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Analysis of molecular data of Arabidopsis thaliana (L.) Heynh. (Brassicaceae) with Geographical Information Systems (GIS).

A Geographical Information System (GIS) is used to analyse allelic information of 13 sequenced loci of natural populations of Arabidopsis thaliana and to identify geographical structures. GIS provides tools for visualization and analysis of geographical population structures using molecular data. The geographical distribution of the number of variable positions in the alignments, the distribution of recombinant sequence blocks, and the distribution of a newly defined measure, the differentiation index, are studied. The differentiation index is introduced to measure the sequence divergence among individual plants sampled from various geographical localities. The numbers of variable positions and the differentiation index are also used for a metadata analysis covering about 26 kb of the genome. This analysis reveals, for the first time, differences in DNA sequence structures of geographically different populations of A. thaliana. The broadly defined west Mediterranean region consists of accessions with the highest numbers of polymorphic positions followed by the west European region. The GIS technology Kriging is used to define Arabidopsis specific diversity zones in Europe. The highest genetic variability is observed along the Atlantic coast from the western Iberian Peninsula to southern Great Britain, while lowest variability is found in central Europe.

Arabidopsis↗

Achieving change and altering behaviour through direct doctor use of a hospital information system for order communications.

Direct use of hospital information systems, and particularly of order communications systems by doctors, is central to the anticipated benefits from hospital information systems in Australia and other countries. There is an expectation that doctors will accept this technology and that the benefits will flow from their use. Concord Repatriation General Hospital in Sydney is one of very few hospitals in the world where doctors directly use a hospital information system to access patient information, place orders for diagnostic services and retrieve results. This paper reports on research which explored the nature of the direct doctor use of the hospital information system at Concord Hospital, and the changing attitudes of the doctors there.

Attitude to Computers↗

All Kids Count Connections: a community of practice on integrating child health information systems.

Integrated child health information systems consolidate data about multiple health care services a child receives into information useful to families, private health care providers, public health officials, and others. The challenges to successful integration faced by public health agencies are similar, yet system integration projects have historically struggled in isolation to overcome these barriers. All Kids Count created a community of practice called Connections to bring together 11 state and local public health agencies engaged in child health information system integration projects to learn from each other, capture best practices, and collaboratively address challenges. As demonstrated by All Kids Count Connections, communities of practice can be employed by geographically distributed public health agencies to address complex issues.

Child↗

MEDINFO--a medical information system.

The MEDINFO (MEDical INFOrmation) system is a general purpose computer-based information storage, retrieval, and analysis system. It is designed for a time sharing, on-line computer system for the rapid and easy creation, maintenance, and analysis of general data files. A wide variety of types of information may be used. These include numeric, categoric, text, date, and multiple-response. The file structure allows several sets of data, including date-orientated data, to be used. MEDINFO permits a study to be created, a description of the data made, data to be entered and updated into records, and for the data to be displayed or analyzed by the investigator without programmer intervention.

Computers↗

The development of NRMIS (Nursing Resources Management Information System)--Focused on patient classification.

Information system can be useful to effective and flexible decision making of nursing resource administration. A Nurse Resources Management Information Model and a Nurse Resources Management Information System (NRMIS) were developed in this study. The NRMIS consisted of a nursing staff scheduling system (NRS), a patient classification system (PCS), and an optimal nursing manpower estimating system (ONMES). The patient classification system was developed according to nursing intensity. The system was evaluated through user interface satisfaction and usefulness in the clinical settings. The main challenge is how we realize this information model to support evidence-based nursing resource administration.

Hospital Information Systems↗

[Hospital information systems or data processing in gynecology? Strategic reflections towards a comprehensive information concept].

Hospital information systems are essential tools for efficient hospital management and improvement of medical procedures. Structural differences between the management of hospital information systems and the management of other huge, distributed and heterologous information systems cannot be found. However, there are differences concerning special tasks in patient care and medical research with high demands in data protection and modularity. The management of information processing has to be performed systematically.

Electronic Data Processing↗

Understanding the dynamics of information technology implementation: a study of clinical information systems.

