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PubMed1994

Retrieval mechanisms in the development of instance and superordinate naming of pictures.

Children's use of superordinate names lags behind their use of instance names, and production lags behind comprehension. The hypothesis that both of these developmental delays reflect underlying retrieval difficulties predicts an interaction between name generality (instance vs. superordinate) and task (comprehension vs. production). Specifically, production of superordinate names should be more difficult for children than the separate name generality and task effects would predict. To examine this hypothesis, 32 junior kindergarten and 32 Grade 1 children in Experiment 1 performed an instance and superordinate name comprehension task for 96 single-exemplar pictures from 12 categories, and 32 junior kindergarten and 32 Grade 1 children in Experiment 2 produced instance or superordinate names for the same pictures. As predicted, the combination of superordinate names and language production was particularly difficult, especially for junior kindergarten children. High rates of instance name intrusions and other findings suggest that superordinate name production may be interfered with by more readily available instance names. Weak inhibition of competing instance names and other mechanistic explanations for the effects are considered.

Child↗

PubMed2002

How brand names are special: brands, words, and hemispheres.

Previous research has consistently shown differences between the processing of proper names and of common nouns, leading to the belief that proper names possess a special neuropsychological status. We investigate the category of brand names and suggest that brand names also have a special neuropsychological status, but one which is different from proper names. The findings suggest that the hemispheric lexical status of the brand names is mixed--they behave like words in some respects and like nonwords in others. Our study used familiar upper case brand names, common nouns, and two different types of nonwords ("weird" and "normal") differing in length, as stimuli in a lateralized lexical decision task (LDT). Common nouns, brand names, weird nonwords, and normal nonwords were recognized in that decreasing order of speed and accuracy. A right visual field (RVF) advantage was found for all four lexical types. Interestingly, brand names, similar to nonwords, were found to be less lateralized than common nouns, consistent with theories of category-specific lexical processing. Further, brand names were the only type of lexical items to show a capitalization effect: brand names were recognized faster when they were presented in upper case than in lower case. In addition, while string length affected the recognition of common nouns only in the left visual field (LVF) and the recognition of nonwords only in the RVF, brand names behaved like common nouns in exhibiting length effects only in the LVF.

Adult↗

PubMed2000

L-NAME causes antinociception by stimulation of the arginine-NO-cGMP pathway.

NG-nitro-L-arginine methyl ester (L-NAME) has been used extensively as a paradigmatic inhibitor of NO synthase and has been shown to cause antinociception in several experimental models. We describe here how L-NAME produced a dose-dependent antinociceptive effect when injected intraperitoneally in the mouse after acetic acid induced writhings, or intraplantarly in the rat paw pressure hyperalgesia induced by carrageenin or prostaglandin E2. In contrast another NO synthase inhibitor, NG-monomethyl-L-arginine (L-NMMA), had no significant effect per se but inhibited L-NAME systemic induced antinociception in mice and local induced antinociception in the rat paw hyperalgesia test. D-NAME had no antinociceptive effect upon carrageenin-induced hyperalgesia. Pretreatment of the paws with two inhibitors of guanylate cyclase, methylene blue (MB) and 1H-:[1,2,4]-oxadiazolo-:[4,3-a] quinoxalin-1-one (ODQ) abolished the antinociceptive effect of L-NAME. L-Arginine and the cGMP phosphodiesterase inhibitor, MY 5445 significantly enhanced the L-NAME antinociceptive effect. The central antinociceptive effect of L-NAME was blocked by co-administration of L-NMMA, ODQ and MB. The present series of experiments shows that L-NAME, but not L-NMMA, has an antinociceptive effect. It can be suggested that L-NAME causes the antinociceptive effect by stimulation of the arginine/ NO/ cGMP pathway, since the antinociceptive effect of L-NAME can be antagonized by L-NMMA and abolished by the guanylate cyclase inhibitors (MB and ODQ). In addition, the NO synthase substrate, L-arginine and the cGMP phosphodiesterase inhibitor, MY5445 were seen to potentiate the effects of L-NAME. Thus, L-NAME used alone, has limitations as a specific inhibitor of the arginine-NO-cGMP pathway and may therefore be a poor pharmacological tool for use in characterising participation in pathophysiological processes.

