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At least 271 records · Page 15Linked to original sources
PubMed2002

An intrapulmonary chondromatous hamartoma penetrating the visceral pleura: report of a case.

A 65-year-old woman had been followed up for a hamartoma-like mass in the right upper lobe of the lung since 1995. A follow-up CT scan showed an increase in the size of the lesion and a new lesion next to the old mass, which was highly suspected to be lung cancer. A right upper lobectomy was thus performed in May 2000. The hamartoma penetrated the visceral pleura, and adhered to the mediastinal pleura. Such a growing hamartoma with pleural invasion has so far rarely been previously reported.

Adenocarcinoma↗
PubMed2002

Severe hypoglycaemia associated with a giant solitary fibrous tumor of the pleura.

Solitary fibrous tumors (SFT) of the pleura are a rare neoplasm, with benign biological behaviour. Recurrences are rare, and no distant metastases are described in the literature. SFT can secrete hormone-like substances, responsible for paraneoplastic syndromes. The authors describe a case of severe hypoglycaemia due to insulin-like growth factor II (IGF-2)'s secretion by a giant SFT of the pleura. Hypoglycaemia was controlled by the resection of the tumor. Diagnosis and surgical management of these neoplasms are also discussed.

Humans↗
PubMed2003

[Thoracoscopic resection of localized fibrous tumor of the pleura; report of a case and review of the Japanese literature].

A 61-year-old female was admitted with abnormal shadow on chest X-ray. Chest computed tomography (CT) showed a clearly localized flat tumor at the peripheral region of the left lung. We suspected localized fibrous tumor of the pleura (LFTP) and performed video-assisted thoracic surgery (VATS). Under the thoracoscopy, the tumor was connected to the visceral pleura with a short pedicle and completely resected with safety margin. Pathological findings, including immunohistochemical examination, definitely revealed benign LFTP. VATS is a good indication for the diagnosis and treatment of LFTP. This case was reported together with some reviews of the literature.

Female↗
PubMed1992

[How can the extension of lung cancer to the osteo-muscular wall of the diaphragm, the pleura and the apex be assessed radiologically?].

The merits of evaluating the parietal extension of lung cancers is emphasized by the new TNM classification. CT and MRI have added to the conventional radiological techniques. The authors successively analyze the contribution of these techniques to the assessment of extension of lung cancers to the wall, including the costal and phrenic compartments, to the pleura and to the apex. Lung radiographs show obvious lesions, such as extensive costal lysis and major pleural extensions. Computed tomography has better sensitivity and specificity than lung radiographs to establish pleuroparietal involvement; it is best performed in the inclined plane of the ribs and in the high-resolution mode. The presence of costal lysis means parietal involvement, while the integrity of the pleura can be established if the lesion remains at a distance from the wall. The persistence of an extrapleural fatty rim between the tumor and the wall allows ruling out parietal extension. MRI provides accurate details in case of doubtful CT findings for the extension to the costovertebral groove, to the intervertebral foramina, to the peridural space and to the diaphragm. Its major asset is to assess the vertebral, vascular and nervous extension of cancers of the apex pulmonis.

Carcinoma, Non-Small-Cell Lung↗
PubMed1992

[An operated case of malignant localized mesothelioma of the pleura].

An operable case of pedunculated localized mesothelioma of the pleura, a 62-year-old male, came to our clinic with chief complaint of chest X-ray abnormal shadow. On suspicion of pleural tumor, resection was performed. The operative findings revealed that the tumor was arising from visceral pleura of S1 + 2 a segment of left upper lobe, and didn't invade into peripheral tissue. The microscopic findings revealed that the tumor was consist of spindle tumor cells and capillary-like lesions, and had high cellularity and many mitosis. The tumor was diagnosed as localized malignant mesothelioma. Immunohistochemical stainings were performed using six monoclonal antibodies, vimentin, CEA, EMA, keratin (AE1, AE3), Leu-M1. Only vimentin reacted with tumor cells.

Humans↗
PubMed2003

[Liposarcoma of the pleura: an exceptional tumor. A study of two cases].

Primitive intrathoracic liposarcomas are rare tumors mostly located in the mediastinum or in lung parenchyma. Primitive liposarcomas of the pleura are exceptional and show a dramatic clinical course. These tumors are treated by surgery sometimes associated with radiotherapy. We report 2 cases of primitive liposarcoma of the pleura occurring in 2 women of 19 and 62 years of age. Histological examination showed in both cases a low-grade myxoid liposarcoma. In one case, ultrastructural study confirmed the diagnosis.

Adult↗
PubMed2004

Natural history of multifocal solitary fibrous tumors of the pleura: a 25-year follow-up report.

