Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “THYROGLOSSAL CYST”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 271 records · Page 15Linked to original sources

Ectopic thyroid gland simulating a thyroglossal duct cyst: a case report.

There have been many reports of the inadvertent removal of an ectopic thyroid gland that was mistaken for a thyroglossal duct cyst. The differentiation of these two conditions is extremely important, because inadvertent removal of an ectopic thyroid gland may result in profound hypothyroidism. The authors report the case of a 5-year-old girl with an ectopic thyroid gland in whom the preliminary diagnosis was a thyroglossal duct cyst. They review the embryologic features in the development of an ectopic thyroid gland and discuss an approach to the management of this congenital anomaly.

Child, Preschool↗

Hypothyroidism following removal of a "thyroglossal duct cyst".

This case demonstrates how a midline ectopic thyroid gland can be misdiagnosed as a thyroglossal duct cyst. Awareness of this clinical entity is critical if the diagnosis is to be made preoperatively. Thyroid function tests and a 99mTc or 123I scintiscan of the neck should be performed when evaluating a patient with a midline anterior cervical mass. Although thyroid replacement will often cause regression of the enlarged ectopic thyroid gland, surgical intervention is required if a solid mass persists. When an ectopic thyroid gland has been excised and is subsequently found to be the child's only thyroid tissue, thyroid replacement is necessary. If biopsy of the mass established the diagnosis at the time of surgery, effective treatment consists of longitudinally dividing the tissue and placing each half laterally beneath the strap muscles. When this is done, long-term follow-up and periodic thyroid function tests are advised. If this tissue should become hypoactive, thyroid replacement is then required.

Child↗

[Cysts of the thyroglossal duct: analysis of diagnostic errors and causes of recurrence].

Thyroglossal-duct cysts usually present as an anterior midline neck mass, ranking first in this location in the pediatric age. We have carried out a retrospective revision of 52 pediatric patients with a preoperative diagnosis of thyroglossal-duct cyst. All of them were treated in our surgical unit between 1982 and 1989. The male to female ratio of cases was 34:18 with symptoms appearing at an average age of 4 years. The most frequent clinical presentation was that of a cystic mass without any inflammatory signs (65%), located in the mid-line at the hyoid level (75%). In this paper we analyze the existing possibilities as regards to the clinical presentation, location and characteristics of this type of cervical swellings, as well as the most frequent causes of misdiagnosis. We also make a comparison between the results we have obtained with the different surgical techniques used. We conclude that it is necessary to perform a radical surgical treatment of the thyroglossal-duct remnants, which includes removal of the middle third of the hyoid bone and excision of the thyroglossal duct as far as the foramen cecum.

Adolescent↗

[Papillary carcinoma in thyroglossal duct cyst].

OBJECTIVE: To report the management and outcome of three cases of papillary carcinoma (PC) in thyroglossal duct cysts (TGCs). MATERIAL AND METHODS: We present case reports of one male and two female patients between the ages of 30 and 38 years who had DTR cyst. In addition, we discuss the theories about the pathogenesis of DTR carcinoma (de novo versus metastatic lesions). RESULTS: In all three patients, we found a DTR that contained a vegetating mass. Subsequent pathologic examination revealed the presence of a PC. All patients underwent total thyroidectomy, and two of them concurrently had PC in the thyroid gland. Besides the PC in the TGC, the first patient had a "cold" scintigraphic thyroid nodule that was also a PC, whereas the second patient had a thyroid microcarcinoma that had not been detected before surgical intervention. The third patient did not have carcinoma of the thyroid. The patients received postoperative I131 and suppressive therapy with levothyroxine. During a follow-up period of 1 to 2.5 years (mean--1.75), we found no recurrence of the disease, and serum thyroglobulin remained undetectable in all cases. CONCLUSION: Although use of total thyroidectomy followed by radioiodine therapy and suppressive treatment with levothyroxine is a matter of debate in patients with PC in TGCs, we conclude that this approach yields a favorable outcome in most cases, especially when the thyroid is also involved by the PC, and allows a better postoperative follow-up.

Adult↗

Papillary carcinoma in thyroglossal duct cyst.

OBJECTIVE: To report the management and outcome of three cases of papillary carcinoma (PC) in thyroglossal duct cysts (TGCs). METHODS: We present case reports of one female and two male patients between the ages of 22 and 46 years who had TGCs. In addition, we discuss the theories about the pathogenesis of TGC carcinoma (de novo versus metastatic lesions). RESULTS: In all three patients, we found a TGC that contained a vegetating mass. Subsequent pathologic examination revealed the presence of a PC. All patients underwent total thyroidectomy, and two of them concurrently had PC in the thyroid gland. Besides the PC in the TGC, the first patient had a "cold" scintigraphic thyroid nodule that was also a PC, whereas the second patient had a thyroid microcarcinoma that had not been detected before surgical intervention. The third patient did not have carcinoma of the thyroid, but the histologic pattern of the gland resembled that observed in de Quervain's disease. We interpreted this finding as "palpation thyroiditis." The patients received postoperative 131I and suppressive therapy with levothyroxine. During a follow-up period of 2 to 12 years (mean, 5.8), we found no recurrence of the disease, and serum thyroglobulin remained undetectable in all cases. CONCLUSION: Although use of total thyroidectomy followed by radioiodine therapy and suppressive treatment with levothyroxine is a matter of debate in patients with PC in TGCs, we conclude that this approach yields a favorable outcome in most cases, especially when the thyroid is also involved by the PC, and allows a better postoperative follow-up.