Analgesics↗

PubMed1996

The neural regions sustaining object recognition and naming.

This positron emission tomography study dissociates the neural correlates of object recognition and naming. Stimuli comprised coloured outline drawings of objects and coloured nonsense shapes. Subjects either viewed or explicitly named objects, similarly they viewed or named the colour of the shapes. Activations common to object and colour naming were identified by contrasting the explicit naming conditions (objects and colours) with the control (viewing) conditions. Activations associated with object recognition were identified by contrasting both object conditions (naming and viewing) with both shape conditions and activations specific to object or colour naming were identified by contrasting object naming (relative to object viewing) with colour naming (relative to shape viewing). The results associate: (i) object recognition with left middle occipital and bilateral anterior temporal cortices; (ii) modality independent naming with left posterior basal temporal lobe and the left prefrontal cortex; (iii) areas specific to object naming with left temporal extrasylvian regions, left anterior insula and right cerebellum; and (iv) areas specific to colour naming with left posterior lingual and fusiform gyri and midline cerebellum. These results are discussed in relation to previous neuroimaging and neuropsychological findings.

Adult↗

PubMedDate not supplied

A clinical rationale for assessing rapid automatized naming in children with language disorders.

Three continuous rapid naming tasks (Semel, Wiig, & Secord, 1995) were administered to 2,450 American, English-speaking, academically achieving individuals with typical language development and intellectual ability (ages 6 to 21 years) and 136 individuals with primary language disorders (LD; ages 6, 7, 9, 11, 12, 15-16). Naming time in seconds differed significantly (p < .01) between the groups for color naming (Task 1) at age 12, shape naming (Task 2) at age 6, and color-shape naming (Task 3) at ages 6, 7, 9, and 12. Naming accuracy did not differ significantly (p > .01) between groups at the majority of the age levels compared. In the normative group, naming speed increased with age in a monotonic progression. The developmental trajectory in the LD group was essentially parallel, but elevated. The percentages of individuals who failed the naming-time criteria for Task 3 (color-shape naming) differed significantly in the two groups at all ages compared (p < .05). These findings indicate that the requirements for two-dimensional, continuous naming (Task 3 color-shape naming) resulted in reduced naming speed (longer total times) and interference with fluency in language production in about half of the clinical sample.

Adolescent↗

PubMed2006

Semantic priming over unrelated trials: evidence for different effects in word and picture naming.

Two naming experiments are reported that replicated previous findings of semantic interference as a result of naming related word or picture primes three trials before picture targets. We also examined whether semantic interference occurred when the materials were reversed and picture or word primes were named before word targets. The interest in semantic interference during word naming followed a suggestion made by Humphreys, Lloyd-Jones, and Fias (1995) that word naming, like picture naming, may be reliant on a semantic route to name retrieval when the two stimuli are mixed. In contrast to their findings, we found no evidence for semantic interference during target word naming; in fact, we found facilitation from related picture primes. No priming was found for the related word prime and word target condition. The data allow us to rule out the possibility that word naming is reliant on a semantic route when mixed with pictures in this priming paradigm and to conclude that there is no clear evidence of semantic activation during word naming. We also conclude, in line with other research, that word naming and picture naming involve different processes.

Adolescent↗

PubMed1989

Referential processing: reciprocity and correlates of naming and imaging.