We report this case with "multifocal solitary fibrous tumors of the pleura," which recurred at different sites in the left pleura at different time intervals over a span of 25 years, finally exhibiting features of malignant transformation. This patient was first seen in 1978, when she was 58 years of age, for episodic attacks of hypoglycemia and a mass occupying the entire left hemithorax. The operative findings and histologic appearance were that of a solitary fibrous tumor.

Female↗
PubMed1992

[Diseases of the pleura. Materials used and study technics].

Pleural diseases frequently pose problems to the pulmonary physician. The clinical and radiological approaches are often insufficient and it is necessary to resort to techniques which enable a precise morphological diagnosis of the pleural lesion. Starting with a needle puncture and biopsy, the medical investigation of the pleura has been enriched by thoracoscopy which enables visualisation of not only the parietal and visceral pleura and the lung but also the mediastinum and the pericardium. Using this technique the diagnostic yield and the harmless nature of the technique are of the first importance. After recording traditional techniques of investigation of lung disease (puncture, needle biopsy) the equipment, the technique, the indications and the risks and the diagnostic results from thoracoscopy are discussed.

Biopsy, Needle↗
PubMed2006

[Prediction of the course of acute purulent diseases of the lung and pleura].

The paper presents the data of examination of 62 patients with acute purulent diseases of the lung and pleura (abscess, empyema, pyopneumothorax). The persistent and virulent characteristics of causative agents isolated just from a suppuration focus during its puncture are described. There was an association of the high level of antilysozyme, anticomplementary, and hemolytic activities of bacterial pathogens with the severe course of a disease. On this basis, a mathematical model that can predict the course of acute purulent diseases of the lung and pleura with an accuracy of as high as 95% has been constructed.

Acute Disease↗
PubMedDate not supplied

[Pleura's solitary fibrous tumor. Clinical pathology analysis of 17 cases].

INTRODUCTION: Solitary fibrous tumor of the pleura (SFTP) is a rare neoplasm that usually originates from the visceral pleura, but it can occur in a wide range of tissues. Approximately 12% of pleural cases are malignant tumors and surgical excision usually become curative. The objective of this study is to present 17 new cases of SFTP and analyze the morphological characteristics that help to identify tumors with a malignant behavior. MATERIAL AND METHODS: We did a retrospective review of the patients who had primary pleural tumors from January 1995 to August 2005. RESULTS: Among a total of 94 primary pleural tumors, 17 patients were enrolled in this study, 8 men and 9 women, with a mean age of 63 years. Thirteen cases (76%) were benign and four cases (23%) were malignant. Local recurrences occurred in three cases. There were no metastases found. Recurrences occurred only in malignancy tumors. All malignant tumors were high cellularity and had hemiangiopericitic pattern, more than 4 mitoses per 10 high power fields, and moderate to marked polymorphism. CONCLUSIONS: SFTP shows a benign biologic outcome in most of the cases. There are some histological characteristics that led to distinguish between benign and malign neoplasm.

Adult↗
PubMed1990

[Indications for surgery and results of 207 thoracotomies in children with diseases of the lung, pleura and mediastinum].

Between 1968 and 1988, 207 children with congenital, inflammatory, and neoplastic diseases of the lung, pleura, and mediastinum underwent thoracotomy. In 34 patients indication for operation was a therapy-resistent recurrent spontaneous pneumothorax, in 25 benign and malignant mediastinal tumors, in 26 pulmonary metastases of extrathoracic primary tumors, in 42 bronchiectasis and post-pneumonic empyema with callosity, in 21 bronchogenic and enterogenous cysts. 22 children had benign tumors of the trachea, bronchi, and lung, 5 malignant tumors of the lung and chest wall. In a smaller number of children congenital defects, parasitic cysts, and aspergillomas as well as foreign bodies, were present. The surgical procedure included anatomical and atypical resections, bronchoplastic interventions, exstirpation of tumors and cysts, decortications and partial resections of the parietal pleura. There was no perioperative mortality.

Child↗
PubMed1991

[Helium-neon laser irradiation in combined treatment of children with suppurative diseases of the lungs and pleura].

The article discusses the results of treatment of acute ischemia of the pleura in 60 children with the use of intracavitary laser therapy. The empyema cavity was irradiated through a quartz flexible monocrystal light guide. The authors studied the effect of helium-neon laser beam on the empyema microflora, the condition of immunity, and the specific features of the clinical course of acute empyema of the pleura. Treatment by helium-neon laser radiation promotes rapid closure of bronchopleural fistulas, reduces the period of treatment, causes an immunocorrection effect, and does not exert a bactericidal effect on the flora.

