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At least 271 records · Page 15Linked to original sources

Closure difficulty, figure-size expansion, and figure-size constriction on 240 Graham-Kendall Memory-for-Designs records.

To determine the frequency of occurrence of closure difficulty, figure-size expansion, and figure-size constriction, 240 university students were administered the Graham-Kendall Memory-For-Designs test. Subjects were volunteers enrolled in undergraduate psychology courses and were between 18 and 23 yr. of age, male or female, and U.S. citizens. The purpose was to define a sampling of drawing styles exhibited in a normal group on this test. Each drawing style, or factor, was treated as an independent variable, and the frequency of occurence of each level (dependent variable) was compared via chi square. It was noted that a significant number of subjects exhibited some degree of closure difficulty with the designs (X2 = 101.72, p less than .01). Figure-size expansion was noted as extremely rare for this sample (X2 = 444.78, p less than .01). Finally, extreme figure-size constriction occurred significantly more often than either moderate or no contriction of the designs (X2 = 62.58, p less than .01).

Adolescent↗

Multivariate analysis of litter size for multiple parities with production traits in pigs: II. Response to selection for litter size and correlated response to production traits.

Litter size and production trait responses to experimental selection for increased litter size in a Landrace pig population are reported. The numbers of sows and litters available for the first cycle of selection were 3,034 and 961, respectively. Selection was carried out using a BLUP repeatability animal model for number of piglets born alive (NBA). The experiment included one selection and one control line, each with three nonoverlapping generations. The selection line (H) consisted of the 160 sows with the highest breeding values and one boar from each of 25 full-sib families with the highest breeding values. The control line (C) consisted of 160 sows and 25 boars randomly chosen. The two subsequent generations in each line were obtained by random selection. A Bayesian analysis of genetic response using a multivariate model was carried out by Gibbs sampler. Marginal posterior distributions were obtained for direct response in NBA, and for correlated response in weight (WT), and backfat thickness (BT) at 175 d of age. The posterior means and posterior standard deviation (PSD) for direct genetic response of NBA ranged from 0.32 (PSD 0.08) in the first parity to 0.64 (PSD 0.08) in the fourth. The posterior means for correlated genetic response in WT and BT were -0.66 kg (PSD 0.36) and 0.20 mm (PSD 0.10), respectively. For WT and BT, the 95% highest posterior density regions (HPD) contain zero-correlated genetic response. Marginal posterior distributions of selection differentials were investigated. The posterior means for standardized selection differentials for NBA in different parities ranged from 0.70 (PSD 0.12) to 0.94 (PSD 0.06) in females for line H, from 0.22 (PSD 0.19) to 0.34 (PSD 0.10) in males for line H, and from 0.08 (PSD 0.08) to 0.13 (PSD 0.07) in females for line C. All available males were used in line C. Results from this experiment showed that selection for increased litter size is effective. Responses to selection were heterogeneous across parities, suggesting that litter size in each parity may have a different genetic background. No correlated genetic response to growth and backfat thickness was observed.

Adipose Tissue↗

High and low litter size trait and its relationship with serum and urine progesterone, serum zinc, and serum phosphorus in New Zealand white rabbits and improvement for the low litter size trait.

A number of does was classified according to their initial litter size to high (> 6 bunnies, group 1) and low (< 5 bunnies, group 2) in New Zealand White rabbits. Incidence of low litter size in the herd in the present study was 23%. The number of matings/conception, total mortality, corpora lutea/foetus, number and percentage of resorbed foeti were markedly higher in group 2 than in group 1. The litter weight, number of foetuses, implantation sites, and corpora lutea in group 2 showed a marked decrease over group 1. Serum and urine progesterone levels in pregnant rabbits of group 2 were significantly (P < 0.01) lower than in group 1, however, non-efficacious progesterone levels were significantly (P < 0.01) lower in group 2. The zinc content in serum, foetal dry weight and uterine horn dry weight, and serum inorganic phosphate in group 2 were significantly (P > 0.01) lower than in group 1. The litter size was significantly (P < 0.01) correlated with zinc and inorganic phosphate in group 2, while it was correlated with serum and urine progesterone in the two groups. The correlation coefficients were significant (P < 0.01) between urine progesterone and serum zinc and between serum progesterone and inorganic phosphate more frequently in group 2 during the gestation period than in group 1. The treatment of group 2 does with calcium carbonate, sodium phosphate dibasic, and zinc acetate in drinking water improved the serum progesterone, urine progesterone, and non-efficacious progesterone in addition to serum zinc and inorganic phosphate, which led to improvement of the number of matings/conception, litter size and litter weight, and lowered total mortality.