To shed light on the referential processes that underlie mental translation between representations of objects and words, we studied the reciprocity and determinants of naming and imaging reaction times (RT). Ninety-six subjects pressed a key when they had covertly named 248 pictures or imaged to their names. Mean naming and imagery RTs for each item were correlated with one another, and with properties of names, images, and their interconnections suggested by prior research and dual coding theory. Imagery RTs correlated .56 (df = 246) with manual naming RTs and .58 with voicekey naming RTs from prior studies. A factor analysis of the RTs and of 31 item characteristics revealed 7 dimensions. Imagery and naming RTs loaded on a common referential factor that included variables related to both directions of processing (e.g., missing names and missing images). Naming RTs also loaded on a nonverbal-to-verbal factor that included such variables as number of different names, whereas imagery RTs loaded on a verbal-to-nonverbal factor that included such variables as rated consistency of imagery. The other factors were verbal familiarity, verbal complexity, nonverbal familiarity, and nonverbal complexity. The findings confirm the reciprocity of imaging and naming, and their relation to constructs associated with distinct phases of referential processing.

Adult↗

PubMed2005

Potential deterrent effect of name-based HIV infection surveillance.

To meet federal recommendations to collect case reports of HIV infection, California has adopted a non-name code system to conduct HIV surveillance. The objective of this study was to evaluate among HIV test takers the acceptability and preferences for the 3 major types of HIV infection reporting-name, name-to-code, and non-name code. Interviewer-administered exit surveys with spoken scripts and matching printed materials clearly outlining the 3 HIV reporting options were conducted among HIV test takers immediately following appointments for pretest HIV counseling and blood collection. The study enrolled 208 HIV test takers at 14 publicly funded HIV testing sites in 4 California counties (Los Angeles, Riverside, Fresno, and Santa Clara). Overall with respect to which would be the most acceptable system, 67% reported non-name code, 19% reported name-to-code, and 12% reported name-based HIV reporting (P < 0.0001). A second sample of 226 exit surveys taken 1 year following implementation of California's non-name code HIV infection reporting system continued to show a significant preference for non-name code HIV infection reporting. Significant independent predictors of a preference for coded HIV reporting in both the pre- and postimplementation period were men who have sex with men (odds ratio [OR] = 5.7, 95% CI: 1.2-26 in the preperiod) and having just taken an anonymous HIV test (OR = 3.6, 95% CI: 1.4-9.3, P = 0.009 preperiod). Were the state to adopt name-based HIV reporting, significantly fewer individuals report being likely in the next 12 months to have a confidential HIV test than report being likely to have an anonymous HIV test (51% likely confidential vs. 76% likely anonymous, P < 0.0001). This analysis documents strong support, among HIV test takers in California, for a non-name coded HIV reporting system and indicates a high probability of a shift away from confidential testing toward anonymous testing under a scenario of name-based reporting. This shift is of concern as confidential HIV testing is the basis of US HIV surveillance systems.

Adult↗

PubMed2006

List of new names and new combinations previously effectively, but not validly, published.

The purpose of this announcement is to effect the valid publication of the following new names and new combinations under the procedure described in the Bacteriological Code (1990 Revision). Authors and other individuals wishing to have new names and/or combinations included in future lists should send three copies of the pertinent reprint or photocopies thereof to the IJSEM Editorial Office for confirmation that all of the other requirements for valid publication have been met. It is also a requirement of IJSEM and the ICSP that authors of new species, new subspecies and new combinations provide evidence that types are deposited in two recognized culture collections in two different countries (i.e. documents certifying deposition and availability of type strains). It should be noted that the date of valid publication of these new names and combinations is the date of publication of this list, not the date of the original publication of the names and combinations. The authors of the new names and combinations are as given below, and these authors' names will be included in the author index of the present issue and in the volume author index. Inclusion of a name on these lists validates the publication of the name and thereby makes it available in bacteriological nomenclature. The inclusion of a name on this list is not to be construed as taxonomic acceptance of the taxon to which the name is applied. Indeed, some of these names may, in time, be shown to be synonyms, or the organisms may be transferred to another genus, thus necessitating the creation of a new combination.

Bacteria↗

PubMed2002

Name change among offender patients: an English high security hospital sample.

