Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “CHRISTIANITY”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 289 records · Page 16Linked to original sources

Weber-Christian disease with benign cytophagic histiocytes in the skin lesion.

We describe an 8 year old female with Weber-Christian disease who manifested erythema on her legs and an intermittent high fever. A wedge skin biopsy revealed lobular panniculitis and bean-bag cells, which were characteristic to cytophagic histiocytic panniculitis (CHP). However, she showed no evidence of liver dysfunction, hyperlipidemia, or coagulation disorders usually seen in CHP. Moreover, she responded well to oral corticosteroids therapy with resultant advanced subcutaneous fat atrophy.

Adrenal Cortex Hormones↗

Generalized proteolysis in a young woman with Weber-Christian disease (nodular nonsuppurative panniculitis).

A patient with Weber-Christian disease (syn. nodular nonsuppurative panniculitis) is reported. The generalized cellular destruction in this patient resulted in liberation of proteolytic enzymes into the circulation, which led to multiple haemostatic disturbances with haemorrhagic diathesis. The most prominent haemostatic defects were thrombocytopenia with a normal life span of isologous platelets, high levels of AHF-related antigen, hypofibronigenaemia with short fibrinogen survival, low levels of Factor XIII (fibrin stabilizing factor = FSF) and increased amounts of fibrin/fibrinogen degradation products (FDP). Proteolytic enzymes, other than thrombin and plasmin which especially degrade Factor XIII and fibrongen, derived from destroyed cells (probably leukocytes) seem to have been involved in the pathogenesis of the bleeding disorder in this patient.

Adult↗

Dr Christian Kielland of Oslo (1871-1941) and his straight forceps.

Christian Kielland, a Norwegian obstetrician, published a description of his straight forceps in 1916. Although internationally recognised as a most valuable instrument for rotation of the fetal head, for many years his instrument received little appreciation in his own country.

Equipment Design↗

Weber-Christian panniculitis.

Two cases of Weber-Christian panniculitis with onset at 7 months and 3 years 6 months are described. Both show evidence of disturbances in immune mechanisms. The family of the first case has a high prevalence of coeliac disease, and the mother of the first patient also suffers from alopecia areata and dermatitis herpetiformis.

Child, Preschool↗

Myalgia as the major symptom in systemic panniculitis (Weber-Christian disease).

A case of systemic panniculitis (Weber-Christian disease) presenting with myalgia as the main clinical symptom is reported. There was no laboratory or electromyographic evidence of myogenic disturbance. Biopsy of the painful muscle revealed nonspecific mononuclear cell infiltration in the epimysial fatty tissue, while the muscle fibers remained intact. Prednisolone was dramatically effective in alleviating the myalgia as well as the other signs of panniculitis. The present case may indicate that myalgia in systemic panniculitis is one manifestation of its systemic connective tissue involvement.

Adipose Tissue↗

Growth hormone responses to growth hormone-releasing hormone in Hand-Schüller-Christian Disease.

Bolus doses of GH-releasing hormone (GHRH), 1 microgram/kg i.v., were given to two groups of adult patients with growth hormone deficiency (GHD): 9 with Hand-Schüller-Christian disease (HSCD, presumed hypothalamic GHD) and 9 with idiopathic GHD (IGHD, etiology unknown). Six patients in each group were then given further GHRH doses daily for 5 days, and the GH responses to GHRH were measured over 3 h on day 1 and day 5. Plasma levels of insulin-like growth factor-I (IGF-I) were measured twice daily on days 1 and 5 during GHRH treatment. All patients with HSCD had measurable GH responses to the first dose of GHRH, with a mean peak response of 6.4 +/- 2.1 ng/ml (mean +/- SE). Only 5 of 9 patients with IGHD had GH responses above the detection limits of the assay; their mean peak response, 1.3 +/- 0.2 ng/ml, was significantly lower than the GH responses of the HSCD patients (p less than 0.05). Responses in both groups of patients were lower than those previously observed in normal adult men (35 +/- 8 ng/ml; p less than 0.01). Five days of daily stimulation with GHRH significantly (p less than 0.01) increased the GH response in both groups of patients. The rise was greater in patients with HSCD than with IGHD (HSCD, 5.1 +/- 2.5 ng/ml on day 1, vs. 12.0 +/- 6.8 ng/ml on day 5; IGHD, 1.4 +/- 0.3 ng/ml vs. 2.9 +/- 0.6 ng/ml).(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Hans Christian Andersen's spelling and syntax: allegations of specific dyslexia are unfounded.

