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At least 289 records · Page 16Linked to original sources
PubMedDate not supplied

[Spermatic cord liposarcoma: differential diagnostic criteria and treatment].

OBJECTIVE: To report a case of liposarcoma of the spermatic cord in a young male, with special reference to the difficulties encountered in making the clinical and histopathological differential diagnosis. METHODS/RESULTS: A 43-year-old patient underwent surgery for a tumor (8 x 7 cms) in the left spermatic cord. Pathological analysis demonstrated a well-differentiated liposarcoma with myxoid areas. Radical orchidectomy was performed. The patient is well, with no tumor recurrence or metastasis. RESULTS/CONCLUSIONS: Paratesticular liposarcoma is rare. It is therefore difficult to establish the guidelines for treatment, prognosis and differential diagnosis. Similarly, difficulty is encountered when making the preoperative diagnosis, although US and CT can be useful. As in liposarcomas localized to other sites, the histological type and grade of the lesion are useful for the prognosis. Radical inguinal orchidectomy is the treatment of choice.

Adult↗
PubMed1999

[The patho-morphology and biological behavior of repeatedly recurrent liposarcoma in retroperitoneum].

OBJECTIVE: To investigate the patho-morphological features and biological behavior of repeatedly recurrent liposarcomas in retroperitoneum as well as the differential diagnosis with other malignant mesenchymal tumors. METHODS: Totally 10 patients accompanied with detailed clinical data. Except HE staining, immunohistochemical assays for S-100 actin, vimentin and myoglobin were also used for 32 specimens. RESULTS: 6/8 cases of the primary and 13/24 cases of the recurrent tumors of this group were diagnosed as sclerosing liposarcoma with spindle cell proliferation arranged in fascicles and whorls. Ten retroperitoneal tumor recurred within 20 months to 10 years, and among them, distant metastasis obtained only in one case. The histologic subtypes of recurrent and metastasized tumors became varied in 5 cases. CONCLUSION: Sclerosing liposarcoma was the most common histological subtype, see in retroperitoneal liposarcoma, local recurrence frequent, but distant metastasis rare. Surgical removal of the recurrent tumors might prolong the survival expectation of these patients.

Adult↗
PubMed2002

[Liposarcoma of the spermatic cord: case report and review of the literature].

Liposarcoma of the spermatic cord is rare and is usually discovered during hernia repair operation. We report a 71-year-old patient with spermatic cord liposarcoma. The patient presented with a painless mass in the left scrotum measuring up to 25 cm. The mass had gradually been enlarging during the last 6 months. Clinical examination suggested inguinal hernia and after a routine clinical check-up the patient underwent surgery. During surgery, a large, yellow, lobulated mass adherent to spermatic cord was found. The mass was not spreading to the retroperitoneum, epididymis or testis. Simple orchidectomy was performed. Histopathologic diagnosis was well-differentiated liposarcoma comprising foci of myxoid and dedifferentiated liposarcoma. At present the patient is well and without recurrence 6 months after surgery.

Aged↗
PubMed2002

[Local recurrence of liposarcoma of the spermatic cord 6 years after orchiectomy: a case report].

A 78-year-old man had undergone high inguinal orchiectomy because of a tumor of the right spermatic cord. Pathological diagnosis was pleomorphic liposarcoma according to the WHO classification. Adjuvant therapy was not performed because of advanced age. Six years later, he consulted our hospital with the chief complaint of asymptomatic swelling of the right scrotal region. Local recurrence was suspected, and tumorectomy was performed. Pathological diagnosis was pleomorphic liposarcoma with cartilaginous metaplasia. A review of 6 cases of recurrent intrascrotal liposarcoma reported in Japan, including the present case, revealed that 5 cases recurred locally in the same lesion and were growing slowly. Therefore, we considered that intrascrotal liposarcoma should be resected as extensively as possible and observed for a long period.

Aged↗
PubMed2002

[A case of liposarcoma of the renal capsule].

A 58-year-old woman was referred to our institution for treatment of a left renal tumor revealed by follow-up computed tomography (CT) of a pancreatic tumor. The CT showed a heterogeneous, perirenal mass containing areas of fat density. Angiography showed no feeding artery. Left nephrectomy was performed and pathological examination revealed a well-differentiated liposarcoma of the renal capsule. At the third-month follow-up, the patient was completely asymptomatic and free of recurrence. Primary tumors of the renal capsule are uncommon and liposarcoma of the renal capsule is distinctly rare. There have been only 17 reports of liposarcoma arising from the renal capsule in Japan. We, herein, report a case of liposarcoma of the renal capsule.

Female↗
PubMedDate not supplied

Liposarcoma of the breast: a case report and review of the literature.