Health care institutions are considering a variety of emerging information technologies (ITs) in the hope of increasing efficiency, reducing costs, re-engineering work processes, and improving quality of care. The recent, rapid advances made in the use of innovative ITs in the health care field can present a plethora of problems to the administrative staff. Perhaps the most pressing of these concerns is the ability of today's hospitals to effectively create and utilize computer-based information systems. IT implementation has long been of great interest for information systems researchers. This branch of information system study seeks to identify those factors that are integral to optimizing the usage of IT. For example, researchers have advised practitioners that managerial support, high quality system design, commitment to advancing with the field, and extensive project planning are all key elements of successful system. In sum, previous research has produced a set of managerial proscriptions which, taken as a whole, constitute the "ideal" way to implement an IT system. Yet despite these normative principles and proscriptions, many health care institutions continue to find their attempts to make use of IT fraught with difficulty. Therefore, the objective of this study is to broaden and edify our understanding of IT implementation. More specifically, we seek to dispel the myth of the "ideal" system setup by exploring some of the alternative systems in use. We wish to investigate how and why the components of these alternative systems interact to produce utilization success (or failure). The study investigates the establishment and subsequent use of three clinical information systems (CIS) in a large tertiary care teaching hospital. The first case study is that of the hospital-wide implementation of a computer system that allows physicians to sign their medical records electronically. The second case examines the use of an electronic patient chart used to support the work of a variety of clinicians. Finally, we study a nursing assessment system used by two groups of nurses (intensive care unit and resuscitation unit) at a state-of-the-art, newly established Trauma Center. Qualitative was gathered through semi-structured interviews with people involved in the implementation process as well as a sample of user representatives. More than 90 interviews were conducted over a period of six months. Observational data completed our qualitative assessment. Quantitative evidence was gathered through questionnaires administered to a small sample of key informants. Three techniques of qualitative data analysis are being used in combination, namely, coding, analytical memos and displays. Data analysis is still in its infancy at this point. Regarding its relevance to the role of the administrator, this study will allow general and health care management as well as IT professionals to gain insight into the dynamics of the implementation of innovative technologies. In other words, results from this study will provide clear and relevant answers to the questions of how and why the outcome of the information system project is influenced by the way in which the technology is introduced.

Attitude to Computers↗

Using a geographical information system to plan a malaria control programme in South Africa.

INTRODUCTION: Sustainable control of malaria in sub-Saharan Africa is jeopardized by dwindling public health resources resulting from competing health priorities that include an overwhelming acquired immunodeficiency syndrome (AIDS) epidemic. In Mpumalanga province, South Africa, rational planning has historically been hampered by a case surveillance system for malaria that only provided estimates of risk at the magisterial district level (a subdivision of a province). METHODS: To better map control programme activities to their geographical location, the malaria notification system was overhauled and a geographical information system implemented. The introduction of a simplified notification form used only for malaria and a carefully monitored notification system provided the good quality data necessary to support an effective geographical information system. RESULTS: The geographical information system displays data on malaria cases at a village or town level and has proved valuable in stratifying malaria risk within those magisterial districts at highest risk, Barberton and Nkomazi. The conspicuous west-to-east gradient, in which the risk rises sharply towards the Mozambican border (relative risk = 4.12, 95% confidence interval = 3.88-4.46 when the malaria risk within 5 km of the border was compared with the remaining areas in these two districts), allowed development of a targeted approach to control. DISCUSSION: The geographical information system for malaria was enormously valuable in enabling malaria risk at town and village level to be shown. Matching malaria control measures to specific strata of endemic malaria has provided the opportunity for more efficient malaria control in Mpumalanga province.

Databases, Factual↗

A discharge planning patient information system.

A computerised patient information system aimed at improving the administration of discharge planning of patients with complex care requirements is described. The system was developed in two major acute general hospitals and has been operational since 1988. The system also transparently records key information about bed utilisation by patients awaiting a variety of discharge outcomes, including rehabilitation and permanent residential care. The extent of bed utilisation by patients awaiting residential care as measured by this system was compared with the results obtained by the conventional method of measuring this phenomenon in Australia--Nursing Home Type bed-days. The Nursing Home Type approach underestimated bed utilisation by this group of patients by 50 per cent, and failed to identify more than 60 per cent of the patients who were recommended for permanent residential care.

Aged↗

The reliability of the Massachusetts Substance Abuse Management Information System.

State substance abuse management information systems increasingly are becoming important tools for research, program management, and policy formulation at federal and state levels. These systems are currently undergoing radical expansion, leading to the creation of statewide performance and outcome monitoring systems for publicly-funded substance abuse treatment. This expansion makes imperative increased knowledge of the psychometric properties of the data in these systems. This study develops a method for examining the reliability of such data and applies it to the Massachusetts Substance Abuse Management Information System (SAMIS). Cohen's kappa, intraclass correlations, and the techniques of Heise (1969) are used to assess the reliability of different types of variables. Results show that key variables on the SAMIS Admission Form exhibit moderate to high reliability, supporting the use of this data for aggregate analyses. At the same time, caution should be used in making judgments about individual patients.

Adult↗

Linking genotype to phenotype: the International Rice Information System (IRIS).

The International Rice Information System (IRIS, http://www.iris.irri.org) is the rice implementation of the International Crop Information System (ICIS, http://www.icis.cgiar.org), a database system for the management and integration of global information on genetic resources and germplasm improvement for any crop. Building upon the germplasm genealogy and field data components of ICIS, IRIS is being extended to handle diverse rice genomics data including: genetic mapping, genome annotation, genotype, mutant, transcripteome, proteome and metabolomic data. Users can access information in the database through stand-alone programs and WWW interfaces offering specialist views to researchers with different interests.

