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[Laryngeal cancer and the history of laryngeal diseases and other diseases].

The diseases of larynx carcinoma suffered by 150 patients in the course of their all lives has been analysed. The results have been compared with a control group (150 patients with non-neoplastic diseases). Infectious diseases and others were taken into consideration. The statistical analysis proves that 80% of patients with larynx carcinoma have not suffered from infectious or other diseases. 90% of patients with non-neoplastic diseases have suffered from infectious or other diseases.

Adolescent↗

Laryngeal electromyography in the diagnosis of laryngeal nerve injuries.

A practical technique of electromyographic (EMG) sampling of the cricothyroid and thyroarytenoid (vocalis) muscles is described. Quantitative motor unit action potential (MUAP) analysis on a group of seven healthy subjects revealed a mean amplitude of 426 microV for the vocalis and 500 microV for the cricothyroid muscle. Mean MUAP duration for the vocalis muscle was 3.5 msec and 4.4 msec for the cricothyroid. Normal activation patterns are reviewed for each muscle. The results of EMG studies in 18 consecutive patients referred to the EMG laboratory with chronic hoarseness was reviewed. There was good agreement between findings at laryngoscopy and EMG, although more widespread involvement was seen on EMG than was suspected on the basis of laryngoscopy. Vocal cord immobility (apparent paralysis) was not usually accompanied by the total absence of MUAPs. The procedure was well tolerated without local anesthesia and provides information about peripheral nerves which may be of prognostic value.

Action Potentials↗

Laryngeal carcinoma--or is it laryngeal blastomycosis.

A patient is described who was evaluated for persistent hoarseness. Although an initial diagnosis of squamous cell carcinoma of the larynx was made, review of the pathology slides revealed pseudoepitheliomatous hyperplasia, acanthosis, and what appeared to be a fungal infection. After a detailed work-up was initiated the patient was treated successfully with ketoconazole for a blastomycosis infection of the larynx. The literature relative to blastomycosis infections of the respiratory larynx is reviewed. The authors emphasize that patients who show evidence of acanthosis and pseudoepitheliomatous hyperplasia along with the diagnosis of squamous cell carcinoma should be suspected as having a potential fungal infection.

Aged↗