Sarcoma of the breast constitutes <1% of all malignant breast tumors, and liposarcoma of the breast represents 3-24% of the primary breast sarcomas. We report a case of a 74-year-old woman presenting with liposarcoma of the left breast. The patient presented with a fibrous and hard mass measuring approximately 10 x 5 cm in diameter in the upper part of the left breast. Aspiration breast cytology showed inflammatory changes and had no malignant element. Differential diagnosis with sonography, computed tomography, and magnetic resonance imaging was not successful. A wide excision was performed with a 2-cm margin of healthy tissue. The tumor was diagnosed histologically as a well-differentiated liposarcoma (sclerosing type). The patient was discharged and her recovery was uneventful. We report a case of liposarcoma of the breast and discuss this rare malignant tumor and other types of sarcoma of the breast in light of the previously published literature.

Aged↗
PubMed2002

[Laryngeal and hypopharyngeal liposarcoma. Report of a case and literature review].

Liposarcoma is the second sarcoma of soft tissues more frequent in adult-age. Its localisation in head and neck is odd. The majority of liposarcoma, of this sitting, take its origin from soft tissues of the neck, being unusual primary liposarcoma from larynx and hypolarynx. Presentation of one case of liposarcoma of the larynx and hypopharynx and review of the opportune literature.

Aged↗
PubMed2003

[Liposarcoma of the pleura: an exceptional tumor. A study of two cases].

Primitive intrathoracic liposarcomas are rare tumors mostly located in the mediastinum or in lung parenchyma. Primitive liposarcomas of the pleura are exceptional and show a dramatic clinical course. These tumors are treated by surgery sometimes associated with radiotherapy. We report 2 cases of primitive liposarcoma of the pleura occurring in 2 women of 19 and 62 years of age. Histological examination showed in both cases a low-grade myxoid liposarcoma. In one case, ultrastructural study confirmed the diagnosis.

Adult↗
PubMed1992

[A case of mediastinal liposarcoma].

Primary liposarcomas of the mediastinum are rare neoplasms comprising only 0.13-0.75% of mediastinal tumors. We report a case of liposarcoma arising in the right posterior mediastinum. A 74-year-old man without symptoms was admitted to our hospital for evaluation of an abnormal shadow on chest roentgenogram. Computed tomogram (CT) and magnetic resonance (MR) imaging revealed a mediastinal tumor. The tumor was surgically removed, and the diagnosis of well-differentiated liposarcoma was established. MR imaging was superior to CT in evaluation of tumor extent, but not in differential diagnosis as liposarcoma or lipoma.

Aged↗
PubMed1992

[Liposarcoma of the transverse mesocolon--a case report].

Primary mesenteric liposarcoma is a rare neoplasm. We experienced a case of liposarcoma of transverse mesocolon. In our case, the examination of ultrasonography and CT scan revealed the tumor was solid and encapsulated. Preoperatively we suspected the tumor was malignant by the angiographic findings. Laparotomy revealed that the tumor was located in the transverse mesocolon and it could be removed easily. The histopathological diagnosis was myxoid type liposarcoma. It is said generally that liposarcoma is liable to recur after simple resection, therefore, we reconsider that we should have excised more extensively for this case. The patient is doing well without evidence of recurrence for 17 months after operation.

Aged↗
PubMedDate not supplied

Primary round cell liposarcoma of the omentum. A case report.

Liposarcomas are the most common of the malignant soft tissue tumors arising in the mediastinum and retroperitoneum. We have treated patients for round cell liposarcoma, an unusual histologic subtype, which is reported to be histologically mistaken for Ewing's sarcoma, lymphoma and other round cell neoplasms. The successful resection of a 2,300-g round cell liposarcoma of the omentum was recently performed at our hospital. Ultrastructural observations of this tumor are characterized by massive proliferation of the mitochondria in addition to the presence of lipid vacuoles in tumor cells. To our knowledge, no description of substantial mitochondrial proliferation in round cell liposarcoma has appeared previously in the literature; therefore, this is the first case report of histopathologic, cytopathologic and electron microscopic observations on this extremely rare tumor.

Female↗
PubMedDate not supplied

[Renal liposarcoma. Report of one case and bibliographic review].

OBJECTIVES: To report a new case of well-differentiated renal liposarcoma, and to describe its clinical features, diagnosis, treatment, and differences with other mesenchymal tumors of the retroperitoneum. METHODS: We perform a clinical review of renal mesenchymal tumors, especially liposarcomas. We report one case of well-differentiated renal liposarcoma in a 52-year-old female, and review current lines of treatment and follow-up. RESULTS/CONCLUSIONS: The well-differentiated renal liposarcoma is a very unfrequent mesenchymal tumor, for which it is necessary to know exactly its origin in the renal parenchyma. The treatment of choice is complete tumor exeresis; close follow-up should be exercised because even though it does not metastasize, local recurrences appear in 30% of the cases.

Female↗
PubMedDate not supplied

Large subcutaneous liposarcoma arising from the chest wall.

