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Results for “Pergolide”

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At least 289 records · Page 16Linked to original sources
PubMed1999

Deterioration in parkinsonism with low-dose pergolide.

The administration of dopamine agonists can have a role early in the course of Parkinson's disease, in an attempt to reduce the frequency of long-term motor complications associated with the use of levodopa. After treatment with dopamine agonists has begun, gradual dose escalation is recommended to reduce the incidence of side effects; at low doses, parkinsonian symptoms significantly decline in some patients, only to improve as the dose increases. We report a number of such patients and discuss the possible pathogenesis of this motor deterioration.

Adult↗
PubMed2000

Sleep attacks (sleep episodes) with pergolide.

Increased sedation, somnolence, and sleep episodes seem to occur with several, if not all, dopamine agonists and dopaminergic treatment. Patients at risk of sleep episodes can be identified by well-chosen questions, and could be managed by appropriate measures including dose reduction.

Antiparkinson Agents↗