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Glucose-6-phosphate dehydrogenase deficiency and Rh factor.

The incidence of carriers of the Gd(-) gene and the Rh(+) and Rh(-) alleles was studied in 10 342 Bulgarian individuals living in 306 villages in 5 districts at different altitudes above the sea level. The results showed that the presence of the Gd(-) gene is considerably less frequent in Rh(-) than in Rh(+) individuals. In populations with a high frequency of G6PD deficiency the frequency of the Rh(-) allele is low.

Altitude↗