junctions (p less than 0.05). Three months later the difference was still larger. There was no such significant difference in the rabbits of the two reference groups. In the rabbits of both these groups, the right and left ribs of each pair were almost equal in length. Of the denervated ribs of the rabbits composing the test group, the right ribs increased in length to a greater extent than the corresponding left ribs. The difference was statistically significant (p less than 0.05). As a consequence of this left-right difference in length, mild thoracic scoliosis convex to the left developed 2 months after the resection. The total weight and volume of the denervated right ribs increased significantly more than those of the corresponding control left ribs (p less than 0.05), but their mineral content per unit of weight or volume showed no significant difference.

Animals↗

The morphogenesis of beta-aminopropionitrile-induced rib malformation in fetal golden Syrian hamsters.

In order to provide information on the mechanism of beta-aminopropionitrile (betaapn) induced teratogenesis, the pathogenesis of a fetal rib abnormality was studied at relatively short time intervals following maternal treatment with 2,500 mg/kg aqueous betaapn on day 11 of gestation. Histochemical tests of ribs from betaapn-exposed fetuses indicated a slight decrease in the level of glycosaminoglycans but at a time when the defect was already morphologically established. Ultrastructural observations on the chondrocytes of ribs from betaapn-exposed fetuses revealed alterations in mitochondrial structure indicative of a slight cytotoxic effect for the teratogen. The mitochondrial changes were transient, occurring initially at three hours after treatment and lasting for nine hours. Alterations in the size of collagen fibres in the cartilage of the fetal rib were also observed in the offspring of betaapn treated females. The mean diameter of collagen fibres in the ribs of control fetuses increased throughout the course of the study. The mean diameter of fibres in the fetuses of betaapn-exposed females failed to show any increase and was found to be significantly less than controls as early as three hours following maternal administration. The results suggested that the principal factor in the production of the fetal rib deformity was fundamentally the same as that known to affect the adult; namely a defect in the extracellular maturation of collagen.

Abnormalities, Drug-Induced↗

Association of rib anomalies and malignancy in childhood.

A relationship exists between tumours and malformations both generally and in particular combinations. This is also valid for minor errors of morphogenesis suggesting that embryonic tumours are an expression of aberrant intra-uterine morphogenesis. We speculated that these minor aberrations might also manifest in other morphological defects, especially in minor anomalies and malformations of the ribs. We reviewed chest roentgenographs of 1000 children with malignancies for rib anomalies and compared them to 200 patients with mainly infectious diseases. We found 242 rib anomalies in 218 children with tumours (21.8%) and 11 (5.5%) in children without malignancy. This difference was statistically highly significant (P less than 0.001). A high incidence of cervical ribs was found in neuroblastoma (33%), brain tumour (27.4%), leukaemia (26.8%), soft tissue sarcoma (24.5%), Wilms tumour (23.5%) and Ewing sarcoma (17.1%). Only neuroblastoma showed a high incidence of rib bifurcation (4.5%). The increased incidence of these mesenchymal defects in children with malignancies may be another clue for an altered morphogenesis in tumour origin. In neuroblastoma the rib anomaly may be another expression of neurocristopathy as proposed for the association of congenital heart disease and neuroblastoma.

Adolescent↗

Rib resection for live-donor nephrectomy.

INTRODUCTION: Living-related kidney transplants yield more favorable results than cadaveric kidney transplant. Although multiple techniques have been described for living-related donor nephrectomy, operation is generally performed subcostally in lateral decubitis position or by an 11th or 12th rib resection. Recently laparoscopic donor nephrectomy is getting popular. The aim of this study is to determine the rib resection increase the morbidity or not. MATERIALS AND METHODS: Between 1997 and 2004 in our center 118 living donor nephrectomies were performed. 15 of these patients did not come to follow-up controls. This study consists of 103 patients: 11th rib resection (30 patients) determined as group I, 12th rib resection (52 patients) determined as group II, subcostal incision (21 patients) determined as group III. All these three groups were compared with each other according to operation time, pleural or peritoneal defect, pneumothorax, blood transfusion, wound infection, length of hospital stay, postoperative analgesic requirement, return to threshold activities and incisional hernia. RESULTS: Patients whose 11th rib was removed had the shortest operation time. But pain due to surgery continued more than others in this group of patients. The risk of developing incisional hernia was seen most in patients who had subcostal incision. In this group of patients incidence of incisional hernia was 4 (19%). None of the patients had wound infection. We also did not experience any pneumothorax and blood transfusion requirement. Peritoneal or pleural opening occurred in 4 out of 103 patients accidentally and there was no difference between groups. There was also no difference between groups in terms of returning back to daily activation. CONCLUSION: Morbidity of nephrectomy done with removal of 12th rib was less compared with other groups. Resection of 11th should be reserved for patients with high residing kidneys and also for those with a polar artery of the upper pole.

Adult↗

Periosteal chondroma of the rib: report of two cases.

We report two cases of periosteal chondroma of the rib, an extremely rare entity. The first case involved a 5-year-old boy who was admitted with pain and swelling around his left fifth rib. Surgery was performed in May 1999, and an 8 x 6 x 5 mm tumor was resected with the fifth rib. The second case involved a 39-year-old man with a 2-month history of cough who was referred to our department after a coin lesion had been detected on a chest roentgenogram. Physical examination on admission did not reveal any pain or tenderness. The rib tumor was resected along with the fourth rib by video-assisted thoracoscopic surgery and minithoracotomy in February 2000. The tumor was well encapsulated and consisted of an elastic hard mass measuring 22 x 15 x 13 mm. Both patients had an uneventful postoperative course and have remained well with no evidence of recurrence. Our review of the literature revealed only six previously documented cases of periosteal chondroma of the rib.

Adult↗

Subperiosteal rib-saving approach to kidney.

An operative approach to the kidney is described which takes advantage of the single attachment of the eleventh and twelfth ribs to their vertebral bodies, and an avascular plane that is present in the periosteal bed of the rib. By separation of the posterior attachments, the rib can pivot posteriorly and give a wide exposure of the kidney. By using an approach through the bed of the rib, the vascular supply to the intercostal space is avoided and less operative blood loss occurs. Saving the rib, rather than transecting it, avoids pleural and glove damage during the operation and adds a firmness to the wound not present when the rib is excised.

Humans↗