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Pleuropulmonary actinomycosis associated with a systemic-to-pulmonary artery fistula and contralateral metastatic back mass.

We report a case of systemic-to-pulmonary artery fistula associated with thoracic actinomycosis and with metastatic hematogenous dissemination to the soft tissues of the back. The difficulty in diagnosing thoracic actinomycosis may predispose to the increased incidence of hematogenous spread of this disease. Although resection of pulmonary tissue including the infectious mass was required in previous cases, resection of the pleural mass alone was curative in this patient when combined with penicillin therapy.

Abscess↗

Cervicofacial actinomycosis following surgical trauma in rats.

Cervicofacial actinomycosis in man is often associated with physical trauma. The presence of intrabony abscesses in rat mandibles following surgical trauma supports the clinical observation that antecedent trauma is an important factor in the pathogenesis of cervicofacial actinomycosis.

Abscess↗

Periapical actinomycosis. An unusual case report.

An unusual case of actinomycosis in the oral cavity is reported. The strict anaerobic qualities of Actinomyces israelii make laboratory culturing and growing of this organism difficult. Accordingly, the diagnosis was based on the histopathologic report. Because of the atypical clinical presentation, i.e., lack of any discharging sinus tract on the skin surface, and the histopathologic reports, it was postulated that the actinomycosis was superimposed on an existing granulomatous tissue.

Actinomycosis↗

Cervicofacial actinomycosis resembling a ruptured cyst.

Actinomycosis, a chronic suppurative bacterial infection characterized by draining sinuses that discharge "sulfur granules," can mimic numerous other infectious and noninfectious conditions. We describe a 33-year-old woman with cervicofacial actinomycosis, which, on initial evaluation, was clinically and histologically diagnosed as a ruptured cyst.

Actinomycosis, Cervicofacial↗

Antibiotic treatment of cervicofacial actinomycosis for patients allergic to penicillin: a clinical and in vitro study.

The minimum inhibitory concentrations for erythromycin, clindamycin, lincomycin, tetracycline and minocycline have been determined for 92 clinical and three culture collection isolates of Actinomyces. From a consideration of MIC values and expected serum levels from oral therapy, minocycline was the drug of choice for the treatment of actinomycosis in patients allergic to penicillin. The serum levels of six patients allergic to penicillin, treated with oral minocycline 1 g/day were monitored and found to exceed the MIC for the Actinomyces species responsible for the condition. In all six Actinomycosis cases resolution was achieved in 8-16 weeks of oral minocycline therapy with no recrudescence for 1 year.

Actinomyces↗

Actinomycosis of the tongue. A diagnostic dilemma.

Actinomycosis of the tongue is an uncommon form of this well known but little seen bacterial disease. A review of the literature is presented and a report of a case which is believed to be the first from the British Isles in recent years. The clinical appearance mimicked a deep seated malignant tumour with induration, limitation of tongue movement and pain. A Tru-Cut biopsy was obtained which revealed a diagnosis of actinomycosis. Treatment was with oral phenoxymethylpenicillin for 3 months.

Actinomycosis↗

[Colonic actinomycosis: report of a case and review of the literature].

Actinomycosis is a chronic granulomatosis infection caused by a Gram positive anaerobic bacteria, Actinomyces. Abdominal localizations are rare and simulated a malignant process. The difficulties of diagnosis are usually leading to surgical resection. We report a colonic actinomycosis case of a 62-year-old woman with a abdominal tumor and diagnosed after surgical resection.

Actinomycosis↗

Actinomycosis complicating fibula flap mandible reconstruction: a report of two cases.

Two patients undergoing fibula flap mandible reconstruction developed chronic intraoral wounds and salivary fistulae. After initial attempts at salvage, tissue biopsies demonstrated Actinomycosis infection. With antibiotic treatment and debridement, one reconstruction was salvaged while one was lost. Actinomycosis infection should be considered a possible agent in chronic wounds complicating mandible reconstructions with microsurgical flaps.

Actinomycosis↗

Genital tract actinomycosis caused by Actimyces israëlii.

We report a case of actinomycosis caused by actinomyces israelii, related to the removal of intrauterine device (IUD). Diagnosing actinomycosis is difficult but should be considered in the event of any acute abdominal problems in a woman carrying an IUD. All abdominal organs may be affected. Even with a disseminated infection, the combination of appropriate antibiotic therapy (penicillin G) and surgery ensures a full recovery in most cases.

Actinomycosis↗

[Base tongue actinomycosis].

Actinomycosis is a bacterial, suppurative chronic infectious disease caused by Actinomyces israelii. Actinomycosis of the tongue is an uncommon form, and only 3% affect the base of the tongue. We report a case with dysphagia from an epiglottis, vallecula and tongue base mass. Diagnosis was made on histologic examination of a tissue biopsy. The disease completely resolved after chirurgical incision and drainage of the abscess and one month of oral amoxicillin therapy. The recurrence of the disease, five years later, made necessary a second surgical procedure and one year of penicillin therapy. We comment the possible causes of this recurrence.