Adult↗

Thyroglossal duct cysts: presentation and management in children versus adults.

OBJECTIVES: To determine if the clinical presentation of thyroglossal duct cysts (TGDC) varies between children and adults and whether this knowledge helps optimize the surgical management. METHODS: We retrospectively identified all patients with TGDC managed in our department between 1992 and 2002. We reviewed the patients' charts and recorded their gender, age at diagnosis, clinical presentation, radiologic imaging, surgical management, post-operative complications, and recurrence rate and compared the variables between the children and adults. RESULTS: Twenty-one children and 41 adults were treated for TGDC. Of the children, 57% were male and 43% were female, whereas 49% of the adults were male and 51% were female (P = 0.53). The average age was 6 +/- 5 years in children and 45 +/- 16 years in adults, which demonstrates a bimodal distribution. Forty-three percent of children and 42% of adults presented with an infected neck mass (P > 0.99). Among our patients, 96% of the adults and 100% of the children underwent a Sistrunk operation. Four children developed a wound infection that resolved with antibiotics. One adult developed a haematoma and another developed a wound seroma. There was one recurrence among adults and one among children, both of whom were treated with a second Sistrunk procedure. CONCLUSIONS: There appears to be a bimodal distribution for age at presentation of TGDC. Since the differential diagnosis among adults is broader, the opportunity for misdiagnosis is greater. However, once the correct diagnosis is made, the surgical management and post-operative outcome between adults and children is the same.

Adult↗

Ectopic thyroid gland in the submandibular region simulating a thyroglossal duct cyst: a case report.

The inadvertent removal of ectopic thyroid gland (ETG) that was mistaken for a thyroglossal duct cyst (TDC) leading to important hypothyroidism has been reported in the literature. The authors report the case of a 4-year-old boy with an ETG mimicking a normal TDC, in whom the preliminary diagnosis was a TDC. The diagnosis, the anatomic location of the ETG, and the management of this congenital anomaly are discussed.

Child, Preschool↗

Computer-tomographic appearance of branchial cleft and thyroglossal duct cysts of the neck.

The usefulness of computer tomography (CT) in the evaluation of a congenital neck mass has received little attention in the literature. We present the CT findings in two relatively common congenital neck masses - the thyroglossal duct cyst and the branchial cleft cyst. These cysts present a relatively common CT appearance of a mass with an enhancing capsule and a lucent center measuring between 20 and 35 Houndsfield Units. The branchial cleft cyst commonly occurs along the lateral border of the neck, anterior to the sternocleidomastoid muscle, while the thyroglossal duct cyst occurs along the midline of the neck. CT is excellent for determining the location, size, extent and character of these two common congenital neck masses.

Adolescent↗

Recurrent thyroglossal duct cysts: a clinical and pathologic analysis.

OBJECTIVE: To analyze, in detail, the clinical and pathological findings in a patient population that had undergone previous Sistrunk procedures for the removal of thyroglossal duct cysts, in order to identify any possible factors that could be related to recurrence after 'definitive' surgery. SETTING: A large pediatric tertiary care center. METHODS: A retrospective chart review was performed to include all patients treated at a single center for thyroglossal duct cysts with a Sistrunk procedure, between 1978 and 1992 inclusive. RESULTS: A total of 108 consecutive patients were analyzed. We noted that the presence of recent preoperative infection of the cyst was the only statistically significant (P < 0.05) clinical difference noted between the successful and the unsuccessful surgical groups. However, pathological analysis revealed that there was a substantially greater number of multiple thyroglossal duct tracts (P < 0.05) noted in the group that failed a Sistrunk procedure. CONCLUSIONS: We feel that multiple thyroglossal tracts may play an etiologic role in some recurrent cysts. Thus, a wide conservative excision, including the middle two thirds of the hyoid bone, is necessary in order to include any multiple tracts in the resection.

Canada↗

Follicular adenoma in a juxtathyroidal thyroglossal duct cyst with papillary carcinoma in the adjacent thyroid gland.

This patient presented with a neck mass diagnosed as a papillary thyroid carcinoma by fine-needle aspiration. Preoperative computed tomography revealed a papillary carcinoma within a juxtathyroidal thyroglossal duct cyst. After surgery, the initial diagnosis was papillary thyroid carcinoma. After correlation with the computed tomography, the diagnosis was revised to a papillary thyroid carcinoma plus a follicular adenoma in a juxtathyroidal thyroglossal duct cyst. This case demonstrates the need for close clinical and radiographic correlation in such a complex case.

