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Results for “TICK FEVERS”

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PubMed1994

Sequential pathology of tick-borne fever.

The sequential pathology and clinical responses of 12 sheep infected with the Sourhope strain of Cytoecetes phagocytophila are described. During the experimental period of 3 weeks, the clinical effects were mild, as is usual. There was transient leucopenia, affecting mainly lymphocytes, eosinophils and neutrophils. Parasitaemia was detected from days 5 to 16, approximately. A mild but consistent histopathological response up to day 21 comprised (i) pulmonary alveolitis with minimal shedding of cells, (ii) follicular and especially parafollicular lymphoreticular reactions in lymph nodes and spleen, (iii) mesangial glomerulitis, and (iv) in the cranial nervous system marked choroiditis but minimal reaction in the brain. Two forms of intracytoplasmic inclusions were found, a smaller, granular basophilic structure occurring in clumps and an intravacuolar pleomorphic form. In tissue sections they were mainly associated with lymphoid and macrophagic cells. The significance of these findings is discussed including the problems of differential diagnosis in complex infections.

Animals↗
PubMed2004

Babesiosis of cattle.

Tick fever or cattle fever (babesiosis) is economically the most important arthropod-borne disease of cattle worldwide with vast areas of Australia, Africa, South and Central America and the United States continuously under threat. Tick fever was the first disease for which transmission by an arthropod to a mammal was implicated at the turn of the twentieth century and is the first disease to be eradicated from a continent (North America). This review describes the biology of Babesia spp. in the host and the tick, the scale of the problem to the cattle industry, the various components of control programmes, epidemiology, pathogenesis, immunity, vaccination and future research. The emphasis is on Babesia bovis and Babesia bigemina.

Animals↗