Animals↗

Size and size distribution of subfertile human spermatozoa.

An improved apparatus for measuring the electrical size (shape factor times volume) of particles based on the Coulter counter principle was used to characterize 110 subfertile semen specimens; size distributions were attainable in the 97 cases with a count above 1 x 10(6) spermatozoa/ml. The typical size distribution was unimodal and positively skewed. Spermatozoa maintained a constant profile during their passage through the orifice of the sizing apparatus, with an effective shape factor of 1.28. Two groups of cells were found. The larger one consisted of 68 specimens with a modal volume of 18.1 +/- 2.0 cu micron and a cell count of 27.5 +/- 9.2 x 10(6) spermatozoa/ml (mean +/- 1 SD). The smaller group contained 29 cases and had a modal volume of 6.6 +/- 0.9 cu micron and a count of 10.2 +/- 7.8 x 10(6). Samples with cell counts below 10 x 10(6) spermatozoa/ml tended to have low modal volumes (less than one-half the normal), but those above showed no particular trend.

Cell Count↗

Direct measurement of graft and recipient liver fossa size by computed tomography for avoiding problems due [correction of clue] to large graft size in living-related liver transplantation.

We investigated the incidence and manifestation of problems associated with large graft size in living-related liver transplantations and assessed the usefulness of determining volume and dimensions of the graft and recipient's liver fossa by computed tomography to indicate the risk. Five of 150 living related liver transplantations had grafts that were too large, resulting in difficulty in primary abdominal closure or in sudden worsening of hemodynamics during primary closure. No significant difference existed in recipient age, sex, body weight, selection of the graft segment, hepatic vein reconstruction, recipient resected liver weight, graft volumetry value, the ratio of body weight of donor relative to recipient, and the percentage of graft weight relative to recipient body weight, between the groups with and without these problems. Mean +/- SEM of maximal dimensional ratio, defined as the maximum of the ratios of 3 dimensions of the graft relative to recipient liver fossa, were 2.36 +/- 0.64 for patients with grafts that were too large and 1.00 +/- 0.02 for the cases without size problems. The mean +/- SEM of liver fossa index, defined as the product of 3 dimensions of recipient liver fossa, were (25.03 +/- 7.18) x 10(4) mm3 and (127.54 +/- 5.07) x 10(4) mm3, respectively. These two indices clearly indicated the risk of problems due to large graft size, and will help to protect recipients and provide a basis for evaluating graft size in reductions.

Child, Preschool↗

Evolution of genetically correlated traits: tooth size and body size in baboons.

Within a population, only phenotypic variation that is influenced by genes will respond to selection. Genes with pleiotropic effects are known to influence numerous traits, complicating our understanding of their evolution through time. Here we use quantitative genetic analyses to identify and estimate the shared genetic effects between molar size and trunk length in a pedigreed, breeding population of baboons housed at the Southwest National Primate Research Center. While crown area has a genetic correlation with trunk length, specific linear measurements yield different results. We find that variation in molar buccolingual width and trunk length is influenced by overlapping additive genetic effects. In contrast, mesiodistal molar length appears to be genetically independent of body size. This is the first study to demonstrate a significant genetic correlation between tooth size and body size in primates. The evolutionary implications are discussed.

Animals↗

Birth size in relation to age at menarche and adolescent body size: implications for breast cancer risk.

Early age at menarche and tallness are associated with increased risk for breast cancer, and emerging evidence suggests that body size at birth also is positively associated with breast cancer risk in adulthood. We have explored whether this effect of birth size could be mediated by influencing age at menarche or body height during adolescence. Information on age at menarche and adolescent height among 3,343 Norwegian girls 13 to 19 years of age, born at term and whose mothers had no history of gestational disease was individually linked to information on birth weight and length recorded in the national Medical Birth Registry. We related quintiles of birth size, adjusted for length of gestation, to age at menarche and adolescent height and weight, using general linear modeling and Cox regression analyses. In a subsample of the population, we also had information on maternal age at menarche, as well as adult height and body mass index in both parents. We explored whether parental factors confounded the association between perinatal predictors and adolescent outcomes in the daughters. We found that age at menarche tended to occur earlier with decreasing birth weight (p for trend = 0.03), and girls who were thin at birth (i.e., in the lowest quintile of ponderal index) had an earlier age at menarche than other girls (p = 0.02). Weight and length at birth were strongly and positively related to tallness during adolescence (p for trend < 0.001), but ponderal index, indicating obesity at birth, was negatively associated with adolescent height (p for trend = 0.002). Adjustment for parental height, body mass index and maternal age at menarche, in the subsample where this information was available, indicated no substantial confounding by these parental factors. Our results suggest that a positive association between birth size and adult breast cancer is not likely to be mediated by early age at menarche, but possibly by increased body height in adolescence.

