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Individual behavioural counselling for smoking cessation.

BACKGROUND: Individual counselling from a smoking cessation specialist may help smokers to make a successful attempt to stop smoking. OBJECTIVES: The objective of the review is to determine the effects of individual counselling. SEARCH STRATEGY: We searched the Cochrane Tobacco Addiction Group trials register for studies with counsel* in any field. Date of the most recent search: October 1998. SELECTION CRITERIA: Randomised or quasi-randomised trials with at least one treatment arm consisting of face to face individual counselling from a health care worker not involved in routine clinical care. The outcome was smoking cessation at follow-up at least six months after the start of counselling. DATA COLLECTION AND ANALYSIS: Both reviewers extracted data. The intervention and population, method of randomisation and completeness of follow-up were recorded. MAIN RESULTS: We identified eleven trials. Ten compared individual counselling to a minimal intervention, two compared two intensities of counselling, and one compared individual counselling to group therapy. Individual counselling was more effective than control. The odds ratio for successful smoking cessation was 1.55 (95% confidence interval 1.27 to 1.90). There was no evidence that more intensive counselling was more effective than brief counselling (odds ratio 1.17, 95% confidence interval 0.59 to 2.34). There was no evidence of a difference in effect between individual counselling and group therapy (odds ratio 1.33, 95% confidence interval 0.83 to 2.13). REVIEWER'S CONCLUSIONS: Smoking cessation counselling can assist smokers to quit.

Behavior Therapy↗

[Aggressive behaviour induced by apomorphine: relations with some elements of the behavioural profile and with the sensitivity to apomorphine (author's transl)].

Aggressive rats could be differentiated from non-aggressive rats on a lower rate of rearing reactions in the open-field activity, as well as on a weaker aptitude for learning, increasing with the complication of the test. The two groups of rats had comparable activity, and a comparable response to pain. Apomorphine decreased the number of rearing reactions and defecations on open-field activity in the same manner in non-aggressive rats as in aggressive animals. In the usual housing conditions, apomorphine increased similarly locomotor activity in both groups, but in observation cages of "emotional" type, the increase was much more pronounced in aggressive rats than in non-aggressive animals.

Aggression↗

Direct injection into the HPLC column for monitoring the behaviour of xenobiotics in biological media. II. Behaviour of cymoxanil in fungus and locust and of E-destruxin in locust.

Multidimensional chromatographies (MDC) implying either a single column with an unique packing designed for providing several separation modes such as internal surface reversed-phase (ISRP), or C1 large pores particles, or multi-column switching technique using the previous supports as guard columns, allow fast and easy direct monitoring of pesticides into plant or animal biological media. In such a way, the comparative study of the agricultural fungicide cymoxanil in two strains of Botrytis cinerea of different sensitivities gave concordant conclusions with the previous work using radiolabelled cymoxanil and TLC. Moreover, as a comparison, a study of the metabolism of this xenobiotic was also followed in animal biological fluids likely to contain peptidases. In locust or lobster haemolymph, an unusual isomerization into a cyclic compound was thus demonstrated accompanying the classical peptidase-depending metabolism generally observed in plants. The same chromatographic approaches were tested and compared for monitoring the metabolism of the natural insecticide toxin E-destruxin in insects. A detoxication process leading to the less toxic E-diol destruxin was evidenced in the organs or haemolymph of the locust Locusta migratoria chosen as a model of non-target insects.

Acetamides↗

Perceptions and behaviour among elderly hospital patients: description and explanation of age differences in satisfaction, knowledge, emotions and behaviour.

In this study, it is first of all investigated whether elderly and younger hospital patients differ with respect to satisfaction with several aspects of their stay in the hospital, medical and hospital knowledge, emotional state, seeking information, discussing problems and engaging in self-care. Second, it is investigated whether age differences on these variables can be explained by demographic variables, previous hospitalization experience, information received and personality characteristics on which elderly and younger patients differ. Results show that compared to younger patients, elderly patients are more satisfied, have less knowledge and a smaller number of emotional problems and are less active during hospital admission. These differences covary with, a more positive assessment of the information received, a stronger level of external control, a higher level of social desirability and stronger feelings of gratitude among elderly patients. These results are in line with Taylor's concept of the 'good patient'. Finally, based on the findings, measures are suggested for health workers to promote the well-being of elderly hospital patients.

Adolescent↗

Behavioural evidence that systemic morphine may modulate a phasic pain-related behaviour in a rat model of peripheral mononeuropathy.

In a model of peripheral mononeuropathy produced by 4 ligatures around the sciatic nerve, we investigated the effects of various i.v. doses of morphine on the vocalization thresholds elicited by paw pressure and compared the effects obtained with the same doses in normal rats. In neuropathic rats, morphine (0.1 and 0.3 mg/kg) produced a significant analgesic effect on the lesioned hind paw, maximum at 15 min post injection with a recovery at 20-25 min. For doses of 0.6 and 1 mg/kg, a modification of the kinetics was observed, with maximum effect at 20-30 min post injection and a recovery at 50-80 min. An analgesic effect was also observed on the unlesioned side, significantly less potent than that observed on the lesioned paw. The effect of 1 mg/kg morphine was almost totally reversed by a 0.1 mg/kg dose of systemic naloxone. The effects induced by the successive doses of morphine on the lesioned paw appeared higher than in normal rats (maximum vocalization thresholds (% of control) following 1 mg/kg morphine (N = 12) were 193.92 +/- 6.57% versus 154 +/- 3.5% in normal rats N = 3), whereas they were comparable to those obtained from the sham-operated paw. The present data clearly show that morphine induces potent antinociceptive effects in a rat model of neuropathy, which seems to contradict the classical view that neuropathic pain is opioid resistant. Some possible pathophysiological mechanisms are discussed.

Animals↗