BACKGROUND: There is scant literature on change of name among psychiatric patients but a more substantial amount on the use of aliases among offenders. No one to our knowledge has explored name changes among offender patients. AIM: This study was undertaken to establish the prevalence of name change among high security hospital patients and to compare those who changed name with those who did not. HYPOTHESIS: It was hypothesized that name change would be associated with male gender, repeated offending and a diagnosis of personality disorder. METHOD: The clinical records of all patients resident in one high security hospital on 31 January 2000 were searched. As all such patients are compulsorily detained, all name changes must be recorded. Any change prior to that date was also noted, together with basic demographic and diagnostic information; supplementary data were obtained from the special hospitals' case register. RESULTS: Seventy-one patients (17%) of the resident population changed names (exclusive of a woman changing her surname on marriage). Name changing was associated with disrupted upbringing. Patients with personality disorder were more likely to change names than those with psychosis, regardless of sex, age or ethnic group. Those with psychosis were more likely to select unusual or symbolic names. CONCLUSIONS: On the evidence of previous literature, people from this serious offender patient population were more likely to change names than other psychiatric patients but less likely than non-mentally-disordered offenders. Changes by people with psychosis seemed related to their illness, whereas changes by those with personality disorder might reflect childhood disruptions in rearing patterns.

Adult↗

PubMed1997

Putting faces to names.

An experiment is reported which investigated participants' ability to remember a person's face when they were presented with the person's name. During the learning phase, participants were shown 18 unfamiliar faces together with a name and occupation. At test, participants were presented with a name and were asked to indicate the face and occupation that had been presented with that name at learning. Results showed that participants' ability to remember the face was contingent upon their ability to remember the occupation that had been presented with the name. When participants were presented with a face and were asked to remember the name, performance was also contingent upon correctly remembering the associated occupation, consistent with the findings of McWeeny, Young, Hay & Ellis (1987). No such contingencies were apparent when participants were given an occupation and were asked to remember the associated name and face; participants frequently remembered the name but not the face, or the face without the name. These results are consistent with the serial access model of person identification proposed by Bruce & Young (1986), and with more recent developments proposed by Valentine, Brédart, Lawson & Ward (1991) and Craigie & Hanley (1993) in which there are no direct links between the representation of a person's name in memory and visual information about their facial appearance. The mnemonic strategies that were used by the participants during the learning phase of the experiment were also examined. These strategies help explain those few occasions on which participants appear to be able to link names to faces without identity-specific semantic information.

Adolescent↗

PubMed1999

Name-calling and nicknames in a sample of primary school children.

BACKGROUND: Name-calling, unkind nicknames and other forms of verbal harassment represent some of the most prevalent forms of bullying in school but they have been little studied. Name-calling and nicknames in particular are ambiguous social events that can serve positive as well as negative goals, and their adverse consequences can be difficult to identify. AIMS: (i) To assess the incidence of nicknames and name calling as reported by a sample of primary school children; (ii) to examine the kinds of names reported by children, and to relate these to names reported in other social contexts; (iii) to explore the impact that name-calling and nicknames have on children. SAMPLE: Pupils (N = 60) from the top two classes in a British primary school completed a questionnaire; 20 of the children were subsequently interviewed. METHOD: Pupils completed a questionnaire that was constructed for this study. Pupils were asked to provide examples of nicknames and to report on the types and incidence of several forms of verbal harassment. The interview included questions which aimed to explore the children's reactions to harassment. RESULTS: Being called disliked nicknames, called names, teased, and other forms of verbal harassment were reported by most of the sample, with more than 20% of children experiencing nasty comments and unkind nicknames on a daily basis. Girls reported more disliked nicknames than boys. The most common nicknames referred to the child's appearance, whereas nasty comments and untrue stories contained a preponderance of sexual references. In the interview, nearly all children reported that being called names and nicknames were negative experiences that caused distress. CONCLUSIONS: Name-calling and the assignment of unkind nicknames are prevalent and hurtful++ features of school life. The kinds of names are similar to those reported in other studies of children, adolescents, and adults. It is proposed that these names are hurtful because they threaten the child's identity.

Child↗

PubMed2002

Name signs in Greek sign language.