Database Management Systems↗

Evaluation methodology for ambulatory care information systems.

The central purpose of an ambulatory care information system is to communicate information to the practitioner to facilitate clinical decision making. The clinical decision can be considered the dependent output variable in a process in which the information system, the patient, clinician characteristics and the environment are the independent input variables. Evaluation methodologies must consider there relationships. Approaches using patients outcomes are problematic because of indirect relationship between the information system and patient outcomes, which limits both sensitivity and validity. A process measure technique that focuses on the clinical decision directly as the measure of output could be appropriate if the represented a generic sampling of clinical decisions made in ambulatory care. A new method under development based on an information theory concept may be more widely applicable than currently available methods.

Ambulatory Care↗

Development and deployment of a health information system in transitional countries (croatian experience).

Croatian Primary Health Care Information System pilot project, conducted between 2001 and 2003, aimed to develop and deploy a health information system based on the latest technologies which would improve the quality of primary health care and rationalise the consumption. 60 primary health care teams (physician and nurse) were equipped with PCs and connected via central server to the main national health insurer, state treasury and public health institute. Developed information system enabled rapid retrieval of documents, replacement of manual data input and a real-time insight into needed information as well as prompt interventions within the system. The project also introduced electronic smart cards for physicians and nurses, so that at each medical check-up the information system verified both the ensuree's and the physician's or nurse's status and rights.Based on the experiences from the pilot project, plan has been made for comprehensive health information system at national level which would connect primary health care teams, hospitals, laboratories, dentistries, health insurance companies, state treasury, public health institutes and electronic health records database. Its major goals are more rapid diagnostics, accuracy in prescribing therapy, standardisation of the good practice as well as better utilisation of capacities, shorter waiting times and shorter stays in hospitals, which would lead to improvement in overall health care quality and better control over the health care consumption. Estimated 5-year investment for installing such system would be 125 million EUR. However, information system could save substantially more and yield a return of investment in only two years.As information system for primary health care should be a strategic component of every health care reform and development plan, we can recommend our model, based on the results of the pilot project, to other transitional countries.

Delivery of Health Care↗

Radiology information systems: looking to the future.

Radiology information systems will soon be able to help store and access digital images by interfacing with picture archiving and communication systems, and will include voice-recognition technology to speed up report transcription. Before these systems are molded to the technologic advances, however, they will likely be interfaced first with hospital information systems and upgraded to solve existing management problems in radiology departments.

Efficiency↗

The HELP hospital information system: update 1998.

The HELP hospital information system has been operational at LDS Hospital since 1967. The system initially supported a heart catheterization laboratory and a post open heart Intensive Care Unit. Since the initial installation the system has been expanded to become an integrated hospital information system providing services with sophisticated clinical decision-support capabilities to a wide variety of clinical areas such as laboratory, nurse charting, radiology, pharmacy, etc. The HELP system is currently operational in multiple hospitals of LDS Hospital's parent health care enterprise--Intermountain Health Care (IHC). The HELP system has also been integrated into the daily operations of several other hospitals in addition to those at IHC. Evaluations of the system have shown: (1) it to be widely accepted by clinical staff; (2) computerized clinical decision-support is feasible; (3) the system provides improvements in patient care; and (4) the system has aided in providing more cost-effective patient care. Plans for making the transition from the 'function rich' HELP system to more modern hardware and software platforms are also discussed.

Computer Systems↗

[The Flemish Information System Drugfree Centers].

The Flemish Information System for Drugfree Therapeutic Programs (VLIS-DC) is a computerised information system designed for residential treatment programs for drug addicts. The input is data from the therapeutic centers and the output is information for management, research and treatment. The system was installed in 1988. The final report for this first year has not yet been published, except for some preliminary results presented here. VLIS-DC generates information from clients admitted during 1988 in 8 departments in 6 centers for the whole Flemish region. Data of 623 admissions in these centers can be analysed. 411 were drug addicts (opiates, cocaine, amphetamines, cannabis, hallucinogens, solvents), 119 alcohol addicts and 75 addicted to medication. Of the total, 478 were daily users. The VLIS-DC is well functioning because all centers take part. Within a short time, more detailed information will become available from these centers.

Belgium↗

A preliminary conceptual framework for the design, development, and use of client-oriented information systems in health.

Client-oriented information systems (COIS) in the health care arena are defined and discussed. The antecedents of these systems, as well as current examples of the systems, are described. Prior studies in this area suggest content for COIS but demonstrate lack of a conceptual framework to guide the design, development, adoption, and use of these systems. The purpose of the paper is to suggest a preliminary conceptual framework for future study of COIS that draws upon concepts from the field of management information systems.

Community Participation↗