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PubMed1991

[Diagnosis and etiopathogenesis of retinitis in patients with multiple sclerosis].

Presented are: the incidence, symptomatology and diagnostics together with electroretinography of retinal periphlebitis as well as retinitis and maculopathy in patients with multiple sclerosis. Particular attention is called to the histopathology of the retina in this disease. The etiopathology of retinitis and maculopathy in multiple sclerosis is still unknown. Four etiopathological hypotheses are shortly discussed.

Electroretinography↗

PubMedDate not supplied

[Ophthalmologic manifestations of acquired immunodeficiency syndrome (AIDS) in central Africa].

In central Africa, the authors have performed an ophthalmological examination of 77 adult patients (18-55 years) with AIDS: 33.7% had ocular abnormalities. Frequent manifestations included cotton-wool patches and retinal hemorrhages, while lacrymal hyposecretion, palpebral and conjunctival kaposi sarcoma, ocular palsy, ptosis, herpes zoster, papillar oedema, cytomegalovirus retinitis and periphlebitis were less frequent. The authors underline the necessity to perform an ocular examination for each patient with AIDS.

Acquired Immunodeficiency Syndrome↗

PubMed1987

[Eales' syndrome. Clinical aspects, therapeutic indications and course of 29 cases].

Biomicroscopic examination of these cases showed vitreous hemorrhages in 18 eyes, retinal hemorrhages in 18 eyes, periphlebitis in 16 eyes, equatorial neovascularization in 16 eyes, macular involvement in 9 eyes (macular-cystoïd edema or macular pucker), prepapillary neovascularization in 15 eyes. Fluorescein retinal angiography was performed when it was possible. Follow up of these eyes upon and over six months, treated by corticotherapy for 11 eyes, retinal photocoagulation for 32 eyes, and vitrectomy for 9 eyes, led to separate non evolutive entities (30 eyes) from evolutive entities (6 eyes). Complications happened in 15 eyes, 4 eyes ended with neovascular glaucoma. 40 eyes maintained ambulatory or calibrated acuity.

Adolescent↗

PubMed1988

Sarcoidosis and peripheral neovascularization.

Twenty-eight patients with sarcoidosis were examined. Four of the patients had a history of uveitis. Retinal periphlebitis was noted in one case, and peripheral retinal neovascularization was found in two non-sickle cell black patients. Vitreous hemorrhage developed in one of the patients with neovascularization, prior to laser treatment and this patient eventually required vitreous surgery. The other patient was treated with prophylactic laser. Peripheral retinal neovascularization may be a noteworthy finding that will be found in larger numbers with attention to the retinal periphery in cases of sarcoidosis.

Adult↗

PubMed1989

[Sarcoidosis with ocular involvement].

A 28-year-old Chinese woman having sarcoidosis with ocular involvement was reported. She demonstrated bilateral hilar lymphadenopathy in a chest X-ray which was taken for a cough. Transbronchial lung biopsy revealed noncaseating epithelioid granulomas. Blurred vision occurred 8 months later when conjunctival follicle-like masses, granulomatous keratic precipitates, iridocyclitis, "snow-ball" vitreous opacity, and retinal periphlebitis developed in both eyes. Biopsy of the conjunctival follicle-like masses revealed noncaseating granulomas composed of epithelioid cells and multinuclear giant cells, typical of sarcoidosis. The ocular lesions waned under topical steroid treatment and vision improved. This is the only case with an ocular involvement among the 10 cases of sarcoidosis seen during the past 20 years at the Taipei Veterans General Hospital.

Adult↗

PubMed1987

[Preliminary results of a randomized trial comparing the efficacy of standard heparin with that of fragmine, a low molecular weight heparin, in the prevention of postoperative thrombosis in cancer surgery].

Low molecular weight heparins have stimulated much interest because of their supposedly more selective action on Xa factor. A randomized study in 50 patients compared efficacy of low doses of a standard heparin, calciparin (5,000 IU/8 h) with that of a low molecular weight heparin, fragmine (Kabi 2165) (5,000 anti-Xa U/24 h), in the prophylaxis of postoperative thrombosis after oncologic surgery. Three of 25 patients receiving calciparin developed pulmonary embolism, as against one of 25 treated with fragmine who developed a periphlebitis. Hemorrhagic complications were comparable in the two groups. Anti-Xa activity was significantly higher in the fragmine group, whereas platelet counts, cephalin times with activator and anti-IIa activity were similar. These findings indicate equal efficacy of fragmine and calciparin in the prophylaxis of post-oncology surgery venous thrombosis.

Adult↗

PubMed1988

[Venous thrombosis in Behçet's disease].

