Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Neoplasm recurrence”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 271 records · Page 15Linked to original sources
PubMed1975

[Experience with radical surgery for tumor persistence or recurrence after primary irradiation of cervix neoplasms].

At first the general problems of operations in the x-ray treated tissue are discussed. After that 11 cases of patients, who were x-rayed, were demonstrated. With these patients we carried out a radical operation, because the cancer of cervicis was insufficiently affected by a primary radiological therapy. The bad turn of disease could not be stopped at 6 cases. The women patients got either uretero-vaginal-fistulae (2) or recto-vaginal-fistulae (2) or combined vesico-recto-vaginal-fistulae (1) and in less than one year they died of recidiv of cancer. Two women patients are still tended on account of their vesico-recto-vaginal fistulae. Only three women had been cured satisfactorily and they are till now free of recidivs for 4 to 7 years.

Adult↗
PubMed1985

Radiofrequency hyperthermia as adjuvant therapy following surgical resection of an experimental malignant neoplasm.

Local recurrence after radical surgery is a major problem with many primary solid cancers. The use of radiofrequency hyperthermia (RFHT) as adjuvant therapy to surgery was explored in the Fischer bladder carcinoma (FBCa)/F344 rat tumor system. After subcutaneous innoculation of 34 rats with 10(6) FBCa cells in suspension, RFHT was administered to 17 animals on days 1, 5, 8, and 12. The development of palpable tumors was delayed but not prevented, and tumor growth was retarded in RFHT-treated animals. In another experiment 40 rats were innoculated by subcutaneous trocar injection with a 1 mm3 piece of FBCa. After tumor excision on day 17, adjuvant therapy (untreated control, mitomycin C, RFHT, or RFHT plus mitomycin C) was started on day 20 (10 rats/treatment). The 20 RFHT-treated rats had only 1 incisional recurrence as compared to 9 recurrences in sham-heated rats (P less than 0.005). The authors conclude that RFHT has considerable value as adjuvant therapy to surgery in these tumors. Additional studies of RFHT as adjuvant treatment after surgical excision of tumors are planned.

Animals↗
PubMed1993

[Surgical treatment of local recurrence of malignant lung neoplasms].

Forty-seven reoperations were performed on 46 patients for local recurrence of carcinoma and other malignant tumors of the lung after surgical treatment. In two thirds of cases the local recurrence was a consequence of various errors in therapeutic tactics and surgical techniques made during the operation for the primary tumor. The malignant lung tumor recurred in periods of 4 weeks to 20 years after the operation, but mostly (in 74.5% of patients) in the first 5 years. The authors believe that the criteria of a local recurrence are the same morphological structure as of the primary tumor and localization of the second tumor in the stump of the resected bronchus or in the zone of the previous operation. In 17.0% of cases the recurrent tumor was less differentiated than the primary tumor, and in 34.0% it metastasized to the regional lymph nodes. Pneumonectomy-type removal of the remaining parts of the pulmonary tissue was the operation of choice in local recurrence of lung carcinoma. Organ preserving operations were performed only in local recurrence of less malignant tumors. Five-year survival after repeated operations in local recurrence of malignant lung tumors was 42.6% and depended on the morphological structure of the recurrent tumor.

Adolescent↗
PubMed1994

Changes in human papillomavirus typing of recurrent respiratory papillomatosis progressing to malignant neoplasm.

A patient with recurrent respiratory papillomatosis progressed spontaneously to carcinoma resulting in death. Serial biopsy specimens obtained during a 9-year course of this patient's disease were tested via polymerase-chain reaction and Southern hybridization to detect the human papillomavirus (HPV) types present during the patient's course of disease. Early biopsy specimens were positive for HPV types 6 and 11. As atypia progressed to carcinoma, HPV types 6 and 11 remained present, but the signal decreased and HPV 16 became increasingly positive. The significance of these findings will be discussed.

Carcinoma, Squamous Cell↗