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[Feminine acne: dermatologic disease or endocrine disease?].

Acne is a problem of the pilo-sebaceous follicle caused by the conjunction of three factors: seborrhea, follicle obstruction, and follicle inflammation. The key element, seborrhea, is under androgenic control. Acne in women is also influenced by developments and modifications in genital life, as well as by hormonal contraceptive and replacement therapies. Acne is rare prior to puberty, when it may indicate endocrine disease. At puberty, acne is quasi-physiological, because of the relative hyperandrogenism induced by the andrenarche preceding pubarche, as well as by the relative shortage of estrogens and progesterone during the first menstrual cycles. Other signs of hyperandrogenism, such as menstrual cycle difficulties and excess weight, which favor a hormonal origin, must be sought in cases of persistent or late-onset acne in adults. There is a mirror image of puberty during the peri-menopausal period, but with decreased seborrhea, so acne is rare. Finally, a tumoral origin must be sought in the rare cases of acne occurring after menopause. Hormonal investigation of acne should not be systematic, but is justified during prepuberty when other symptoms are associated with acne that resists well-conducted dermatological treatment. The therapeutic approach should be primarily dermatological, but hormone-oriented treatment should be considered when such therapy fails, or in the presence of other signs of hyperandrogenism. Sometimes the association of isotretinoin and an anti-androgen treatment are necessary to effectively treat such acne. Finally, particular attention must be paid to contraceptive therapies and hormone treatments, which can induce or aggravate acne, especially during the peri-menopausal period.

Acne Vulgaris↗

[Feminine pseudo-hermaphroditism and ovarian polycystic syndrome: the role of hydrocortisone].

We report the case of a patient who was initially assigned as a male, and in whom the diagnosis of CAH was delayed (17 years of age). He was shown to have female pseudohermaphrodites. Before treatment, plasma testosterone level was: 15 ng/mL (N: 0.1-0.7), 17 OH progesterone (17 OHP): 45 ng/mL (N: 0.1-1.1) and FSH, LH values were below the normal range. While taking hydrocortisone, a rapid onset of new clinical, biological and radiological findings were observed after three months: rapid menarche and thelarche occurred, plasma testosterone and 17 OHP levels decreased, respectively 1 and 3.7 ng/mL, plasma FSH and LH were respectively 4.1 mUI/mL (N: 1.5-7) and 14.3 m UI/mL (N: 1.1-11.7). Polycystic ovaries were shown at sonography. Authors try to discuss the mechanism of the new events observed and specially those related to the polycystic ovarian disease. In a female with untreated CAH at adult age, menarche can rapidly occur once appropriate treatment was started.

17-alpha-Hydroxyprogesterone↗

Fat, fatigue and the feminine: the changing cultural experience of women in Hong Kong.

This paper seeks to demonstrate that rapid economic development in Hong Kong has transformed not only social structures but also Chinese women's subjectivity and bodily experience, thereby producing new forms of identity, aesthetics and aspirations, in addition to novel patterns of distress. Evidence is assembled to show that women's being-thin-yet-feeling-fat and being-active-yet-feeling-tired reflect not so much psychopathology as transformation in embodied moral experience. Because such normative experiences are grounded in the conflicting demands of production and reproduction that recent social transformations have brought to bear on women's lives, "fat" and "fatigue" can be said to embody what it is to become a woman in contemporary Hong Kong.

Adipose Tissue↗

A "feminine" model of vulnerability to depressive symptoms: a longitudinal investigation of middle-aged women.

The authors hypothesized that having traits associated with the female gender role is related to psychological distress in women. Specifically, they investigated the effect of low instrumentality and high expressivity, private self-consciousness, and anger-in on depressive symptoms measured 3 years later in 460 middle-aged women during the menopausal transition and times of stress. Multivariate analyses showed that after adjustment for depressive symptoms and educational level at study entry, depressive symptomatology 3 years later was higher among women who were low in instrumentality and high in self-consciousness at study entry. Women who were self-conscious were the most vulnerable to a subsequent ongoing stressor, and women who tended to suppress angry feelings and who used hormone replacement therapy when they were postmenopausal had more symptomatology than did other women. The study shows that midlife may be problematic for women with certain female gender role traits.

Adult↗

The dynamics of masculine-agentic and feminine-communal traits: findings from a prospective study.

A reciprocal impact hypothesis posits an influence of gender-related traits (agency and communion) on role enactment and a reciprocal impact of role enactment on gender-related traits, for both men and women. Specifically, in this study it was predicted that agency influences career success and career success influences agency. In addition, the reciprocal influence of communion and family roles was examined. A prospective study with almost 2000 university graduates, who were tested after graduation and 1.5 years later, clearly supported the reciprocal impact hypothesis for agency and career success. Communion influenced family roles, but there was no reciprocal influence. Implications for theories of career success and of sex and gender are discussed.

Adult↗

Feminine dimension in the play fighting of rats (Rattus norvegicus) and its defeminization neonatally by androgens.

In rats (Rattus norvegicus), juvenile males engage in more play fighting (a male-typical behavior) than do juvenile females, and this difference is based on perinatal influences of androgens. We show that there are qualitative and quantitative differences between the sexes in the type of defensive responses and their manner of execution. In defensive responses rats try to avoid having their napes contacted by the partner's snout. The sex differences arise from females' greater response distance; that is, females responded to an approach when the partner's snout was further from the nape. This permits females to use different defensive responses and to use them more successfully. This greater response distance is defeminized by the neonatal administration of testosterone propionate. Our findings suggest that play fighting in rats has both male- and female-typical features and that these are, at least in part, influenced perinatally by androgens.

Aggression↗