Venous lesions in Behçet's disease (BD) were defined by Adamantiades and represent one of the most suggestive signs of the disease. They are occasionally the first sign of the disease and are frequently the basis for the diagnosis in a case of recurrent thrombosis in a young subject, the preferential context of BD. Involvement of superficial vessels is virtually constant. Venous vasculitis is responsible for non-specific hypersensitivity and erythema nodosa, which constitute some of the major diagnostic criteria. Ocular periphlebitis is one of the elements responsible for posterior uveitis. The originality of the venous involvement is due to the involvement of deep territories. Any vein may be affected, but the remarkable features are the size of the thrombosed vessels: superior and inferior vena cava, iliofemoral veins and the unusual site of the involvement: supra-hepatic veins, cerebral vessels, etc. Inferior vena cava thrombosis may be associated with aneurysms of the pulmonary arteries in the context of Hughes-Stovin syndrome. Cerebral phlebitis, which can now be identified more easily by means of digital angiography, is responsible for a typical picture: headaches, bilateral papilloedema and raised CSF pressure. The classical pictures of optic chiasmatic arachnoiditis and so-called benign intracranial hypertension actually correspond to unrecognised phlebitis. They may also be associated with other neurological lesions. In one half of cases, phlebitis cutaneous manifestations. However, they may precede the diagnostic signs or may occur very late in the course of the disease. They are recurrent and affect a number of different territories.(ABSTRACT TRUNCATED AT 250 WORDS)

Anti-Inflammatory Agents↗

PubMed1987

Pathogenesis of Sarcocystis falcatula in the budgerigar. II. Pulmonary pathology.

Sarcocystis falcatula is a protozoan parasite which obligatorily alternates its definitive host, the opossum (Didelphis virginiana), and a uniquely wide range of avian intermediate hosts. The disease produced by this coccidian parasite in intermediate hosts was studied in the budgerigar bird (Melopsittacus undulatus). Early schizogony occurs in pulmonary endothelial cells, resulting in endothelial cell hypertrophy, capillary obstruction preceding endothelial lysis, acute endophlebitis, and chronic periphlebitis. These impede outflow of the pulmonary vascular system resulting in interstitial, subpneumocytic, and then air-space edema. The edema is associated with retraction and degeneration of squamous pneumocytic processes, loss of the myelinoid "surfactant" covering over the pneumocytes, and atelectasis of the respiratory labyrinth. Epithelial repair is effected by migration of granular pneumocytes (normally confined to the parabronchi and their atria) down the infundibula and into the respiratory labyrinth. This pattern of injury and repair is comparable to diffuse alveolar damage (acute interstitital pneumonitis) of mammals despite the markedly different structure of the avian lung. The implications of this peculiar tissue tropism are discussed.

Animals↗

PubMed1986

Retinal arteriolar occlusion in multiple sclerosis.

A 25-year-old white man presented with acute multiple sclerosis manifested by right blindness, difficulty urinating, and paresthesias and weakness of both legs. Retinal examination revealed a distal occlusion of the descending branch of the superior temporal arteriole leading to an area of retinal ischemia of the right eye. The optic disc was edematous, and there were focal areas of periphlebitis. All retinal signs resolved in three weeks, and the only abnormality that persisted was a pale right optic disc. The finding of small arteriolar disease is unusual and may represent another possible pathogenetic mechanism in multiple sclerosis.

Adult↗

PubMed1979

[Vascular anastomoses at the posterior pole of the eye (author's transl)].

Anastomoses between vessels of the fundus may occur as congenital malformations or secondary to vascular diseases affecting the eye. Congenital anastomoses can be of the racemose hemangioma type, with severe malformation of the retinal vessels, ocular complications, and neurologic manifestations, or as simple A-V shunts with visual impairment but limited tendency to show other ocular or neurologic involvement. These anastomoses must be distinguished from other vascular malformations like telangiectasis (Leber, Coats) or the angiomatous lesions of von Hippel's disease. Secondary anastomoses may be confined to the retinal vessels or involve chorioretinal connections. Retinal anastomoses occur in vascular disorders like retinal vein occlusions, diabetes, periphlebitis and hemoglobinopathies. They are often amenable to treatment by light coagulation. Chorioretinal anastomoses occur whenever Bruch's membrane is destroyed by traumatic, inflammatory, degenerative or physical (light coagulation) influences. Light coagulation may be the appropriate treatment, although complications are not rare.

Adolescent↗

PubMed1979

Eales' disease: a case of rapid progression.