Liposarcoma usually occurs in the deep soft tissue of the extremities and the retroperitoneum. It rarely occurs in the cutaneous or subcutaneous tissues. We describe the case of a subcutaneous liposarcoma in a 63-year-old man, which arose from the chest wall. Magnetic resonance imaging showed a large subcutaneous tumor. Incisional biopsy revealed mature adipose cells with a slight variation in size and shape; no lipoblasts were observed. Therefore, at this stage we made the diagnosis of lipoma. However, the histological study of the tumor specimen subsequently obtained by surgery, showed mature adipose cells, atypical cells with bizarre nuclei, and lipoblasts with scalloped-shaped nuclei. We eventually diagnosed the tumor as a well-differentiated liposarcoma, adipocytic type (lipoma-like type). Patients with cutaneous and subcutaneous liposarcoma have a good prognosis, but there are reports of local recurrence after a long period, as well as high-grade change and dedifferentiation. Careful follow-up is required.

Humans↗
PubMed2005

[Multifocal liposarcoma showing rapid growth in a short term: a case report].

We report a case of multifocal liposarcoma that showed rapid growth in a short term. A 65-year-old male was referred from a local doctor to our clinic with the chief complaint of abdominal fullness. Abdominal CT shows two huge tumors in the intraperitoneal and retroperitoneal space, and we diagnosed it as multifocal liposarcoma. Both tumors were resected. The surgical specimens of intraperitoneal and retroperitoneal masses were 20 x 10 cm and 12 x 8 cm in size, and 3.5 kg and 2.8 kg in weight, respectively. Histological diagnosis of both tumors was myxoid liposarcoma. However, the tumor recurred 4 months later, and two additional operations were required because of rapid growth. The patient died at 7 months after the first admission. The clinical outcome of myxoid liposarcoma is known to be better than other histological types, but it is very poor when the tumor appears multifocally.

Aged↗
PubMed2006

Metastatic myxoid liposarcoma in the mesentery: what is debated? Case report and a review of the literature.

Myxoid liposarcoma, unlike other types of liposarcoma, has an unusual propensity to metastasize to extrapulmonary sites including the abdominal cavity. Metastatic myxoid liposarcoma is an important condition because it may indicate distant micrometastatic disease. We report the case of a 47-year-old woman with a metastatic myxoid liposarcoma in the mesentery. Surgical excision with a tumor-free margin was achieved, but cardiac and liver metastases developed. We review the available literature and discuss what is still debated about this disease.

Diagnosis, Differential↗
PubMedDate not supplied

Giant lesser sac liposarcoma mimicking infected pancreatic pseudocyst.

The most common site for abdominal liposarcoma is the retroperitoneum. We report a 32-year-old man with lesser-sac myxoid liposarcoma with extensive cystic degeneration. Cystogastrostomy was attempted elsewhere with a misdiagnosis of pancreatic pseudocyst. However, the procedure was abandoned after biopsy, which showed features of liposarcoma. The patient was re-explored at our institute 2 weeks later. Complete excision of the tumor was done. Histology revealed features of myxoid liposarcoma. The patient received adjuvant radiotherapy and is doing well 12 months later.

Adult↗
PubMed1990

[Utility of pre-operative imaging diagnosis in spermatic cord liposarcoma].

A case of spermatic cord liposarcoma was revealed by imaging diagnosis. The patient was a 59-year-old male, who consulted our clinic with the complaint of painless right scrotal swelling on June 30, 1989. One year earlier, he noticed this swelling, which was slow growing little by little. Palpation revealed a movable mass in right scrotum, 7 x 3 x 3 cm in size and separated from the right testis. Scintigraphy could not show RI accumulation and ultrasonography showed a capsulated homogeneous mass. Computed tomography (CT) and magnetic resonance imaging (MRI) showed capsulated fat-like almost homogeneous mass, which enclosed the right spermatic cord. This mass was suspected of spermatic cord lipoma or liposarcoma and was removed with radical orchiectomy. The weight of the mass was 246 g. This mass had a bunch of grape appearance and consisted of several masses of various sizes surrounding the spermatic cord, and could be separated from the right epididymis and testis. Histological examination revealed well differentiated liposarcoma and lipoma. Spermatic cord liposarcoma is very rare and this preoperative diagnosis is very difficult. Imaging diagnosis, such as CT, MRI may help our preoperative diagnosis.

Genital Neoplasms, Male↗
PubMed1985

[Liposarcoma arising from the renal capsule].

Liposarcoma is one of the most common soft tissue sarcomas, but liposarcoma arising from the renal capsule is rare. We report a case of liposarcoma arising from the renal capsule. Preoperative diagnosis was achieved by computerized tomography and and selective renal angiography. The tumor resected with he left kidney which weighed 4,370 g. Postoperative adjuvant chemotherapy with cyclophosphamide, bleomycin, actinomycin D, adriamycin and vinblastine was carried out. Although the patient's general conditions was fine, local recurrence occurred after 24 months postoperatively. Five cases of liposarcoma arising from the renal capsule including our case have been reported in Japan.

Antineoplastic Combined Chemotherapy Protocols↗