Name signs have existed in Greek Deaf culture since antiquity. However, little is known about Greek Sign Language (GSL) and the Greek Deaf community. Based on interviews with 200 people, the phonological characteristics of Greek name signs are described, as well as the frequency of occurrence of specific name signs and the influence of spoken Greek. Comparisons are made with American Sign Language and the naming process in general Greek culture. The Greek Deaf community uses both types of name signs, descriptive name signs (DNS) and arbitrary name signs (ANS). The most popular form of naming uses the DNS process. Name signs are not passed down within families but are assigned by members of the Deaf community or by Deaf peers in the educational setting. Once a name sign has been assigned it stays with the recipient, usually for life. Traditionally, most name signs describe personal characteristics, but with many hearing people now learning GSL, initialized signs are appearing. Whether the Greek Deaf community will accept this practice remains uncertain.

Culture↗

PubMed2006

Phonological cues influence sex decisions about novel names.

Investigations of first names in English have found that male and female names are distinguished by different phonological characteristics. This paper reports on findings that suggest native speakers of English rely on those same cues when making judgments about the sex of names with which they are unfamiliar. When presented with 40 novel, i.e., "invented" names, 25 university undergraduates judged one-syllable names and consonant-final names as male names; however, they judged two-syllable names and vowel-final names as female names. These findings indicate that certain phonological features are strong enough predictors of sex that they can be used to designate sex even with names never before encountered.

Adolescent↗

PubMed2003

Bromocriptine and quinpirole, but not 7-OH-DPAT or SKF 38393, potentiate the inhibitory effect of L-NAME on ethanol-induced locomotor activity in mice.

The effects of N(G)-nitro- l-arginine methyl ester (L-NAME), a nitric oxide synthase inhibitor, SKF 38393, bromocriptine (BRM), quinpirole (QPR) and 7-hydroxy-2-dipropylaminotetralin (7-OH-DPAT), dopamine receptor agonists, and combinations of the dopamine agonists and L-NAME on ethanol-induced locomotor activity in adult male Swiss-Webster mice were investigated. The mice were given ethanol (0.5-2 g/kg), L-NAME (15-60 mg/kg), SKF 38393 (5-20 mg/kg), BRM (2.5 and 5 mg/kg), QPR (0.25 and 0.5 mg/kg), 7-OH-DPAT (0.5 and 1.0 mg/kg), a combination of l-arginine (1 g/kg) and L-NAME (60 mg/kg), combinations of SKF 38393, BRM, QPR or 7-OH-DPAT with L-NAME (60 mg/kg) or ethanol (0.5 g/kg) and saline or vehicle by i.p. injection. Triple combinations (dopaminergic agonist, 60 mg/kg L-NAME and 0.5 g/kg ethanol) were also given. Locomotor activity was measured for 30 min immediately following ethanol injections. Ethanol (0.5 g/kg) significantly increased locomotor activity. L-NAME, BRM, QPR and 7-OH-DPAT blocked the ethanol (0.5 g/kg)-induced locomotor hyperactivity dose dependently and at doses that did not affect locomotor activity in naive mice when administered alone. The inhibitory effects of L-NAME (60 mg/kg) were not prevented by pretreatment with l-arginine. BRM and QPR, but not 7-OH-DPAT, significantly and dose-dependently potentiated the inhibitory effect of L-NAME. Our results suggest that L-NAME inhibits ethanol-induced locomotor hyperactivity in mice by a mechanism not involving NO. The inhibitory effect of L-NAME may be related to the activation of presynaptic dopamine D(2) receptors rather than dopamine D(3) receptors.

2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-ben↗

PubMed1993

Recognition and naming of famous faces in Alzheimer's disease: a cognitive analysis.