Adolescent↗

Relationship between size of parent at cell division and relative size of its progeny in Escherichia coli.

This article examines the empirical basis for the assumption of independence between the relative size (length or surface area) of a newborn cell w and the absolute size of its mother at cell division. Random samples from two strains of Escherichia coli B/r cells in steady-state exponential growth, covering a range of doubling times, were fixed in osmium tetroxide and prepared for electron microscopy by agar filtration. Length and diameter of over 3000 constricted cells were measured from the electron micrographs and cell surface area computed by assuming an idealized geometry of right circular cylinders with hemispherical polar caps. In general, these strains were found to divide into two daughter cells with a precision that is independent of the size of the mother. In addition, both a normal and a symmetrical beta-distribution were shown to fit the observed size distributions of w rather well; theoretical grounds for preferring the latter are discussed.

Cell Division↗

Transthoracic and transesophageal echocardiographic sizing of the aortic annulus to determine prosthesis size.

To assess the accuracy of 2-dimensional echocardiography versus transesophageal echocardiography (TEE) in predicting aortic annulus diameter, and to determine which part of the cardiac cycle should be used for measuring the size of the aortic valve prosthesis in patients undergoing aortic valve replacement, the aortic annulus was measured retrospectively in a blinded fashion in a group of 94 patients who had undergone aortic valve replacement: 66 had preoperative transthoracic echocardiography (TTE), 69 had intraoperative TEE, and 41 had both. Accuracy of measurements was calculated by the mean biases (differences between annular size by echo and actual valve size chosen by intraoperative mechanical sizing of the aortic annulus). TTE was compared with TEE and end-diastolic (ED) measurements with end-systolic (ES) measurements. The mean biases +/- SD were -1.7 +/- 3.4 mm by TTE-ES versus -0.9 +/- 3.5 mm by TEE-ES measurements (p = NS), and +0.03 +/- 3 mm by TTE-ED versus +0.5 +/- 2.8 mm by TEE-ED (p = NS). Examination of the magnitudes of the biases gave the same result. ED measurements were found to have a smaller amount of bias than ES measurements, both by TTE and by TEE: -1.7 +/- 3.4 mm by TTE-ES versus +0.03 +/- 3 mm by TTE-ED (p = 0.0001) and -0.9 +/- 3.5 mm by TEE-ES versus +0.5 +/- 2.8 mm by TEE-ED (p = 0.0001). Examination of the magnitudes of the biases also gave the same result.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗

Comparison of DNA loop size and super-coiled domain size in human cells.

DNA loop size and super-coiled domain size in HeLa cells were investigated by the nucleoid sedimentation technique as well as by analysis of the DNA-nuclear-matrix complex. After X-irradiation, the relaxation of super-coils was not correlated with the release of DNA from the nuclear matrix. The super-coiled domain size was much larger than the average DNA loop size. To explain the results, we propose that unwinding of super-coils in a DNA loop also causes unwinding in adjacent DNA loops in spite of existing attachment sites. Alternatively, the results may be explained by assuming that only very large DNA loops determine the sedimentation behaviour of nucleoids.

Cell Nucleus↗

Size exclusive capillary electrophoresis separation of DNA oligonucleotides in small size linear polyacrylamide polymer solution.

The mobility of analytes in capillary electrophoresis using polymer gels and solutions is usually described as having an inverse relationship with the molecular size (mobility decreases as molecular size increases). The most commonly used models for predicting such mobility are the Ogston model and the Reptation model. However, in this study a new separation phenomenon was observed in which the mobility of DNA oligonucleotides increased with molecular size in a capillary electrophoresis phase (CEP) coated capillary column. The polymer system used was a 11% linear polyacrylamide (Mr = 1500) solution. The log-transformed number of base pairs (log N) of three double stranded oligonucleotides had an inverse linear relationship (r2 > 0.9981) with their migration time in the capillary column. Such a relationship is similar to that observed with size exclusive chromatography.