Sources contemporary with Danish author Hans Christian Andersen claimed that he did not master the Danish language, which modern studies interpret as specific dyslexia. A systematic study of his diaries from age 20 to age 70 found a mean spelling error percentage of approximately 1.7 (SD = 1%, range = 0%-4%). A methodologically independent reliability study confirmed these figures. Andersen's error percentages in poems and letters from ages 11 to 19 show a typical initial part of a learning curve that, together with the results from the diaries, gives a life span curve of his spelling development. The diaries, letters, and poems contain only insignificant syntactic errors. Andersen's spelling in the above studies is compared with that of his contemporaries and with data from modern studies. His mean error percentages at different ages are equal to the figures from nondisabled participants, but between 2 and 15 times lower than the mean percentages in studies of individuals with dyslexia. A structural analysis of Andersen's spelling errors shows that they are mainly phonologically plausible from ages 11 to 70, and that the proportions of plausible/implausible errors match those of normal achievers, but not those of individuals with dyslexia.

Age Factors↗

Hans Christian Andersen's visit to James Young Simpson.

Preparations are currently underway in Denmark for the celebration in 2005 of the 200th anniversary of the birth of that country's illustrious son Hans Christian Andersen. The renowned author of fairy tales had a passion for travel and recorded in his diary and in the several editions of his autobiography his encounters with the dignitaries and celebrities of his day. On this anniversary we recall the little-known occasion on which Hans Andersen was entertained to dinner and to a demonstration of the effects of inhalation of ether at the home of James Y. Simpson.

Anesthetics, Inhalation↗

Value of fibreoptic oesophago-gastro-duodenoscopy: experience with 4000 procedures at Kilimanjaro Christian Medical Centre, Moshi, Tanzania.

The paper presents the results of a retrospective study and the experiences with 4000 fibreoptic oesophago-gastro-duodenoscopies (EGD), which were performed at Kilimanjaro Christian Medical Centre (KCMC) between 1985 and 1989 in an open access service. Seventy per cent of all patients examined had abnormal findings with duodenal ulcer as the most frequent diagnosis (22%). Pyloric stenosis was seen in 6%, gastric ulcer in 5% and esophageal varices in 4% of all patients. High figures were found for carcinoma of the esophagus (4%) and malignancy of the stomach (5%). Gastritis was diagnosed in 11%. We consider fibreoptic EGD a cost effective and appropriate technology. Because of its high diagnostic yield, we advocate its use in certain centres in developing countries.

Adolescent↗

Christian social policy and homosexuality in The Netherlands, 1900-1970.

This essay explores the historical process in which homosexuality became an object for pastoral, medical, and mental health care in the Dutch Catholic community during the twentieth century. The confrontation between a moral-religious approach and the professional (medical and psychological) treatment of homosexuality is the central issue. In a continuing dialogue and a process of changing power relations between clergymen, physicians, psychiatrist, psychologists, and pedagogues as well as Catholic homosexuals themselves, homosexuality was transformed from sin and pathology into a psychological and social problem that could be treated in pastoral and mental health care. The changing attitudes of Catholics towards homosexuality can be explained in the context of the changing relations between religion on the one hand and health care on the other hand. Current viewpoints resulting from sociohistorical studies on the development of the medical and welfare professions have concluded that religion lost importance in modern society because physicians, psychiatrists, psycho-therapists, and social workers not only created new areas of intervention in people's private lives, but also took over the traditional tasks of the church in the field of charity and pastoral care. Medical anamnesis, psychoanalysis, and psychotherapy took the place of confession and pastoral care, thus the argument runs, and remission of sins and redemption were replaced by health and welfare. However, especially in the case of the development of the Dutch welfare state, there was a more complicated interplay between changing religious values and professional strategies. In the Netherlands professional health care and welfare institutions often were organized in a religious context and it is difficult to make a clear differentiation between religious and moral discourses on the one hand and medical and psychological ones on the other hand. Moreover, professional interventions did not take the place of pastoral care; it appears that pastoral care for homosexuals gained ground and was intensified after medical and psychological definitions of homosexuality had found acceptance in the Catholic community. Professional strategies did not supersede religion, but rather contributed to a moral re-orientation and a new pattern of Christian values and appreciations in the field of sexuality.

Attitude↗

The politics of counter-rejection: gay christians and the church.