A Famous Faces Test designed to assess face recognition, spontaneous naming, verbal identification of un-named faces, and cued naming using semantic and phonetic cues was administered to 22 patients with dementia of Alzheimer type (DAT) and 25 matched controls. The DAT patients were significantly impaired in all test conditions with evidence of a temporal gradient for recognition, identification and naming with phonemic cues, but not for spontaneous naming or naming with semantic cues. Analysis of the effects of disease severity showed that performance in all five conditions of the test declined with increasing disease severity, but this did not reach significance for recognition or for naming with phonemic cues. The DAT patients identified and named a significantly smaller proportion of the faces that they recognized than did the controls, and at no stage was identification significantly better than spontaneous naming. These findings indicate that the primary deficit was not one of name access, but an actual loss of stored knowledge about the person represented. In keeping with this observation, semantic cueing did not aid naming. These findings are discussed in the context of contemporary cognitive models of face processing.

Aged↗

PubMed2005

Dissociable roles of the bilateral anterior temporal lobe in face-name associations: an event-related fMRI study.

Previous studies have suggested the importance of bilateral anterior temporal regions in face-name associations, but there is little evidence concerning their precise role. In this fMRI study, we investigated the effects of person-related semantics (PS) and repeated learning (R) on activations in these regions during the retrieval of face-name associations. For encoding stimuli, we prepared four lists of faces. To control the factor of PS, people's and occupation names were attached to the faces in lists A and B, whereas only people's names were attached to the faces in lists C and D. To control the factor of R, the stimuli in lists A and C were learned twice, whereas the stimuli in lists B and D were learned seven times during encoding before fMRI. During fMRI after the encoding, subjects participated in the retrieval task of people's names from faces or in the retrieval task of faces from people's names. The left anterior temporal lobe was significantly activated during the retrieval of people's names from faces encoded with, compared to without, PS; whereas the right anterior temporal lobe was activated during the retrieval of people's faces from names, compared to without, this encoding. Also, activation of the left (but not the right) anterior temporal lobe was significantly reduced after R of face-name associations. These findings suggest that the three components of faces, names, and PS may be mutually mediated by the bilateral anterior temporal lobe, whose activity may be dynamically changed by the level of consolidation of face-name associations.

Adult↗

PubMed2000

The effects of L-NAME on vestibular compensation and NOS activity in the vestibular nucleus, cerebellum and cortex of the guinea pig.

Nitric oxide (NO) has been implicated in the processes by which animals recover from peripheral vestibular damage ('vestibular compensation'). However, few data exist on the dose-response effects of systemic administration of the nitric oxide synthase (NOS) inhibitor, N(G)-nitro-L-arginine methyl ester (L-NAME), on the vestibular compensation process. The aim of this study was to investigate the effects on compensation of 5, 10, 50 or 100 mM L-NAME administered by s.c osmotic minipump for 50 h following unilateral vestibular deafferentation (UVD) in guinea pig, either commencing the drug treatment at 4 h pre-UVD or at the time of the UVD (i.e., post-UVD). Post-UVD treatment with L-NAME, at any of the four concentrations used, had no effect on the compensation of spontaneous nystagmus (SN), yaw head tilt (YHT) or roll head tilt (RHT). By contrast, pre-UVD treatment with 100 mM L-NAME resulted in a significant decrease in SN frequency (P<0.05) and a change in the rate of its compensation (P<0.0005). Pre-UVD L-NAME resulted in a significant increase in the overall magnitude of YHT (P<0.005); however, post-hoc comparisons revealed no significant differences between any specific L-NAME and vehicle groups. Pre-UVD L-NAME had no effect on RHT at any concentration. Analysis of NOS activity in the pre-UVD L-NAME treatment groups at 50 h post-UVD showed that only 100 mM L-NAME resulted in a significant decrease in NOS activity in the contralateral medial vestibular nucleus (MVN)/prepositus hypoglossi (PH) (P<0.05) and that NOS activity in the ipsilateral MVN/PH was not significantly affected. However, NOS activity was significantly inhibited in the bilateral cerebellum and cortices for several concentrations of L-NAME. These results suggest that pre-UVD systemic administration of L-NAME can significantly increase the rate of SN compensation in guinea pig and that this effect is correlated with inhibition of NOS activity in several regions of the CNS.

Animals↗