Acrylic Resins↗

Accidental sizing of patent foramen ovale during atrial septal defect sizing for device.

A 21 year old lady with a 22 mm secundum atrial septal defect with adequate rims, and thin septum at the region of the fossa ovalis, but no additional atrial septal defect by transthoracic and transoesophageal echocardiogram was taken up for ASD sizing with a view to device closure. Initially, the ASD was sized to only 8 mm. However, the distal balloon was not fully opened out, and seemed to be conical with restricted opening. Inadvertent passage of sizing balloon through a patent foramen ovale (PFO) was immediately confirmed by transthoracic echocardiogram. The ASD was then recrossed and sized to 24 mm with normal opening out of the distal balloon. This was confirmed by transthoracic echocardiogram. A 28 mm ASD device was deployed across the ASD under transthoracic echocardiographic guidance with no residual flow.

Adult↗

Surface modification of crosslinked poly(styrene-divinyl benzene) micrometer-sized particles of narrow size distribution by ozonolysis.

Micrometer-sized polystyrene template particles of narrow size distribution were prepared by dispersion polymerization of styrene in 2-methoxyethanol. Uniform micrometer-sized polystyrene/crosslinked poly(styrene-divinyl benzene) composite particles were formed by a single-step swelling process of the template particles with styrene, divinyl benzene and benzoyl peroxide, followed by polymerization at 70 degrees C. Uniform micrometer-sized crosslinked poly(styrene-divinyl benzene) particles of higher surface area were produced by dissolution of the template polystyrene part of the former composite particles with N,N-dimethylformamide. Hydroperoxide conjugated crosslinked poly(styrene-divinyl benzene) particles were produced by ozonolysis of these particles. The effect of ozonolysis conditions, such as exposure time and flow rate of the ozone, on the hydroperoxide conjugation to the crosslinked particles was also studied. Functionalization of the crosslinked poly(styrene-divinyl benzene) particles was performed by graft polymerization of vinylic monomers such as acrylonitrile and chloromethylstyrene on the hydroperoxide conjugated crosslinked particles. This was accomplished by raising the temperature (e.g., 70 degrees C) of deairated acetonitrile dispersions containing the hydroperoxide conjugated particles and the vinylic monomers. The influence of various polymerization parameters on the grafting yield, e.g., monomer concentration, conjugated hydroperoxide concentration, and temperature, was also elucidated.

Journal Article↗

Significance of testicular size measurement in andrology: II. Correlation of testicular size with testicular function.

The testicular sizes of 305 men were measured by a recently developed orchidometer and related to 9 other known parameters of testicular function. Mean testicular size had the strongest correlation with serum follicle-stimulating hormone levels, total sperm count and sperm concentration, while a significant correlation also was noted with sperm motility, percentage of live sperm, sperm morphology (normal and immature forms), and serum luteinizing hormone and testosterone levels. Sperm quantity had stronger correlations with testicular size than did sperm quality, although both were impaired in testes smaller than 14 ml. It is concluded that the size of the testis bears a direct correlation with testicular function and, thus, it can be helpful to assess rapidly andrological status during the initial physical examination.

Adult↗

High Pressure Size Exclusion Chromatography (HPSEC) of humic substances: molecular sizes, analytical parameters, and column performance

High Pressure Size Exclusion chromatography (HPSEC) is increasingly used to evaluate molecular sizes of humic substances from different sources. Asymmetry factors (As), number of theoretical plates (N), coefficient of distribution (k(d)), and column resolution (Rs) were determined for two different HPSEC columns (TSK G3000SW and Biosep S2000) and polysaccharides of known molecular weights were used as standards. Calibration curves were equivalent for both columns whereas analytical parameters revealed that the TSK column was only slightly more efficient in separating polysaccharide standards. Mw and Mn values for humic substances differed according to the molecular weight range of each column but relative standard deviation never exceeded 5% for both columns. Variations between columns were attributed to intrinsic humic properties such as the stability of conformational structures. These results suggested that humic substances in solutions are loosely-bound association of small molecules that may be consistently dispersed by diffusion through size-exclusion pores. HPSEC is confirmed to represent a highly precise method to evaluate the relative molecular-size distribution of dissolved humic substances.

Journal Article↗

Does size and site matter for renal stones up to 30-mm in size in children treated by extracorporeal lithotripsy?