Adolescent↗
PubMed1990

[localized fibrous tumors of the pleura].

The localized fibrous tumour of the pleura, also named localized fibrous mesothelioma or fibroma of the pleura, is a very rare tumour with a benign behaviour. Its origin, clinical behaviour and prognosis are very different from malign mesothelioma. In a 33-year period 22 patients with this diagnosis were surgically treated. The prognosis was excellent. In this article the clinical and radiological signs, as well as the diagnosis and therapy are discussed.

Adult↗
PubMed1986

The diagnostic distinction between malignant mesothelioma of the pleura and adenocarcinoma of the lung as defined by a monoclonal antibody (B72.3).

The correct distinction between malignant mesothelioma of the pleura and adenocarcinoma of the lung has become increasingly complex, with a variety of histochemical, immunohistochemical, and ultrastructural studies to be performed on biopsy material. The reliability of immunohistochemical studies has been hampered by the use of polyclonal antisera to "carcinoembryonic antigen (CEA)" and keratin. Hybridoma technology now offers monoclonal antibodies (MAbs) in unlimited quantity and standardized quality to selective ranges of specific antigenic determinants. MAb B72.3, generated against a membrane-enriched fraction of human metastatic breast carcinoma, was used to distinguish malignant mesothelioma of the pleura from adenocarcinoma of the lung in tissue sections and was compared in terms of diagnostic utility with polyclonal anti-keratin and anti-CEA to make the same distinction. Reactivity with MAb B72.3 in at least 10% of tumor cells or more was noted in 19 of 22 adenocarcinomas of the lung (P greater than 0.0001), whereas none of the 20 cases of malignant mesothelioma demonstrated comparable reactivity. Furthermore, MAb B72.3 showed no reactivity with benign mesothelial proliferations. MAb B72.3 thus appears to be an appropriate diagnostic adjunct capable of discriminating between these malignancies.

Adenocarcinoma↗
PubMed1987

[Localized fibrous mesothelioma of the pleura. Morphological studies of 7 cases].

Localized tumors of pleura should clearly be separated from diffuse pleural mesotheliomas due to clinical and pathological peculiarities. But there is some dispute on their proper interpretation and hence disagreement about their correct designation. Some call them "fibrous tumors (fibromas)" of pleura and appreciate by this term the fibroplastic potency of tumor cells and the lacking relation to overlying mesothelial surface cells, others prefer the name "fibrous mesothelioma" and allude to an at least abortive mesothelial differentiation within the tumor tissue. Examining 7 own tumor cases by means of light microscopic, topo- and immunohistochemical as well as electron microscopic methods the investigations were aimed at analysing the morphological structure of these tumors and subjecting it to a critical reappraisal with regard to a suited designation. Histologically, a marked variability of histological structure and texture was found, there were regions with similarities to fibromas, fibrous histiocytomas, hemangiopericytomas and nerve sheath tumors as well as blastema-like areas. Occasionally a vasoformative activity could be seen. In three tumors a few epithelioid cell complexes were visible, but neither keratin intermediate filaments nor UEA-I reactivity was to be demonstrated by immunohistochemistry. Antibodies against factor VIII associated antigen only marked endothelial cells of vascular structures. By the electron microscopic examination of 1 case abortive mesothelial differentiations were visualized (some lumen-like space formations, stub-like cellular projections of the cavity facing side, primitive intercellular junctions and fragmented basal lamina-like material). The findings inclusive the immunohistochemical results are discussed and jointly taken for sustaining the interpretation of these tumors as mesotheliomas and for militating against the classification as simple pleural fibromas or fibrous pleural tumors, respectively.

Adult↗
PubMed1986

[Low-frequency ultrasound in the treatment of acute and chronic suppurative diseases of the lungs and pleura in children].

The maximum exposure and regimens of action of the low frequency ultrasound on the lung and pleura tissue were established in experimental studies. The ultrasound energy was used in the clinic for the complex treatment of 139 patients with acute purulent diseases of the lungs and pleura and in 76 children with chronic bronchopulmonary pathology. High therapeutic effects were achieved which suggests the further application of the method to be fairly promising in children surgery.

Adolescent↗
PubMed1977

[Functional morphology of the pleura (author's transl)].

Peculiarities of topography, structure and injuries are responsible for the pathomorphological behaviour of the pleura. Its characteristical macro- and microscopic alterations are correlated with the typical cytological findings of effusions. Additionally to the pleural reactions in acute inflammation, the postpleuritic functional disturbances of pleura and lung are reported.

Acute Disease↗