This paper analyzes the accounts constructed by 60 gay male Christians in managing the stigma imposed on them by the Church. These accounts signify that they, having developed a positive self-image, are involved in the politics of counter-rejection of the Church and its official positions on the issue of homosexuality. Their counter-rejection of the Church as a moral arbiter is predicated on four bases: (1) the Church's ignorance of sex and sexuality, (2) the Church's ignorance of all sexualities as God's creation, (3) the Church's misinterpretation of biblical passages on homosexuality, and (4) the Church's fallibility. Having counter-rejected the Church by challenging its credibility, the counter-rejection of the Church's official positions is a matter of course. Their experiences highlight the ability of stigmatized social actors to invent social biographies not only to defend their moral choices, but also to challenge the credibility of sources that question and stigmatize their choices.

Adaptation, Psychological↗

Successful treatment of a patient with febrile, lobular panniculitis (Weber-Christian disease) with oral cyclosporin A: implications for pathogenesis and therapy.

We report a 15-year-old Japanese girl with severe systemic Weber-Christian disease (WCD) who presented with acute onset of high fever associated with tender subcutaneous nodules. Laboratory tests showed an elevated serum concentration of lactate dehydrogenase (LDH), leukopenia, and coagulation abnormalities. The anti-nuclear and anti-DNA antibodies were negative, and the serum pancreatic enzymes and alpha 1-antitrypsin levels were normal. Pulse steroid therapy was not effective, and eventually cerebellar hemorrhage occurred. After initiation of oral cyclosporin A (CyA) therapy, fever came down and her clinical condition improved markedly. Extremely high serum concentrations of interferon-gamma (IFN-gamma) and soluble interleukin-2 receptor (sIL-2R) in this patient returned to normal with CyA therapy. These findings suggest that T-cell immune responses are involved in the pathogenesis of WCD, and that CyA is effective against the disease via suppression of T-cell reactions.

Administration, Oral↗

Dyslipoproteinemia and an inhibitor of lipolytic enzymes in Weber-Christian disease.

Hyperlipidemia of initially Type V and finally of Type III was observed in a patient with Weber-Christian disease. The lipoprotein lipase (LpL) and hepatic triglyceride lipase (HTGL) activities of the post-heparin plasma were low, but detectable. Both lipase activities were higher when assayed with 20 microliters of post-heparin plasma than with more than 30 microliters, indicating the presence of some inhibitory factor in the plasma. This plasma inhibited purified LpL and HTGL from human post-heparin plasma. Zonal ultracentrifugation studies showed that the inhibitor of hepatic lipase was associated with the middle fraction of intermediate lipoprotein and low density lipoproteins (1.020 less than d less than 1.040). These results are consistent with the idea that dyslipoproteinemia in this patient was partially due to dysfunction of the catabolic system caused with an inhibitor of lipolytic enzymes.

Adult↗

Hand-Schüller-Christian disease with occult diabetes insipidus, cardiac failure and renal dysfunction.

A 60-year-old man was diagnosed as Hand-Schüller-Christian disease due to the triad of exophthalmus, decalcification of the bone, and diabetes insipidus. He had xanthogranuloma on the face and a nuchal region, and unusual complications of ADH-resistant diabetes insipidus due to renal dysfunction, and chronic cardiac failure. Urine osmolality was hypotonic, but urine volume was within the normal limit, despite the presence of central diabetes insipidus. Hypophyseal, adrenal and thyroid function were not remarkable. The skin biopsy showed the infiltration of eosinophilic granuloma cells. Treatment with vincristine was effective to regress the xanthogranuloma. Diabetes insipidus was not treated because of the absence of polyuria and polydipsia.

Acute Kidney Injury↗

Perception of alcoholism among Jewish, Moslem and Christian teachers in Israel.

This article describes a survey which investigated perception of alcoholism among Jewish, Moslem and Christian teachers in the north of Israel during the spring of 1991. Data were obtained from a sample of 553 teachers. The teachers were asked to agree or disagree with items associated with the disease concept or with the moral concept of alcoholism. The findings indicate differences in the perception of alcoholism among teachers of different religions, education levels, gender, and drinking practices. No differences were found among teachers of different ages or among those working in different types of schools.

Alcohol Drinking↗

Systemic form of Weber-Christian disease.

A case of systemic Weber-Christian disease, involving retroperitoneal adipose tissue with secondary damage to the associated organs and blood vessels is reported. The involved organs showed varying degrees of necrosis, lipogranulomata and fibrosis.

Adipose Tissue↗