Adenoma↗

[Thyroglossal duct cysts. Do prior inflammatory episodes influence the number of recurrences?].

INTRODUCTION: The most common complication in the treatment of thyroglossal duct cysts (TDC) is the high index of relapses. An analysis of this index and the influence of previous inflammatory episodes are presented. PATIENTS AND METHODS: A retrospective study of 120 consecutive TDC cases operated on during a period of 23 years, from 1972 to 1994, is presented. The statistical study was done using the Chi square test and the contrast of hypothesis for two proportions. RESULTS: The mean age of the patients was 4.9 years, with 93 cases (77%) being operated before 7 years of age. An inflammatory episode before surgery occurred in 57 cases (47%). Treatment was the Sistrunk technique in 112 cases (93%) and a simple excision of the cyst in 8 cases, with a relapse occurring in 4 of the latter cases (50%). Those cases where the Sistrunk technique was performed were divided into two groups: Group I (56 cases) those patients which had suffered an inflammatory episode before surgery and group II (56 cases) those that had not. Five relapses (8.9%) were found in group I and 2 (3.5%) in group II. CONCLUSIONS: TDC are fore frequent during early childhood, occurring most frequently before 7 years of age. The number of relapses are dramatically reduced when the Sistrunk technique is used, but no significant differences were found in those that had suffered previously an inflammatory episode.

Adolescent↗

Thyroglossal duct cyst with papillary carcinoma in an 11-year-old girl.

A case of primary papillary carcinoma arising in a thyroglossal duct cyst is reported in a young girl. This is a rare finding, with only five pediatric cases in the total of 115 cases reported in the literature. Subsequent management is described, including the role of scintigraphy and radioiodine ablation.

Carcinoma, Papillary↗

Preoperative thyroid scanning in presumed thyroglossal duct cysts.

The purpose of this study was to determine if preoperative thyroid scans are essential in the workup of presumed thyroglossal duct cysts. Questionnaires were sent to pediatric otolaryngologists and pediatric general surgeons with a 65% response rate. Fifty-seven percent of the physicians have encountered ectopic thyroid. In 58% of these, this was the only functioning thyroid tissue. Twenty eight percent of pediatric surgeons vs 65% of pediatric otolaryngologists routinely order scans. Two of the physicians encountering ectopic thyroid volunteered that they had successful litigation directed against them for removing the sole functioning thyroid and creating permanent hypothyroidism. There is a likelihood of encountering ectopic thyroid during the course of one's practice. A case of ectopic thyroid is presented, and management strategies are discussed.

Humans↗

Ectopic thyroid and Hashimoto's thyroiditis arising from a thyroglossal duct cyst: a case report.

A seventy-five-year-old male patient presented with a palpable smooth mass that moved upwards on swallowing, extending from the hyoid bone to the cricoid cartilage. Ultrasonography, scintigraphy, and thyroid hormone measurements showed the mass free from the thyroid gland. Following a diagnosis of infected thyroglossal duct cyst by fine needle aspiration biopsy, the mass was removed by surgery. Histopathologic diagnosis was Hashimoto's thyroiditis that developed from the ectopic thyroid tissue on the wall of thyroglossal duct cyst.

Aged↗

Cervical thymic cysts: CT appearance of two cases including a persistent thymopharyngeal duct cyst.

The differential diagnosis of cervical cysts in children includes common entities such as branchial cleft cysts, thyroglossal duct cysts, and cystic hygromas. Congenital thymic cysts are uncommon and often misdiagnosed as either branchial cleft cysts or cystic hygromas. However, they may have an appearance on CT that can be characteristic. The course of the descent of embryologic thymic tissue in the neck to the mediastinum indicates the potential site of deposition of an ectopic cervical thymic cyst. In a child, a cystic lesion that has an intimate relationship to the carotid sheath is likely to be a thymic cyst. Of the approximately 100 cases of vestigial cervical thymus or thymic cysts that have been reported in children, only 5 cases of a persistent thymopharyngeal duct cyst have been described [1-5]. In two of these five, the persistent thymopharyngeal duct cyst was demonstrated by CT [1,2]. We report one additional case of a cervical thymic cyst and one case of a persistent thymopharyngeal duct cyst both depicted by CT.

Child, Preschool↗

Congenital cystic dilatation of the submandibular duct.

A lesion which appeared clinically consistent with a ranula was explored surgically and found to represent a dilated submandibular duct. The differential diagnosis of cystlike swelling in the floor of the mouth should include sialolithiasis, mucous retention phenomenon (mucocele, ranula), dermoid and epidermal inclusion cyst, thyroglossal duct cyst, branchial cleft cyst, hemangioma, lymphangioma, cystic hygroma, lipoma, and occasionally pleomorphic adenoma. The case presented here demonstrates, both clinically and histologically, the cystic appendix-like appearance of a dilated submandibular duct manifest at birth. Reference is made to the limited number of similar cases noted in the relevant literature.

Cysts↗