A case of bilateral vitreous hemorrhage is presented in a young black man. Work-up showed the patient to have Hb AA with a markedly positive PPD and a negative chest roentgenogram. A diagnosis of periphlebitis retinae or so-called Eales' disease was made. This case was remarkable in its speed of progression and the severity of the disease process. This case calls attention to the importance of rapid diagnosis and evaluation for possible treatment.

Adult↗

PubMed1978

[Eye tuberculosis].

At present the eye tuberculosis still occurs only in its reactive form. But also these pathological processes may quite considerably disturb the vision. In the first place are chorioiditis (uveitis posterior), iritis and iridocyclitis (uveitis anterior), uveitis totalis and periphlebitis retinae are by far less frequent. Number and severity of the pathological processes considerably decreased during the last years, above all also the new diseases. Relapses are still increasedly observed. The problems of diagnostics and the necessary therapeutic measures are described.

Adult↗

PubMed1983

[Contribution to the recognition of Mondor's phlebitis].

The AA. have carried out a complete review of the world literature on Mondor phlebitis of the last 50 years (214 cases) pointing out the clinic and epidemiologic characteristics and those of a possible aetiogenesis. 11 personal cases, detailed characteristics of which are given, have been presented. The female sex is the most affected (63,3%) and the most frequent aetiopatogenetic factors are: accidental or surgical traumas (35,7%), muscular stresses (6,3%, centres of infection (4,3%, concomitant mammary pathology (2,4%). The most common symptom is pain (51%) with or without tension sensation (28,9%). The histologic aspect relevant to the biopsy, shows the characteristics of thrombophlebitis non specific, almost always without periphlebitis. The cases presented by the AA. are characterized by the high incidence of relapses (45,4% against 5% of the total cases in the world) as well as by the occasional positivity of the specific serum-agglutination for the Rickettsia Q18 (2 cases out of 11) and the reduction of some immunologic tests (1 cases out of 11). This latter data are leading to two aetiopatogenetic hypothesis: the infective and immunitary one.

Breast↗

PubMed1980

[Clinical aspects and course of Adamantiades-Behçet disease in Tunisia: a report on 41 cases (author's transl)].

The clinical aspects and course of Behçet's disease in Tunisia are discussed. This affection is of frequent occurrence and should be systematically searched for in all patients with uveitis. Ocular manifestations are observed in 95 p. cent of cases. These are characterized by their polymorphic nature and the diagnosis should be suspected in cases with uveitis, periphlebitis, venous thrombosis, vitreous hemorrhage, congestive glaucoma, or macular edema. The characteristic signs of the disease appear over an extended period of time, making definite diagnosis difficult, but early, vigorous therapy is necessary to ensure a favorable prognosis.

Adult↗

PubMed1980

Presumed ocular tuberculosis.

Tuberculosis, once thought to be the most common cause of uveitis, is now thought to be a relatively rare cause of ocular disease. This is because of a decreased incidence of tuberculosis as well as a lessened emphasis on its diagnosis. The majority of cases of posterior uveitis and retinitis today are toxoplasmosis, histoplasmosis and other viral causes along with undetermined etiology. Following is a case report of a retinitis and periphlebitis of presumed tuberculous etiology because of the systemic involvement of the patient.

Diagnosis, Differential↗

PubMedDate not supplied

[Use of a crochet hook for stripping incompetent, perforating veins as an adjunct to sclerosant therapy].

If during the course of sclerosant treatment an incompetent perforating vein situated along the course of a varicose trunk is not obliterated, or alternatively recanalises just after a temporary obliteration, the therapeutic phlebitis has an irregular appearance, being hard and solid in its proximal course, weak or even absent at the point of leakage, and soft and inflamed below it. At this level there often develops a periphlebitis of long duration, followed by recurrence of the varicosity. In such cases the author attacks the incompetent perforator using a hook. Analysis of 68 ruptures carried out in this way (15 on perforating veins on the medial side and 37 on "Cockett 3") shows that this small operation is quite harmless and rapidly improves the quality of the sclerosis.

Humans↗

PubMed1995

[Outcome of Behçet disease in ophthalmologic practice in Morocco].

We treated 123 patients with Behçet's disease during a period of 10 years (1984-1993). The ocular lesions include uveal lesions especially the posterior lesions and vascular retinal. Uveitis was total in 72% of cases. Periphlebitis occurred in 51% of cases, vein occlusion in 10% of cases, macular oedema in 16% and papillary oedema in 10%. Clinical course and prognosis were studied. The functional prognosis is poor as such lesions may lead to blindness, particularly due to papillary oedema maculopathy. The treatment used is based on immunosuppressive and corticoid steroid drugs.

Adult↗

PubMed1995

[Outcome of Behçet disease in ophthalmological milieu in Morocco].

Adult↗