OBJECTIVES: To determine the safety and efficacy of extracorporeal shock wave lithotripsy (ESWL) in the treatment of pediatric nephrolithiasis and to analyze the impact of renal stone size and location on stone clearance. METHODS: This was a retrospective case series of pediatric patients (14 years or younger) undergoing lithotripsy using a Dornier MPL 9000 echo-guided lithotriptor. Patients were identified using an international coding and indexing system (9th edition) and ESWL registry. One hundred five patients were treated from January 1990 to December 2001. Stone clearance was assessed at 1 and 3 months. A stone-free state was defined as no radiologic evidence of stone or fragments 3 mm or less. Treatment failure was analyzed to find any correlation with stone size and site. RESULTS: The overall stone-free rate was 95%. The treatment failed in 5 patients, who subsequently required ancillary procedures. Three patients received one session of ESWL, after which they were lost to treatment and were not analyzed further. Four of the five patients with treatment failure had a double-J stent; the stones were located in the lower pole calix in 2, renal pelvis and lower pole calix in 1, and at the ureteropelvic junction in 2 patients. The mean stone size in the treatment failure group was 15.88 mm compared with 14 mm in the stone-free group. The complication rate was 8%, but only 3 patients required admission. CONCLUSIONS: ESWL is highly effective for pediatric renal stones, with minimal morbidity. Stone clearance is not adversely affected by a stone size up to 30 mm; however, lower pole caliceal stones and stones impacted at the ureteropelvic junction have relatively poorer clearance. Eighty percent of patients who failed to clear their stones had a double-J stent.

Age Factors↗

Reduction in size of the ovulatory follicle reduces subsequent luteal size and pregnancy rate.

We hypothesized that reducing the size of the ovulatory follicle using aspiration and GnRH would reduce the size of the resulting CL, reduce circulating progesterone concentrations, and alter conception rates. Lactating dairy cows (n=52) had synchronized ovulation and AI by treating with GnRH and PGF2alpha as follows: Day -9, GnRH (100 microg); Day -2, PGF2alpha (25 mg); Day 0, GnRH (100 microg); Day 1, AI. Treated cows (aspirated group; n=29) had all follicles > 4 mm in diameter aspirated on Days -5 or -6 in order to start a new follicular wave. Control cows (nonaspirated group: n=23) had no follicle aspiration. The size of follicles and CL were monitored by ultrasonography. The synchronized ovulation rate (ovulation rate to second GnRH injection: 42/52=80.8%) and double ovulation rate of synchronized cows (6/42=14.3%) did not differ (P > 0.05) between groups. Aspiration reduced the size of the ovulatory follicle (P < 0.0001; 11.5 +/- 0.2 vs 14.5 +/- 0.4 mm), and serum estradiol concentrations at second GnRH treatment (P < 0.0002; 2.5 +/- 0.4 vs 5.7 +/- 0.6 pg/mL). The volume of CL was less (P < 0.05) for aspirated than nonaspirated cows on Day 7 (2,862 +/- 228 vs 5,363 +/- 342 mm3) or Day 14 (4,652 +/- 283 vs 6,526 +/- 373 mm3). Similarly, serum progesterone concentrations were less on Day 7 (P < 0.05) and Day 14 (P < 0.10) for aspirated cows. Pregnancy rate per AI for synchronized cows was lower (P < 0.05) for aspirated (3/21=14.3%) than nonaspirated (10/21=47.6%) cows. In conclusion, ovulation of smaller follicles produced lowered fertility possibly because development of smaller CL decreased circulating progesterone concentrations.

Animals↗

Contributions of obesity, gender, hunger, food preference, and body size to bite size, bite speed, and rate of eating.

College students ate two high preference or two low preference doughnuts under high or low hunger conditions. Subjects were led to believe that we were interested in preference ratings made after eating the doughnuts. The number of bites and the total snack time were covertly recorded. Having weighed the doughnuts previously, we calculated the bite size (amount per bite), bite speed (time per bite), and eating rate (amount per second). Eating rate increased as obesity, body size, hunger, and preference increased; men ate at a faster rate than women. Larger bites accounted for the increased rate of the obese, the high preference subjects, and those having a larger body size. The hungry subjects increased their eating rate by taking faster bites. Men ate faster than women by taking both larger but slower bites. Thus eating rate is under multiple control. The data also suggest that the effects of obesity and, in part, gender on these eating responses may be more parsimoniously explained as body size effects. Modification of these within-session eating responses in order to regulate food intake will be successful only when the relationships among these measures are understood.

Adolescent↗