Actinomycosis, Cervicofacial↗

Pelvic actinomycosis: a review and preliminary look at prevalence.

A review of the literature on pelvic actinomycosis reveals that actinomycetes normally reside in the female genital tract. Therefore the identification of actinomycetes in the vagina or cervix by any laboratory technique, including Papanicolaou smears with specific immunofluorescence or culture, is not diagnostic of any disease and is not predictive of any disease. The evidence strongly suggests that removal of the intrauterine contraceptive device of a patient with a positive culture is not necessary and that, in the absence of evidence for pelvic infection, antibiotics are not required. Pelvic actinomycosis is a rare disease whose pathogenesis is poorly understood.

Actinomyces↗

Actinomycosis of urachal remnants.

We report a case of urachal actinomycosis. The patient presented with complaints of micturition pain and a lower abdominal mass. Computerized tomography and an echogram showed the mass extending from the dome of the bladder to just beneath the rectus muscle. Exploration revealed a hard mass in the urachal cord, which was near the dome of the bladder and extended to the umbilicus. The mass and urachal cord were resected, and histopathological examination revealed actinomycosis of the urachal remnants.

Actinomycosis↗

Spinal intrathecal actinomycosis: a case report.

BACKGROUND: Actinomycosis of the central nervous system is a rare disease that most frequently forms cerebral abscesses. In the present report, we describe an extremely rare case of spinal intrathecal actinomycosis. CASE PRESENTATION: A 33-year-old man presented with high fever followed by back pain and paraparesis. Magnetic resonance imaging (MRI) with gadolinium-diethylene-triamine penta-acetic acid (Gd-DTPA) enhancement (Gd-MRI) displayed an irregularly enhanced mass lesion at the thoraco-lumbar junction that mimicked an intramedullary tumor with exophytic growth. Surgical exploration 7 months after the onset of the high fever revealed intrathecal granulation tissue with small abscess formation. Another surgical exploration was carried out 2 months after the first operation because the patient developed progressive paraparesis and showed an intrathecal ring-like enhancement that was detected with Gd-MRI. Actinomyces organisms were finally identified histologically in the surgical specimen. CONCLUSIONS: The clinical course and serial changes of Gd-MRI findings are important considerations when this rare and infectious spinal lesion is suspected.

Abscess↗

Primary actinomycosis mimicking urachal carcinoma.

We report a case of urachal actinomycosis that presented with a progressively enlarging infraumbilical mass associated with umbilical discharge. Computed tomography revealed an extraperitoneal mass involving the dome of the bladder. The possible diagnosis included a malignant urachal neoplasm or chronic inflammatory mass. Partial cystectomy and excision of the mass was performed. The pathologic examination revealed actinomycosis. The patient was treated with a 6-month course of antibiotics. No recurrence was noted 1 year postoperatively.

Actinomycosis↗

Pulmonary actinomycosis--a master of disguise.

Three cases of pulmonary actinomycosis are described. In all three cases, an initial diagnosis of pulmonary malignant neoplasia was made. The correct diagnosis was made histologically after the three patients underwent either lobectomy or pneumonectomy. All patients recovered after appropriate therapy. Pulmonary actinomycosis should always be considered in the differential diagnosis of pulmonary neoplasia, especially in young adults.

Actinomycosis↗

Actinomycosis: a potential complication of head and neck surgery.

Actinomycosis is a granulomatous infection occasionally found in the head and neck region that potentially may complicate a major head and neck oncologic surgical procedure. A case presentation, a review of the pertinent literature, and the treatment of this infectious complication are the primary elements of this report. A chronic infection of the neck caused by Actinomyces ssp developed postoperatively in a patient treated for head and neck cancer. Despite relapse after an initial course of long-term antibiotic therapy, the infection was successfully eradicated. Actinomycosis after surgery for head and neck cancer is unusual. However, the etiologic agent, Actinomyces ssp, is a common, potential microbial contaminant of head and neck surgery characterized by oral cavity or pharyngeal entry. Recognition of the typical manifestation of this infection in the neck facilitates prompt, appropriate treatment.

Actinomycosis↗

[Abdominal-pelvic actinomycosis with urinary tract involvement, secondary to gynecologic infection caused by intrauterine device].

Abdomino-pelvic actinomycosis is a condition caused by Actinomyces israelii, a Gram-positive opportunistic bacteria that triggers and develops the infection only in previously injured tissues, and then slowly progresses and spreads until it extrinsically affects the urinary tract. Use of an intrauterine device is a known risk factor to suffer from this disease. Relative risk in IUD users is two- to four-fold higher compared to IUD non-users. Risk increased with prolonged IUD use. Treatment is by removal of the causative agent, surgical resection of necrotic tissues and administration of intravenous Penicillin G, 4 million units every 4 hours for 30 days, followed by Amoxicillin 500 mg every 8 hours for 12 months. This paper contributes two cases of abdomino-pelvic actinomycosis with urinary tract involvement in IUD users. Standard treatment was employed with good evolution.

Actinomycosis↗